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The Regulation Of Fatty Acid Biosynthesis In Some Estuarine Strains Of Flexibacter

P. Intriago
Published 1992 · Biology

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Summary: The mechanism of unsaturated fatty acid biosynthesis in two estuarine strains of Flexibacter was investigated. Addition of cyclic AMP (cAMP) inhibited the incorporation of radiolabeled acetate into fatty acids of lateexponential phase cultures of strain Inp2. Cerulenin selectively inhibited the incorporation of radioactive acetate into the major fatty acid, 16:1. When Flexibacter strain Inp3 was grown in a medium of high osmotic strength, polyunsaturated fatty acids were present, but they were absent from cultures grown in media with an osmotic strength close to that of sea water. Addition of cAMP to cultures growing at high osmotic strength suppressed the formation of polyunsaturated fatty acids; the uncoupler 2,4-dinitrophenol had a similar effect. The findings are discussed in the context of the suggestion made by Intriago and Floodgate (Journal of General Microbiology 137, 1503–1509, 1991) that Flexibacter strains possess both the anaerobic and aerobic pathways for unsaturated fatty acid biosynthesis, the activity of the latter being modulated by the intracellular concentration of cAMP.
This paper references
10.1099/00221287-137-7-1503
Fatty acid composition of the estuarine Flexibacter sp. strain Inp: effect of salinity, temperature and carbon source for growth
P. Intriago (1991)
10.1016/0005-2736(85)90178-6
Electron spin resonance studies of lipid fluidity changes in membranes of an uncoupler-resistant mutant of Escherichia coli.
F. Herring (1985)
10.1080/03602548508068412
Application of Phenacyl Derivatives for the Determination of Fatty Acids by HPLC
S. Lam (1985)
10.1128/JB.114.3.1068-1073.1973
Cyclic adenosine 3',5'-monophosphate in Escherichia coli.
M. Büttner (1973)
10.1128/JB.169.10.4479-4485.1987
Incorporation of specific exogenous fatty acids into membrane lipids modulates protonophore resistance in Bacillus subtilis.
T. A. Krulwich (1987)
10.1007/978-3-662-13187-9_19
Introduction to the Gliding Bacteria
H. Reichenbach (1981)
10.1021/BI00680A003
Different cyclic adenosine 3',5'-monophosphate requirements for induction of beta-galactosidase and tryptophanase. Effect of osmotic pressure on intracellular cyclic adenosine 3,5-monophosphate concentrations.
M. Piovant (1975)
10.2331/SUISAN.54.1835
Eicosapentaenoic acid productivity of the bacteria isolated from fish intestines
K. Yazawa (1988)
10.1016/s0021-9258(18)63085-6
The biosynthesis of unsaturated fatty acids by bacilli. II. Temperature-dependent biosynthesis of polyunsaturated fatty acids.
A. Fulco (1970)
10.1099/00221287-131-1-17
The effect of growth conditions on adenylate cyclase activity and virulence-related properties of Bordetella pertussis.
R. M. Brownlie (1985)
10.1128/JB.117.2.432-438.1974
Cyclic adenosine 3',5'-monophosphate and morphogenesis in Mucor racemosus.
A. Larsen (1974)
10.1016/0014-5793(85)80705-5
Cyclic AMP independence of Escherichia coli protein phosphorylation
M. Dadssi (1985)
10.1099/00221287-134-2-359
Aspects of the regulation of adenylate cyclase synthesis in Escherichia coli K12.
A. Roy (1988)
10.1016/0163-7827(83)90005-X
Fatty acid metabolism in bacteria.
A. Fulco (1983)
10.1016/0014-5793(85)81205-9
The site of cyclic AMP‐dependent protein kinase catalyzed phosphorylation of cytochrome P‐450 LM2
R. Mueller (1985)
10.1128/AEM.51.4.730-737.1986
Biochemical function and ecological significance of novel bacterial lipids in deep-sea procaryotes.
E. DeLong (1986)
10.1128/JB.171.8.4267-4271.1989
Mechanism of biosynthesis of unsaturated fatty acids in Pseudomonas sp. strain E-3, a psychrotrophic bacterium.
M. Wada (1989)
10.1099/00221287-134-5-1275
Demonstration of two protein kinases in extracts of Legionella micdadei.
A. Saha (1988)
10.1128/JB.117.3.1178-1183.1974
Fatty acid degradation in Escherichia coli: requirement of cyclic adenosine monophosphate and cyclic adenosine monophosphate receptor protein for enzyme synthesis.
G. Pauli (1974)
10.1016/s0021-9258(19)63397-1
Unsaturated fatty acids in microorganisms.
G. Scheurbrandt (1962)
10.1128/JB.172.2.1133-1136.1990
Regulation of phospholipid biosynthesis in Saccharomyces cerevisiae by cyclic AMP-dependent protein kinase.
A. Kinney (1990)
10.1016/0003-9861(76)90511-7
Regulation of membrane functions and fatty acid composition in Escherichia coli by cyclic AMP receptor protein.
W. Dallas (1976)
10.1099/00221287-133-8-2191
Regulation of the cAMP level in the yeast Saccharomyces cerevisiae: intracellular pH and the effect of membrane depolarizing compounds.
J. Thevelein (1987)
10.1016/s0021-9258(19)61705-9
On the origin of unsaturated fatty acids in clostridia.
H. Goldfine (1961)
10.1139/O59-099
A rapid method of total lipid extraction and purification.
E. Bligh (1959)
10.1021/BI00617A031
Inhibition of unsaturated fatty acid synthesis in escherichia coli by the antibiotic cerulenin.
T. Buttke (1978)
10.1016/0005-2760(73)90241-5
Inhibition of fatty acid synthesis by the antibiotic cerulenin. Specific inactivation of beta-ketoacyl-acyl carrier protein synthetase.
G. D'agnolo (1973)
10.1126/SCIENCE.143.3610.1006
BIOSYNTHESIS OF UNSATURATED FATTY ACIDS IN MICROORGANISMS.
J. Erwin (1964)



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