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Gastric Acidity, Atrophic Gastritis, And Calcium Absorption.

R. Wood, C. Serfaty-Lacrosniere
Published 1992 · Chemistry, Medicine

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The deleterious effects of increased gastric pH on calcium absorption from calcium carbonate supplements were observed about 25 years ago. Increasing use of calcium supplements, especially by the elderly, has raised questions about bioavailability from various calcium sources. Decreased gastric acidity is common in the elderly and in patients taking antiulcer medications. A critical review of the available human studies that have investigated the role of gastric acidity in calcium bioavailability suggests that the effects of increased gastric pH are only apparent when poorly soluble calcium salts are taken after an overnight fast. Soluble calcium sources, such as calcium citrate and calcium from milk, are absorbed normally in elderly subjects with atrophic gastritis. Moreover, calcium carbonate, a relatively insoluble calcium salt, is well absorbed in atrophic gastritis patients if administered with a meal. In order to maximize calcium bioavailability, elderly subjects should increase their calcium intakes to at least recommended levels, preferably by increasing milk consumption. When calcium supplements are used to augment dietary calcium sources, a highly soluble source should be of benefit or calcium carbonate may be taken with a meal.
This paper references
10.1172/JCI113283
Role of vitamin D-dependent and vitamin D-independent mechanisms in absorption of food calcium.
M. Sheikh (1988)
10.1079/NRR19890011
Dietary fibre and mineral bioavailability.
B. Harland (1989)
10.1093/ajcn/46.4.699
Effects of glucose and glucose polymers on calcium absorption in healthy subjects.
R. Wood (1987)
10.1056/NEJM198511283132203
Effect of added dietary calcium on colonic epithelial-cell proliferation in subjects at high risk for familial colonic cancer.
M. Lipkin (1985)
10.1093/jn/116.5.768
Effect of metabolizable sugars on the mucosal surface pH of rat intestine.
H. Daniel (1986)
10.1080/07315724.1988.10720266
Effects of pH on mineral-phytate, protein-mineral-phytate, and mineral-fiber interactions. Possible consequences of atrophic gastritis on mineral bioavailability from high-fiber foods.
Champagne Et (1988)
10.1172/JCI111254
An evaluation of the importance of gastric acid secretion in the absorption of dietary calcium.
G. Bo-Linn (1984)
10.1146/annurev.nu.04.070184.002351
Calcium and osteoporosis.
L. Avioli (1984)
10.1016/0016-5085(80)90187-0
Influence of glucose, fructose, and water movement on calcium absorption in the jejunum.
D. A. Norman (1980)
10.1146/annurev.nu.09.070189.001415
Hypochlorhydria: a factor in nutrition.
Z. Kassarjian (1989)
10.1097/00017285-198903000-00007
The Relevance of Mineral Chemistry to Bioavailability
Fergus M. Clydesdale (1989)
10.1152/jappl.1964.19.2.187
ROLE OF HYDROCHLORIC ACID IN IRON ABSORPTION.
P. Jacobs (1964)
10.1056/NEJM198507113130202
Calcium absorption and achlorhydria.
R. Recker (1985)
10.1016/0016-5085(84)90531-6
Effect of meal composition on calcium absorption: Enhancing effect of carbohydrate polymers
S. Kelly (1984)
10.1271/bbb1961.43.2009
An enhanced intestinal absorption of calcium in the rat directly attributed to dietary casein.
Y. Lee (1979)
10.1056/NEJM199009273231305
A controlled trial of the effect of calcium supplementation on bone density in postmenopausal women.
B. Dawson-Hughes (1990)
10.1093/ajcn/53.6.1480
Calcium absorption in elderly subjects on high- and low-fiber diets: effect of gastric acidity.
T. Knox (1991)
10.1093/jn/77.2.155
Absorption of Ca45 and Sr85 from solid and liquid food at various levels of the alimentary tract of the rat.
C. Marcus (1962)
10.7326/0003-4819-66-5-917
The absorption of calcium carbonate.
P. Ivanovich (1967)
10.1093/ajcn/48.6.1471
Response of fractional calcium absorption in women to various coadministered oral glucose doses.
J. Knowles (1988)
10.1126/science.6729459
Blood pressure and nutrient intake in the United States
D. Mccarron (1984)
10.1093/ajcn/44.2.244
Glucose polymer increases jejunal calcium, magnesium, and zinc absorption in humans.
L. Bei (1986)
10.1111/j.1365-2362.1978.tb00857.x
Intestinal and renal handling of calcium in human diabetes mellitus: influence of acute oral glucose loading and diabetic control
L. Monnier (1978)



This paper is referenced by
10.1016/J.AQUACULTURE.2013.11.024
Effect of dietary substitution of fish meal for marine crab and echinoderm meals on growth performance, ammonia excretion, skin colour, and flesh quality and oxidation of red porgy (Pagrus pagrus)
Josefa García-Romero (2014)
10.1111/j.1444-2906.2008.01601.x
Effects of organic acids on growth and phosphorus utilization in rainbow trout Oncorhynchus mykiss
Abhed Pandey (2009)
10.1111/ANU.12135
Dietary calcium requirement in fishes
M. Amir Hossain (2014)
10.1370/afm.1243
Use of Acid-Suppressive Drugs and Risk of Fracture: A Meta-analysis of Observational Studies
Chun-Sick Eom (2011)
10.1023/A:1007757321695
Control of phosphorus homeostasis of Atlantic salmon (Salmo salar) in fresh water
J. Vielma (2004)
10.1111/J.1365-2095.2008.00606.X
Effects of non‐starch polysaccharides enzyme, phytase and citric acid on activities of endogenous digestive enzymes of tilapia (Oreochromis niloticus × Oreochromis aureus)
Jingsong Li (2009)
10.1111/ANU.12673
Growth performance, muscle and liver composition, blood traits, digestibility and gut bacteria of beluga (Huso huso) juvenile fed different levels of soybean meal and lactic acid
H. A. Matani Bour (2018)
10.1016/J.JADA.2009.10.020
Position of the American Dietetic Association: nutrient supplementation.
M. Marra (2009)
10.2165/11536780-000000000-00000
Proton Pump Inhibitors and Fracture Risk
M. Bodmer (2010)
10.1093/GERONA/54.6.M275
Efficacy of calcium supplements on bone mass in postmenopausal women.
K. Chiu (1999)
Dietary Crude Protein, Citric Acid and Microbial Phytase and Their Interacts to Influence Growth Performance, Muscle Proximate Composition and Hematocrite of Common Carp, Cyprinus carpio L, Juveniles
Fateme Khajepour (2012)
10.1385/BMM:2:4:357
Calcium prevention and treatment of osteoporosis
M. B. O'Connell (2004)
10.3382/JAPR/PFZ041
Dietary Enzyme Supplementation in Duck Nutrition: A review
Jung-Woo Park (2019)
PAPEL DEL CALCIO Y DE LA VITAMINA D EN LA SALUD ÓSEA (PARTE II)
A. Sánchez (2003)
10.1007/s11657-019-0659-1
Increased risk of osteoporosis in patients with peptic ulcer: a follow-up study using a national sample cohort
Hyo Geun Choi (2019)
10.3823/2414
Acute Effects Of Oral Calcium Carbonate With And Without The Addition Of Omeprazole And Fiber Enriched Milk On Serum Calcium Concentrations In Postmenopausal Women
Paula Aragão Prazeres Oliveira (2017)
10.2741/1119
Citrate and mineral metabolism: kidney stones and bone disease.
R. Caudarella (2003)
10.1111/J.1753-4887.1998.TB01652.X
Human adult-onset lactase decline: an update.
M. F. Lee (1998)
10.1094/CCHEM.2000.77.3.293
Utilization of Calcium in Breads Highly Fortified with Calcium as Calcium Carbonate or as Dairy Calcium
G. Ranhotra (2000)
10.1111/JAI.13119
Effect of dietary L-malic acid supplementation on growth, feed utilization and digestive function of juvenile GIFT tilapia Oreochromis niloticus (Linnaeus, 1758)
Yong-jun Chen (2016)
10.1093/AJCN/76.6.1345
Relative bioavailability of calcium-rich dietary sources in the elderly.
L. Martini (2002)
10.1111/JWAS.12388
Impact of Dietary L-Malic Acid Supplementation on Growth, Feed Utilization, Ash Deposition, and Hepatic Lipid Metabolism of Juvenile Genetically Improved Farmed Tilapia, Oreochromis niloticus
Yong-jun Chen (2017)
10.1007/s10499-018-0329-0
Dietary acidifiers blend enhanced the production of Nile tilapia (Oreochromis niloticus), striped mullet (Mugil cephalus), and African catfish (Clarias gariepinus) polycultured in earthen ponds
Mohsen Abdel-Tawwab (2018)
10.1111/J.1365-2109.2005.01290.X
Dietary protein level, microbial phytase, citric acid and their interactions on bone mineralization of Labeo rohita (Hamilton) juveniles
K. Baruah (2005)
10.1111/J.1749-7345.2007.00092.X
Interactions of Dietary Microbial Phytase, Citric Acid and Crude Protein Level on Mineral Utilization by Rohu, Labeo rohita (Hamilton), Juveniles
K. Baruah (2007)
10.1177/156482651003100301
High-Calcium Milk Prevents Overweight and Obesity among Postmenopausal Women
I. Angeles-Agdeppa (2010)
10.1016/J.ANIFEEDSCI.2011.10.001
Citric acid improves growth performance and phosphorus digestibility in Beluga (Huso huso) fed diets where soybean meal partly replaced fish meal
F. Khajepour (2012)
10.1111/J.1753-4887.1994.TB01396.X
Safety of some calcium supplements questioned.
S. Whiting (1994)
Long term use of proton pump inhibitors : is there an increase in fracture risk?
Rachel Renee Mutchler (2010)
10.18632/oncotarget.20115
Long non-coding RNA polymorphisms in 6p21.1 are associated with atrophic gastritis risk and gastric cancer prognosis
Zhi Lv (2017)
10.1590/S0004-27302006000500005
Biodisponibilidade do cálcio dietético
E. F. Buzinaro (2006)
10.1016/bs.afnr.2015.09.001
Digestion and Postprandial Metabolism in the Elderly.
Amber M. Milan (2015)
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