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Aquaporins: Phylogeny, Structure, And Physiology Of Water Channels

J. Bernard Heymann, Andreas Engel

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How water permeates cellular membranes and what this means for cell functioning and several diseases are now emerging from the study of the aquaporins (AQPs), the water channel family. A combination of sequence analysis, three-dimensional structure determination, and physiology of the AQP family proteins provides a glimpse into the workings of water channels.