Online citations, reference lists, and bibliographies.
← Back to Search

Use Of Reflectance Near-infrared Spectroscopy To Investigate The Effects Of Daily Moisturizer Application On Skin Optical Response And Barrier Function.

M. Qassem, P. Kyriacou
Published 2014 · Medicine

Cite This
Download PDF
Analyze on Scholarcy
Share
A number of noninvasive techniques and instruments have emerged over the years allowing much progress toward clarifying the structure and function of human skin and studying the effects of various applied substances. All of this research has provided great insight into the interactions between skin and various products through quantitative and qualitative measurements. Such methods include near-infrared spectroscopy (NIRS), a technique which has gained popularity over the years and has often been employed to accurately determine the moisture levels and water content of skin based on its sensitivity to hydrogen bonding. NIRS has also been applied in many studies to report the efficacy of moisturizing products and assess their benefits to the skin. However, many of these studies have reported an increase in skin water content following moisturizer application while some have challenged the benefits of long-term moisturizer use, particularly on normal skin, and even suggested that it can increase the skin's susceptibility to irritants. This paper reports the results of a pilot in vivo study carried out on the skin of 20 healthy volunteers, categorized into groups depending on their skin type and frequency of moisturizer use, in order to investigate the optical response of human skin after direct short-term contact with water followed by application of a moisturizer. The measurements were obtained using a highly advanced spectrophotometer in the region of 900 to 2100 nm equipped with a customized reflectance fiber optic handheld probe. Scatter graphs of group results and second derivative spectra have shown an interesting pattern between frequent users of moisturizers and individuals who do not use moisturizers, suggesting that long-term daily moisturization may have an effect on skin barrier function. The results also raise some questions regarding the optical characteristics of different skin types, as well as the varying response between different water bands in the NIR region. Future work will focus on gaining more knowledge about these subjects and obtaining results from a larger population, as well as performing statistical analysis through regression methods in order to further improve optical skin measurements.
This paper references
10.1097/01.WON.0000308623.68582.d7
The Effect of Washing and Drying Practices on Skin Barrier Function
D. Voegeli (2008)
10.1366/00037020360626032
Determining Water Content in Human Nails with a Portable Near-Infrared Spectrometer
M. Egawa (2003)
Moisturizers: what they are and how they work.
L. Cw (2001)
10.1007/s11517-008-0343-x
Characterization of healthy skin using near infrared spectroscopy and skin impedance
I. Bodén (2008)
10.1111/srt.12024
Comparing the rates of absorption and weight loss during a desorption test using near infrared spectroscopy
M. Qassem (2013)
Determini ng water content in human nails with a portable near-infrared spectrometer,
M. Egawa (2003)
10.1109/EMBC.2012.6347372
In vitro spectrophotometric near infrared measurements of skin absorption and dehydration
Meha Qassem (2012)
what they are and how they work,” Skin Therapy Lett
C. W. Lynde (2001)
Moisturizers: what they are and how they work.
C. Lynde (2001)
10.1046/J.1523-1747.1999.00774.X
Water disrupts stratum corneum lipid lamellae: damage is similar to surfactants.
R. R. Warner (1999)
10.1111/j.1600-0846.2009.00353.x
In vivo simultaneous measurement of urea and water in the human stratum corneum by diffuse‐reflectance near‐infrared spectroscopy
M. Egawa (2009)
10.1159/000241298
Stratum Corneum Damage and ex vivo Porcine Skin Water Absorption – A Pilot Study
C. Duch Lynggaard (2009)
a review on its molecular mechanisms,” J
S. Verdier-Sévrain (2007)
Use of reflectance near-infrared spectroscopy to investigate the effects
M. Mohamad (2011)
10.1111/j.1600-0536.1997.tb00213.x
Barrier recovery and influence of irritant stimuli in skin treated with a moisturizing cream
M. Lodén (1997)
10.1111/j.1365-2133.2006.07685.x
Changes in skin barrier function following long‐term treatment with moisturizers, a randomized controlled trial
I. Buraczewska (2007)
10.1080/00015550152384227
Effect of moisturizers on skin susceptibility to irritants.
E. Held (2001)
10.1111/j.1600-0846.2005.00093.x
Depth profile of diffuse reflectance near‐infrared spectroscopy for measurement of water content in skin
H. Arimoto (2005)
10.1007/978-3-642-27606-4
Treatment of dry skin syndrome
M. Lodén (2012)
consideration of measurement depth,” Appl
M. Egawa et al. (2006)
Treatment of Dry Skin Syndrome: The Art and Science of Moisturizers
H. Maibach (2012)
10.1366/0003702042641218
Non-Contact Skin Moisture Measurement Based on Near-Infrared Spectroscopy
H. Arimoto (2004)
10.1046/J.1523-1747.2003.12046.X
Hydration disrupts human stratum corneum ultrastructure.
R. R. Warner (2003)
10.1111/j.1473-2165.2007.00300.x
Skin hydration: a review on its molecular mechanisms
S. Verdier-Sévrain (2007)
and M
H. Arimot (2003)
10.1366/000370206775382866
Regional Difference of Water Content in Human Skin Studied by Diffuse-Reflectance Near-Infrared Spectroscopy: Consideration of Measurement Depth
M. Egawa (2006)
10.1080/000155599750011705
Effect of long-term use of moisturizer on skin hydration, barrier function and susceptibility to irritants.
E. Held (1999)
10.1109/IEMBS.2003.1280885
Skin moisture measurement based on near-infrared spectroscopy and regression analysis
H. Arimoto (2003)
10.1109/EMBC.2013.6610020
In vivo optical investigation of short term skin water contact and moisturizer application using NIR spectroscopy
Meha Qassem (2013)
damage is similar to surfactants,” J
R. R. Warner et al. (1999)
10.1109/CHUSER.2011.6163846
Conceptual design of near infrared spectroscopy instrumentation for skin moisture measurement
M. Mohamad (2011)
10.1201/9781420016123
Surfactants in Personal Care Products and Decorative Cosmetics
L. D. Rhein (2006)
10.1021/AC0102563
Development of a method for the determination of human skin moisture using a portable near-infrared system.
Y. A. Woo (2001)
10.5772/26420
Optical Fiber Near Infrared Spectroscopy for Skin Moisture Measurement
A. Omar (2012)
and P
M. Qasse (2012)
10.1111/J.1467-2494.2006.00314_4.X
Ability of moisturizers to reduce dry skin and irritation and to prevent their return.
F. Simion (2005)
Direct measurement of moisture in skin by NIR spectroscopy
K. Martin (1993)
10.2165/00128071-200304110-00005
Role of Topical Emollients and Moisturizers in the Treatment of Dry Skin Barrier Disorders
M. Lodén (2003)
Moisture in skin by near-infrared reflectance spectroscopy
P. Walling (1989)
10.1111/j.1365-2133.2008.08703.x
Measuring the effects of topical moisturizers on changes in stratum corneum thickness, water gradients and hydration in vivo
J. Crowther (2008)
10.1111/j.1600-0846.2008.00331.x
Assessment of moisturizers and barrier function restoration using dynamic methods
C. Rosado (2009)
10.1111/j.1396-0296.2004.04S1005.x
Moisturization and skin barrier function
A. V. Rawlings (2004)
Bonté, “Skin hydration: a re view on its molecular mechanisms,
F. S. Verdier-Sévrain (2007)
NIR for the study of human skin,
J. W. Wiechers (2004)
10.1111/j.1600-0536.1999.tb06990.x
How irritant is water? An overview
T. Tsai (1999)



This paper is referenced by
Semantic Scholar Logo Some data provided by SemanticScholar