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Characteristics Of Hemolytic And Hemagglutinating Activities Of Treponema Denticola.

D. Grenier
Published 1991 · Biology, Medicine

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Treponema denticola, a suspected periodontal pathogen, was shown to agglutinate and lyse human red blood cells. Both activities were cell-associated, heat-labile, and produced during the exponential growth phase. Hemolytic activity was time-dependent and required incubation at 37 degrees C; further incubation at 4 degrees C increased the hemolysis. Hemagglutination was reduced in the presence of D-glucosamine, EDTA or sodium salicylate, whereas hemolytic activity was affected by calcium chloride, magnesium chloride, EDTA or sodium salicylate. These biological activities may favor a higher concentration of hemin-containing compounds in periodontal sites, and therefore represent additional potential virulence mechanisms.
This paper references
10.1111/J.1600-0765.1985.TB00403.X
Bacteriological studies of subgingival plaque in a periodontitis-resistant population. I. Darkfield microscopic studies.
C. Africa (1985)
10.1128/IAI.48.2.507-519.1985
Comparative bacteriology of juvenile periodontitis.
W. Moore (1985)
10.1111/J.1600-0765.1987.TB01595.X
Microbiology of periodontal disease.
W. Moore (1987)
10.1038/243234A0
Salicylates and Phospholipid Bilayer Membranes
S. McLaughlin (1973)
10.1111/J.1600-051X.1986.TB00878.X
Serum IgA and IgG antibodies to Treponema vincentii and Treponema denticola in adult periodontitis, juvenile periodontitis and periodontally healthy subjects.
C. Lai (1986)
10.1128/IAI.55.12.3209-3212.1987
Phospholipase D activity of Vibrio damsela cytolysin and its interaction with sheep erythrocytes.
A. Kreger (1987)
10.1177/00220345870660120601
Adherence of Treponema denticola to Modified Hydroxyapatite
G. Cimasoni (1987)
10.1128/IAI.51.2.642-647.1986
Adherence of oral treponemes and their effect on morphological damage and detachment of epithelial cells in vitro.
F. Reijntjens (1986)
10.1111/J.1600-0722.1984.TB00860.X
Attachment of Treponema denticola to cultured human epithelial cells.
I. Olsen (1984)
10.1128/IAI.34.3.1071-1074.1981
Studies of phospholipase C (heat-labile hemolysin) in Pseudomonas aeruginosa.
R. Berka (1981)
10.1128/IAI.58.2.347-351.1990
Cellular location of a Treponema denticola chymotrypsinlike protease and importance of the protease in migration through the basement membrane.
D. Grenier (1990)
10.1111/J.1574-6968.1989.TB03397.X
Microbial lectin cofunction with lytic activities as a model for a general basic lectin role.
N. Gilboa-Garber (1989)
10.1111/J.1600-0765.1982.TB01140.X
Detection of elevated serum antibodies to Treponema denticola in humans with advanced periodontitis by an enzyme-linked immunosorbent assay.
E. Jacob (1982)
10.1139/M65-061
FACTORS AFFECTING THE SENSITIZATION OF SHEEP ERYTHROCYTES TO STAPHYLOCOCCAL BETA LYSIN.
G. Wiseman (1965)
10.1111/J.1399-302X.1988.TB00092.X
Degradation of basement membrane collagen by proteases from some anaerobic oral micro-organisms.
V. Uitto (1988)
10.1111/j.1365-2958.1989.tb00228.x
Analysis of a cloned sequence of Legionella pneumophila encoding a 38 kD metalloprotease possessing haemolytic and cytotoxic activities
F. Quinn (1989)
10.1128/IAI.45.1.155-159.1984
Suppression of fibroblast proliferation by oral spirochetes.
H. Boehringer (1984)
10.1128/IAI.57.3.732-738.1989
Characterization of a Legionella pneumophila extracellular protease exhibiting hemolytic and cytotoxic activities.
M. G. Keen (1989)
10.1111/J.1399-302X.1988.TB00009.X
Effect of hemoglobin and of ferric ammonium citrate on the virulence of periodontopathic bacteria.
S. Mukherjee (1988)
10.1016/0003-9969(83)90109-7
Haemolysis of human erythrocytes by the Fusobacterium nucleatum associated with periodontal disease.
W. Falkler (1983)
10.1128/JCM.12.6.792-795.1980
Rifampin as a selective agent for isolation of oral spirochetes.
S. Leschine (1980)
10.1111/j.1348-0421.1985.tb00862.x
Some Properties of Vibrio vulnificus Hemolysin
S. Shinoda (1985)



This paper is referenced by
10.1016/S0923-2508(02)00003-7
Hemolytic activity of Prevotella intermedia and Prevotella nigrescens strains: influence of abiotic factors in solid and liquid assays.
T. A. Silva (2003)
10.1034/J.1399-302X.2000.150101.X
Taxonomy and virulence of oral spirochetes.
E. Chan (2000)
The prevalence of protozoa during canine periodontal disease
N. Patel (2019)
10.1128/IAI.70.3.1113-1120.2002
Role of Glutathione Metabolism of Treponema denticola in Bacterial Growth and Virulence Expression
L. Chu (2002)
10.1016/J.FEMSRE.2003.10.004
Outer membrane proteins of pathogenic spirochetes.
P. Cullen (2004)
10.1177/10454411010120050301
Role of Treponema denticola in periodontal diseases.
M. Sela (2001)
10.1007/s004300050008
The peptidolytic capacity of the spirochete system
K. Mäkinen (1996)
10.1006/ANAE.1997.0131
Virulence factors of oral treponemes.
J. Fenno (1998)
10.1111/J.1600-0757.2005.00108.X
Spirochetes at the forefront of periodontal infections.
R. Ellen (2005)
10.1080/00015550260132442
Treponema pallidum induces up-regulation of interstitial collagenase in human dermal fibroblasts.
K. Y. Chung (2002)
10.1111/j.1348-0421.1999.tb02434.x
Molecular Analysis for Pathogenicity of Oral Treponemes
K. Ishihara (1999)
10.2329/PERIO.34.323
成人性歯周炎の歯齦縁下プラークにおけるPorphyromonas gingivalis, Treponema denticolaの局在に関する免疫組織化学的検索
隆司 木暮 (1992)
10.1111/J.0906-6713.2004.003559.X
Antigens of bacteria associated with periodontitis.
N. O'Brien-Simpson (2004)
10.1099/mic.0.000896
Characterization of the hemolytic activity of Riemerella anatipestifer.
Yanshan Gong (2020)
10.1128/IAI.66.2.696-702.1998
Filamentous Actin Disruption and Diminished Inositol Phosphate Response in Gingival Fibroblasts Caused byTreponema denticola
P. Yang (1998)
10.5051/JKAPE.2003.33.1.79
Effect of sonicates of Treponema denticola on osteoblast differentiation
Bong-Kyu Choi (2003)
10.1128/IAI.65.11.4888-4891.1997
Cloning, expression, and sequencing of a protease gene from Bacteroides forsythus ATCC 43037 in Escherichia coli.
T. Saito (1997)
10.1128/IAI.64.8.2904-2910.1996
The major surface protein complex of Treponema denticola depolarizes and induces ion channels in HeLa cell membranes.
D. Mathers (1996)
10.1177/00220345960750121101
Membrane Components of Treponema denticola Trigger Proteinase Release from Human Polymorphonuclear Leukocytes
Y. Ding (1996)
10.1099/00221287-146-2-497
A flagellar gene cluster from the oral spirochaete Treponema maltophilum.
K. Heuner (2000)
10.1034/J.1399-302X.1999.140505.X
Hemoxidation and binding of the 46-kDa cystalysin of Treponema denticola leads to a cysteine-dependent hemolysis of human erythrocytes.
L. Chu (1999)
10.1139/M96-137
Iron acquisition by oral hemolytic spirochetes: isolation of a hemin-binding protein and identification of iron reductase activity.
D. Scott (1996)
10.1046/J.0143-2885.2003.00607.X
Oral treponemes in primary root canal infections as detected by nested PCR.
I. N. Rôças (2003)
Les polyphénols du thé vert : des molécules à double action contre la maladie parodontale
Marie-Pierre Morin (2015)
10.1111/J.1399-302X.1993.TB00566.X
Involvement of treponemal surface-located protein and carbohydrate moieties in the attachment of Treponema denticola ATCC 33520 to cultured rat palatal epithelial cells.
R. Keulers (1993)
10.14288/1.0103814
Effects of treponema denticola on an oral epithelial cell model
W. Leung (1998)
10.1016/J.JOB.2013.04.002
Hemolysin of Prevotella oris: Purification and characteristics
T. Sato (2013)
10.1111/J.1600-0765.1993.TB01071.X
Characterization of the wheat germ agglutinin-binding property of Treponema denticola.
D. Grenier (1993)
10.1111/J.1574-6968.1993.TB06585.X
Hemolytic toxin produced by Porphyromonas gingivalis.
M. Hoshi (1993)
10.1111/J.1399-302X.1993.TB00568.X
Binding of hemin and congo red by oral hemolytic spirochetes.
D. Scott (1993)
10.1016/j.anaerobe.2012.04.005
Contribution of hly homologs to the hemolytic activity of Prevotella intermedia.
N. Suzuki (2012)
10.1016/0196-4399(94)90024-8
Spirochetes in periodontal disease
G. Riviere (1994)
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