Online citations, reference lists, and bibliographies.

Primary Neuroendocrine Carcinoma Of The Brain

Clay T Reed, Narjust Duma, Thorvardur R Halfdanarson, Jan C. Buckner
Published 2019 · Medicine
Cite This
Download PDF
Analyze on Scholarcy
Neuroendocrine neoplasms (NENs) are malignancies with rare reports of central nervous system development. A 34-year-old woman was found to have a primary NEN of the brain, and she had recurrence with identical histology 10 years later. Extracranial NENs were excluded. She had routine surveillance for the first 5 years with MRIs and positron emission tomography/CTs after the initial presentation which was treated with radiation followed by cisplatin and etoposide. This case highlights the difference in primary NENs versus NEN metastases to the brain, and that longer periods of surveillance are likely required for primary NENs. This is important because the prognosis between primary NENs and metastatic NENs to the brain are vastly different and should not be treated as equal diseases. The patient eventually died of her recurrence secondary to complications of a ventriculoperitoneal shunt placed for treatment of hydrocephalus from the disease.
This paper references
The Pathologic Classification of Neuroendocrine Tumors: A Review of Nomenclature, Grading, and Staging Systems
David S Klimstra (2010)
Primary carcinoid tumor of the skull base: case report and review of the literature.
Mohannad Ibrahim (2010)
Primary Neuroendocrine Tumor in Brain
Ryota Tamura (2014)
Predilection of brain metastasis in gray and white matter junction and vascular border zones.
T L Hwang (1996)
Brain carcinoid metastases: outcomes and prognostic factors.
Grant W. Mallory (2013)
Molecular Neuropharmacology: A Foundation for Clinical Neuroscience
Eric J. Nestler (2001)
Imaging in neuroendocrine tumors: an update for the clinician.
Jessica E. Maxwell (2015)
ENETS Consensus Guidelines for the Management of Brain, Cardiac and Ovarian Metastases from Neuroendocrine Tumors
M. Pavel (2010)
Trends in the Incidence, Prevalence, and Survival Outcomes in Patients With Neuroendocrine Tumors in the United States
Arvind Dasari (2017)
Human Physiology
Li-Shan Chou (1999)
Neuroendocrine carcinoma of the pineal parenchyma. The first reported case
Melanie H Hakar (2017)
Carcinoids of unknown origin: comparative analysis with foregut, midgut, and hindgut carcinoids.
Paul M. Kirshbom (1998)
Exploring the rising incidence of neuroendocrine tumors: a population-based analysis of epidemiology, metastatic presentation, and outcomes.
Julie Hallet (2015)
The neuroendocrine system and its tumors: an overview.
Ronald A DeLellis (2001)
Carcinoid metastasis to the brain.
R. Hlatký (2004)
Primary carcinoid tumor of the cavernous sinus.
Brian J Hood (2014)
Intracranial carcinoid without evidence of extracranial disease.
David G. Porter (2000)
Human physiology. 15th edn
S I Fox (2019)
Clinicopathological analysis in patients with neuroendocrine tumors that metastasized to the brain
J. Akimoto (2015)
Thyroid transcription factor 1 in pulmonary adenocarcinoma
Grant Stenhouse (2004)
Primary intracranial neuroendocrine tumor: two case reports
H. Liu (2016)
A carcinoid tumor mimicking an isolated intracranial meningioma. Case report.
E. Deshaies (2004)
Neuroendocrine tumor epidemiology: contrasting Norway and North America.
Oyvind Hauso (2008)

This paper is referenced by
Semantic Scholar Logo Some data provided by SemanticScholar