← Back to Search
Devil Inside: Does Plant Programmed Cell Death Involve The Endomembrane System?
Published 2010 · Medicine, Biology
Download PDFAnalyze on Scholarcy
Eukaryotic cells have to constantly cope with environmental cues and integrate developmental signals. Cell survival or death is the only possible outcome. In the field of animal biology, tremendous efforts have been put into the understanding of mechanisms underlying cell fate decision. Distinct organelles have been proven to sense a broad range of stimuli and, if necessary, engage cell death signalling pathway(s). Over the years, forward and reverse genetic screens have uncovered numerous regulators of programmed cell death (PCD) in plants. However, to date, molecular networks are far from being deciphered and, apart from the autophagic compartment, no organelles have been assigned a clear role in the regulation of cellular suicide. The endomembrane system (ES) seems, nevertheless, to harbour a significant number of cell death mediators. In this review, the involvement of this system in the control of plant PCD is discussed in-depth, as well as compared and contrasted with what is known in animal and yeast systems.
This paper references
Endoplasmic reticulum stress and apoptosis
J. Faitová (2006)
DCD – a novel plant
R. Tenhaken (2005)
Tomato Phospholipid Hydroperoxide Glutathione Peroxidase Inhibits Cell Death Induced by Bax and Oxidative Stresses in Yeast and Plants1
S. Chen (2004)
A homolog of the defender against apoptotic death gene (DAD1) in senescing gladiolus petals is down-regulated prior to the onset of programmed cell death.
Tetsuya Yamada (2004)
Oxylipin Profiling of the Hypersensitive Response in Arabidopsis thaliana
M. Andersson (2006)
An evolving view of the eukaryotic oligosaccharyltransferase.
D. Kelleher (2006)
Autophagy Genes Are Essential for Dauer Development and Life-Span Extension in C. elegans
A. Meléndez (2003)
AtATG18a is required for the formation of autophagosomes during nutrient stress and senescence in Arabidopsis thaliana.
Y. Xiong (2005)
Bax inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast.
Q. Xu (1998)
Autophagy: an ER Protein Quality Control Process
K. Kruse (2006)
Identification of a novel conserved human gene, TEGT.
L. Walter (1995)
Assortment of phosphatidylinositol 3-kinase complexes--Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiae.
K. Obara (2006)
Cellular response to unfolded proteins in the endoplasmic reticulum of plants
R. Urade (2007)
The morphology of various types of cell death in prenatal tissues.
J. Schweichel (1973)
What Is Moving in the Secretory Pathway of Plants?1
E. Rojo (2008)
Paradigms of programmed cell death in animals and plants
M. B. Dickman (2004)
Arabidopsis AtBECLIN 1/AtAtg6/AtVps30 is essential for pollen germination and plant development
Genji Qin (2007)
Bax-induced cell death in tobacco is similar to the hypersensitive response.
C. Lacomme (1999)
Cell Death Suppressor Arabidopsis Bax Inhibitor-1 Is Associated with Calmodulin Binding and Ion Homeostasis1[OA]
Yuri Ihara-Ohori (2006)
Induction of Protein Secretory Pathway Is Required for Systemic Acquired Resistance
D. Wang (2005)
A homologue of the defender against the apoptotic death gene (dad1) in UV-exposed Chlamydomonas cells is downregulated with the onset of programmed cell death
Swati Moharikar (2007)
A Porphyrin Pathway Impairment Is Responsible for the Phenotype of a Dominant Disease Lesion Mimic Mutant of Maize
G. Hu (1998)
The pre-autophagosomal structure organized
Y. Ohsumi (2001)
Bcl-2 Antiapoptotic Proteins Inhibit Beclin 1-Dependent Autophagy
S. Pattingre (2005)
Physiological functions of Atg6/Beclin 1: a unique autophagy-related protein
Yang Cao (2007)
Chloroplast Signaling and LESION SIMULATING DISEASE1 Regulate Crosstalk between Light Acclimation and Immunity in Arabidopsis[W]
Per Mühlenbock (2008)
Yeast Cell Death Caused by Mutation of the OST2 Gene Encoding the ε-Subunit of Saccharomyces cerevisiae Oligosaccharyltransferase
M. Sugiura (2006)
VASCULAR ASSOCIATED DEATH1, a Novel GRAM Domain–Containing Protein, Is a Regulator of Cell Death and Defense Responses in Vascular Tissues
Séverine Lorrain (2004)
The Mitochondrion and Plant Programmed Cell Death
Mark Diamond (2007)
An alternative, nonapoptotic form of programmed cell death.
S. Sperandio (2000)
The mammalian endoplasmic reticulum as a sensor for cellular stress
Yanjun Ma (2002)
Glycosylation of phytepsin and expression of dad1, dad2 and ost1 during onset of cell death in germinating barley scutella
P. Lindholm (2000)
Tunicamycin and brefeldin a induce in plant cells a programmed cell death showing apoptotic features
P. Crosti (2007)
The ricinosomes of senescing plant tissue bud from the endoplasmic reticulum
M. Schmid (2001)
The Arabidopsis NPR1 Disease Resistance Protein Is a Novel Cofactor That Confers Redox Regulation of DNA Binding Activity to the Basic Domain/Leucine Zipper Transcription Factor TGA1 Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.012849.
C. Despres (2003)
BI-1 Regulates Endoplasmic Reticulum Ca2+ Homeostasis Downstream of Bcl-2 Family Proteins*
C. Xu (2008)
BAX Inhibitor-1 Modulates Endoplasmic Reticulum Stress-mediated Programmed Cell Death in Arabidopsis*
N. Watanabe (2008)
XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor
H. Yoshida (2001)
The ins and outs of sphingolipid synthesis.
A. Futerman (2005)
Autophagy in yeast: a review of the molecular machinery.
W. Huang (2002)
2005)Classification of cell death: recommendations of the Nomenclature
G. Kroemer (2005)
Apoptotic-like programmed cell death in plants.
Theresa J. Reape (2008)
Signal integration in the endoplasmic reticulum unfolded protein response
D. Ron (2007)
Signaling the Unfolded Protein Response from the Endoplasmic Reticulum*
K. Zhang (2004)
Many ways to exit? Cell death categories in plants.
W. G. van Doorn (2005)
Fragmentation of the Golgi Apparatus: An Early Apoptotic Event Independent of the Cytoskeleton
S. Mukherjee (2007)
Protein database searches for multiple alignments.
S. Altschul (1990)
An Endoplasmic Reticulum Stress Response in Arabidopsis Is Mediated by Proteolytic Processing and Nuclear Relocation of a Membrane-Associated Transcription Factor, bZIP28[W][OA]
J. Liu (2007)
A caspase cleavage fragment of p115 induces fragmentation of the Golgi apparatus and apoptosis
R. Chiu (2002)
Changes in gene expression during programmed cell death in tomato cell suspensions
F. Hoeberichts (2004)
A New Branch of Endoplasmic Reticulum Stress Signaling and the Osmotic Signal Converge on Plant-specific Asparagine-rich Proteins to Promote Cell Death*
M. D. L. Costa (2008)
death during the plant innate immune response
Overexpression of barley BAX inhibitor 1 induces breakdown of mlo-mediated penetration resistance to Blumeria graminis
R. Hückelhoven (2003)
The Involvement of Cysteine Proteases and Protease Inhibitor Genes in the Regulation of Programmed Cell Death in Plants
M. Solomon (1999)
Animal cell-death suppressors Bcl-xL and Ced-9 inhibit cell death in tobacco plants
I. Mitsuhara (1999)
Expression of antiapoptotic genes bcl-xL and ced-9 in tomato enhances tolerance to viral-induced necrosis and abiotic stress.
P. Xu (2004)
2004)VPEgamma exhibits a caspase-like activity that contributes to defense against pathogens
E. Rojo (1906)
Autophagy 2, 238–240
plasmic reticulum (2009)
EDR2 negatively regulates salicylic acid-based defenses and cell death during powdery mildew infections of Arabidopsis thaliana
S. Vorwerk (2006)
Role of the unfolded protein response in cell death
R. Kim (2005)
Genetic control of programmed cell death in the nematode C. elegans
H. Ellis (1986)
Mechanisms of pathogen entry through the endosomal compartments
J. Gruenberg (2006)
Golgins and GTPases, giving identity and structure to the Golgi apparatus.
B. Short (2005)
Ectopic expression of CHOP (GADD153) induces apoptosis in M1 myeloblastic leukemia cells
M. Matsumoto (1996)
Molecular characterization of two Arabidopsis Ire1 homologs, endoplasmic reticulum-located transmembrane protein kinases.
N. Koizumi (2001)
ER stress (PERK/eIF2α phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation
Y. Kouroku (2007)
Autophagy and the cvt pathway both depend on AUT9.
T. Lang (2000)
Inhibition of N-linked glycosylation causes apoptosis in hamster BHK21 cells.
M. Yoshimi (2000)
Human GLTP and mutant forms of ACD11 suppress cell death in the Arabidopsis acd11 mutant
Nikolaj H. T. Petersen (2008)
A Giant Ubiquitin-conjugating Enzyme Related to IAP Apoptosis Inhibitors
Hans-Peter Hauser (1998)
Hormone response complex in a novel abscisic acid and cycloheximide-inducible barley gene.
Q. Shen (1993)
Differential Effects of Endoplasmic Reticulum Stress-induced Autophagy on Cell Survival*
W. Ding (2007)
The plant immune system
J. Jones (2006)
Vacuolar processing enzyme is self‐catalytically activated by sequential removal of the C‐terminal and N‐terminal propeptides
N. Hiraiwa (1999)
Vacuolar processing enzyme: an executor of plant cell death.
I. Hara-Nishimura (2005)
Deficiency in Apoptotic Effectors BAX and BAK Reveals an Autophagic Cell Death Pathway Initiated by Photodamage to the Endoplasmic Reticulum
E. Buytaert (2006)
Plant programmed cell death: can't live with it; can't live without it.
B. Williams (2008)
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death
G. Kroemer (2005)
Phylogenetic analysis of methanogens from the bovine rumen
M. F. Whitford (2001)
The self-incompatibility response in Papaver rhoeas pollen causes early and striking alterations to organelles
A. Geitmann (2004)
Golgins and GTPases
B. 1221–1228. Short (2005)
Is the autophagy machinery an executioner of programmed cell death in plants?
Jean-Luc Cacas (2009)
Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome
W. Ding (2008)
M. Grant (2006)
Degrade or die: a dual function for autophagy in the plant immune response.
J. Greenberg (2005)
Death of mitochondria during programmed cell death of leaf mesophyll cells
Tūrs Selga (2005)
Anticipating Endoplasmic Reticulum Stress: A Novel Early Response before Pathogenesis-Related Gene Induction
Edith P. W. M. Jelitto-Van Dooren (1999)
Molecular machinery for non-vesicular trafficking of ceramide
K. Hanada (2003)
Over-expression of the cell death regulator BAX inhibitor-1 in barley confers reduced or enhanced susceptibility to distinct fungal pathogens
V. Babaeizad (2008)
BAX Inhibitor-1, an ancient cell death suppressor in animals and plants with prokaryotic relatives
Justus-Liebig-University Giessen (2004)
Bax-induced cell death
D. Baek (2004)
Autophagy Is Activated for Cell Survival after Endoplasmic ReticulumStress
M. Ogata (2006)
Cellular response to endoplasmic reticulum stress: a matter of life or death
M. Boyce (2006)
Light enhances the unfolded protein response as measured by BiP2 gene expression and the secretory GFP-2SC marker in Arabidopsis.
D. Lu (2008)
Processing of ATG8s, Ubiquitin-Like Proteins, and Their Deconjugation by ATG4s Are Essential for Plant Autophagy
K. Yoshimoto (2004)
Endoplasmic Reticulum Stress Triggers Autophagy*
T. Yorimitsu (2006)
Golgi-Mediated Vacuolar Sorting of the Endoplasmic Reticulum Chaperone BiP May Play an Active Role in Quality Control within the Secretory Pathway
P. Pimpl (2005)
Aut5/Cvt17p, a putative lipase essential for disintegration of autophagic bodies inside the vacuole.
U. D. Epple (2001)
Autophagosome requires specific early Sec proteins for its formation and NSF/SNARE for vacuolar fusion.
N. Ishihara (2001)
Analyses of APG13 gene involved in autophagy in yeast, Saccharomyces cerevisiae.
T. Funakoshi (1997)
Expression profiling on soybean leaves reveals integration of ER- and osmotic-stress pathways
André ST Irsigler (2007)
Characterization of two homologs of Ire1p, a kinase/endoribonuclease in yeast, in Arabidopsis thaliana.
S. Noh (2002)
Lipoxygenase-mediated production of fatty acid hydroperoxides is a specific signature of the hypersensitive reaction in plants
Jean-Luc Montillet (2002)
Autophagy and plant innate immunity
Montrell D Seay (2006)
Identification of proteins interacting with Arabidopsis ACD11.
Nikolaj H. T. Petersen (2009)
Identification of an Arabidopsis transmembrane bZIP transcription factor involved in the endoplasmic reticulum stress response.
H. Tajima (2008)
Tor-Mediated Induction of Autophagy via an Apg1 Protein Kinase Complex
Y. Kamada (2000)
The plant ER-Golgi interface: a highly structured and dynamic membrane complex.
P. Moreau (2007)
Autophagy and Cell-Death Proteases in Plants: Two Wheels of a Funeral Cart
P. Bozhkov (2007)
Endoplasmic reticulum stress: signaling the unfolded protein response.
Elida Lai (2007)
Disruption of Autophagy Results in Constitutive Oxidative Stress in Arabidopsis
Y. Xiong (2007)
Organization of translocon complexes in ER membranes.
A. V. Nikonov (2003)
Essential roles of Atg 5 and FADD in autophagic cell death : dissection of autophagic cell death into vacuole formation and cell death
O. PyoJ. (2005)
Apoptosis: A Basic Biological Phenomenon with Wide-ranging Implications in Tissue Kinetics
J. Kerr (1972)
Light-Dependent Death of Maize lls1 Cells Is Mediated by Mature Chloroplasts1
J. Gray (2002)
Activation of Caspase-12, an Endoplastic Reticulum (ER) Resident Caspase, through Tumor Necrosis Factor Receptor-associated Factor 2-dependent Mechanism in Response to the ER Stress*
T. Yoneda (2001)
The endoplasmic reticulum and the unfolded protein response.
J. D. Malhotra (2007)
An Abscisic Acid-Induced Protein, HVA22, Inhibits Gibberellin-Mediated Programmed Cell Death in Cereal Aleurone Cells1[W][OA]
Woei-Jiun Guo (2008)
The APG8/12-activating Enzyme APG7 Is Required for Proper Nutrient Recycling and Senescence in Arabidopsis thaliana *
J. H. Doelling (2002)
Plant pathogens and integrated defence responses to infection
J. Dangl (2001)
The nucellus degenerates by a process of programmed cell death during the early stages of wheat grain development
F. Domínguez (2001)
Mediators of endoplasmic reticulum stress‐induced apoptosis
E. Szegezdi (2006)
Oxylipin profiling in pathogen-infected potato leaves.
C. Göbel (2002)
Mechanisms of neural cell death: Implications for development of neuroprotective treatment strategies
A. Yakovlev (2004)
Bax Inhibitor-1 Is a pH-dependent Regulator of Ca2+ Channel Activity in the Endoplasmic Reticulum*
H. Kim (2008)
Autophagy Is Enhanced and Floral Development Is Impaired in AtHVA22d RNA Interference Arabidopsis[C][W][OA]
C. Chen (2009)
‘Men are but worms:’⋆ neuronal cell death in C. elegans and vertebrates
G. Putcha (2004)
A MYB Transcription Factor Regulates Very-Long-Chain Fatty Acid Biosynthesis for Activation of the Hypersensitive Cell Death Response in Arabidopsis[W][OA]
S. Raffaele (2008)
Vacuolar Processing Enzyme Is Essential for Mycotoxin-induced Cell Death in Arabidopsis thaliana*
M. Kuroyanagi (2005)
Endoplasmic reticulum stress: cell life and death decisions.
C. Xu (2005)
ChloroP, a neural network‐based method for predicting chloroplast transit peptides and their cleavage sites
O. Emanuelsson (1999)
Response to Cacas and Diamond: Is the autophagy machinery an executioner of programmed cell death in plants?
Andrew J. Love (2009)
Endoplasmic reticulum stress activates the expression of a sub-group of protein disulfide isomerase genes and AtbZIP60 modulates the response in Arabidopsis thaliana
D. Lu (2008)
VPEγ Exhibits a Caspase-like Activity that Contributes to Defense against Pathogens
E. Rojo (2004)
A Plant Vacuolar Protease, VPE, Mediates Virus-Induced Hypersensitive Cell Death
N. Hatsugai (2004)
Starvation‐induced expression of autophagy‐related genes in Arabidopsis
T. Rose (2006)
Functional association of cell death suppressor, Arabidopsis Bax inhibitor-1, with fatty acid 2-hydroxylation through cytochrome b₅.
M. Nagano (2009)
A New Inhibitor of Apoptosis from Vaccinia Virus and Eukaryotes
Caroline Gubser (2007)
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009
G. Kroemer (2009)
Significance of GTP Hydrolysis in Ypt1p-regulated Endoplasmic Reticulum to Golgi Transport Revealed by the Analysis of Two Novel Ypt1-GAPs*
A. De Antoni (2002)
An Arabidopsis thaliana cDNA complementing a hamster apoptosis suppressor mutant.
P. Gallois (1997)
BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress.
Han-Jung Chae (2004)
A Novel Arabidopsis Gene Causes Bax-like Lethality in Saccharomyces cerevisiae*
M. Kawai-yamada (2005)
Golgi disassembly in apoptosis: cause or effect?
C. Machamer (2003)
The Phosphorylation State and Expression of Soybean BiP Isoforms Are Differentially Regulated following Abiotic Stresses*
J. C. Cascardo (2000)
Ion channels and mem
I. Szabò (2004)
Autophagy and plant
M. Seay (2006)
Nuclear regulators with a second home in organelles.
K. Krause (2009)
Autophagic Nutrient Recycling in Arabidopsis Directed by the ATG8 and ATG12 Conjugation Pathways1
Allison R Thompson (2005)
Does the plant mitochondrion integrate cellular stress and regulate programmed cell death?
A. Jones (2000)
Conservation between animals and plants of the cis-acting element involved in the unfolded protein response.
Dong-Ha Oh (2003)
Degradation of Lipid Vesicles in the Yeast Vacuole Requires Function of Cvt17, a Putative Lipase*
S. Teter (2001)
Methods for Monitoring Autophagy from Yeast to Human
D. Klionsky (2007)
Cloning and characterization of TPE4A, a thiol-protease gene induced during ovary senescence and seed germination in pea.
M. Cerćos (1999)
Mycotoxins reveal connections between plants and animals in apoptosis and ceramide signaling
D. Gilchrist (1997)
Intermediate Organelles of the Plant Secretory Pathway: Identity and Function
O. Foresti (2008)
Knockout of Arabidopsis accelerated-cell-death11 encoding a sphingosine transfer protein causes activation of programmed cell death and defense.
P. Brodersen (2002)
Endosome to Golgi Retrieval of the Vacuolar Protein Sorting Receptor, Vps10p, Requires the Function of the VPS29, VPS30, and VPS35 Gene Products
M. Seaman (1997)
Media - tors of endoplasmic reticulum stress - induced apoptosis
E. Szegezdi (2006)
An Arabidopsis transcription factor, AtbZIP60, regulates the endoplasmic reticulum stress response in a manner unique to plants.
Y. Iwata (2005)
BAX and BAK Regulation of Endoplasmic Reticulum Ca2+: A Control Point for Apoptosis
L. Scorrano (2003)
Unfolded protein response followed by induction of cell death in cultured tobacco cells treated with tunicamycin
Y. Iwata (2004)
Enhanced accumulation of BiP in transgenic plants confers tolerance to water stress.
F. Alvim (2001)
Leaf Senescence and Starvation-Induced Chlorosis Are Accelerated by the Disruption of an Arabidopsis Autophagy Gene1
Hideki Hanaoka (2002)
Are metacaspases caspases?
D. Vercammen (2007)
Mitochondrial retrograde regulation in plants.
D. Rhoads (2007)
Identification of novel mitochondrial membrane protein (Cdf 3) from Arabidopsis thaliana and its functional analysis in a yeast system.
Kyung-Min Kim (2007)
Autophagy is required for necrotic cell death in Caenorhabditis elegans
C. Samara (2008)
The selectivity of autophagy and its role in cell death and survival
L. Yu (2008)
A unified nomenclature for yeast autophagy-related genes.
D. Klionsky (2003)
during the unfolded protein response in Arabidopsis thaliana
K. Obara (2006)
Caspases and programmed cell death in the hypersensitive response of plants to pathogens
Olga María del Pozo (1998)
The highly conserved DAD1 protein involved in apoptosis is required for N‐linked glycosylation
T. Makishima (1997)
An Arabidopsis aspartic protease functions as an anti‐cell‐death component in reproduction and embryogenesis
Xiaochun Ge (2005)
Mammalian Bax-induced plant cell death can be down-regulated by overexpression of Arabidopsis Bax Inhibitor-1 (AtBI-1)
M. Kawai-yamada (2001)
Involvement of Lipoxygenase-dependent Production of Fatty Acid Hydroperoxides in the Development of the Hypersensitive Cell Death induced by Cryptogein on Tobacco Leaves*
C. Rustérucci (1999)
A novel patatin-like protein from cotton plant, GhPat1, is co-expressed with GhLox1 during Xanthomonas campestris-mediated hypersensitive cell death
Jean-Luc Cacas (2008)
The barley apoptosis suppressor homologue BAX inhibitor-1 compromises nonhost penetration resistance of barley to the inappropriate pathogen Blumeria graminis f. sp. tritici.
R. Eichmann (2004)
Identification of the pollen self-incompatibility determinant in Papaver rhoeas
M. Wheeler (2009)
Dissection of Autophagosome Biogenesis into Distinct Nucleation and Expansion Steps
H. Abeliovich (2000)
Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes
S. Shimizu (2004)
Fatty acid ketodienes and fatty acid ketotrienes: Michael addition acceptors that accumulate in wounded and diseased Arabidopsis leaves.
S. Vollenweider (2000)
How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?
J. Chipuk (2008)
Isolation and characterization of a putative transducer of endoplasmic reticulum stress in Oryza sativa.
Y. Okushima (2002)
DAD1, the defender against apoptotic cell death, is a subunit of the mammalian oligosaccharyltransferase.
D. Kelleher (1997)
Chlorophyll breakdown: Pheophorbide a oxygenase is a Rieske-type iron–sulfur protein, encoded by the accelerated cell death 1 gene
Adriana Pružinská (2003)
Genomic Analysis of the Unfolded Protein Response in Arabidopsis Shows Its Connection to Important Cellular Processes Online version contains Web-only data. Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.007609.
I. M. Martínez (2003)
Autophagic Fungal Cell Death Is Necessary for Infection by the Rice Blast Fungus
Claire Veneault-Fourrey (2006)
Traffic between the plant endoplasmic reticulum and Golgi apparatus: to the Golgi and beyond.
Loren A. Matheson (2006)
The pre‐autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation
K. Suzuki (2001)
Timing is everything: regulatory overlap in plant cell death.
A. J. Love (2008)
Eating the endoplasmic reticulum: quality control by autophagy.
T. Yorimitsu (2007)
Degradation of Oxidized Proteins by Autophagy during Oxidative Stress in Arabidopsis1[W][OA]
Y. Xiong (2006)
Evolutionarily conserved cytoprotection provided by Bax Inhibitor-1 homologs from animals, plants, and yeast.
Han-Jung Chae (2003)
2006)Autophagy is activated for cell survival after endoplasmic reticulum stress
M. Ogata (2006)
A membrane-tethered transcription factor defines a branch of the heat stress response in Arabidopsis thaliana
H. Gao (2008)
Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability.
W. Ding (2007)
Lesion mimic mutants: keys for deciphering cell death and defense pathways in plants?
Séverine Lorrain (2003)
BI-1 protects cells from oxygen glucose deprivation by reducing the calcium content of the endoplasmic reticulum
B. Westphalen (2005)
The hypersensitive response; the centenary is upon us but how much do we know?
L. Mur (2008)
Arabidopsis ATG6 is required to limit the pathogen-associated cell death response
S. Patel (2008)
A Novel Mechanism for Regulating Activity of a Transcription Factor That Controls the Unfolded Protein Response
J. Cox (1996)
Essential Roles of Atg5 and FADD in Autophagic Cell Death
Jong-Ok Pyo (2005)
Comparison between the effects of fusicoccin, Tunicamycin, and Brefeldin A on programmed cell death of cultured sycamore (Acer pseudoplatanus L.) cells
M. Malerba (2004)
Apoptosis--the Calcium Connection
N. Demaurex (2003)
Inducers of Plant Systemic Acquired Resistance Regulate NPR1 Function through Redox Changes
Zhonglin Mou (2003)
The plant homologue of the defender against apoptotic death gene is down‐regulated during senescence of flower petals 1
D. Orzáez (1997)
Expression of an evolutionarily distinct novel BiP gene during the unfolded protein response in Arabidopsis thaliana.
S. Noh (2003)
Autophagic Components Contribute to Hypersensitive Cell Death in Arabidopsis
D. Hofius (2009)
Programmed cell death in host-symbiont associations, viewed through the Gene Ontology
M. Chibucos (2009)
Review of innate and specific immunity in plants and animals
M. Iriti (2007)
Characterization of Lipid Rafts from Medicago truncatula Root Plasma Membranes: A Proteomic Study Reveals the Presence of a Raft-Associated Redox System1[W]
B. Lefebvre (2007)
Transcription analysis of Arabi
U. I. Flügge (2006)
from yeast to human
H. Koiwa (2003)
Reactive oxygen species and hormonal control of cell death.
Kirk Overmyer (2003)
Gadd153 Sensitizes Cells to Endoplasmic Reticulum Stress by Down-Regulating Bcl2 and Perturbing the Cellular Redox State
K. McCullough (2001)
Molecular cloning of a human cDNA encoding a novel protein, DAD1, whose defect causes apoptotic cell death in hamster BHK21 cells.
T. Nakashima (1993)
Arabidopsis ACCELERATED CELL DEATH2 Modulates Programmed Cell Death[W]
N. Yao (2005)
Arabidopsis Protein Disulfide Isomerase-5 Inhibits Cysteine Proteases during Trafficking to Vacuoles before Programmed Cell Death of the Endothelium in Developing Seeds[W]
Christine Andème Ondzighi (2008)
Caspase-resistant Golgin-160 disrupts apoptosis induced by secretory pathway stress and ligation of death receptors.
Rebecca S Maag (2005)
Arabidopsis Bax inhibitor-1 functions as an attenuator of biotic and abiotic types of cell death.
N. Watanabe (2006)
Regulation of plant defense responses in Arabidopsis by EDR2, a PH and START domain-containing protein.
Dingzhong Tang (2005)
Activation of the fatty acid alpha-dioxygenase pathway during bacterial infection of tobacco leaves. Formation of oxylipins protecting against cell death.
M. Hámberg (2003)
Specific binding to a novel and essential Golgi membrane protein (Yip1p) functionally links the transport GTPases Ypt1p and Ypt31p
X. Yang (1998)
Caspase-2 Is Localized at the Golgi Complex and Cleaves Golgin-160 during Apoptosis
M. Mancini (2000)
and its role in cell death and survival
K. Zhang (2004)
The selectivity of
L. Yu (2008)
Salt stress responses in Arabidopsis utilize a signal transduction pathway related to endoplasmic reticulum stress signaling
J. Liu (2007)
Abrogation of disease development in plants expressing animal antiapoptotic genes
M. Dickman (2001)
Yop1p, the Yeast Homolog of the Polyposis Locus Protein 1, Interacts with Yip1p and Negatively Regulates Cell Growth*
M. Calero (2001)
Heterotrimeric G protein signaling in the Arabidopsis unfolded protein response
Shiyu Wang (2007)
Endoplasmic reticulum stress-induced programmed cell death in soybean cells
Anna Zuppini (2004)
Conserved ERAD-Like Quality Control of a Plant Polytopic Membrane Protein
J. Mueller (2005)
Messengers of cell death: apoptotic signaling in health and disease.
D. Rossi (2003)
Making Sense of Senescence (Molecular Genetic Regulation and Manipulation of Leaf Senescence)
S. Gan (1997)
DCD – a novel plant specific domain in proteins involved in development and programmed cell death
R. Tenhaken (2005)
Molecular characterization of two plant BI-1 homologues which suppress Bax-induced apoptosis in human 293 cells
N. Bolduc (2002)
The Arabidopsis thaliana TIR-NB-LRR R-protein, RPP1A; protein localization and constitutive activation of defence by truncated alleles in tobacco and Arabidopsis.
L. Michael Weaver (2006)
Autophagic recycling: lessons from yeast help define the process in plants.
Allison R Thompson (2005)
Lipid Rafts in Higher Plant Cells
S. Mongrand (2004)
WoLF PSORT: protein localization predictor
P. Horton (2007)
Antisense down regulation of NtBI‐1 in tobacco BY‐2 cells induces accelerated cell death upon carbon starvation
Nathalie Bolduc (2002)
NtLRP1, a tobacco leucine-rich repeat gene with a possible role as a modulator of the hypersensitive response.
Alban Jacques (2006)
The BAG proteins: a ubiquitous family of chaperone regulators
M. Kabbage (2008)
Autophagy Counterbalances Endoplasmic Reticulum Expansion during the Unfolded Protein Response
S. Bernales (2006)
Autophagy in Development and Stress Responses of Plants
D. Bassham (2006)
Endoplasmic reticulum stress responses
M. Schröder (2007)
Expression of the high capacity calcium-binding domain of calreticulin increases bioavailable calcium stores in plants
S. Wyatt (2004)
Ultraviolet-C Overexposure Induces Programmed Cell Death in Arabidopsis, Which Is Mediated by Caspase-like Activities and Which Can Be Suppressed by Caspase Inhibitors, p35 and Defender against Apoptotic Death*
A. Danon (2004)
Arabidopsis bZIP60 Is a Proteolysis-Activated Transcription Factor Involved in the Endoplasmic Reticulum Stress Response[W]
Y. Iwata (2008)
What happened to plant caspases?
L. Bonneau (2008)
Metacaspase-dependent programmed cell death is essential for plant embryogenesis
M. F. Suárez (2004)
Ceramides modulate programmed cell death in plants.
Hua Liang (2003)
Oxytosis: A novel form of programmed cell death.
S. Tan (2001)
Autophagy Regulates Programmed Cell Death during the Plant Innate Immune Response
Y. Liu (2005)
The combined action of 9 lipoxygenase and galactolipase is sufficient to bring about programmed cell death during tobacco hypersensitive response
Jean-Luc Cacas (2005)
Transcription Analysis of Arabidopsis Membrane Transporters and Hormone Pathways during Developmental and Induced Leaf Senescence1[W]
E. van der Graaff (2006)
A COMPARATIVE LIGHT‐ AND ELECTRON‐MICROSCOPIC STUDY OF MICROSPOROGENESIS IN MALE‐FERTILE AND CYTOPLASMIC MALE‐STERILE SUNFLOWER (HELIANTHUS ANNUUS)
H. Horner (1977)
A New Cell Wall Located N-rich Protein is Strongly Induced During the Hypersensitive Response in Glycine Max L.
A. Ludwig (2004)
2003)The STT3a subunit isoform of the Arabidopsis oligosaccharyltransferase controls adaptive responses to salt/osmotic stress
H. Koiwa (2003)
Mice lacking Dad1, the defender against apoptotic death-1, express abnormal N-linked glycoproteins and undergo increased embryonic apoptosis.
N. A. Hong (2000)
A protein conjugation system essential for autophagy
N. Mizushima (1998)
Mitochondrial retrograde regulation tuning fork in nuclear genes expressions of higher plants.
J. Yang (2008)
Salt tolerance of Arabidopsis thaliana requires maturation of N-glycosylated proteins in the Golgi apparatus
J. S. Kang (2008)
Autophagy protein 6 (ATG6) is required for pollen germination in Arabidopsis thaliana
N. Harrison-Lowe (2008)
Nitric Oxide and Endoplasmic Reticulum Stress
T. Gotoh (2006)
Initiation of Runaway Cell Death in an Arabidopsis Mutant by Extracellular Superoxide
T. Jabs (1996)
Development by self-digestion: molecular mechanisms and biological functions of autophagy.
B. Levine (2004)
Bax-induced cell death of Arabidopsisis meditated through reactive oxygen-dependent and -independent processes
Dongwon Baek (2004)
Golgi structure in stress sensing and apoptosis.
S. W. Hicks (2005)
Visualization of autophagy in Arabidopsis using the fluorescent dye monodansylcadaverine and a GFP-AtATG8e fusion protein.
Anthony L Contento (2005)
Regulation of an ATG7-beclin 1 Program of Autophagic Cell Death by Caspase-8
L. Yu (2004)
Autophagy: highlighting a novel player in the autoimmunity scenario.
A. Lleo (2007)
Protein Aggregates are Transported to Vacuoles by Macroautophagic Mechanism in Nutrient-Starved Plant Cells
K. Toyooka (2006)
Caspase structure, proteolytic substrates, and function during apoptotic cell death
Dw Nicholson (1999)
An Alternative, Non-Apoptotic Form of Programmed Cell Death
Ozone-Induced Programmed Cell Death in the Arabidopsis radical-induced cell death1 Mutant1
K. Overmyer (2005)
Overexpression of Bax inhibitor suppresses the fungal elicitor-induced cell death in rice (Oryza sativa L) cells.
H. Matsumura (2003)
Ion channels and membrane rafts in apoptosis
I. Szabò (2004)
Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma.
A. Uren (2000)
The STT3a Subunit Isoform of the Arabidopsis Oligosaccharyltransferase Controls Adaptive Responses to Salt/Osmotic Stress Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.013862.
H. Koiwa (2003)
An Arabidopsis Homolog of Yeast ATG6/VPS30 Is Essential for Pollen Germination1[W]
Y. Fujiki (2007)
Identification and Characterization of Endoplasmic Reticulum-Associated Degradation Proteins Differentially Affected by Endoplasmic Reticulum Stress1
Mariana E Kirst (2005)
Gene expression in response to endoplasmic reticulum stress in Arabidopsis thaliana
Shinya Kamauchi (2005)
Growth Arrest and Autophagy Are Required for Salivary Gland Cell Degradation in Drosophila
D. Berry (2007)
Involvement of cathepsin B in the plant disease resistance hypersensitive response.
Eleanor M Gilroy (2007)
Self-incompatibility in Papaver: signalling to trigger PCD in incompatible pollen.
Maurice Bosch (2008)
Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae.
Akihiro Matsuura (1997)
Defects in N‐glycosylation induce apoptosis in yeast
P. Hauptmann (2006)
Function of Lysosomes and Lysosomal Enzymes in the Senescing Corolla of the Morning Glory (Ipomoea purpurea)
P. Matile (1971)
This paper is referenced by
Regulated Suicide for Survival
Dr. Rita Rani Talukdar (2019)
Fertility in barley flowers depends on Jekyll functions in male and female sporophytes.
V. Radchuk (2012)
Potential Effects, Biology and Management Options of Coffee Leaf Rust (Hemileia Vastatrix): A Review
Masreshaw Yirga (2020)
TUNEL Assay and DAPI Staining Revealed Few Alterations of Cellular Morphology in Naturally and Artificially Aged Seeds of Cultivated Flax
Yong-Bi Fu (2018)
Nuclear Dismantling Events: Crucial Steps During the Execution of Plant Programmed Cell Death
Fernando Domínguez (2015)
Out for a Walk Along the Secretory Pathway During Programmed Cell Death
Jean-Luc Cacas (2015)
The fatal effect of tungsten on Pisum sativum L. root cells: indications for endoplasmic reticulum stress-induced programmed cell death
Ioannis-Dimosthenis S. Adamakis (2011)
Light and temperature induce variations in the density and ultrastructure of the secretory spaces in the diesel-tree (Copaifera langsdorffii Desf.—Leguminosae)
Tatiane Maria Rodrigues (2013)
Programmed Cell Death Controlled by ANAC033/SOMBRERO Determines Root Cap Organ Size in Arabidopsis
M. Fendrych (2014)
How Very-Long-Chain Fatty Acids Could Signal Stressful Conditions in Plants?
Antoine De Bigault Du Granrut (2016)
Programmed Cell Death Occurs Asymmetrically during Abscission in Tomato[C][W][OA]
Tal Bar-Dror (2011)
The Botanical Dance of Death: Programmed Cell Death in Plants
J. Kacprzyk (2011)
Determination of ACC-induced cell-programmed death in roots of Vicia faba ssp. minor seedlings by acridine orange and ethidium bromide staining
A. Byczkowska (2012)
Phospholipase A in Plant Immunity
Susana Rivas (2014)
Ascorbate and Glutathione: The Heart of the Redox Hub1
C. Foyer (2011)
Redox regulation of the cell cycle in Arabidopsis thaliana
Ambra de Simone (2016)
Variations on a theme: plant autophagy in comparison to yeast and mammals
Tamar Avin-Wittenberg (2011)
The natural compound trans-chalcone induces programmed cell death in Arabidopsis thaliana roots.
C. Díaz-Tielas (2012)
Drought tolerance mechanisms and their molecular basis
P. Verslues (2014)
The failure to express a protein disulphide isomerase-like protein results in a floury endosperm and an endoplasmic reticulum stress response in rice
Xiaohua Han (2012)
The endoplasmic reticulum stress induced by highly expressed OsrAAT reduces seed size via pre-mature programmed cell death
Liping Zhang (2013)
Avoiding transport bottlenecks in an expanding root system: xylem vessel development in fibrous and pioneer roots under field conditions.
A. Bagniewska-Zadworna (2012)
Signaling Pathways of Aluminum-Induced Programmed Cell Death in Higher Plants
Huyi He (2015)
Antioxidant system in programmed cell death of sycamore (Acer pseudoplatanus L.) cultured cells
N. Contran (2011)
Nodulin 22, a novel small heat-shock protein of the endoplasmic reticulum, is linked to the unfolded protein response in common bean.
Jonathan Rodríguez-López (2014)
Programmed cell death of secretory cavity cells in fruits of Citrus grandis cv. Tomentosa is associated with activation of caspase 3-like protease
Peiwei Liu (2012)
Tungsten Toxicity in Plants
I. Adamakis (2012)
To Live or Die: Autophagy in Plants
Brice E. Floyd (2015)
The soluble proteome of tobacco Bright Yellow-2 cells undergoing H2O2-induced programmed cell death
C. Vannini (2012)
Nitrogen remobilization during leaf senescence: lessons from Arabidopsis to crops.
M. Havé (2017)
Plant Programmed Cell Death
N. Gunawardena (2015)
Two proteases with caspase‐3‐like activity, cathepsin B and proteasome, antagonistically control ER‐stress‐induced programmed cell death in Arabidopsis
Yao-Min Cai (2018)See more