Online citations, reference lists, and bibliographies.
← Back to Search

Expression Of Enamel Proteins And LEF1 In Adamantinomatous Craniopharyngioma: Evidence For Its Odontogenic Epithelial Differentiation

S. Sekine, T. Takata, T. Shibata, M. Mori, Y. Morishita, M. Noguchi, T. Uchida, Y. Kanai, S. Hirohashi
Published 2004 · Biology, Medicine

Cite This
Download PDF
Analyze on Scholarcy
Share
Aims:  Adamantinomatous craniopharyngioma (ACP) resembles histologically some odontogenic tumours, such as ameloblastoma and calcifying odontogenic cyst. However, there has been no evidence that ACP differentiates also functionally as odontogenic epithelium. The aim of this study was to gain evidence of odontogenic epithelial differentiation in ACP by means of immunohistochemistry. Among normal human tissues, enamel proteins are expressed exclusively in teeth, and lymphoid enhancer factor 1 (LEF1), in co‐operation with β‐catenin, play an important role in tooth development. The expression of these proteins is therefore indicative of odontogenic epithelial differentiation.
This paper references
Craniopharyngiomas (pituitary adamantinomas)
JG Love (1950)
Calcifying odontogenic cyst. A review of ninety-two cases with reevaluation of their nature as cysts or neoplasms, the nature of ghost cells, and subclassification. Oral Surg
S P Hong (1991)
FGF 4 , a direct target of LEF 1 and Wnt signaling , can rescue the arrest of tooth organogenesis in Lef 1 ( - ⁄ - ) mice
Galceran J Kratochwil K (2002)
10.3109/03008209609029183
Vertebrate mineralized matrix proteins: structure and function.
P. Robey (1996)
10.1038/nature01458
Links between signal transduction, transcription and adhesion in epithelial bud development
C. Jamora (2003)
10.1101/GAD.10.11.1382
Lef1 expression is activated by BMP-4 and regulates inductive tissue interactions in tooth and hair development.
K. Kratochwil (1996)
10.1007/BF00698663
The development and morphogenesis of the human pituitary gland
H. Ikeda (2004)
Craniofacial development, in mouse development
MJ Depew (2002)
10.1007/s004410051123
Immunocytochemical and immunochemical study of enamelins, using antibodies against porcine 89-kDa enamelin and its N-terminal synthetic peptide, in porcine tooth germs
N. Dohi (1998)
10.1038/382638A0
Functional interaction of β-catenin with the transcription factor LEF-1
J. Behrens (1996)
10.1016/0925-4773(96)00597-7
Nuclear localization of β-catenin by interaction with transcription factor LEF-1
O. Huber (1996)
10.1002/1097-0142(197202)29:2<423::AID-CNCR2820290225>3.0.CO;2-X
Pituitary craniopharyngioma with tooth formation
T. Seemayer (1972)
10.1016/B978-012597951-1/50023-8
19 – Craniofacial Development
M. Depew (2002)
10.1016/S0002-9440(10)64477-X
Short Communication Craniopharyngiomas of Adamantinomatous Type Harbor -Catenin Gene Mutations
S. Sekine (2002)
10.1016/0030-4220(83)90098-1
The histologic similarity between craniopharyngioma and odontogenic lesions: a reappraisal.
M. Bernstein (1983)
Craniopharyngiomas of adamantinomatous type harbor beta-catenin gene mutations.
S. Sekine (2002)
10.1101/GAD.1035602
FGF4, a direct target of LEF1 and Wnt signaling, can rescue the arrest of tooth organogenesis in Lef1(-/-) mice.
K. Kratochwil (2002)
Ten Have-Opbroek AA. Expression of Tcf ⁄ Lef and sFrp and localization of b-catenin in the developing mouse lung
M Tebar (2001)
10.1016/S0945-053X(01)00155-X
Is there more to enamel matrix proteins than biomineralization?
M. Zeichner-David (2001)
10.1046/j.1365-2559.1997.d01-584.x
Odontogenic classification of craniopharyngiomas: a clinicopathological study of 54 cases
W. Paulus (1997)
10.1023/A:1004051017425
Ghost Cells in Calcifying Odontogenic Cyst Express Enamel-related Proteins
T. Takata (2004)
10.1007/s004180050136
Immunochemical and immunohistochemical study of the 27- and 29-kDa calcium-binding proteins and related proteins in the porcine tooth germ
C. Murakami (1997)
10.1016/S0925-4773(01)00556-1
Expression of Tcf/Lef and sFrp and localization of β-catenin in the developing mouse lung
M. Tebar (2001)
10.1016/0030-4220(91)90190-N
Calcifying odontogenic cyst. A review of ninety-two cases with reevaluation of their nature as cysts or neoplasms, the nature of ghost cells, and subclassification.
S. Hong (1991)
10.1111/J.1600-0714.1992.TB00993.X
Immunohistochemical demonstration of enamel proteins in odontogenic tumors.
T. Saku (1992)
10.1021/BI972120Y
Identification and structural and functional characterization of human enamelysin (MMP-20).
E. Llano (1997)
10.1016/0030-4220(59)90144-6
The ameloblastoma and the craniopharyngioma; their similarities and differences.
R. Gorlin (1959)
10.1016/S0002-9440(10)63528-6
Beta-catenin mutations are frequent in calcifying odontogenic cysts, but rare in ameloblastomas.
S. Sekine (2003)
10.1177/00220345000790081401
Immunohistochemical Detection and Distribution of Enamelysin (MMP-20) in Human Odontogenic Tumors
T. Takata (2000)
10.1111/J.1600-0722.1998.TB02188.X
The developing enamel matrix: nature and function.
C. Robinson (1998)
and differentiation
C Jamora (1999)
Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation.
R. Dasgupta (1999)
10.1097/00000478-200303000-00011
Clinicopathologic Spectrum of the So-Called Calcifying Odontogenic Cysts: A Study of 21 Intraosseous Cases With Reconsideration of the Terminology and Classification
T. Li (2003)
10.3171/JNS.1981.55.5.0832
Successful surgical treatment of an odontogenic ossified craniopharyngioma. Case report.
J. A. Alvarez-Garijo (1981)



This paper is referenced by
10.1111/his.12071
Does the calcification of adamantinomatous craniopharyngioma resemble the calcium deposition of osteogenesis/odontogenesis?
Q. Song-tao (2014)
10.1007/s00401-006-0184-3
Nuclear β-catenin accumulation associates with epithelial morphogenesis in craniopharyngiomas
R. Buslei (2006)
10.3353/OMP.13.7
Expression of hard α-keratins in adenomatoid odontogenic tumor: a case study with immunohistochemical analysis
Kentaro Kikuchi (2008)
10.1016/B978-0-12-416706-3.00004-0
Craniopharyngioma: Embryology, Pathology, and Molecular Aspects
Anthony T. Yachnis (2015)
10.1111/nan.12226
Molecular and cellular pathogenesis of adamantinomatous craniopharyngioma
J. P. Martinez-Barbera (2015)
10.1186/s40478-016-0287-6
Adamantinomatous and papillary craniopharyngiomas are characterized by distinct epigenomic as well as mutational and transcriptomic profiles
A. Hoelsken (2016)
10.1210/jc.2019-01299
The Medical Therapy of Craniopharyngiomas: The Way Ahead.
K. Alexandraki (2019)
10.1210/en.2018-00563
Regulation of Pituitary Progenitor Differentiation by &bgr;-Catenin
Julie L Youngblood (2018)
Introduction to Neoplasm : ‘ Tumor Classification ’ A
Joshi (2013)
Immunohistochemical Analysis of Metalloproteases in Dentigerous Cysts, Radicular Cysts and Keratocystic Odontogenic Tumors: Systematic Review
R. Scariot (2012)
10.1111/j.1750-3639.2008.00180.x
Target Gene Activation of the Wnt Signaling Pathway in Nuclear β‐Catenin Accumulating Cells of Adamantinomatous Craniopharyngiomas
A. Hoelsken (2009)
10.1080/17446651.2020.1770081
Craniopharyngioma treatment: an updated summary of important clinicopathological concepts
R. Prieto (2020)
10.12659/MSM.896221
Evaluation of Macular Ganglion Cell Complex and Peripapillary Retinal Nerve Fiber Layer in Primary Craniopharyngioma by Fourier-Domain Optical Coherence Tomography
L. Yang (2016)
10.1043/1543-2165(2008)132[500:TDDOCN]2.0.CO;2
The differential diagnosis of central nervous system tumors: a critical examination of some recent immunohistochemical applications.
M. Edgar (2008)
10.1007/978-3-319-51890-9_2
Transcriptomic and Genomic Analyses of Human Craniopharyngioma
Leslie E Robinson (2017)
10.1007/s00401-005-0009-9
Abundant hypermethylation of SOCS-1 in clinically silent pituitary adenomas
R. Buslei (2005)
10.1016/B978-0-12-416706-3.00032-5
Malignant Transformation of Craniopharyngioma
Jiang Qian (2015)
10.1007/s11102-018-0890-6
Can tissue biomarkers reliably predict the biological behavior of craniopharyngiomas? A comprehensive overview
R. Prieto (2018)
10.1007/978-3-030-11339-1_3
Adamantinomatous Craniopharyngioma: Genomics, Radiologic Findings, Clinical, and Prognosis
H. Müller (2019)
10.3233/CBM-161576
Osteoblastic differentiation and cell calcification of adamantinomatous craniopharyngioma induced by bone morphogenetic protein-2.
Xiaorong Yan (2017)
10.1007/978-3-030-41176-3
Adult Craniopharyngiomas: Differences and Lessons from Paediatrics
Emmanuel Jouanneau (2020)
10.4132/KoreanJPathol.2013.47.3.191
Current Concepts and Occurrence of Epithelial Odontogenic Tumors: I. Ameloblastoma and Adenomatoid Odontogenic Tumor
S. Lee (2013)
10.1111/bpa.12499
Models of human adamantinomatous craniopharyngioma tissue: Steps toward an effective adjuvant treatment
A. Hoelsken (2017)
10.1007/s00401-010-0642-9
Tumour cell migration in adamantinomatous craniopharyngiomas is promoted by activated Wnt-signalling
A. Hoelsken (2010)
10.1007/s00428-018-2323-3
Molecular defects in BRAF wild-type ameloblastomas and craniopharyngiomas—differences in mutation profiles in epithelial-derived oropharyngeal neoplasms
S. Bartels (2018)
10.1016/j.jnci.2015.06.003
Comparative immunohistochemical expression of β-catenin, EGFR, ErbB2, and p63 in adamantinomatous and papillary craniopharyngiomas.
Ghada E. Esheba (2015)
10.1159/000442992
Unicystic Ameloblastomatoid Cystic Craniopharyngioma: Pathological Discussion and Clinical Significance of Cyst Formation in Adamantinomatous Craniopharyngioma
Tomu Okada (2016)
10.1097/PAS.0b013e31802d8a96
The Spectrum of Malignancy in Craniopharyngioma
F. Rodriguez (2007)
10.1016/j.clineuro.2015.08.015
Calretinin is expressed in the stroma of adamantinomatous craniopharyngioma and may induce calcification
Wang Chao-hu (2015)
10.1007/s12022-014-9341-8
The Wnt Signalling Cascade and the Adherens Junction Complex in Craniopharyngioma Tumorigenesis
V. Preda (2014)
10.1002/dc.23820
LEF‐1: Diagnostic utility in distinguishing basaloid neoplasms of the salivary gland
A. Schmitt (2017)
10.1111/J.1600-0714.2007.00550.X
Presence of ghost cells and the Wnt signaling pathway in odontomas.
A. Tanaka (2007)
See more
Semantic Scholar Logo Some data provided by SemanticScholar