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Oral Treatment With Lactococcus Lactis Expressing Staphylococcus Hyicus Lipase Enhances Lipid Digestion In Pigs With Induced Pancreatic Insufficiency

Sophie Drouault, Catherine Juste, Philippe Marteau, Pierre Renault, Gérard Corthier

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ABSTRACT The Staphylococcus hyicus lip gene was cloned in Lactococcus lactis . Pancreatic insufficiency was induced by ligation of the pancreatic duct in pigs. In pigs who had undergone pancreatic ligation, the coefficient of fat absorption was higher after consumption of lipase-expressing L. lactis (91.9% ± 3.7%) than that after consumption of the inactive control strain (78.4% ± 2.4%).