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Relationship Between Glaucoma And Selenium Levels In Plasma And Aqueous Humour

R. Bruhn, W. Stamer, L. Herrygers, J. Levine, R. Noecker
Published 2008 · Medicine

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Aim: The aim of the study was to compare selenium levels in plasma and aqueous humour in subjects with and without primary open-angle glaucoma (POAG). Methods: Forty-seven POAG cases and 54 controls in this case–control study were recruited from surgery patients at the University Physician’s Ophthalmology Clinic in Tucson, Arizona, USA. Aqueous humour and plasma selenium were determined by high-performance liquid chromatography ion channel plasma mass spectrometry (HPLC ICP-MS). Potential confounders were assessed via a questionnaire. Biological samples were collected and processed at surgery and analysed for selenium content after collection was complete. Outcome measures included the odds of glaucoma in relationship to plasma selenium, aqueous humour selenium, and the ratio of levels of aqueous humour selenium to plasma selenium. Results: Tertile of selenium and its relationship to POAG was examined. After adjustment for common glaucoma risk factors, the odds of glaucoma in the highest tertile of plasma selenium (OR = 11.3; p = 0.03) and the middle tertile of aqueous humour selenium (OR = 0.06; p = 0.02) was significantly associated with glaucoma. Conclusion: Although a causal pathway cannot be inferred from our analysis, our data, added to that of others, suggest that the pathology is selenium-related.
This paper references
10.1016/1047-2797(91)90008-Z
Selenium, retinol, retinol-binding protein, and uric acid. Associations with cancer mortality in a population-based prospective case-control study.
M. Criqui (1991)
Selenium, retinol, retinolbinding protein, and uric acid. Associations with cancer mortality in a populationbased prospective case-control study
MH Criqui (1991)
10.1016/J.MAM.2005.07.004
Selenium, oxidative stress, and health aspects.
P. Brenneisen (2005)
Selenium in biomedicine
OH Muth (1967)
10.1097/00055735-200304000-00003
Ocular Hypertension Treatment Study (OHTS) commentary
B. L. Lee (2003)
10.1093/AJE/154.2.138
Is open-angle glaucoma associated with early menopause? The Rotterdam Study.
C. A. Hulsman (2001)
10.1016/S0039-6257(03)00006-7
Relationship between intraocular pressure and preservation of visual field in glaucoma.
I. Goldberg (2003)
10.1167/IOVS.02-0285
Female gender, estrogen loss, and Sub-RPE deposit formation in aged mice.
S. Cousins (2003)
10.1001/jama.1991.03470030069026
Racial variations in the prevalence of primary open-angle glaucoma. The Baltimore Eye Survey.
J. Tielsch (1991)
10.1006/EXER.1997.0458
Apoptosis and morphologic changes in drug-treated trabecular meshwork cells in vitro.
S. A. Sibayan (1998)
10.1016/S0272-2712(18)30143-4
The role of copper, molybdenum, selenium, and zinc in nutrition and health.
S. Chan (1998)
Family history and risk of primary open angle
status. J Glaucoma (1996)
10.1097/00006324-199304000-00003
The Glenn A. Fry Award Lecture 1992: aqueous humor proteins: a key for unlocking glaucoma?
T. Freddo (1993)
10.1093/AJCN/85.1.277S
Multivitamin-multimineral supplements: who uses them?
C. Rock (2007)
secretion by human trabecular meshwork cells
S Conley (2004)
10.1097/00055735-199804000-00009
Direct involvement of trabecular meshwork in the regulation of aqueous humor outflow
M. Wiederholt (1998)
seleniferous area in China. Part II: Relation between Se-intake and the manifestation of clinical signs and certain biochemical alterations in blood and urine
S Wang (1989)
Does sex matter in glaucoma?[comment
EJ Higginbotham (2004)
10.1167/IOVS.03-0767
Selenium's effects on MMP-2 and TIMP-1 secretion by human trabecular meshwork cells.
Shannon M Conley (2004)
Superoxide dismutase in ocular structures.
N. Rao (1985)
Selenium and selenomethionine
selenium. Biochem Pharmacol (1995)
The Eye Diseases Prevalence Research Group. Causes and prevalence of visual impairment among adults in the United States
(2004)
Morphology of Aqueous Outflow Pathways in Normal and Glaucomatous Eyes
E Lûtjen-Drecoll (1996)
10.1007/s00018-005-5143-y
Human selenoproteins at a glance
S. Gromer (2005)
10.1039/A707292I
Selenium speciation in human body fluids.
C. Thomson (1998)
Family History and Risk of Primary Open Angle Glaucoma
J. Tielsch (2010)
10.1097/00055735-199604000-00016
Glaucoma risk factors observed in the Baltimore Eye Survey.
A. Sommer (1996)
Glaucoma risk factor assessment
Ophthalmol (1996)
Preventing vision loss from glaucoma: putting data from clinical trials into practice.
D. Schoenleber (2005)
Immunohistochemical localization of peroxidative enzymes in ocular tissue.
L. Atalla (1990)
10.3109/02713688409007413
Purification and characterization of glutathione S-transferases in human retina.
S. Singh (1984)
10.1016/S0022-5347(05)65759-X
SELECT: THE NEXT PROSTATE CANCER PREVENTION TRIAL
E. Klein (2001)
10.1016/S0002-9394(99)00032-X
Antioxidant enzymes in the macular retinal pigment epithelium of eyes with neovascular age-related macular degeneration.
R. Frank (1999)
10.1016/J.OPHTHA.2004.02.017
Predictive factors for glaucomatous visual field progression in the Advanced Glaucoma Intervention Study.
K. Nouri-Mahdavi (2004)
10.1016/S0161-6420(84)34248-8
Trabecular meshwork cellularity in primary open-angle glaucoma and nonglaucomatous normals.
J. Alvarado (1984)
10.1167/IOVS.03-0012
Determinants of intraocular pressure and its association with glaucomatous optic neuropathy in Chinese Singaporeans: the Tanjong Pagar Study.
P. Foster (2003)
10.1007/978-3-642-74421-1
Selenium in Biology and Medicine
A. Wendel (1989)
10.1093/jn/117.12.2002
The two faces of selenium.
J. Oldfield (1987)
10.1016/S0161-6420(96)30449-1
Prevalence of open-angle glaucoma in Australia. The Blue Mountains Eye Study.
P. Mitchell (1996)
The toxicology of selenium and its compounds
W C Cooper (1974)
Intraocular pressure and visual field loss in primary angle closure and primary open angle glaucoma
G Gazzard (2003)
The facts and controversies about selenium.
S. Dodig (2004)
10.1016/S0006-3061(00)80164-7
Selenium in human nutrition: dietary intakes and effects of supplementation.
G. Schrauzer (1978)
10.1001/ARCHOPHT.124.5.633
Effect of moderate intraocular pressure changes on topographic measurements with confocal scanning laser tomography in patients with glaucoma.
M. Nicolela (2006)
10.1016/0006-2952(95)00119-K
Dissociation of the genotoxic and growth inhibitory effects of selenium.
J. Lu (1995)
Selenium in biomedicine
Gruyter de (1989)
10.1016/S0002-9394(14)71681-2
Severity of optic nerve damage in eyes with POAG is correlated with changes in the trabecular meshwork.
J. Gottanka (1997)
10.1167/IOVS.05-0209
Anterior optic nerve capillary blood flow response to diurnal variation of mean ocular perfusion pressure in early untreated primary open-angle glaucoma.
M. Sehi (2005)
10.3109/09286589709057098
Prevalence of glaucoma in Ponza, Italy: a comparison with other studies.
C. Cedrone (1997)
10.1016/S0039-6257(96)80066-X
The extracellular matrix and its modulation in the trabecular meshwork.
B. Yue (1996)
10.1136/bjo.80.5.389
Number of people with glaucoma worldwide.
H. Quigley (1996)
10.1016/S0161-6420(98)92665-3
Prevalence of glaucoma and intraocular pressure distribution in a defined population. The Egna-Neumarkt Study.
L. Bonomi (1998)
10.1159/000082770
Selenium, selenoproteins and vision.
L. Flohe (2005)
10.1038/210949a0
Distribution of Selenium in the Tissues of the Eye
H. H. Taussky (1966)
10.3109/02713688809015149
Immunohistochemical localization of glutathione peroxidase in ocular tissue.
L. Atalla (1988)
10.1136/bjo.50.10.570
Intra-ocular pressure, glaucoma, and glaucoma suspects in a defined population.
F. Hollows (1966)
10.1016/J.AJO.2004.04.058
An evidence-based assessment of risk factors for the progression of ocular hypertension and glaucoma.
D. Friedman (2004)
Prevent Blindness America. Vision problems in the
(2002)
10.1016/S1350-9462(01)00015-5
MMPs in the eye: emerging roles for matrix metalloproteinases in ocular physiology
Jeremy M. Sivak (2002)
10.1136/bjo.65.1.46
The prevalence of glaucoma.
B. Bengtsson (1981)
10.1097/00055735-200404000-00011
Current management of glaucoma
K. Schwartz (2004)
10.1016/J.OPHTHA.2004.02.002
Prevalence and risk indicators of visual impairment and blindness in Latinos: the Los Angeles Latino Eye Study.
R. Varma (2004)
10.1016/J.MRFMMM.2004.02.019
Making sense of sex and supplements: differences in the anticarcinogenic effects of selenium in men and women.
D. J. Waters (2004)
10.1016/J.AJO.2004.04.060
Glaucoma risk factor assessment and prevention: lessons from coronary heart disease.
C. Girkin (2004)
10.1007/BF02778987
Protective role of selenium against hepatitis B virus and primary liver cancer in Qidong
Shu Yu Yu (2007)
10.1016/S0161-6420(84)34241-5
Trabecular meshwork cell culture in glaucoma research: evaluation of biological activity and structural properties of human trabecular cells in vitro.
J. Polansky (1984)
Speciation of selenoaminoacids and organoselenium compounds in selenium-enriched yeast using high-performanc liquid chromatography-inductively coupled plasma mass spectrometry
S Bird (1997)
10.1002/(SICI)1098-2744(199912)26:4<213::AID-MC1>3.0.CO;2-Z
Selenium-induced inhibition of angiogenesis in mammary cancer at chemopreventive levels of intake.
C. Jiang (1999)
10.1093/oxfordjournals.jbchem.a124168
Cloning of the bovine plasma selenium-dependent glutathione peroxidase (GP) cDNA from the ocular ciliary epithelium: expression of the plasma and cellular forms within the mammalian eye.
J. M. Martín-Alonso (1993)
10.1002/BDRC.20065
Matrix metalloproteinases in development and disease.
V. Lemaître (2006)
10.1093/AJCN/85.1.289S
Vitamin and mineral supplements for cancer prevention: issues and evidence.
K. Fairfield (2007)
10.1001/ARCHOPHT.122.4.477
Causes and prevalence of visual impairment among adults in the United States.
N. Congdon (2004)
Does sex matter in glaucoma?[comment
EJ Higginbotham (2004)
10.1016/S0039-6257(99)00050-8
Vascular aspects in the pathophysiology of glaucomatous optic neuropathy.
Hak Sung Chung (1999)
Intraocular pressure and visual field loss in primary angle closure and primary open angle glaucoma
G Gazzard (2003)
Oral contraceptives: their side effects and ophthalmological manifestations.
Chizek Dj (1969)
10.1034/J.1600-0420.2001.079004336.X
Simultaneous management of blood flow and IOP in glaucoma.
A. Harris (2001)
10.1001/jama.1996.03540240035027
Effects of Selenium Supplementation for Cancer Prevention in Patients With Carcinoma of the Skin: A Randomized Controlled Trial
L. C. Clark (1996)
10.1016/J.MEHY.2006.01.058
Cancer chemoprevention: selenium as a prooxidant, not an antioxidant.
E. N. Drake (2006)
10.1016/S0161-6420(03)00101-5
Correlation between intraocular pressure level and optic disc changes in high-tension glaucoma suspects.
M. Tanito (2003)
10.1079/PNS2005467
Selenium in cancer prevention: a review of the evidence and mechanism of action.
M. Rayman (2005)
10.1016/j.preteyeres.2004.08.003
Understanding mechanisms of pressure-induced optic nerve damage
J. Morrison (2005)
Morphology of Aqueous Outflow Pathways in Normal and Glaucomatous Eyes
E Lûtjen-Drecoll (1996)
10.1093/AJCN/79.5.755
Dietary fat consumption and primary open-angle glaucoma.
J. Kang (2004)
10.1097/00061198-199608000-00011
Molecular genetics of glaucoma: current status.
W. L. Alward (1996)
10.1093/ajcn/62.6.1424S
The Linxian trials: mortality rates by vitamin-mineral intervention group.
W. Blot (1995)
10.1016/S0161-6420(98)94031-3
The prevalence of glaucoma in the Melbourne Visual Impairment Project.
M. Wensor (1998)
Selenium supplementation and risk of glaucoma in the NPC trial
A Lillico (2002)
10.1001/ARCHOPHT.122.3.374
Does sex matter in glaucoma?
E. Higginbotham (2004)
10.1093/ajcn/53.3.748
Selenium distribution in blood fractions of New Zealand women taking organic or inorganic selenium.
J. Butler (1991)
10.2165/00002512-200522040-00004
The Economic Burden of Glaucoma and Ocular Hypertension
J. Rouland (2005)
10.1016/S0891-5849(99)00173-2
Tissue-specific functions of individual glutathione peroxidases.
R. Brigelius-Flohé (1999)
10.3109/02713688709025227
Immunohistochemical localization of catalase in ocular tissue.
L. Atalla (1987)
10.1016/J.OPHTHA.2005.03.016
Effects of moderate changes in intraocular pressure on ocular hemodynamics in patients with primary open-angle glaucoma and healthy controls.
G. Weigert (2005)
10.1093/ajcn/53.5.1288
Selenium in diet, blood, and toenails in relation to human health in a seleniferous area.
M. Longnecker (1991)
10.1167/IOVS.04-0987
The effect of age on optic nerve head blood flow.
A. Boehm (2005)
Studies of safe maximal daily dietary Se-intake in a seleniferous area in China. Part II: Relation between Se-intake and the manifestation of clinical signs and certain biochemical alterations in blood and urine.
G. Yang (1989)
Serum selenium and diabetes in U.S. adults
J Bleys (2007)
Natural mechanisms protectin against cancer
M Jakobisiak (2003)
Accuracy and implications of a reported family history of glaucoma: experience from the Glaucoma Inheritance Study in Tasmania.
A. McNaught (2000)
Urinary excretion of luteinizing hormone in women with glaucoma.
Tadeusz Niebrój (1970)
10.1093/oxfordjournals.aje.a112428
The Framingham Eye Study. I. Outline and major prevalence findings.
H. Kahn (1977)
10.1016/J.CDP.2003.11.002
Selenium and selenomethionine levels in prostate cancer patients.
D. Nyman (2004)
10.1001/archopht.1994.01090180121046
The Barbados Eye Study. Prevalence of open angle glaucoma.
M. C. Leske (1994)
10.1016/S0090-4295(00)00970-5
Randomized, controlled chemoprevention trials in populations at very high risk for prostate cancer: Elevated prostate-specific antigen and high-grade prostatic intraepithelial neoplasia.
L. C. Clark (2001)
10.1006/exer.1996.0058
Matrix metalloproteinases and their inhibitors in aqueous humor.
S. Huang (1996)
10.1080/02713680500477347
Glutathione-Related Enzymes and the Eye
E. Ganea (2006)
10.1016/S0161-6420(92)31774-9
Prevalence of glaucoma. The Beaver Dam Eye Study.
B. Klein (1992)
Nutritional Prevention of Cancer: Review of Glaucoma Data. Tucson, AZ
JR Marshall (2002)
10.1093/AJCN/85.1.314S
Clinical trials of vitamin and mineral supplements for cancer prevention.
P. Greenwald (2007)
10.1016/S0009-8981(97)06520-0
Extracellular glutathione peroxidase and ascorbic acid in aqueous humor and serum of patients operated on for cataract.
W. Haung (1997)
10.1016/S0008-4182(05)80012-2
Microvessels of the human optic nerve head: ultrastructural and radioreceptorial changes in eyes with increased IOP.
J. Fehér (2005)
10.1515/9783110861990
Selenium in medicine and biology
J. Neve (1989)
10.1016/S0161-6420(02)01716-5
Changes in optic nerve head blood flow after therapeutic intraocular pressure reduction in glaucoma patients and ocular hypertensives.
A. S. Hafez (2003)
10.1207/S15327914NC401_12
Antiangiogenic Activity of Selenium in Cancer Chemoprevention: Metabolite-Specific Effects
J. Lu (2001)
10.3109/02713689609007621
Antioxidant enzymes of the human retina: effect of age on enzyme activity of macula and periphery.
M. A. De la Paz (1996)
10.1097/00055735-200304000-00003
Ocular Hypertension Treatment Study (OHTS) commentary.
Lee Bl (2003)
Baseline characteristics and the effect of selenium supplementation on cancer incidence in a randomized clinical trial: a summary report of the Nutritional Prevention of Cancer Trial.
A. J. Duffield-Lillico (2002)
Effects of selnium, chromium and antioxidants on growth, eye cataracts, plasma cholesterol and blood glucose in selenium deficient, vitamin E-supplemented rats
PD Whanger (1975)
10.3109/02713688408997189
Glutathione and ocular photobiology.
J. Megaw (1984)
10.1167/IOVS.03-0516
Heritability of risk factors for primary open-angle glaucoma: the Beaver Dam Eye Study.
B. Klein (2004)
10.1002/BDRC.20063
Proteases in eye development and disease.
M. Wride (2006)
10.1016/S0002-9394(03)00143-0
Glaucoma clinical trials and what they mean for our patients.
P. Lichter (2003)
Selenium deficiency lesions in rats fed vitamin E supplemented rations.
L. H. Sprinker (1971)
Selenium in biomedicine
OH Muth (1967)
10.1136/bjo.87.6.720
Intraocular pressure and visual field loss in primary angle closure and primary open angle glaucomas
G. Gazzard (2003)
Speciation of selenoaminoacids and organoselenium compounds in selenium-enriched yeast using high-performanc liquid chromatography-inductively coupled plasma mass spectrometry
S Bird (1997)
Changing views on open-angle glaucoma: definitions and prevalences--The Rotterdam Study.
R. Wolfs (2000)
10.1590/S0100-879X2001000500018
Regulation of antioxidant enzyme activities in male and female rat macrophages by sex steroids.
R. B. Azevedo (2001)
10.1097/01.ijg.0000131757.63542.24
The Aqueous Outflow System as a Mechanical Pump: Evidence from Examination of Tissue and Aqueous Movement in Human and Non-Human Primates
M. Johnstone (2004)
10.1038/sj.eye.6701746
New paradigms in the mechanisms and management of glaucoma
H. Quigley (2005)
Selenium in biology.
D. Frost (1975)
10.1016/J.MRREV.2005.11.001
The role of oxidative stress in glaucoma.
A. Izzotti (2006)
cell homeostatis by selenium
SH (2006)
Selenium, selenoproteins and vision. Developments in Ophthalmology 2005;38:89-102
L. Flohe (2005)
Serum Selenium and Diabetes in U.S. Adults
Joachim Bleys (2007)
10.1097/00055735-199804000-00007
Pathogenetic mechanisms of glaucoma not related to intraocular pressure
G. Douglas (1998)
10.1093/JNCI/DJH310
Selenium and colorectal adenoma: results of a pooled analysis.
E. Jacobs (2004)
10.1016/J.EXER.2005.08.024
Alterations in human trabecular meshwork cell homeostasis by selenium.
Shannon M Conley (2006)
10.1167/IOVS.05-0289
Pathophysiologic changes in the optic nerves of eyes with primary open angle and pseudoexfoliation glaucoma.
J. Gottanka (2005)
10.1093/oxfordjournals.aje.a113626
The epidemiology of open-angle glaucoma: a review.
M. C. Leske (1983)
levels in prostate cancer patients
W Alward (2004)
Nutritional prevention of cancer: review of glaucoma data
JR Marshall (2002)
10.1016/S0092-8674(00)80108-7
Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis
D. Hanahan (1996)
Nutritional Prevention of Cancer: Review of Glaucoma Data. Tucson, AZ
JR Marshall (2002)
10.1097/00061198-199704000-00009
Severity of Optic Nerve Damage in Eyes with POAG Is Correlated with Changes in the Trabecular Meshwork
Johannes Gottanka (1997)
Selenium, retinol, retinolbinding protein, and uric acid. Associations with cancer mortality in a populationbased prospective case-control study
MH Criqui (1991)
Selenium, selenoproteins and vision. Developments in Ophthalmology 2005;38:89-102
L. Flohe (2005)
Effects of selnium, chromium and antioxidants on growth, eye cataracts, plasma cholesterol and blood glucose in selenium deficient, vitamin E-supplemented rats
PD Whanger (1975)
10.1093/JN/128.11.1845
Lessons from basic research in selenium and cancer prevention.
C. Ip (1998)
10.1016/J.IMLET.2003.08.005
Natural mechanisms protecting against cancer.
M. Jakóbisiak (2003)
10.1042/BJ20050149
More roles for selenoprotein P: local selenium storage and recycling protein in the brain.
D. Richardson (2005)
10.1001/ARCHOPHT.120.12.1726
Family score as an indicator of genetic risk of primary open-angle glaucoma.
C. A. Hulsman (2002)
10.1111/J.1444-0938.2002.TB02384.X
The mechanism of aqueous humour formation.
C. To (2002)
10.1002/1098-2744(200012)29:4<236::AID-MC1006>3.0.CO;2-E
Monomethyl selenium--specific inhibition of MMP-2 and VEGF expression: implications for angiogenic switch regulation.
C. Jiang (2000)
10.1016/0891-5849(94)90007-8
On the nature of selenium toxicity and carcinostatic activity.
J. Spallholz (1994)
10.1093/ajcn/37.5.872
Endemic selenium intoxication of humans in China.
G. Yang (1983)
Natural mechanisms protectin against cancer
M Jakobisiak (2003)
10.1016/S0140-6736(04)16257-0
Primary open-angle glaucoma
R. Weinreb (2004)
10.1016/S0002-9394(99)00468-7
Estrogen-replacement therapy: effects on retrobulbar hemodynamics.
M. Harris-Yitzhak (2000)
10.1152/ajpendo.1991.261.1.E26
Response of rat selenoprotein P to selenium administration and fate of its selenium.
R. Burk (1991)
10.1023/A:1011277600059
Molecular epidemiologic studies within the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
A. Hoque (2004)
10.1159/000267087
Selenium concentration in ocular tissues and fluids.
M. C. Mcgahan (1991)
10.1046/j.1464-410X.2003.04167.x
Selenium supplementation, baseline plasma selenium status and incidence of prostate cancer: an analysis of the complete treatment period of the Nutritional Prevention of Cancer Trial
A. J. Duffield-Lillico (2003)
10.1001/archopht.1994.01090130079022
Family history and risk of primary open angle glaucoma. The Baltimore Eye Survey.
J. Tielsch (1994)
10.1016/0039-6257(90)90122-C
Intraocular pressure: new perspectives.
Y. Shiose (1990)
10.1016/S0065-230X(08)60862-3
How tumors become angiogenic.
N. Bouck (1996)
10.1146/annurev.nu.07.070187.001303
A global view of human selenium nutrition.
O. Levander (1987)
Selenium in biology and medicine
G. Combs (1987)
10.1016/S0161-6420(94)31090-6
The prevalence of primary open-angle glaucoma in a population-based study in The Netherlands. The Rotterdam Study.
I. Dielemans (1994)
10.1074/JBC.M101143200
Inhibitory Effect of Selenite on Invasion of HT1080 Tumor Cells*
S. Yoon (2001)
Oxidative damage and age-related macular degeneration.
B. Winkler (1999)
10.1001/archopht.1991.01080090111033
Antioxidant enzymes in the aging human retinal pigment epithelium.
M. Liles (1991)
Effect of sex hormones on intraocular pressure.
P. Avasthi (1967)
Selenium supplementation and lung cancer incidence: an update of the nutritional prevention of cancer trial.
M. Reid (2002)
10.1093/AJCN/85.1.269S
Multivitamin and multimineral dietary supplements: definitions, characterization, bioavailability, and drug interactions.
E. Yetley (2007)
10.1167/IOVS.05-0541
Factors influencing optic nerve head biomechanics.
I. Sigal (2005)
10.1097/00042192-199906010-00005
Postmenopausal estrogen therapy and selected (less-often-considered) disease outcomes.
E. Barrett-connor (1999)
10.1016/j.preteyeres.2004.06.001
The optic nerve head as a biomechanical structure: a new paradigm for understanding the role of IOP-related stress and strain in the pathophysiology of glaucomatous optic nerve head damage
C. Burgoyne (2005)
10.1076/ceyr.28.2.135.26232
Alterations in lens protein tyrosine phosphorylation and phosphatidylinositol 3-kinase signaling during selenite cataract formation
G. Chandrasekher (2004)
10.1016/j.preteyeres.2004.10.003
Changes in aqueous humor dynamics with age and glaucoma
B’Ann T. Gabelt (2005)
Oral contraceptives: their side effects and ophthalmological manifestations.
D. J. Chizek (1969)
10.1016/S0002-9394(03)00632-9
Evaluation of optic nerve head and peripapillary retinal blood flow in glaucoma patients, ocular hypertensives, and normal subjects.
A. S. Hafez (2003)



This paper is referenced by
10.2478/jomb-2013-0024
SELENIUM AND SELENOPROTEIN P1 LEVELS ARE RELATED TO PRIMARY OPEN-ANGLE GLAUCOMA / NIVOI SELENA I SELENOPROTEINA P1 POVEZANI SU SA PRIMARNIM GLAUKOMOM OTVORENOG UGLA
Mohammad Najafi (2013)
10.1016/j.jtemb.2017.10.003
Levels of aqueous humor trace elements in patients with open-angle glaucoma.
Bettina Hohberger (2018)
10.1007/s12011-013-9644-5
Evaluation of Essential and Toxic Trace Elements in Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma
O. M. Ceylan (2013)
10.1080/10590501.2013.844757
Friend or Foe? The Current Epidemiologic Evidence on Selenium and Human Cancer Risk
Marco Vinceti (2013)
10.1097/MOL.0b013e3283433a5b
Current World Literature
(2011)
Development of confocal X-ray fluorescence techniques for biological and archaeological applications
Sanjukta Choudhury (2016)
10.1021/es503848s
Selenium preferentially accumulates in the eye lens following embryonic exposure: a confocal X-ray fluorescence imaging study.
Sanjukta Choudhury (2015)
10.1111/ceo.12732
Biochemical analysis of the living human vitreous
Jan Kokavec (2016)
10.1016/j.jtemb.2018.06.010
Aqueous humor selenium level and open-angle glaucoma.
Anselm Gerhard Maria Jünemann (2018)
10.1002/14651858.CD005195.pub3
Selenium for preventing cancer.
M. Vinceti (2014)
10.1002/14651858.CD005195.PUB4
سلنیوم برای پیشگیری از سرطان
M. Vinceti (2018)
10.1002/9781118834015.CH30
Selenium and its compounds
Anna M. Fan (2015)
10.1016/j.jtemb.2019.02.006
Levels of serum trace elements in patients with primary open-angle glaucoma.
Alexander Fick (2019)
Selenium and ocular health in New Zealand.
L. H. N. Sheck (2010)
10.1016/j.ajo.2010.08.032
Selenium and pseudoexfoliation syndrome.
Ayça Dilara Yilmaz (2011)
10.1136/bjo.2008.141218
Should we be considering selenium in glaucoma?
A. King (2009)
10.17116/oftalma201813424-11
[Influence of chemical compositions of anterior chamber aqueous humour and blood serum on the secretion of intraocular fluid].
A. Ermolaev (2018)
10.1111/aos.13662
The relation between dietary intake and glaucoma: a systematic review
W. Ramdas (2018)
10.1016/j.scitotenv.2012.11.025
The need for a reassessment of the safe upper limit of selenium in drinking water.
M. Vinceti (2013)
10.1002/14651858.CD005195.pub2
Selenium for preventing cancer.
G. Dennert (2011)
10.1007/s40572-018-0213-0
Environmental Selenium and Human Health: an Update
M. Vinceti (2018)
10.1111/j.1755-3768.2011.02356.x
Nutritional, lifestyle and environmental factors in ocular hypertension and primary open‐angle glaucoma: an exploratory case–control study
J. Renard (2013)
10.1007/s15013-013-0017-0
Gynäkologische Aspekte
C. Keck (2013)
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