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Horizontal Gene Transfer Is The Main Driver Of Antimicrobial Resistance In Broiler Chicks Infected With Salmonella Enterica Serovar Heidelberg

Adelumola Oladeinde, Zaid Abdo, Maximilian O. Press, Kimberly Cook, Nelson A. Cox, Benjamin Zwirzitz, Reed Woyda, Steven M. Lakin, Jesse C. Thomas, Torey Looft, Douglas E. Cosby, Arthur Hinton, Jean Guard, Eric Line, Michael J. Rothrock, Mark E. Berrang, Kyler Herrington, Gregory Zock, Jodie Plumblee Lawrence, Denice Cudnik, Sandra House, Kimberly Ingram, Leah Lariscy, Martin Wagner, Samuel E. Aggrey, Lilong Chai, Casey Ritz

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The reported increase in antibiotic-resistant bacteria in humans has resulted in a major shift away from antibiotic use in food animal production. This shift has been driven by the assumption that removing antibiotics will select for antibiotic susceptible bacterial taxa, which in turn will allow the currently available antibiotic arsenal to be more effective.