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Mechanism Of Action Of A Lipophilic Derivative Of Salicylic Acid On Normal Skin

J. L. Lévêque, P. Corcuff, G. Gonnord, C. Montastier, B. Renault, R. Bazin, G. Piérard, M. Poelman
Published 1995 · Medicine, Chemistry

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Background/aims: Keratolytics are agents used for a very long period of time to improve various skin disorders such as acne, hyperkeratoses, ichtyose etc. Very little is known about their mechanism of action on healthy skin. On man, the chronic application of a cosmetic cream containing a lipophilic derivative of Salicyclic acid (LSA) markedly improves the aspect and texture of the skin. Different methods were used to investigate the mechanisms of action of this new compound, compared to salicyclic acid.
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