Online citations, reference lists, and bibliographies.
← Back to Search

Comparative Study Of Chemical Composition And Antitumor Activity Of Aqueous-ethanol Extracts Of Brown Algae Laminaria Cichorioides, Costaria Costata, And Fucus Evanescens

T. Imbs, N. Krasovskaya, S. Ermakova, T. Makarieva, N. Shevchenko, T. Zvyagintseva
Published 2009 · Biology

Cite This
Download PDF
Analyze on Scholarcy
The chemical composition of water-ethanol extracts of the brown algae Laminaria cichorioides, Costaria costata, and Fucus evanescens were studied. The extracts contained mannitol, iodine, micro elements, free amino acids, glycolipids, polyunsaturated fatty acids, fucosterine, and polyphenols. The extracts were distinguished by high contents of mannitol and iodine (L. cichorioides), lipophilic matter (C. costata), and polyphenol compounds (F. evanescens). All the extracts under study inhibited the growth of DLD-1 and HT-29 human intestine tumor cells. The strongest inhibitory effect was exerted by the extract of F. evanescens at a concentration of 50 μg/ml. The extracts can be recommended for the production of fucosterol, phlorotannins, chlorophyll derivatives, mannitol, and compositions for medical and veterinary application.
This paper references
Annotirovannyi spisok vodoroslei-makrofitov severnogo Primorya (Annotated List of Macrophyte Algae of the Northern Primorye)
I. S. Gusarova (2000)
Quantitative determination of formaldehyde liberated with periodate oxidation.
V. E. Vaskovsky (1969)
Sterols from Six Marine Sponges , Biochem
E. A. Santalova (2004)
Nastoiki, ekstrakty, eliksiry i ikh stadartizatsiya (Tincture, Extracts, Elixirs, and Their Stadardization)
V. L. Bagirova (2001)
The Effect of Mineral Iodine and Iodine of Food Plant Origin upon the Thyroid Gland, Problemy patologii v experimente i v klinike (Problems of Pathology in Experiment and in Clinic)
I. V. Kovtun (1974)
Specific interaction between an oligosaccharide on the tumor cell surface and the novel antitumor agents, sulfoquinovosylacylglycerols.
K. Ohta (2001)
Specific Interaction Between an Oligosaccharide on the Tumor Cell Surface and the Novel Antitumor Agents , Sulfoquinovosylacylglycerols , Biochem
K. Ohta (2001)
Sterols from six marine sponges
E. A. Santalova (2004)
Application of Fatty Acids for Chemotaxonomy of Reef-Building Corals
A. B. Imbs (2007)
Lipidy morskikh vodoroslei-makrofitov i trav. Struktura, raspredelenie, analiz (Lipids of Sea Macrophytic Algae and Grasses
S. V. Khotimchenko (2003)
Colorimetric method for determination of sugars and related substances
Michel. DuBois (1956)
A new procedure for the separation of water-soluble polysaccharides from brown seaweeds
T. Zvyagintseva (1999)
Antioxidant activity of phlorotannins isolated from the brown alga Eisenia bicyclis
T. Nakamura (1996)
Annotirovannyi spisok vodorosleimakrofitov severnogo Primorya ( Annotated List of Macrophyte Algae of the Northern Primorye ) , Izv
I. S. Gusarova (2000)
Cardioprotective Action of Taurin, Eksperimentalnaya i klinicheskaya farmakologiya (Experimental and Clinical Pharmacology)
P. A. Tolkunov (1997)
Seaweed Prevents Breast Cancer?
H. Funahashi (2001)
Biokhimiya syr’ya vodnogo proiskhozhdeniya (Biochemitry of Raw Materials of Aquatic Origin)
I. V. Kizevetter (1973)
Protein measurement with the Folin phenol reagent.
O. H. Lowry (1951)
Metally i galogeny v morskikh organizmakh (Metals and Halogens in Marine Organisms)
G. N. Saenko (1992)
Pererabotka morskikh vodoroslei i drugikh promyslovykh vodnykh rastenii (Products from Marine Algae and Other Commercial Aquatic Plants), Moscow
I. V. Kizevetter (1967)
Comparison of three methods for quantifying brown algal polyphenolic compounds
K. L. V. Alstyne (2005)
Antitumor and antimetastatic activity of fucoidan, a sulfated polysaccharide isolated from the Okhotsk sea Fucus evanescens brown alga
T. V. Alekseyenko (2007)
Carotenoids affect proliferation of human prostate cancer cells.
E. Kotake-Nara (2001)
Seasonal Variation in Chemistry Components from Laminaria religiosa, Jpn
K. Matsuyama (1982)
[Algae polysaccharides. 55. Polysaccharide composition of some brown Kamchatka algae].
A. Usov (2001)
Vodorosli kamchatskogo shelfa. Rasprostranenie, biologiya, khimicheskii sostav (Seaweeds of Kamchatka Shelf. Distribution, Biology, Chemical Composition)
N. G. Klochkova (1997)
Sravnitel’naya biokhimiya vodoroslei (Comparative Biochemistry of Seaweeds)
G. K. Barashkov (1972)
Phlorotannins, brown algal polyphenols
M. Ragan (1986)
Seasonal Variation in Chemistry Components from Laminaria religiosa
K. Matsuyama (1982)
Seasonal variation in the lipid content of culturedLaminaria japonica: fatty acids, sterols, β-carotene and tocopherol
M. Honya (2004)
Chemical Composition and Exploitation of Brown Algae of the Far East Coast, Europ. Meeting: Marine Phytobenthos
A. V. Podkorytova (1990)
Atomno-absorbtsionnyi analiz (Atom-Absorption Analysis), Leningrad: Khimiya
I. Khavezov (1983)
Dissociation of mitogenesis and late-stage promotion of tumor cell phenotype by phorbol esters: mitogen-resistant variants are sensitive to promotion.
N. Colburn (1981)
Hypothesis: Iodine, selenium and the development of breast cancer
S. A. Cann (2004)
Chemical Species of Iodine in Some Seaweeds II. Iodine-Bound Biological Macromolecules
X. Hou (2000)
Application of Mediatory Amino Acids (Taurin) in the Ambulatory Gerontological Praxis, Sotsialnaya i klinicheskaya psikhiatriya (Social and Clinical Psychiatry)
Orudzhev (1998)
Chemical Composition of Extracts Containing Iodine and Other Biologically Active Components of Brown Algae , Materialy 2 mezhdunarod . konf
T. I. Vishnevskaya (2005)
Colorimetric Method for Determination of Sugars and Related Substances
M. DuBois (1956)

This paper is referenced by
Determination of the Season- al Yields of Total Fucose andFucoidan Yields in Brown Sea- weeds (Order Fucales) Distrib- uted along the Coast of Urla(izmir, Turkey)
Gamze Turan (2017)
The Seasonal Growth Dynamics of Fucus distichus subsp. evanescens (C. Agardh) H.T. Powell, 1957 (Phaeophyceae: Fucales) in the Avacha Bay (Southeastern Kamchatka)
A. N. Kashutin (2019)
Extraction of sulfated polysaccharides by autohydrolysis of brown seaweed Fucus vesiculosus
Rosa M Rodríguez-Jasso (2012)
Fucoidans from Brown Alga Fucus evanescens: Structure and Biological Activity
R. V. Menshova (2016)
The Dietary Fiber Profile, Total Polyphenol Content, Functionality of Silvetia compressa and Ecklonia arborea, and Modifications Induced by High Hydrostatic Pressure Treatments
Mireya Tapia-Salazar (2019)
Protein content and amino acid profile in New Zealand Undaria pinnatifida
A. Zhou (2012)
Isolation of Fucoxanthin and Highly Unsaturated Monogalactosyldiacylglycerol from Brown Alga Fucus evanescens C Agardh and In Vitro Investigation of Their Antitumor Activity
T. Imbs (2013)
Polysaccharides and their depolymerized fragments from Costaria costata: Molecular weight and sulfation-dependent anticoagulant and FGF/FGFR signal activating activities.
Ningning Hou (2017)
Antibacterial properties of a glycolipid-rich extract and active principle from Nunavik collections of the macroalgae Fucus evanescens C. Agardh (Fucaceae)
Treyvaud AmiguetVirginie (2011)
Development of fermentation process for fungal fucoidanases production
Rosa M Rodríguez-Jasso (2012)
Avaliação da capacidade citotóxica de macroalgas da costa de Peniche (Portugal) em células tumorais humanas
Celso Alves (2011)
Seaweed Flora of the European North Atlantic and Mediterranean
Leonel Pereira (2015)
Antiobesity Effects of the Ethanol Extract of Laminaria japonica Areshoung in High-Fat-Diet-Induced Obese Rat
W. S. Jang (2013)
Nutraceutical Potential of Five Mexican Brown Seaweeds
Ana Rocío Múzquiz de la Garza (2019)
Phlorotannins are Polyphenolic Metabolites of Brown Algae
T. Imbs (2018)
Phycochemical Constituents and Biological Activities of Fucus spp.
M. D. Catarino (2018)
High cytotoxicity and anti-proliferative activity of algae extracts on an in vitro model of human hepatocellular carcinoma
Celso Alves (2016)
In Vitro Anticancer and Radiosensitizing Activities of Phlorethols from the Brown Alga Costaria costata
Olesya S Malyarenko (2020)
The Effects of the Lipid Complex of Extract from the Marine Red Alga Ahnfeltia tobuchiensis (Kanno et Matsubara) Makienko on the Biochemical Parameters of Blood Plasma and Erythrocyte Membranes during Experimental Stress Exposure
N. F. Kushnerova (2020)
Rhodobacteraceae on the marine brown alga Fucus spiralis are abundant and show physiological adaptation to an epiphytic lifestyle.
Marco Dogs (2017)
An extract from the brown alga Laminaria japonica: a promising stress-protective preparation
N. Kushnerova (2010)
The potential of seaweed as a source of drugs for use in cancer chemotherapy
C. Murphy (2014)
A kinetic assessment of glucose production from pretreated Gelidium amansii by dilute acid hydrolysis
T. Jeong (2012)
The Comparative Analysis of Antiviral Activity of Native and Modified Fucoidans from Brown Algae Fucus evanescens In Vitro and In Vivo
Natalya V Krylova (2020)
Indonesian Sargassum species bioprospecting: potential applications of bioactive compounds and challenge for sustainable development
M. Puspita (2020)
Seasonal changes in the content of lipids and photosynthetic pigments in a brown alga Saccharina cichorioides
N. Gerasimenko (2014)
The antioxidant and stress-protective properties of an extract from the green alga Ulva lactuca Linnaeus, 1753
S. Fomenko (2016)
Semantic Scholar Logo Some data provided by SemanticScholar