← Back to Search
Current State Of A Dual Behaviour Of Antimicrobial Peptides—Therapeutic Agents And Promising Delivery Vectors
U. Piotrowska, M. Sobczak, E. Oledzka
Published 2017 · Biology, Medicine
Download PDFAnalyze on Scholarcy
Micro‐organism resistance is an important challenge in modern medicine due to the global uncontrolled use of antibiotics. Natural and synthetic antimicrobial peptides (AMPs) symbolize a new family of antibiotics, which have stimulated research and clinical interest as new therapeutic options for infections. They represent one of the most promising antimicrobial substances, due to their broad spectrum of biological activity, against bacteria, fungi, protozoa, viruses, yeast and even tumour cells. Besides, being antimicrobial, AMPs have been shown to bind and neutralize bacterial endotoxins, as well as possess immunomodulatory, anti‐inflammatory, wound‐healing, angiogenic and antitumour properties. In contrast to conventional antibiotics, which have very defined and specific molecular targets, host cationic peptides show varying, complex and very rapid mechanisms of actions that make it difficult to form an effective antimicrobial defence. Importantly, AMPs display their antimicrobial activity at micromolar concentrations or less. To do this, many peptide‐based drugs are commercially available for the treatment of numerous diseases, such as hepatitis C, myeloma, skin infections and diabetes. Herein, we present an overview of the general mechanism of AMPs action, along with recent developments regarding carriers of AMPs and their potential applications in medical fields.
This paper references
Reduced cytotoxicity and enhanced bioactivity of cationic antimicrobial peptides liposomes in cell cultures and 3D epidermis model against HSV.
Sapir Ron-Doitch (2016)
Membrane interactions of mesoporous silica nanoparticles as carriers of antimicrobial peptides.
Katharina Braun (2016)
Antimicrobial and Immunomodulatory Activities of PR-39 Derived Peptides
E. Veldhuizen (2014)
Y. Chen (2014)
Antimicrobial peptides on calcium phosphate-coated titanium for the prevention of implant-associated infections.
Mehdi Kazemzadeh-Narbat (2010)
Celecoxib-loaded liposomes: effect of cholesterol on encapsulation and in vitro release characteristics.
Asli Deniz (2010)
Nanomechanical mapping of bone tissue regenerated by magnetic scaffolds
M. Bianchi (2015)
Stability of Antimicrobial Decapeptide (KSL) and Its Analogues for Delivery in the Oral Cavity
Dong Hee Na (2007)
M. Vaaraand (1996)
Efficacy of the Novel Topical Antimicrobial Agent PXL150 in a Mouse Model of Surgical Site Infections
J. Håkansson (2014)
Design and Characterization of a Novel p1025 Peptide-Loaded Liquid Crystalline System for the Treatment of Dental Caries
G. Calixto (2016)
Adsorption of nisin and pediocin on nanoclays.
S. M. M. Meira (2015)
The consideration of indolicidin modification to balance its hemocompatibility and delivery efficiency.
C. Tsai (2015)
Antimicrobial properties of liposomal polymyxin B.
S. McAllister (1999)
Delivery of LLKKK18 loaded into self-assembling hyaluronic acid nanogel for tuberculosis treatment.
J. Silva (2016)
Synergistic Anti-Inflammatory Activity of the Antimicrobial Peptides Human Beta-Defensin-3 (hBD-3) and Cathelicidin (LL-37) in a Three-Dimensional Co-Culture Model of Gingival Epithelial Cells and Fibroblasts
Telma Blanca Lombardo Bedran (2014)
Molecular electroporation: a unifying concept for the description of membrane pore formation by antibacterial peptides, exemplified with NK‐lysin
Maria Miteva (1999)
Membrane thinning due to antimicrobial peptide binding: an atomic force microscopy study of MSI-78 in lipid bilayers.
A. Mecke (2005)
Inorganic nanomaterials as delivery systems for proteins, peptides, DNA, and siRNA
M. Malmsten (2013)
Surface Engineering of Liposomes for Stealth Behavior
Okhil K Nag (2013)
Polymeric Systems of Antimicrobial Peptides—Strategies and Potential Applications
M. Sobczak (2013)
R. V. Petersen (1985)
Geometry and surface characteristics of gold nanoparticles influence their biodistribution and uptake by macrophages.
Melittin-lipid interaction: a comparative study using liposomes, micelles and bilayer disks.
A. Lundquist (2008)
Bolaamphiphile-based nanocomplex delivery of phosphorothioate gapmer antisense oligonucleotides as a treatment for Clostridium difficile
J. Hegarty (2016)
Challenges and future prospects of antibiotic therapy: from peptides to phages utilization
Santi M. Mandal (2014)
Drug release and bone growth studies of antimicrobial peptide-loaded calcium phosphate coating on titanium.
Mehdi Kazemzadeh-Narbat (2012)
Electrically gated ionic channels in lipid bilayers.
G. Ehrenstein (1977)
Bioactivity of WLBU2 peptide antibiotic in combination with bioerodible polymer.
J. McClanahan (2011)
Covalent immobilization of antimicrobial peptides (AMPs) onto biomaterial surfaces.
Fabíola Costa (2011)
Polymeric Delivery Systems, Gordon and Breach Science Publishers, New York
H. Ringsdorf (1978)
Incorporation of antimicrobial compounds in mesoporous silica film monolith.
I. Izquierdo-Barba (2009)
Conjugation of Polyphosphoester and Antimicrobial Peptide for Enhanced Bactericidal Activity and Biocompatibility.
Dicky Pranantyo (2016)
Development and In Vivo Evaluation of a Novel Histatin-5 Bioadhesive Hydrogel Formulation against Oral Candidiasis
Eric F Kong (2015)
Cationic Antimicrobial Peptides Cytotoxicity on Mammalian Cells: An Analysis Using Therapeutic Index Integrative Concept
M. Bacalum (2014)
Development of an anti-microbial peptide-mediated liposomal delivery system: a novel approach towards pH-responsive anti-microbial peptides
Q. Zhang (2016)
Translocation of a channel-forming antimicrobial peptide, magainin 2, across lipid bilayers by forming a pore.
K. Matsuzaki (1995)
Cell-Penetrating Antimicrobial Peptides – Prospectives for Targeting Intracellular Infections
J. S. Bahnsen (2014)
Biodegradable macromolecular conjugates of citropin: Synthesis, characterization and in vitro efficiency study
M. Sobczak (2014)
H. Machado (2013)
Characterization and potential applications of nanostructured aqueous dispersions.
A. Yaghmur (2009)
Antimicrobial activities of amphiphilic peptides covalently bonded to a water-insoluble resin.
S. Haynie (1995)
Antimicrobial and cell-penetrating properties of penetratin analogs: effect of sequence and secondary structure.
J. S. Bahnsen (2013)
Lipid-Based Liquid Crystals As Carriers for Antimicrobial Peptides: Phase Behavior and Antimicrobial Effect.
Lukas Boge (2016)
Alpha-helical antimicrobial peptides--using a sequence template to guide structure-activity relationship studies.
I. Zelezetsky (2006)
Functional synergism of the magainins PGLa and magainin-2 in Escherichia coli, tumor cells and liposomes.
H. Westerhoff (1995)
Intermolecular interactions between salmon calcitonin, hyaluronate, and chitosan and their impact on the process of formation and properties of peptide-loaded nanoparticles.
A. Umerska (2014)
Liposomal (MLV) polymyxin B: physicochemical characterization and effect of surface charge and drug association.
S. M. Lawrence (1993)
C-terminal domain of human CAP18 antimicrobial peptide induces apoptosis in oral squamous cell carcinoma SAS-H1 cells.
Kazuhiko Okumura (2004)
Nanoencapsulation I. Methods for preparation of drug-loaded polymeric nanoparticles.
C. Reis (2006)
Cholesterol reduces pardaxin's dynamics-a barrel-stave mechanism of membrane disruption investigated by solid-state NMR.
A. Ramamoorthy (2010)
Biodegradable Drug Delivery Systems Based on Polypeptides
Robert V. Petersen (1985)
Functionalized micellar assemblies prepared via block copolymers synthesized by living free radical polymerization upon peptide-loaded resins.
M. Becker (2005)
T. Ebenhan (2014)
Kinetics of Dye Efflux and Lipid Flip-Flop Induced by δ-Lysin in Phosphatidylcholine Vesicles and the Mechanism of Graded Release by Amphipathic, α-Helical Peptides†
A. Pokorny (2004)
Polymeric Delivery Systems
R. Langer (1990)
In-vitro activity of cationic peptides alone and in combination with clinically used antimicrobial agents against Pseudomonas aeruginosa.
A. Giacometti (1999)
An antimicrobial peptide, magainin 2, induced rapid flip-flop of phospholipids coupled with pore formation and peptide translocation.
K. Matsuzaki (1996)
In vivo release of the antimicrobial peptide hLF1‐11 from calcium phosphate cement
Hein P. Stallmann (2008)
Liposomal entrapment of the neutrophil-derived peptide indolicidin endows it with in vivo antifungal activity.
I. Ahmad (1995)
Membrane pores induced by magainin.
S. Ludtke (1996)
Antimicrobial Peptides for Therapeutic Applications: A Review
Min-duk Seo (2012)
Chewing gum as a drug delivery system
M. Rassing (1994)
Novel Formulations for Antimicrobial Peptides
A. M. Carmona-Ribeiro (2014)
Serum Stabilities of Short Tryptophan- and Arginine-Rich Antimicrobial Peptide Analogs
L. T. Nguyen (2010)
Liposomes as nanomedical devices
G. Bozzuto (2015)
Factors affecting microencapsulation of drugs in liposomes.
S. B. Kulkarni (1995)
Effect of polyplex morphology on cellular uptake, intracellular trafficking, and transgene expression.
Julie Shi (2013)
Antimicrobial Peptides and Innate Immunity
P. Hiemstra (2013)
Synthesis and antibacterial activity of nisin-containing block copolymers.
P. Joshi (2009)
Enzymatic Polymerization of Cyclic Monomers in Ionic Liquids as a Prospective Synthesis Method for Polyesters Used in Drug Delivery Systems
U. Piotrowska (2014)
Translocating proline-rich peptides from the antimicrobial peptide bactenecin 7.
Kristen Sadler (2002)
Efficient delivery of cyclic peptides into mammalian cells with short sequence motifs.
Ziqing Qian (2013)
Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?
K. Brogden (2005)
Controlled alteration of the shape and conformational stability of alpha-helical cell-lytic peptides: effect on mode of action and cell specificity.
I. Zelezetsky (2005)
Cytotoxicity and apoptosis mediated by two peptides of innate immunity.
A. Risso (1998)
Crotamine is a novel cell‐penetrating protein from the venom of rattlesnake Crotalus durissus terrificus
A. Kerkis (2004)
Improved methods for classification, prediction, and design of antimicrobial peptides.
G. Wang (2015)
Application of Nanotechnology in Drug Delivery
J. Silva (2014)
Role of lipids in the interaction of antimicrobial peptides with membranes.
Vitor Teixeira (2012)
Continuous-release or burst-release of the antimicrobial peptide human lactoferrin 1-11 (hLF1-11) from calcium phosphate bone substitutes.
H. P. Stallmann (2003)
Control of cell selectivity of antimicrobial peptides.
K. Matsuzaki (2009)
A Cell-penetrating Peptide Derived from Human Lactoferrin with Conformation-dependent Uptake Efficiency
Falk Duchardt (2009)
The Human Antimicrobial Peptide LL-37 Transfers Extracellular DNA Plasmid to the Nuclear Compartment of Mammalian Cells via Lipid Rafts and Proteoglycan-dependent Endocytosis*
S. Sandgren (2004)
Antibiofilm and Antimicrobial Efficacy of DispersinB®-KSL-W Peptide-Based Wound Gel Against Chronic Wound Infection Associated Bacteria
P. V. Gawande (2014)
PEG-stabilized lipid disks as carriers for amphiphilic antimicrobial peptides.
M. Zetterberg (2011)
Optimization of the antimicrobial activity of magainin peptides by modification of charge
M. Dathe (2001)
Peptide KSL-W-Loaded Mucoadhesive Liquid Crystalline Vehicle as an Alternative Treatment for Multispecies Oral Biofilm
J. Bernegossi (2015)
Chewing gum of antimicrobial decapeptide (KSL) as a sustained antiplaque agent: preformulation study.
D. Na (2005)
Synergistic Effects of Antimicrobial Peptides and Antibiotics against Clostridium difficile
S. Nuding (2014)
Peptide Antimicrobial Agents
H. Jenssen (2006)
Potential benefits of chewing gum for the delivery of oral therapeutics and its possible role in oral healthcare
S. Wessel (2016)
Marine antimicrobial peptide tachyplesin as an efficient nanocarrier for macromolecule delivery in plant and mammalian cells
A. Jain (2015)
Cationic amphipathic histidine-rich peptides for gene delivery.
A. Kichler (2006)
Hydrophobicity, hydrophobic moment and angle subtended by charged residues modulate antibacterial and haemolytic activity of amphipathic helical peptides
M. Dathe (1997)
In Vitro Activities of Polycationic Peptides Alone and in Combination with Clinically Used Antimicrobial Agents againstRhodococcus equi
A. Giacometti (1999)
Synergistic Interactions between Mammalian Antimicrobial Defense Peptides
H. Yan (2001)
Stealth liposomes: review of the basic science, rationale, and clinical applications, existing and potential
M. Immordino (2006)
An insect antibacterial peptide-based drug delivery system.
L. Otvos (2004)
Antimicrobial Peptide-Driven Colloidal Transformations in Liquid-Crystalline Nanocarriers.
M. Gontsarik (2016)
An electrochemical study into the interaction between complement-derived peptides and DOPC mono- and bilayers.
L. Ringstad (2008)
Structure and properties of pharmacologically active polymers
H. Ringsdorf (2007)
Antibacterial Peptide Nucleic Acid-Antimicrobial Peptide (PNA-AMP) Conjugates: Antisense Targeting of Fatty Acid Biosynthesis.
A. M. Hansen (2016)
Strategies in the design of nanoparticles for therapeutic applications
Robby A. Petros (2010)
Controlling molecular transport and sustained drug release in lipid-based liquid crystalline mesophases.
Alexandru Zabara (2014)
Release of a Wound-Healing Agent from PLGA Microspheres in a Thermosensitive Gel
H. A. Machado (2013)
Synthetic DNA delivery systems
D. Luo (2000)
Effect of α-helical peptides on liposome structure: a comparative study of melittin and alamethicin.
P. Wessman (2010)
Antimicrobial Peptides for Plaque Control
K. Leung (2009)
Enhanced activity of liposomal polymyxin B against Pseudomonas aeruginosa in a rat model of lung infection.
Abdelwahab Omri (2002)
Design and mechanism of action of a novel bacteria-selective antimicrobial peptide from the cell-penetrating peptide Pep-1.
W. Zhu (2006)
Interaction of gramicidin with DPPC/DODAB bilayer fragments.
C. A. Carvalho (2012)
Identification of a novel lytic peptide for the treatment of solid tumours
C. Szczepanski (2014)
Antitumor activity of the antimicrobial peptide magainin II against bladder cancer cell lines.
J. Lehmann (2006)
Non-Membrane Permeabilizing Modes of Action of Antimicrobial Peptides on Bacteria.
M. Scocchi (2016)
'Detergent-like' permeabilization of anionic lipid vesicles by melittin.
A. S. Ladokhin (2001)
The mechanisms of drug release in poly(lactic-co-glycolic acid)-based drug delivery systems--a review.
S. Fredenberg (2011)
Adsorption of proteins and nucleic acids on clay minerals and their interactions: A review
W. Yu (2013)
Size, stability, and entrapment efficiency of phospholipid nanocapsules containing polypeptide antimicrobials.
L. Were (2003)
Studies on anticancer activities of antimicrobial peptides.
D. Hoskin (2008)
Surface active drugs: self-association and interaction with membranes and surfactants. Physicochemical and biological aspects.
S. Schreier (2000)
Science Against Pathogens: Communicating Current Research and Technological Advances
C. Cézard (2011)
Antimicrobial peptides: general overview and clinical implications in human health and disease.
Eduardo Guaní-Guerra (2010)
Characterization, stability and in vivo targeting of liposomal formulations containing cyclosporin
A. Al-Angary (1995)
Roles of Hydrophobicity and Charge Distribution of Cationic Antimicrobial Peptides in Peptide-Membrane Interactions*
Lois M. Yin (2012)
Interaction of antimicrobial dermaseptin and its fluorescently labeled analogues with phospholipid membranes.
Y. Pouny (1992)
Cationic bactericidal peptides.
R. Hancock (1995)
Intracellular Toxicity of Proline-Rich Antimicrobial Peptides Shuttled into Mammalian Cells by the Cell-Penetrating Peptide Penetratin
A. Hansen (2012)
An antimicrobial peptide with angiogenic properties, AG-30/5C, activates human mast cells through the MAPK and NF-κB pathways
Kazo Kanazawa (2016)
Rational Design of α-Helical Antimicrobial Peptides with Enhanced Activities and Specificity/Therapeutic Index*
Yuxin Chen (2005)
Antimicrobial Peptides: Versatile Biological Properties
M. Pushpanathan (2013)
B. Fang (2013)
Influences on the antimicrobial activity of surface-adsorbed nisin
CK Bower (2005)
Interaction of an artificial antimicrobial peptide with lipid membranes.
Lanlan Yu (2009)
In Vitro Activity and Killing Effect of Citropin 1.1 against Gram-Positive Pathogens Causing Skin and Soft Tissue Infections
A. Giacometti (2005)
Peptide and Protein Interaction with Membrane Systems: Applications to Antimicrobial Therapy and Protein Drug Delivery
S. Bobone (2014)
Conjugation of photosensitisers to antimicrobial peptides increases the efficiency of photodynamic therapy in cancer cells.
F. Moret (2015)
A common landscape for membrane‐active peptides
Nicholas B Last (2013)
Cubic and Hexagonal Liquid Crystals as Drug Delivery Systems
Y. Chen (2014)
How to cite this article: Piotrowska U, Sobczak M, Oledzka E. Current state of a dual behaviour of antimicrobial peptides-Therapeutic agents and promising delivery vectors
C Rosés (2012)
Antitumor effects and cell selectivity of temporin-1CEa, an antimicrobial peptide from the skin secretions of the Chinese brown frog (Rana chensinensis).
Che Wang (2012)
Designing carbohydrate nanoparticles for prolonged efficacy of antimicrobial peptide.
L. Bi (2011)
Nanotools for the delivery of antimicrobial peptides.
Patricia Urban (2012)
Self-assembled hyaluronate/protamine polyelectrolyte nanoplexes: synthesis, stability, biocompatibility and potential use as peptide carriers.
A. Umerska (2014)
Interaction of melittin with membrane cholesterol: a fluorescence approach.
H. Raghuraman (2004)
Effect of the antimicrobial decapeptide KSL on the growth of oral pathogens and Streptococcus mutans biofilm.
Y. Liu (2011)
Current state of a dual behaviour of antimicrobial peptides—Therapeutic agents and promising delivery vectors
U Piotrowska (2012)
Lipid-based nanoformulations for peptide delivery.
N. Matougui (2016)
Short AntiMicrobial Peptides (SAMPs) as a class of extraordinary promising therapeutic agents
S. Ramesh (2016)
Convenient Preparation of Bactericidal Hydrogels by Covalent Attachment of Stabilized Antimicrobial Peptides Using Thiol–ene Click Chemistry
Rik T. C. Cleophas (2014)
nNOS inhibition, antimicrobial and anticancer activity of the amphibian skin peptide, citropin 1.1 and synthetic modifications. The solution structure of a modified citropin 1.1.
Jason R. Doyle (2003)
Determination of stereochemistry stability coefficients of amino acid side-chains in an amphipathic alpha-helix.
Y. Chen (2002)
Cell-penetrating γ-peptide/antimicrobial undecapeptide conjugates with anticancer activity
Cristina Rosés (2012)
In vitro activity of citropin 1.1 alone and in combination with clinically used antimicrobial agents against Rhodococcus equi.
A. Giacometti (2005)
Antimicrobial effectiveness of liposomal polymyxin B against resistant Gram-negative bacterial strains.
M. Alipour (2008)
Mechanism of synergism between antimicrobial peptides magainin 2 and PGLa.
K. Matsuzaki (1998)
Understanding the adsorption of salmon calcitonin, antimicrobial peptide AP114 and polymyxin B onto lipid nanocapsules.
A. Umerska (2016)
Integration of antimicrobial peptides with gold nanoparticles as unique non-viral vectors for gene delivery to mesenchymal stem cells with antibacterial activity.
L. Peng (2016)
Novel gramicidin formulations in cationic lipid as broad-spectrum microbicidal agents
Danielle Amt Ragioto (2014)
Sustained-release drug delivery of antimicrobials in controlling of supragingival oral biofilms
D. Steinberg (2017)
Targeted Antimicrobial Peptides
M. Devocelle (2012)
Antimicrobial Peptides: Their Role as Infection-Selective Tracers for Molecular Imaging
T. Ebenhan (2014)
Structural determinants of host defense peptides for antimicrobial activity and target cell selectivity.
D. Takahashi (2010)
Suppression of Listeria monocytogenes colonization following adsorption of nisin onto silica surfaces.
C. K. Bower (1995)
Antimicrobial peptides with cell-penetrating peptide properties and vice versa
Katrin Splith (2011)
A novel application of indolicidin for gene delivery.
Wei-Wen Hu (2013)
PEGylation of the antimicrobial peptide nisin A: problems and perspectives.
A. Guiotto (2003)
Permeabilization of raft-containing lipid vesicles by delta-lysin: a mechanism for cell sensitivity to cytotoxic peptides.
A. Pokorny (2005)
M. Pushpanathan (2013)
RGD-modified lipid disks as drug carriers for tumor targeted drug delivery.
Jie Gao (2016)
Role of membranes in the activities of antimicrobial cationic peptides.
R. Hancock (2002)
Diffusion of univalent ions across the lamellae of swollen phospholipids.
A. Bangham (1965)
Antimicrobial activity, improved cell selectivity and mode of action of short PMAP-36-derived peptides against bacteria and Candida
Yinfeng Lyu (2016)
Novel Antimicrobial Peptides with High Anticancer Activity and Selectivity
Hung-Lun Chu (2015)
This paper is referenced by
Reverse micelle-lipid nanocapsules: a novel strategy for drug delivery of the plectasin derivate AP138 antimicrobial peptide
Anne-Claire Groo (2018)
Drug delivery systems designed to overcome antimicrobial resistance
Thanh-Nhat Pham (2019)
Topological Aspects of the Design of Nanocarriers for Therapeutic Peptides and Proteins
Nadezhda Knauer (2019)
A Novel Delivery System for the Controlled Release~of Antimicrobial Peptides: Citropin 1.1 and Temporin A
U. Piotrowska (2018)
Figainin 1, a Novel Amphibian Skin Peptide with Antimicrobial and Antiproliferative Properties
Carlos José Correia Santana (2020)
Evaluation du potentiel thérapeutique d'un mannodendrimère anti-inflammatoire dans un modèle murin d'infection par Francisella tularensis
C. Robert (2017)
Antimicrobial host defence peptides: functions and clinical potential
N. Mookherjee (2020)
Self-Assembled Antimicrobial Nanomaterials
A. M. Carmona-Ribeiro (2018)
Innate Inspiration: Antifungal Peptides and Other Immunotherapeutics From the Host Immune Response
D. Mercer (2020)
Sustained Release of Antimicrobial Peptide from Self-Assembling Hydrogel Enhanced Osteogenesis
Guoli Yang (2018)
Interdependence of charge and secondary structure on cellular uptake of cell penetrating peptide functionalized silica nanoparticles
Isabel Gessner (2020)
[Monoclonal spread of multi-drug resistant CTX-M-15-producing Klebsiella pneumoniae. Impact of measures to control the outbreak].
M. A. Asencio Egea (2018)
Insights on the structure‐activity relationship of peptides derived from Sticholysin II
Aline Lima de Oliveira (2018)
Utilizing Organoid and Air-Liquid Interface Models as a Screening Method in the Development of New Host Defense Peptides
K. Choi (2020)
Role of Cationic Side Chains in the Antimicrobial Activity of C18G
Eric M Kohn (2018)
The conjugation of indolicidin to polyethylenimine for enhanced gene delivery with reduced cytotoxicity.
Wei-Wen Hu (2018)
Integration of antimicrobial peptides and gold nanorods for bimodal antibacterial applications.
J. Chen (2020)
A comparison of different strategies for antimicrobial peptides incorporation onto/into lipid nanocapsules.
N. Matougui (2019)
Diseminación monoclonal de Klebsiella pneumoniae productora de CTX-M-15 multirresistente. Impacto de las medidas para controlar el brote
María Ángeles Asencio Egea (2018)
Antimicrobial Peptides as Anticancer Agents: Functional Properties and Biological Activities
Anna Lucia Tornesello (2020)
The Road from Host-Defense Peptides to a New Generation of Antimicrobial Drugs
A. Boto (2018)
The Effect of Polymer Microstructure on Encapsulation Efficiency and Release Kinetics of Citropin 1.1 from the Poly(ε-caprolactone) Microparticles
U. Piotrowska (2018)
Antimicrobial and Cell-Penetrating Peptides: How to Understand Two Distinct Functions Despite Similar Physicochemical Properties.
I. Neundorf (2019)
The Amphibian Antimicrobial Peptide Temporin B Inhibits In Vitro Herpes Simplex Virus 1 Infection
M. Marcocci (2018)
Humoral Innate Immune Effector Responses
W. Land (2018)
Antimicrobial Peptides as Probes in Biosensors Detecting Whole Bacteria: A Review
Éric Pardoux (2020)
Formulation technologies and advances for oral delivery of novel nitroimidazoles and antimicrobial peptides.
John Ndayishimiye (2020)