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Evaluation Of Alternatives To Malachite Green Oxalate As A Therapeutant For Ichthyophthiriosis In Rainbow Trout Oncorhynchus Mykiss

T. Wahli, M. Schmitt, W. Meier
Published 1993 · Biology

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Summary Malachite green, the drug most commonly used against ichthyophthiriosis, is suspected to be carcinogenic and mutagenic. Therefore, the use of this de is restricted or rohibited in several countries. In order to find an alternative, the in vitro effect of the following substances on different stages of Ichthyophthirius multifilis (tomont, cyst and tomite) was investigated: Amphotericin B, chloram-phenicol, chlortetracycline, dimetridazole, formalin, furazolidone, oxytetracycline and sulfachlorpy-razine, and as controls malachite green and mixtures of malachite green and formalin. In vitro, Amphothericin B, chlortetracycline, formalin and mixtures of malachite green and formalin showed the same potential as malachite green. Furazolidone inhibited the development of theronts but was relatively ineffective against emerged theronts. Little or no parasiticidal effect could be attributed to chloramphenicol, dimetridazole, oxytetracline or sulfachlorpyrazine. The substances, which had proved all highly effective in vitro, were subsequently examined in vivo in a bath treatment and/or using medicated diets. Thereby successful treatment was achieved only with malachite green and mixtures of malachite green and formalin. All other substances were either ineffective or their use resulted in increased mortality (formalin).
This paper references
10.1577/1548-8659(1983)45[164:AODBHO]2.0.CO;2
Administration of Drugs by Hyperosmotic or Vacuum Infiltration or Surfactant Immersion Ineffective for Control of Intradermally Encysted Ichthyophthirius multifiliis
G. Post (1983)
[Occurrence and significance of Ichthyophthirius multifiliis in Switzerland].
T. Wahli (1987)
10.1111/J.1365-2761.1991.TB00616.X
A new approach to controlling ichthyophthiriasis in a closed culture system of freshwater ornamental fish
K. Ling (1991)
10.1111/J.1365-2761.1979.TB00415.X
Observations on diseases and parasites of mullet alevins Mugil cephalus L. from the Rio Moche coastal lagoon of Peru
Gina Armas (1979)
Trials with toltrazuril against Ichthyophthirius multifiliis Fouquet, 1876
J. From (1992)
10.1111/J.1439-0426.1991.TB00603.X
Affinity of Ichthyophthirius multifiliis theronts to light and/or fish
T. Wahli (1991)
10.1577/1548-8640(1947)9[21:IIATH]2.0.CO;2
Ichthyophthiriasis in Australian Trout Hatchery
A. D. B. B.Sc. (1947)
10.1111/J.1365-2761.1980.TB00444.X
Attempts to control Ichthyophthirius multifiliis Fouquet (Ciliophora: Ophryoglenidae) by chemotherapy and electrotherapy
D. Farley (1980)
[Problems with malachite green use in fish].
M. Kietzmann (1990)
10.1139/F82-228
Ichthyophthiriasis: Immersion Immunization of Rainbow Trout (Salmo gairdneri) Using Tetrahymena thermophila as a Protective Immunogen
K. Wolf (1982)
10.1577/1548-8659(1983)112<818:TAOEOM>2.0.CO;2
Teratological and Other Effects of Malachite Green on Development of Rainbow Trout and Rabbits
F. Meyer (1983)
10.1111/J.1365-2761.1987.TB00725.X
The effects of malachite green upon proliferative kidney disease
R. Clifton-Hadley (1987)
Aufnahme und Ausscheidung von Malachitgrün bei Regenbogenforellen
K. Bauer (1988)
10.1577/1548-8640(1972)34[162:IBIMOF]2.0.CO;2
Infection by Ichthyophthirius Multifiliis of Fish in Uganda
I. Paperna (1972)
10.1111/J.1095-8649.1980.TB02764.X
Protection of channel catfish, Ictalurus punctatus Rafmesque, against Ichthyophthirius multifiliis Fouquet by immunization
B. A. Goven (1980)
10.1111/J.1365-2761.1985.TB00945.X
Malachite green: a review
D. J. Alderman (1985)
10.1111/J.1095-8649.1973.TB04484.X
Ichthyophthiriasis in the mirror carp
R. S. Hines (1973)
10.1111/J.1365-2761.1991.TB00607.X
Pathological effects of repeated doses of malachite green: a preliminary study.
N. Gerundo (1991)
10.1577/1548-8640(1989)051<0127:SOCTCP>2.3.CO;2
Screening of Chemicals to Control Protozoan Parasites of Fish
B. R. Griffin (1989)
10.1577/1548-8640(1972)34[165:AROMTC]2.0.CO;2
A Review of Methods to Control Ichthyophthiriasis
D. Cross (1972)
Parasites of Fresh Water Fishes.
R. Rehana (1979)
10.1002/ANGE.19510631318
Handbuch der Frischwasser‐ und Abwasserbiologie (Biologie des Trinkwassers, Badewassers, Fischwassers, Vorfluters und Abwassers), von H. Liebmann, Bd. 1. Verlag R. Oldenbourg, München 1951. 539 S., 436 Abb., 5 Farb‐ u. 13 Schwarzweißtafeln, Olwd. DM 54.–
K. Bernhauer (1951)
10.1577/1548-8640(1988)050<0190:TITRNT>2.3.CO;2
The Impetus to Register New Therapeutants for Aquaculture
R. Schnick (1988)
10.1577/1548-8640(1936)318[7:TUOMGA]2.0.CO;2
The Use of Malachite Green as a Fish Fungicide and Antiseptic
F. Foster (1936)
10.1111/J.1365-2761.1981.TB01150.X
Ichthyophthiriasis of Atlantic salmon, Salmo salar L., at the Montta Hatchery in northern Finland in 1978–1979
E. T. Valtonen (1981)
10.1007/BF00684337
Strukturveränderungen an Chromosomen durch Malachitgrün
H. Keyl (2004)



This paper is referenced by
10.1007/s00436-003-1038-8
Effects of crude extracts of Mucuna pruriens (Fabaceae) and Carica papaya (Caricaceae) against the protozoan fish parasite Ichthyophthirius multifiliis
A. Ekanem (2003)
10.3354/dao02105
Toxicity of peracetic acid (PAA) to tomonts of IIchthyophthirius multifiliis.
T. Meinelt (2009)
10.3354/dao02360
Efficacy of quinine against ichthyophthiriasis in common carp Cyprinus carpio.
I. V. Schumacher (2011)
10.1016/j.ijpddr.2015.04.001
In vitro and in vivo assessment of the effect of antiprotozoal compounds isolated from Psoralea corylifolia against Ichthyophthirius multifiliis in fish
Kaige Song (2015)
10.1016/J.AQUAENG.2009.07.002
Mechanical control of Ichthyophthirius multifiliis Fouquet, 1876 (Ciliophora) in a rainbow trout hatchery.
Andrew P. Shinn (2009)
10.1007/s00436-010-1966-z
Effect of sanguinarine from the leaves of Macleaya cordata against Ichthyophthirius multifiliis in grass carp (Ctenopharyngodon idella)
Jia-Yun Yao (2010)
10.1002/ps.2293
The potential utility of the leopard pleco (Glyptoperichthys gibbiceps) as a biological control of the ciliate protozoan Ichthyophthirius multifiliis.
S. M. Picón-Camacho (2012)
10.1007/s40011-019-01083-z
Description of Protozoan Parasites Parasitizing Gold Fishes and Their Possible Control by Herbal Extracts
Mandira Saha (2019)
10.1016/j.vetpar.2011.07.021
Antiparasitic efficacy of dihydrosanguinarine and dihydrochelerythrine from Macleaya microcarpa against Ichthyophthirius multifiliis in richadsin (Squaliobarbus curriculus).
Jia-Yun Yao (2011)
10.1590/S0103-84782006000300047
Survival and behavior of silver catfish, Rhamdia quelen, submitted to antibiotics and sodium chloride treatments
L. S. Andrade (2006)
10.1016/j.vetpar.2011.11.022
Effects of long duration, low dose bronopol exposure on the control of Ichthyophthirius multifiliis (Ciliophora), parasitising rainbow trout (Oncorhynchus mykiss Walbaum).
S. M. Picón-Camacho (2012)
10.1016/J.AQUAENG.2014.08.002
Evaluation of treatment methods using sodium percarbonate and formalin on Australian rainbow trout farms
J. M. Forwood (2014)
10.1007/s00436-015-4325-2
Evaluation of nystatin isolated from Streptomyces griseus SDX-4 against the ciliate, Ichthyophthirius multifiliis
Jia-Yun Yao (2015)
Development of a Health Management Strategy for the Silver Perch Aquaculture Industry
S. Rowland (2007)
10.1016/j.fsi.2017.06.044
The fish parasite Ichthyophthirius multifiliis - Host immunology, vaccines and novel treatments.
L. G. Jørgensen (2017)
10.1007/978-1-4615-4703-7
Xenobiotics in Fish
D. Smith (1999)
10.1007/s00436-014-4020-8
Anti-parasitic activities of specific bacterial extracellular products of Streptomyces griseus SDX-4 against Ichthyophthirius multifiliis
Jia-Yun Yao (2014)
10.1139/CJFAS-54-11-2653
Effects of intermittent hydrogen peroxide exposure on growth and columnaris disease prevention of juvenile rainbow trout (Oncorhynchus mykiss)
D. Speare (1997)
10.1017/S0031182011001867
An assessment of the use of drug and non-drug interventions in the treatment of Ichthyophthirius multifiliis Fouquet, 1876, a protozoan parasite of freshwater fish.
S. M. Picón-Camacho (2012)
10.1080/10454438.2019.1610541
Heavy infection of Ichthyophthirius multifiliis in striped catfish (Pangasianodon hypophthalmus, Sauvage 1878) and its treatment trial by different therapeutic agents in a control environment
M. A. Mamun (2020)
10.1007/s00436-013-3397-0
Antiprotozoal screening of traditional medicinal plants: evaluation of crude extract of Psoralea corylifolia against Ichthyophthirius multifiliis in goldfish
F. Ling (2013)
10.3389/fenvs.2014.00018
Chlorophyllin as a possible measure against vectors of human parasites and fish parasites
P. Richter (2014)
10.1007/s00436-012-2907-9
Effects of aqueous extract of Capsicum frutescens (Solanaceae) against the fish ectoparasite Ichthyophthirius multifiliis
F. Ling (2012)
10.1007/s00436-014-3987-5
Minimum effective concentrations of formalin and sodium percarbonate on the free-living stages of an Australian isolate of Ichthyophthirius multifiliis
J. M. Forwood (2014)
10.1007/s00436-011-2575-1
In vitro assessment of the chemotherapeutic action of a specific hydrogen peroxide, peracetic, acetic, and peroctanoic acid-based formulation against the free-living stages of Ichthyophthirius multifiliis (Ciliophora)
S. M. Picón-Camacho (2011)
10.1016/j.vetpar.2013.08.019
Evaluation of an antiparasitic compound extracted from Galla chinensis against fish parasite Ichthyophthirius multifiliis.
Qizhong Zhang (2013)
10.1007/s00436-012-2893-y
Chlorophyllin for the control of Ichthyophthirius multifiliis (Fouquet)
S. Wohllebe (2012)
10.1007/978-1-4615-4703-7_11
Disposition and Metabolism of Malachite Green and Other Therapeutic Dyes in Fish
S. M. Plakas (1999)
10.1016/S0144-8609(00)00067-4
Assessing chemical compounds for controlling predator ciliates in outdoor mass cultures of the green algae Dunaliella salina
I. Moreno-Garrido (2001)
10.3354/DAO064069
Treatment of ichthyophthiriasis after malachite green. I. Concrete tanks at salmonid farms.
P. Rintamäki-Kinnunen (2005)
10.1111/J.1365-2109.2008.02061.X
Use of formalin and copper to control ichthyophthiriosis in the Australian freshwater fish silver perch (Bidyanus bidyanus Mitchell)
S. Rowland (2008)
10.17221/2027-VETMED
Negative effects of malachite green and possibilities of its replacement in the treatment of fish eggs and fish: a review
E. Sudová (2018)
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