Online citations, reference lists, and bibliographies.
← Back to Search

Acid‐base Properties Of Terbutaline In Terms Of Protonation Macro‐ And Microconstants

K. Takács-Novák, B. Noszál, M. Tökés-Kövesdi, G. Szász
Published 1995 · Medicine, Chemistry

Save to my Library
Download PDF
Analyze on Scholarcy
Share
The acid/base chemistry of terbutaline was characterized at the molecular level in terms of protonation macroconstants and microconstants. The macroconstants were measured by potentiometry and calculated by standard evaluation methods.
This paper references
Acid - base properties of bioligands
B. Noszal (1990)
10.1021/JM00281A025
Resolution of terbutaline, a new -sympathomimetic amine.
K. Wetterlin (1972)
Zwitterion formation upon deprotonation in ~-3,4-dihydroxyphenylalanine
R. B. Martin (1971)
Pharmacokinetic evaluation in man of terbutaline given as 590 : 341 - 353 separate enantiomers and as the racemate
L. Borgstrom (1989)
10.1016/0731-7085(93)80198-A
Coulometric determination of some antiasthmatics.
K. Nikolić (1993)
Quantitative determination by ion
R. Modin (1971)
10.1016/0378-5173(94)00176-6
Lipophilicity of amphoteric molecules expressed by the true partition coefficient
K. Takács-Novák (1995)
Rota-microspeciation of aspartic acid
B. Noszal (1989)
Terbutaline sulfate
S. Ahuja (1990)
10.1111/J.1365-2125.1989.TB05334.X
Pharmacokinetic evaluation in man of terbutaline given as separate enantiomers and as the racemate.
L. Borgström (1989)
10.1111/j.2042-7158.1989.tb06506.x
Determination of microscopic dissociation constants of 3‐hydroxy‐α‐(methylamino)methyl‐benzenemethanol by a spectral deconvolution method
B. Quintero (1989)
10.1021/AC00198A009
Rota-microspeciation of aspartic acid and asparagine
B. Noszál (1989)
10.1016/0021-9673(92)85397-C
Comparison of isotachophoresis, capillary zone electrophoresis and high-performance liquid chromatography for the determination of salbutamol, terbutaline sulphate and fenoterol hydrobromide in pharmaceutical dosage forms.
M. Ackermans (1992)
10.1021/J100686A021
Zwitterion formation upon deprotonation in L-3, 4-dihydroxyphenylalanine and other phenolic amines.
Martin Rb (1971)
10.1002/ELAN.1140040415
Analysis of terbutaline in human plasma by high-performance liquid chromatography with electrochemical detection using a micro-electrochemical flow cell.
K. Sagar (1992)
10.1007/978-94-009-5548-6
The determination of ionization constants
A. Albert (1971)
10.1002/JPS.2600791116
Protonation equilibria of quinolone antibacterials.
K. Takács-Novák (1990)
10.1016/s0010-8545(96)90160-5
Biocoordination chemistry : coordination equilibria in biologically active systems
K. Burger (1990)
10.1021/j100686a021
Zwitterion formation upon deprotonation in L-3, 4-dihydroxyphenylalanine and other phenolic amines.
R. Martin (1971)
Quantitative determination by ion pair extraction . Part . 8 . Extraction of aminophenols and amino - alcohols by bis ( 2 - ethylhexyl ) phosphoric acid
R. Modin (1971)



This paper is referenced by
10.2527/1998.761173X
The pharmacokinetics, metabolism, and tissue residues of beta-adrenergic agonists in livestock.
D. Smith (1998)
10.1016/S0003-2670(01)00810-8
Multi-wavelength spectrophotometric determination of acid dissociation constants: a validation study
K. Tam (2001)
[Physico-chemical profiling of centrally acting molecules for prediction of pharmacokinetic properties].
K. Deák (2008)
10.5599/obp.7.1
PHYSICOCHEMICAL PROFILING IN DRUG RESEARCH AND DEVELOPMENT
K. Takács-Novák (2014)
10.1016/J.FITOTE.2006.09.016
Alpha-bulnesene, a PAF inhibitor isolated from the essential oil of Pogostemon cablin.
Ying-Chieh Tsai (2007)
10.1016/B0-08-045044-X/00143-7
5.25 – In Silico Prediction of Ionization
R. Fraczkiewicz (2007)
10.1016/j.jpba.2016.09.019
Biorelevant physicochemical profiling of (E)‐ and (Z)‐resveratrol determined from isomeric mixtures
G. Orgován (2017)
10.1002/cmdc.202000164
Physicochemical Properties of Zwitterionic Drugs in Therapy
K. Mazák (2020)
10.1016/S0731-7085(98)00010-7
Multiwavelength spectrophotometric determination of acid dissociation constants of ionizable drugs.
R. Allen (1998)
10.15671/HJBC.2018.210
Determination of Acidic Dissociation Constants of Chlorthalidone and Terbutaline in Water Using DFT and Ab Initio Methods
F. Kiani (2018)
10.1080/10826076.2013.809545
SIMULTANEOUS DETERMINATION OF EIGHT FLAVONOIDS AND POGOSTONE IN POGOSTEMON CABLIN BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY
P. Li (2014)
10.1021/jm901421c
The permeation of amphoteric drugs through artificial membranes--an in combo absorption model based on paracellular and transmembrane permeability.
K. Tam (2010)
10.1016/S0731-7085(99)00238-1
Multiwavelength spectrophotometric determination of acid dissociation constants part V: microconstants and tautomeric ratios of diprotic amphoteric drugs.
K. Takács-Novák (2000)
10.1016/B978-0-12-409547-2.02610-X
In Silico Prediction of Ionization
R. Fraczkiewicz (2007)
10.1016/S0168-3659(03)00092-0
A novel pulsed-release system based on swelling and osmotic pumping mechanism.
Y. Zhang (2003)
10.1016/S0731-7085(99)00041-2
Multiwavelength spectrophotometric determination of acid dissociation constants: Part III. Resolution of multi-protic ionization systems.
R. C. Mitchell (1999)
Semantic Scholar Logo Some data provided by SemanticScholar