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Aberrant Dendritic Cell Function Conditions Th2‐cell Polarization In Allergic Rhinitis

C. Pilette, M. Jacobson, C. Ratajczak, B. Detry, G. Banfield, J. Vansnick, S. Durham, K. Nouri-Aria
Published 2013 · Medicine

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Myeloid (m) and plasmacytoid (p) dendritic cells (DCs) regulate immune responses to allergens, whereas it remains unclear whether abnormal DC function characterizes patients with airway allergy and whether putative dysfunction exists only in target organs. To evaluate DC function from patients with allergic rhinitis (AR), we assessed nasal, cutaneous as well as blood DCs after in vivo and in vitro allergen challenge, respectively.
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