Online citations, reference lists, and bibliographies.

The Impact Of Multimorbidity On Sexual Function In Middle-aged And Older Women: Beyond The Single Disease Perspective.

Ayesha A. Appa, J. Creasman, J. Brown, S. K. Van Den Eeden, D. Thom, L. Subak, A. Huang
Published 2014 · Medicine

Cite This
Download PDF
Analyze on Scholarcy
INTRODUCTION Little is known about sexual activity and function in women with multiple chronic health conditions. AIM To examine the impact of multimorbidity on sexual activity and function in middle-aged and older women. METHODS Multiethnic cross-sectional cohort of 1,997 community-dwelling women (mean age of 60.2 [±9.5] years) in California. Structured questionnaires assessed prior diagnoses of common cardiometabolic, colorectal, neuropsychiatric, respiratory, musculoskeletal, and genitourinary conditions. MAIN OUTCOME MEASURES Sexual desire, frequency of sexual activity, overall sexual satisfaction, and specific sexual problems (i.e., difficulty with arousal, lubrication, orgasm, and pain) were assessed by structured questionnaires. RESULTS Seventy-one percent of women had two or more diagnosed chronic conditions. Fifty-nine percent reported low sexual desire, 53% reported less than monthly sexual activity, and 47% reported low overall sexual satisfaction. Multimorbidity was associated with increased odds of reporting low sexual desire (OR = 1.11, 95% CI = 1.06-1.17, per each additional chronic condition), less than monthly sexual activity (OR = 1.11, 95% CI = 1.05-1.17 per each additional condition), and low sexual satisfaction (OR = 1.10, 95% CI = 1.04-1.16 per each additional condition), adjusting for age, race/ethnicity, and partner status. Depression and urinary incontinence were each independently associated with low desire (OR = 1.53, 95% CI = 1.19-1.97, and OR = 1.23, 95% CI = 1.00-1.52, respectively), less than monthly sexual activity (OR = 1.39, 95% CI = 1.06-1.83, and OR = 1.29, 95% CI = 1.02-1.62, respectively), and low sexual satisfaction (OR = 1.49, 95% CI = 1.14-1.93, and OR = 1.38, 95% CI = 1.11-1.73, respectively), adjusting for other types of conditions. After adjustment for total number of chronic conditions, age remained a significant predictor of low desire and less than monthly sexual activity, but not sexual satisfaction. CONCLUSIONS Women with multiple chronic health conditions are at increased risk for decreased sexual function. Depression and incontinence may have particularly strong effects on sexual desire, frequency of activity, and satisfaction in women, independent of other comorbid conditions. Women's overall sexual satisfaction may be more strongly influenced by multimorbidity than age.
This paper references
Longitudinal changes in sexual functioning as women transition through menopause: results from the Study of Women's Health Across the Nation
N. Avis (2009)
Risk factors for female sexual dysfunction in the general population: exploring factors associated with low sexual function and sexual distress.
R. Hayes (2008)
Sexual Dysfunction, Depression, and the Impact of Antidepressants
S. Kennedy (2009)
Female sexual dysfunction related to depression and antidepressant medications.
A. Clayton (2002)
Sex, health, and years of sexually active life gained due to good health: evidence from two US population based cross sectional surveys of ageing
S. Lindau (2010)
Cardiometabolic risk and female sexual health: the Princeton III summary.
M. Miner (2012)
Management of sexual dysfunction in Parkinson’s disease
G. Bronner (2011)
Depression and sexual desire.
R. Phillips (2000)
Diabetes Mellitus and Sexual Function in Middle-Aged and Older Women
K. Copeland (2012)
The relationship between sexual activity and urinary incontinence in older women.
C. Tannenbaum (2006)
Sexual dysfunction in the United States: prevalence and predictors.
E. Laumann (1999)
Sexual function and aging in racially and ethnically diverse women.
Alison J. Huang (2009)
The impact of lower urinary tract symptoms and urinary incontinence on female sexual dysfunction using a validated instrument.
B. Cohen (2008)
Female sexual dys
AE Pontiroli (2010)
Epidemiology/risk factors of sexual dysfunction.
R. Lewis (2004)
Evaluation of sexual function in women with type 2 diabetes mellitus
Seyedeh Seddigeh Fatemi (2009)
Tricyclic side effects without tricyclics in depression.
R. J. Mathew (1980)
Differences in prevalence of urinary incontinence by race/ethnicity.
D. Thom (2006)
Sexual satisfaction and cardiovascular disease: the Women's Health Initiative.
Jennifer S McCall-Hosenfeld (2008)
Mediators of sexual functions in women with diabetes.
Krzysztof Nowosielski (2011)
factors of sexual dysfunction
N Kadri (2004)
The Female Sexual Function Index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function.
R. Rosen (2000)
The Impact of Urinary Incontinence and Its Treatment on Female Sexual Function
Courtenay K. Moore (2010)
Arterial hypertension and female sexual dysfunction in postmenopausal women.
Pasquale de Franciscis (2013)
Management of sexual dysfunction
G Bronner (2012)
women with diabetes
GF Strippoli (2011)
Sexual function among overweight and obese women with urinary incontinence in a randomized controlled trial of an intensive behavioral weight loss intervention.
Alison J. Huang (2009)
Prospective assessment of sexual function in women treated for recurrent major depression.
J. Cyranowski (2004)
Sex Med 2013;10:1044–51
KL Copeland (2013)
Definitions/epidemiology/risk factors for sexual dysfunction.
R. Lewis (2010)
Sexual Dysfunction in Women With Type 1 Diabetes: Long-Term Findings From the DCCT/EDIC Study Cohort
K. Dhatariya (2010)
Sexual dysfunction in women with ESRD requiring hemodialysis.
G. Strippoli (2012)
Sexual dysfunction is common in women with lower urinary tract symptoms and urinary incontinence: results of a cross-sectional study.
A. Salonia (2004)
A study of sexuality and health among older adults in the United States.
S. T. Lindau (2007)
Sexual function and
AJ Huang (2010)
Diabetes mellitus and sexual function in middleaged and older women
KL Copeland (2012)
A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity.
J. Ware (1996)
Noncontrast dynamic magnetic resonance imaging for quantitative assessment of female sexual arousal.
K. Maravilla (2005)
Sexual dysfunction in women: population based epidemiological study
N. Kadri (2002)
Female sexual dysfunction in essential hypertension: a common problem being uncovered
M. Doumas (2006)
Sexual function in women with type 1 diabetes matched with a control group: depressive and psychosocial aspects.
Milena Paola Tagliabue (2011)
Weight loss to treat urinary incontinence in overweight and obese women.
L. Subak (2009)
Female sexual dysfunction and diabetes: a systematic review and meta-analysis.
A. Pontiroli (2013)
Sexual function and patients' perceptions in inflammatory bowel disease: a case–control survey
Laura Marín (2012)
Does hypertension and its pharmacotherapy affect the quality of sexual function in women?
L. E. Duncan (2000)
DCCT/EDIC study cohort. Diabetes Care 2009;32:780–5
SS Fatemi (2009)
Menopause 2009;16:442–52
the Nation (2009)
[Sexual dysfunction].
M. Jasinski (1983)
The impact of aging on sexual function and sexual dysfunction in women: a review of population-based studies.
R. Hayes (2005)
Continuing Medical Education: Urogenital Complaints and Female Sexual Dysfunction (Part 1) (CME)
Salim A. Wehbe (2010)
Sexual dysfunction in the elderly: age or disease?
M. E. Camacho (2005)
Urogenital complaints and female sexual dysfunction. Part 2.
Salim A. Wehbe (2010)
Sexual satisfaction in the elderly female population: A special focus on women with gynecologic pathology.
E. Ratner (2011)

This paper is referenced by
Sexuality in menopausal women
Salvatore Caruso (2016)
Middle-aged female sexual dysfunction and multimorbidity: a population-based study
Ana Lúcia Ribeiro Valadares (2016)
2016 IMS Recommendations on women’s midlife health and menopause hormone therapy
R. Baber (2016)
Evaluation of sexual dysfunction and female sexual dysfunction indicators in women with type 2 diabetes: a systematic review and meta-analysis
Elham Rahmanian (2019)
Analysis of the sexual behavior of elderly women treated at a gynecological outpatient clinic
L. R. Rodrigues (2018)
Sexual function and functioning of women in reproductive age
Jardelina Hermecina Dantas (2020)
Sex and Chronic Physical Illness
Marika J. Hess (2017)
Urine leakage during sexual activity among ethnically diverse, community‐dwelling middle‐aged and older women
Nagambika Munaganuru (2017)
Including Sexual Function in Patient Evaluation in the Rehabilitation Setting: Considerations for the Geriatric Population
Alexandra Turgeon Milspaw (2016)
Sexual Satisfaction and the Importance of Sexual Health to Quality of Life Throughout the Life Course of U.S. Adults.
K. Flynn (2016)
Effects of vilazodone on sexual functioning in healthy adults: results from a randomized, double-blind, placebo-controlled, and active-controlled study
Anita H. Clayton (2017)
The Effect of Chronic Musculoskeletal Pain on Sexual Function and Quality of Life of Cardiac Rehabilitation Patients
Pricilla Geraldine Wittkopf (2018)
Risk Factors for Sexual Dysfunction Among Women and Men: A Consensus Statement From the Fourth International Consultation on Sexual Medicine 2015.
M. McCabe (2016)
Factors associated with sexual health and well being in older adulthood
M. Kleinstäuber (2017)
Chronic Disease Burden, Sexual Frequency, and Sexual Dysfunction in Partnered Older Adults
Shannon Shen (2019)
Predictors of impact of vaginal symptoms in postmenopausal women
Mary M. Hunter (2016)
Medication Use and Sexual Function: A Population-Based Study in Middle Aged Women.
Anna Valéria Gueldini de Moraes (2019)
A Longitudinal Study of Sexual Function in Women With Newly Diagnosed Inflammatory Bowel Disease.
E. Shmidt (2019)
Blood Pressure, Sexual Activity, and Dysfunction in Women With Hypertension: Baseline Findings From the Systolic Blood Pressure Intervention Trial (SPRINT).
C. Foy (2016)
Women's Sexual Health and Aging.
Lisa Granville (2018)
Semantic Scholar Logo Some data provided by SemanticScholar