Online citations, reference lists, and bibliographies.
← Back to Search

Phospholipase D: A Downstream Effector Of ARF In Granulocytes.

S. Cockcroft, G. Thomas, A. Fensome, B. Geny, E. Cunningham, I. Gout, I. Hiles, N. Totty, O. Truong, J. Hsuan
Published 1994 · Biology, Medicine

Save to my Library
Download PDF
Analyze on Scholarcy
Share
Activation of the phospholipase D (PLD) pathway is a widespread response when cells are activated by agonists that bind receptors on the cell surface. A 16-kD cytosolic component can reconstitute guanosine triphosphate (GTP)-mediated activation of phospholipase D in HL60 cells depleted of their cytosol by permeabilization. This factor was purified and identified as two small GTP-binding proteins, ARF1 and ARF3. Recombinant ARF1 substituted for purified ARF proteins in the reconstitution assay. These results indicate that phospholipase D is a downstream effector of ARF1 and ARF3. The well-established role of ARF in vesicular traffic would suggest that alterations in lipid content by PLD are an important determinant in vesicular dynamics.
This paper references
Evidence for ADP-ribosylation factor (ARF) as a regulator of in vitro endosome-endosome fusion.
J. Lenhard (1992)
10.1182/BLOOD.V77.12.2746.2746
Diacylglycerol generation in fluoride-treated neutrophils: involvement of phospholipase D.
Denis English (1991)
10.1038/355409A0
Molecular dissection of the secretory pathway
J. Rothman (1992)
Purification of a protein cofactor required for ADP-ribosylation of the stimulatory regulatory component of adenylate cyclase by cholera toxin.
R. Kahn (1984)
10.1016/0014-5793(91)80160-5
Activation of phospholipase D in rabbit neutrophils by fMet‐Leu‐Phe is mediated by a pertussis toxin‐sensitive GTP‐binding protein that may be distinct from a phospholipase C‐regulating protein
Y. Kanaho (1991)
10.1016/S0006-291X(05)81225-2
Granulocyte phospholipase D is activated by a guanine nucleotide dependent protein factor.
J. Anthes (1991)
10.1073/PNAS.89.19.9272
Differential interaction of ADP-ribosylation factors 1, 3, and 5 with rat brain Golgi membranes.
S. C. Tsai (1992)
Stimulation of choleragen enzymatic activities by GTP and two soluble proteins purified from bovine brain.
S. C. Tsai (1988)
Phospholipase D activation in a cell-free system from human neutrophils by phorbol 12-myristate 13-acetate and guanosine 5'-O-(3-thiotriphosphate). Activation is calcium dependent and requires protein factors in both the plasma membrane and cytosol.
S. Olson (1991)
Phospholipase D catalyzes phospholipid metabolism in chemotactic peptide-stimulated HL-60 granulocytes.
J. Pai (1988)
10.1016/0960-9822(92)90276-G
From G minor to G major
W. Balch (1992)
10.1111/J.1432-1033.1993.TB18045.X
Rat brain cytosol contains a factor which reconstitutes guanine-nucleotide-binding-protein-regulated phospholipase-D activation in HL60 cells previously permeabilized with streptolysin O.
B. Geny (1993)
10.1073/PNAS.89.14.6408
ADP-ribosylation factor, a small GTP-binding protein, is required for binding of the coatomer protein beta-COP to Golgi membranes.
J. Donaldson (1992)
Transphosphatidylation by phospholipase D.
S. Yang (1967)
10.1016/0092-8674(89)90872-6
Fatty acyl-coenzyme a is required for budding of transport vesicles from Golgi cisternae
N. Pfanner (1989)
10.1016/0962-8924(91)90067-J
Phospholipid transfer proteins: a biological debut.
A. Cleves (1991)
Fluoride is not an activator of the smaller (20-25 kDa) GTP-binding proteins.
R. Kahn (1991)
10.1016/0076-6879(92)19036-6
Preparation of recombinant ADP-ribosylation factor.
P. Randazzo (1992)
Neutrophil phospholipase D is activated by a membrane-associated Rho family small molecular weight GTP-binding protein.
E. P. Bowman (1993)
10.1038/364818A0
Receptor and protein kinase C-mediated regulation of ARF binding to the Golgi complex
M. A. Matteis (1993)
10.1016/0092-8674(93)90471-2
An essential role for phosphatidylinositol transfer protein in phospholipase C-Mediated inositol lipid signaling
G. Thomas (1993)
10.1038/358512A0
A role for ADP-ribosylation factor in nuclear vesicle dynamics
A. Boman (1992)
Molecular identification of ADP-ribosylation factor mRNAs and their expression in mammalian cells.
M. Tsuchiya (1991)
10.1016/0092-8674(91)90176-Y
ADP-Ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: A novel role for a GTP-binding protein
T. Serafini (1991)
10.1073/PNAS.85.13.4620
Sequences of the bovine and yeast ADP-ribosylation factor and comparison to other GTP-binding proteins.
J. L. Sewell (1988)



This paper is referenced by
10.1073/PNAS.94.24.12926
Cloning and expression of a cDNA encoding a bovine brain brefeldin A-sensitive guanine nucleotide-exchange protein for ADP-ribosylation factor.
N. Morinaga (1997)
10.1523/JNEUROSCI.18-15-05594.1998
An Essential Role for a Small Synaptic Vesicle-Associated Phosphatidylinositol 4-Kinase in Neurotransmitter Release
C. Wiedemann (1998)
10.1007/978-1-4419-8740-2_22
Activation of toxin ADP-ribosyltransferases by eukaryotic ADP-ribosylation factors
J. Moss (1999)
10.1016/S0171-2985(96)80042-8
Brefeldin A inhibits antigen- or calcium ionophore-mediated but not PMA-induced phospholipase D activation in rat basophilic leukemia (RBL-2H3) cells.
Y. Nakamura (1996)
Discovery of small molecule modulators of Ras superfamily proteins : Studies of MgcRacGAP and Ras
Arjan J. van Adrichem (2016)
10.1091/MBC.01-05-0245
ARL2 and BART enter mitochondria and bind the adenine nucleotide transporter.
J. Sharer (2002)
10.1016/j.bbalip.2009.03.013
Emerging findings from studies of phospholipase D in model organisms (and a short update on phosphatidic acid effectors).
P. Raghu (2009)
10.1126/science.270.5244.1999
The ARF1 GTPase-Activating Protein: Zinc Finger Motif and Golgi Complex Localization
E. Cukierman (1995)
10.1074/JBC.271.8.4504
Regulation of Phospholipase D by Protein Kinase C Is Synergistic with ADP-ribosylation Factor and Independent of Protein Kinase Activity (*)
W. D. Singer (1996)
10.1007/BF00238002
Molecular mechanisms in exocytosis
J. Edwardson (2004)
10.1016/j.bbalip.2009.05.011
Phospholipase D in endocytosis and endosomal recycling pathways.
Julie G Donaldson (2009)
10.1073/PNAS.95.14.7909
Solution structure of the cytohesin-1 (B2-1) Sec7 domain and its interaction with the GTPase ADP ribosylation factor 1.
S. Betz (1998)
10.1111/j.1476-5381.1995.tb16416.x
Mastoparan‐induced phosphatidylcholine hydrolysis by phospholipase D activation in human astrocytoma cells
K. Mizuno (1995)
10.1002/1873-3468.13808
Structural characterization of an Arf dimer interface: molecular mechanism of Arf‐dependent membrane scission
P. Diestelkoetter-Bachert (2020)
10.1074/jbc.M113.481101
Recruitment of the Mint3 Adaptor Is Necessary for Export of the Amyloid Precursor Protein (APP) from the Golgi Complex*
Amanda H. Caster (2013)
10.1083/jcb.201303067
JAK tyrosine kinases promote hierarchical activation of Rho and Rap modules of integrin activation
A. Montresor (2013)
10.1371/journal.pone.0184575
ARF6 mediates nephrin tyrosine phosphorylation-induced podocyte cellular dynamics
J. Lin (2017)
10.1242/jcs.01090
The GDP-bound form of Arf6 is located at the plasma membrane
E. Macía (2004)
10.1083/JCB.148.1.137
Potentiation of Fc∈ Receptor I–Activated Ca2+ Current (ICRAC) by Cholera Toxin
M. McCloskey (2000)
10.1007/PL00000805
Signalling roles of mammalian phospholipase D1 and D2
S. Cockcroft (2001)
10.1074/jbc.M108353200
TAPAS-1, a Novel Microdomain within the Unique N-terminal Region of the PDE4A1 cAMP-specific Phosphodiesterase That Allows Rapid, Ca2+-triggered Membrane Association with Selectivity for Interaction with Phosphatidic Acid*
G. Baillie (2002)
10.1139/O04-113
Regulation of G protein-coupled receptor endocytosis by ARF6 GTP-binding proteins.
A. Claing (2004)
10.18632/oncotarget.9405
ARF1 promotes prostate tumorigenesis via targeting oncogenic MAPK signaling
J. E. Davis (2016)
10.1007/s004180050249
Biosynthetic protein transport through the early secretory pathway
W. Nickel (1998)
10.1126/science.272.5259.227
Protein Sorting by Transport Vesicles
J. Rothman (1996)
10.1016/0009-3084(96)02546-7
ARF-regulated phospholipase D: a potential role in membrane traffic.
S. Cockcroft (1996)
10.1007/978-3-662-22022-1_4
ROLE OF PHOSPHOLIPASES, PROTEIN KINASES AND CALCIUM IN FcERI- INDUCED SECRETION
M. Beaven (1997)
10.1096/fasebj.10.5.8621061
The Ras superfamily of GTPases 1
I. Macara (1996)
10.1016/S0005-2760(97)00083-0
Phorbol myristate acetate-dependent association of protein kinase C alpha with phospholipase D1 in intact cells.
T. Lee (1997)
10.1007/978-1-4419-8632-0_41
Activation of toxin ADP-ribosyltransferases by the family of ADP-ribosylation factors.
M. Vaughan (1997)
10.1006/BBRC.1997.6793
RalA interacts directly with the Arf-responsive, PIP2-dependent phospholipase D1.
J. Luo (1997)
10.1074/jbc.273.21.12846
Cloning and Initial Characterization of a Human Phospholipase D2 (hPLD2)
I. López (1998)
See more
Semantic Scholar Logo Some data provided by SemanticScholar