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Successful Intravenous Rt-PA Thrombolysis For A Childhood Cardioembolic Stroke With Emery-Dreifuss Muscular Dystrophy

K. Tanaka, T. Uehara, K. Sato, Tatsuo Amano, K. Minematsu, K. Toyoda
Published 2011 · Medicine

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Case Report A right-handed 12-year-old boy had suffered from pathologically proven EDMD for 7 years and required a wheelchair in daily life due to limb weakness. He had been given warfarin for one year because of chronic atrial fibrillation and suddenly developed leftsided motor weakness and was admitted to our hospital. On admission, he was alert and had a conjugate gaze deviation to the right, dysarthria, and complete left hemiparesis including the face. His National Institute of Health Stroke Scale (NIHSS) score was 15. International Normalized Ratio (INR) was 1.49. Head CT showed indistinctness of the right lenticular nuclei and a right hyIntroduction Patients and carriers of Emery-Dreifuss muscular dystrophy (EDMD), a known inherited muscular disorder [1] , are at high risk of sudden death due to arrhythmias, heart failure, and embolism Published online: December 13, 2011
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