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Molecular, Functional, And Pathological Aspects Of The Mitochondrial ADP/ATP Carrier

C. Dahout-Gonzalez, H. Nury, V. Trézéguet, G. J.-M. Lauquin, E. Pebay-Peyroula, G. Brandolin

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In providing the cell with ATP generated by oxidative phosphorylation, the mitochondrial ADP/ATP carrier plays a central role in aerobic eukaryotic cells. Combining biochemical, genetic, and structural approaches contributes to understanding the molecular mechanism of this essential transport system, the dysfunction of which is implicated in neuromuscular diseases.