Online citations, reference lists, and bibliographies.
Please confirm you are human
(Sign Up for free to never see this)
← Back to Search

BRAF V600E Analysis For The Differentiation Of Papillary Craniopharyngiomas And Rathke's Cleft Cysts

L. Schweizer, D. Capper, A. Hoelsken, R. Fahlbusch, J. Flitsch, M. Buchfelder, C. Herold-Mende, A. Deimling, R. Buslei
Published 2015 · Biology, Medicine

Save to my Library
Download PDF
Analyze on Scholarcy
Share
The differential diagnosis of cystic epithelial masses of the sellar region, especially the histopathological differentiation of craniopharyngiomas and Rathke's cleft cysts, poses a challenge even to experienced diagnosticians. Recently, BRAF V600E mutations have been described as a genetic hallmark of papillary craniopharyngiomas. We investigated a series of 33 Rathke's cleft cysts to determine the frequency of BRAF V600E mutations and its suitability as an additional diagnostic marker for the differentiation of cystic lesions of the sellar region.
This paper references
10.1007/s00401-013-1118-5
VE1 immunohistochemistry in pituitary adenomas is not associated with BRAF V600E mutation
J. Sperveslage (2013)
10.1007/s00701-009-0448-5
Ciliated craniopharyngioma—case report and pathological study
Tomu Okada (2009)
10.1007/s00701-011-1072-8
Prognostic factors of operated Rathke’s cleft cysts with special reference to re-accumulation and recommended surgical strategy
Y. Ogawa (2011)
10.1097/01.pas.0000213328.64121.12
Nuclear β-Catenin Accumulation as Reliable Marker for the Differentiation Between Cystic Craniopharyngiomas and Rathke Cleft Cysts: A Clinico-Pathologic Approach
B. Hofmann (2006)
10.3171/2010.2.FOCUS09318
Craniopharyngioma and other cystic epithelial lesions of the sellar region: a review of clinical, imaging, and histopathological relationships.
G. Zada (2010)
10.2353/jmoldx.2010.090188
Comparison of Sanger sequencing, pyrosequencing, and melting curve analysis for the detection of KRAS mutations: diagnostic and clinical implications.
Athanasios C Tsiatis (2010)
10.1016/j.critrevonc.2013.12.008
BRAF inhibitors: From the laboratory to clinical trials.
M. A. Rahman (2014)
10.1007/s00401-005-1004-x
Common mutations of β-catenin in adamantinomatous craniopharyngiomas but not in other tumours originating from the sellar region
R. Buslei (2005)
10.1038/ng.2868
Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas
P. Brastianos (2014)
10.1007/BF00688754
Ciliated and goblet cells in craniopharyngioma
T. Matsushima (2004)
Comparison of Sanger sequencing, pyrosequencing, and melting curve analysis BRAF V600E analysis in Rathke's cleft cysts 741
A C Tsiatis (2010)
10.3171/JNS.2005.102.2.0189
Surgical outcomes in 118 patients with Rathke cleft cysts.
Christopher J Aho (2005)
10.1007/s00401-011-0841-z
Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody
D. Capper (2011)
10.1007/s00401-014-1270-6
BRAF V600E mutations are characteristic for papillary craniopharyngioma and may coexist with CTNNB1-mutated adamantinomatous craniopharyngioma
Sarah J. Larkin (2014)
10.1007/s00701-012-1593-9
Rathke’s cleft cysts with significant squamous metaplasia—high risk of postoperative deterioration and close origins to craniopharyngioma
Y. Ogawa (2012)
10.1007/s00401-007-0243-4
The 2007 WHO Classification of Tumours of the Central Nervous System
D. N. Louis (2007)
10.1016/j.humpath.2012.07.010
Detection of the BRAF V600E mutation in serous ovarian tumors: a comparative analysis of immunohistochemistry with a mutation-specific monoclonal antibody and allele-specific PCR.
H. Boesmueller (2013)
Detection of the BRAF V 600 E mutation in serous ovarian tumors : a comparative analysis of immunohistochemistry with a mutation - specific monoclonal antibody and allele - specific PCR
H Bosmuller
10.1007/s00401-013-1100-2
Mutant BRAF V600E protein in ganglioglioma is predominantly expressed by neuronal tumor cells
C. Koelsche (2013)
10.3171/2009.10.JNS091265
A Rathke cleft cyst to craniopharyngioma: is there a spectrum?
S. Wolfe (2010)
10.1016/j.jmoldx.2010.11.005
Detection of KRAS and BRAF mutations in colorectal carcinoma roles for high-sensitivity locked nucleic acid-PCR sequencing and broad-spectrum mass spectrometry genotyping.
M. Arcila (2011)
10.3171/JNS.2004.100.1.0033
Surgical treatment of symptomatic Rathke cleft cysts: clinical features and results with special attention to recurrence.
J. E. Kim (2004)



This paper is referenced by
10.3389/fgene.2018.00049
Rathke's Cleft Cyst as Origin of a Pediatric Papillary Craniopharyngioma
Sven-Martin Schlaffer (2018)
10.11452/NEUROONCOLOGY.23.1_35
Clinicopathological features of craniopharyngioma and the endoscopic endonasal surgery
H. Nishioka (2016)
10.18632/oncotarget.10501
TREM-1 expression in craniopharyngioma and Rathke's cleft cyst: its possible implication for controversial pathology
Y. Liu (2016)
10.1111/nan.12397
WHO 2016 classification: changes and advancements in the diagnosis of miscellaneous primary CNS tumours
F. Sahm (2018)
10.1111/neup.12408
High‐resolution melting and immunohistochemical analysis efficiently detects mutually exclusive genetic alterations of adamantinomatous and papillary craniopharyngiomas
K. Yoshimoto (2018)
10.1007/s11102-018-0909-z
BRAF V600E mutant papillary craniopharyngiomas: a single-institutional case series
Emanuele La Corte (2018)
10.1007/978-3-319-56691-7_9
Classification, Pathobiology, Molecular Markers, and Intraoperative Pathology
M. B. Lopes (2017)
10.5603/EP.2018.0023
Cystic lesions of the sellar-suprasellar region - diagnosis and treatment.
E. Andrysiak-Mamos (2018)
10.1186/s40478-016-0287-6
Adamantinomatous and papillary craniopharyngiomas are characterized by distinct epigenomic as well as mutational and transcriptomic profiles
A. Hoelsken (2016)
10.1016/j.jchemneu.2018.10.005
Effects of craniopharyngioma cyst fluid on neurons and glial cells cultured from rat brain hypothalamus
Mausam Ghosh (2018)
10.1093/annonc/mdz164
Molecular pathology of tumors of the central nervous system
B. R. Kristensen (2019)
10.1093/jnen/nlw116
Genomic Alterations of Adamantinomatous and Papillary Craniopharyngioma
T. Goschzik (2017)
10.3171/2017.4.JNS163113
Prediction of BRAF mutation status of craniopharyngioma using magnetic resonance imaging features.
Qi Yue (2018)
10.1017/cjn.2019.314
Papillary Craniopharyngioma in a Young Child: The Importance of BRAF Mutational Testing.
S. Magaki (2019)
10.1007/978-3-319-52619-5_7-1
Radiation Therapy in Craniopharyngioma
C. Seidel (2018)
10.1007/978-3-030-41176-3_1
Histopathology and Molecular Pathology of Craniopharyngioma in Adults
Alexandre Vasiljevic (2020)
10.1007/978-1-4614-8429-5_18
Benign Cystic Lesions
C. Lacruz (2014)
10.1055/a-1217-7282
Revived Attention for Adult Craniopharyngioma.
K. C. Mende (2020)
10.1007/978-3-319-51890-9_1
Pathogenesis of Human ACP
A. Hoelsken (2017)
10.1111/nan.12246
Diagnostic, prognostic and predictive relevance of molecular markers in gliomas
S. Brandner (2015)
10.1097/MED.0000000000000214
Craniopharyngioma and hypothalamic injury: latest insights into consequent eating disorders and obesity
H. Müller (2016)
10.1007/978-3-030-41176-3
Adult Craniopharyngiomas: Differences and Lessons from Paediatrics
Emmanuel Jouanneau (2020)
10.3171/2016.9.FOCUS16308
Potential evolution of neurosurgical treatment paradigms for craniopharyngioma based on genomic and transcriptomic characteristics.
Leslie C. Robinson (2016)
10.1007/s11102-015-0669-y
Targeted BRAF and CTNNB1 next-generation sequencing allows proper classification of nonadenomatous lesions of the sellar region in samples with limiting amounts of lesional cells
G. Marucci (2015)
10.1038/srep29731
EpCAM (CD326) is differentially expressed in craniopharyngioma subtypes and Rathke’s cleft cysts
V. Thimsen (2016)
10.1007/s11102-018-0890-6
Can tissue biomarkers reliably predict the biological behavior of craniopharyngiomas? A comprehensive overview
R. Prieto (2018)
10.1007/s11060-017-2465-1
Study of β-catenin and BRAF alterations in adamantinomatous and papillary craniopharyngiomas: mutation analysis with immunohistochemical correlation in 54 cases
P. Malgulwar (2017)
10.4172/2161-0681.1000291
Brafv600e and Ctbn1 Mutational Study in Rathke's Cleft Cysts
M. Antonelli (2016)
10.5772/INTECHOPEN.74512
Modern Management of Craniopharyngioma
Anirudh Penumaka and Ekkehard Kasper (2018)
10.1172/jci136745
Rathke's cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors.
M. Brinkmeier (2020)
10.1007/s00381-018-3925-4
Papillary craniopharyngioma in a 4-year-old girl with BRAF V600E mutation: a case report and review of the literature
R. Borrill (2018)
10.1007/978-3-030-41176-3_11
Adult Versus Paediatric Craniopharyngiomas: Which Differences?
K. Sweeney (2020)
See more
Semantic Scholar Logo Some data provided by SemanticScholar