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Day-to-Day Impact Of Vaginal Aging Questionnaire: A Multidimensional Measure Of The Impact Of Vaginal Symptoms On Functioning And Well-being In Postmenopausal Women

A. Huang, S. Gregorich, M. Kuppermann, Sanae Nakagawa, S. K. Van Den Eeden, J. Brown, H. Richter, L. Walter, D. Thom, A. Stewart
Published 2015 · Medicine

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ObjectiveThis study aims to develop a self-report questionnaire assessing the impact of vaginal dryness, soreness, itching, irritation, and pain on functioning and well-being in postmenopausal women. MethodsStructured self-report items were developed to address the impact of vaginal symptoms on functioning and well-being based on findings from focus groups with racially/ethnically diverse, symptomatic postmenopausal women. Items were refined after cognitive interview pretesting and field-tested among symptomatic postmenopausal women enrolled in a multiethnic cohort study in California. Exploratory factor analysis (SAS PROC VARCLUS) and confirmatory factor analysis evaluated factor structure and eliminated poorly fitting items. Additional evidence of construct validity was obtained via examination of correlations with other measures of related constructs. Internal consistency and test-retest reliability were assessed using Cronbach &agr; and correlation coefficients, respectively. ResultsFor the 745 postmenopausal women who completed the draft questionnaire, the mean (SD) age was 56.2 (8.5) years, and 66% of the respondents were racial/ethnic minorities. The refined questionnaire included four multi-item scales addressing symptom impact on (1) activities of daily living, (2) emotional well-being, (3) sexual functioning, and (4) self-concept and body image. The four-factor model provided good approximate fit (comparative fit index, 0.987; standardized root-mean-square residual, 0.038). Correlations with other measures of symptom bothersomeness, sexual function, depression, and anxiety conformed to hypotheses. Cronbach &agr; values ranged from 0.82 to 0.93. Intraclass coefficients ranged from 0.47 to 0.72. ConclusionsThe Day-to-Day Impact of Vaginal Aging questionnaire is a new multidimensional self-report measure designed to facilitate evaluation of the impact of vaginal symptoms on postmenopausal women of diverse backgrounds.
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