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Synthesis And Characterization Of PLGA Nanoparticles

C. Astete, C. Sabliov
Published 2006 · Materials Science, Medicine

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Poly(lactide-co-glycolide) (PLGA) nanoparticles of different physical characteristics (size, size distribution, morphology, zeta potential) can be synthesized by controlling the parameters specific to the synthesis method employed. The aim of this review is to clearly, quantitatively and comprehensively describe the top–down synthesis techniques available for PLGA nanoparticle formation, as well as the techniques commonly used for nanoparticle characterization. Many examples are discussed in detail to provide the reader with an extensive knowledge base on the important parameters specific to the synthesis method described and ways in which these parameters can be manipulated to control the nanoparticle physical characteristics.
This paper references
10.1023/B:PHAM.0000008051.94834.10
Surfactant-Free, Biodegradable Nanoparticles for Aerosol Therapy Based on the Branched Polyesters, DEAPA-PVAL-g-PLGA
L. A. Dailey (2004)
10.1016/S0928-0987(01)00203-2
Compromised integrity of excised porcine intestinal epithelium obtained from the abattoir affects the outcome of in vitro particle uptake studies.
Peter Pietzonka (2002)
10.1016/S0168-3659(01)00535-1
Double emulsions: how does release occur?
K. Pays (2002)
10.1208/pt040101
Synergistic effect of PEG-400 and cyclodextrin to enhance solubility of progesterone
I. Nandi (2008)
10.1016/0168-3659(93)90097-O
Preparations of biodegradable nanospheres of water-soluble and insoluble drugs with D, L-lactide/glycolide copolymer by a novel spontaneous emulsification solvent diffusion method, and the drug release behavior.
Toshiyuki (1993)
Preparation and characterization of sterile and freeze-dried sub-200 nanoparticles
Y. Konan (2002)
Synthesis and characterization of PLGA nanoparticles
K. Landfester (2003)
10.1023/A:1007503123620
The in Vitro Cell Association of Invasin Coated Polylactide-Co-glycolide Nanoparticles
G. Dawson (2004)
10.1021/JP027339N
Phase Transition of the PLGA-g-PEG Copolymer Aqueous Solutions
B. Jeong (2003)
10.1016/J.BIOMATERIALS.2004.07.050
Effects of particle size and surface coating on cellular uptake of polymeric nanoparticles for oral delivery of anticancer drugs.
K. Y. Win (2005)
10.1016/J.JCONREL.2004.09.008
In vitro degradation of nanoparticles prepared from polymers based on DL-lactide, glycolide and poly(ethylene oxide).
Miechel L T Zweers (2004)
10.1002/APP.1326
Preparation of poly(DL‐lactide‐co‐glycolide) nanoparticles without surfactant
Y. Jeong (2001)
10.1023/A:1021373731787
Intracellular drug delivery using poly(d,l-lactide-co-glycolide) nano- particles derivatized with a peptide from a transcriptional activator protein of HIV-1
Y. Nam (2004)
10.1016/S0168-3659(02)00320-6
A novel controlled release formulation for the anticancer drug paclitaxel (Taxol): PLGA nanoparticles containing vitamin E TPGS.
L. Mu (2003)
10.1021/BM049577P
PLGA:poloxamer and PLGA:poloxamine blend nanoparticles: new carriers for gene delivery.
N. Csaba (2005)
10.1080/01932690208984204
A Comparison of Membrane Emulsification Obtained Using SPG (Shirasu Porous Glass) and PTFE [Poly(Tetrafluoroethylene)] Membranes
N. Yamazaki (2002)
Microencapsulation : methods and industrial applications
S. Benita (1996)
10.1208/pt040471
Optimization of polylactic-co-glycolic acid nanoparticles containing itraconazole using 23 factorial design
Mukdavan Prakobvaitayakit (2008)
10.1166/JNN.2004.120
Cationic silica nanoparticles as gene carriers: synthesis, characterization and transfection efficiency in vitro and in vivo.
M. Ravi Kumar (2004)
10.1021/MP049970+
Nanoparticle-mediated wild-type p53 gene delivery results in sustained antiproliferative activity in breast cancer cells.
S. Prabha (2004)
10.1023/A:1015393710253
Transfer of Lipophilic Markers from PLGA and Polystyrene Nanoparticles to Caco-2 Monolayers Mimics Particle Uptake
Peter Pietzonka (2004)
10.1016/S0021-9797(03)00591-5
Physicochemical evaluation of PLA nanoparticles stabilized by water-soluble MPEO-PLA block copolymers.
D. Chognot (2003)
10.1016/S0378-5173(03)00295-3
Fluorescence and electron microscopy probes for cellular and tissue uptake of poly(D,L-lactide-co-glycolide) nanoparticles.
J. Panyam (2003)
10.1163/15685620360511100
Synthesis and characterization of poly(L-lysine)-g-poly(D,L-lactic-co-glycolic acid) biodegradable micelles
J. Jeong (2003)
10.1016/S0927-7765(99)00156-3
'Stealth' corona-core nanoparticles surface modified by polyethylene glycol (PEG): influences of the corona (PEG chain length and surface density) and of the core composition on phagocytic uptake and plasma protein adsorption.
Gref (2000)
10.1002/PI.1697
Factors affecting the degradation and drug-release mechanism of poly(lactic acid) and poly[(lactic acid)-co-(glycolic acid)]
F. Alexis (2005)
10.1016/S0939-6411(97)00056-8
Development and characterization of protein-loaded poly(lactide-co-glycolide) nanospheres
M. D. Blanco (1997)
10.1016/S0376-7388(99)00334-8
Membrane emulsification — a literature review
S. Joscelyne (2000)
10.1007/S11998-004-0026-Y
Preparation of polymerizable miniemulsions by ultrasonication
K. Landfester (2004)
10.1016/J.VACCINE.2003.12.032
Characterization of poly(D,L-lactic-co-glycolic acid) based nanoparticulate system for enhanced delivery of antigens to dendritic cells.
Praveen Elamanchili (2004)
10.1016/S0927-7765(99)00066-1
COLLOIDAL STABILITY AND DRUG INCORPORATION ASPECTS OF MICELLAR-LIKE PLA-PEG NANOPARTICLES
T. Riley (1999)
10.1023/B:PHAM.0000045247.09724.26
Binding and Uptake of Wheat Germ Agglutinin-Grafted PLGA-Nanospheres by Caco-2 Monolayers
A. Weissenboeck (2004)
10.1016/S0939-6411(97)00121-5
Properties of a peptide containing DL-lactide/glycolide copolymer nanospheres prepared by novel emulsion solvent diffusion methods.
Y. Kawashima (1998)
10.1080/107175401316906892
Preparation and In Vitro Evaluation of Heparin-Loaded Polymeric Nanoparticles
Y. Jiao (2001)
10.1021/LA9700580
Shear Rupturing of Droplets in Complex Fluids
T. Mason (1997)
10.1201/9780203904671.CH28
Polymeric Micro- and Nanoparticles as Drug Carriers
G. Barratt (2001)
10.1016/J.EJPB.2004.03.035
The influence of the use of viscosifying agents as dispersion media on the drug release properties from PLGA nanoparticles.
K. Dillen (2004)
10.1023/A:1022219003551
Dynamics of Endocytosis and Exocytosis of Poly(D,L-Lactide-co-Glycolide) Nanoparticles in Vascular Smooth Muscle Cells
J. Panyam (2004)
Encyclopedia of Controlled Drug Delivery
E. Mathiowitz (1999)
10.1016/S0142-9612(02)00641-5
New micelle-like polymer aggregates made from PEI-PLGA diblock copolymers: micellar characteristics and cellular uptake.
Y. Nam (2003)
10.1211/0022357021701
Nanoparticle formulation enhances the delivery and activity of a vascular endothelial growth factor antisense oligonucleotide in human retinal pigment epithelial cells
Jithan V. Aukunuru (2003)
10.1016/S0169-409X(97)00048-3
Biodegradation and biocompatibility of PLA and PLGA microspheres
J. Anderson (1997)
10.1023/A:1024418524688
Polyester-Poly(Ethylene Glycol) Nanoparticles Loaded with the Pure Antiestrogen RU 58668: Physicochemical and Opsonization Properties
T. Ameller (2004)
Handbook of nanostructured materials and nanotechnology
H. Nalwa (2000)
10.1016/J.IJPHARM.2004.03.032
Indocyanine green-loaded biodegradable nanoparticles: preparation, physicochemical characterization and in vitro release.
V. Saxena (2004)
10.1016/S0378-5173(02)00076-5
Investigation of polymeric nanoparticles as carriers of enalaprilat for oral administration.
P. Ahlin (2002)
10.1016/S0169-409X(00)00099-5
Particle control of emulsion by membrane emulsification and its applications.
T. Nakashima (2000)
10.3109/03639049209069315
Preparation of Poly(D,L-Lactide/Glycolide) Nanoparticles of Controlled Particle Size Distribution: Application of Experimental Designs
M. Julienne (1992)
10.1023/A:1015123024113
Prolonged Anti-Inflammatory Action of DL-Lactide/Glycolide Copolymer Nanospheres Containing Betamethasone Sodium Phosphate for an Intra-Articular Delivery System in Antigen-Induced Arthritic Rabbit
E. Horisawa (2004)
10.2174/0929867043455909
Nanoparticles of biodegradable polymers for clinical administration of paclitaxel.
S. Feng (2004)
10.1016/B978-012513760-7/50063-0
Biopolymer and polymer nanoparticles and their biomedical applications
E. Nakache (2000)
10.1016/S0168-3659(96)01484-8
Formulation and characterization of biodegradable nanoparticles for intravascular local drug delivery
Cunxian Song (1997)
10.1211/0022357044210
Oral delivery of spray dried PLGA/amifostine nanoparticles
S. Pamujula (2004)
10.1023/B:PHAM.0000029279.50733.55
Design of Amine-Modified Graft Polyesters for Effective Gene Delivery Using DNA-Loaded Nanoparticles
C. Oster (2004)
10.1023/A:1013674200141
Poly(vinyl alcohol) hydrogels as hydrophilic matrices for the release of lipophilic drugs loaded in PLGA nanoparticles
Maria Grazia Cascone (2002)
10.1016/S0264-410X(02)00435-8
Size dependent immune response after subcutaneous, oral and intranasal administration of BSA loaded nanospheres.
I. Gutierro (2002)
10.1016/J.IJPHARM.2004.05.016
Nano-emulsion formulation using spontaneous emulsification: solvent, oil and surfactant optimisation.
K. Bouchemal (2004)
10.1016/J.EJPS.2003.11.002
Pure antiestrogen RU 58668-loaded nanospheres: morphology, cell activity and toxicity studies.
T. Ameller (2004)
10.1016/J.EJPS.2004.04.003
Cystatin incorporated in poly(lactide-co-glycolide) nanoparticles: development and fundamental studies on preservation of its activity.
Mateja Cegnar (2004)
10.1016/S0168-3659(02)00296-1
Stimulation of spleen cells in vitro by nanospheric particles containing antigen.
J. Eyles (2003)
10.1016/S0928-0987(03)00019-8
Biodegradable micro- and nanoparticles as long-term delivery vehicles for interferon-alpha.
A. Sánchez (2003)
10.1016/S0378-5173(02)00058-3
Biocompatible stabilizers in the preparation of PLGA nanoparticles: a factorial design study.
J. Vandervoort (2002)
10.1023/A:1012117531448
Preparation of Biodegradable, Surface Engineered PLGA Nanospheres with Enhanced Lymphatic Drainage and Lymph Node Uptake
A. E. Hawley (2004)
10.1016/S0168-3659(02)00494-7
Sustained release of human growth hormone from microcapsules prepared by a solvent evaporation technique.
Shigeyuki Takada (2003)
10.1002/JPS.20094
Solid-state solubility influences encapsulation and release of hydrophobic drugs from PLGA/PLA nanoparticles.
J. Panyam (2004)
10.1016/S0168-3659(98)00116-3
PLGA nanoparticles prepared by nanoprecipitation: drug loading and release studies of a water soluble drug.
T. Govender (1999)
10.3109/03639049809108571
Preparation techniques and mechanisms of formation of biodegradable nanoparticles from preformed polymers.
D. Quintanar-Guerrero (1998)
10.1023/A:1018931820564
Surface Modification of Poly(lactide-co-glycolide) Nanospheres by Biodegradable Poly(lactide)-Poly(ethylene glycol) Copolymers
S. Stolnik (2004)
10.3797/SCIPHARM.AUT-01-18
METOPROLOL EFFECT ON FATTY ACIDS COMPOSITION OF CELL MEMBRANE PHOSPHOLIPIDS
G. Swierczek-Zieba (2001)
10.1016/J.JCIS.2003.08.067
Preparation and characterization of biodegradable poly(l-lactide)/poly(ethylene glycol) microcapsules containing erythromycin by emulsion solvent evaporation technique.
S. Park (2004)
Drug-loaded nanoparticles : preparation methods and drug targeting issues
E. Allémann (1993)
Encyclopedia of Control Drug Delivery, E
F. De Jaeghere (1999)
Surfactants and Polymers in Aqueous Solution, 2nd ed.
K. Holmberg (2003)
10.1007/S11771-003-0009-7
Preparation of PLA and PLGA nanoparticles by binary organic solvent diffusion method
Xinyu Jiang (2003)
10.1111/j.1365-2222.2004.01884.x
Allergen‐loaded biodegradable poly(d,l‐lactic‐co‐glycolic) acid nanoparticles down‐regulate an ongoing Th2 response in the BALB/c mouse model
I. Schoell (2004)
10.1016/S0927-7757(02)00167-X
Capillary mechanisms in membrane emulsification: oil-in-water emulsions stabilized by Tween 20 and milk proteins
N. Christov (2002)
NANOPARTICLES AS DRUG DELIVERY SYSTEMS
S. R. Hiremath (1999)
10.1016/S0378-5173(00)00537-8
Effect of solvent on the preparation of surfactant-free poly(DL-lactide-co-glycolide) nanoparticles and norfloxacin release characteristics.
H. Jeon (2000)
10.1096/fj.02-0088com
Rapid endo‐lysosomal escape of poly(DL‐lactide‐coglycolide) nanoparticles: implications for drug and gene delivery
J. Panyam (2002)
10.1615/CRITREVTHERDRUGCARRIERSYST.V21.I5.20
PLGA nanoparticles in drug delivery: the state of the art.
I. Bala (2004)
10.1080/0265204021000022716
Viscosity of polymer solution phase and other factors controlling the dissolution of theophylline microspheres prepared by the emulsion solvent evaporation method.
W. Obeidat (2003)
10.1021/LA0100439
Size Selection in Viscoelastic Emulsions under Shear
X. Z. and (2001)
10.1023/B:PHAM.0000016250.56402.99
Critical Determinants in PLGA/PLA Nanoparticle-Mediated Gene Expression
S. Prabha (2004)
10.1080/10717540490467384
Poly (Lactide-co-Glycolide) Nanoparticles Containing Coumarin-6 for Suppository Delivery: In Vitro Release Profile and In Vivo Tissue Distribution
J. G. Eley (2004)
10.2174/1567201043334605
Pegylated poly(lactide) and poly(lactide-co-glycolide) nanoparticles: preparation, properties and possible applications in drug delivery.
K. Avgoustakis (2004)
10.1016/S0939-6411(02)00128-5
Preparation and characterization of sterile sub-200 nm meso-tetra(4-hydroxylphenyl)porphyrin-loaded nanoparticles for photodynamic therapy.
Y. Konan (2003)
10.1016/j.ejpb.2004.03.008
PLGA–PEI nanoparticles for gene delivery to pulmonary epithelium
M. Bivas-Benita (2004)
10.1080/10611860410001670026
Biodegradable Nanoparticle Mediated Antigen Delivery to Human Cord Blood Derived Dendritic Cells for Induction of Primary T Cell Responses
Manish Diwan (2003)
Emulsion Science, p
J. Bibette (2002)
10.1201/9781420027990
Microencapsulation : Methods and Industrial Applications, Second Edition
S. Benita (2005)
10.1016/S0169-409X(02)00044-3
Nanoparticles in cancer therapy and diagnosis.
I. Brigger (2002)
10.1016/S0927-7757(01)01042-1
Thermodynamic parameters on poly(d,l-lactide-co-glycolide) particle size in emulsification–diffusion process
S. Choi (2002)
10.1016/S0168-3659(02)00211-0
Lipophilic drug loaded nanospheres prepared by nanoprecipitation: effect of formulation variables on size, drug recovery and release kinetics.
M. Chorny (2002)
10.1016/J.IJPHARM.2004.01.033
Factorial design, physicochemical characterisation and activity of ciprofloxacin-PLGA nanoparticles.
K. Dillen (2004)
10.1016/J.YEXCR.2004.07.021
Poly(lactide-co-glycolide) nanoparticles as a carrier system for delivering cysteine protease inhibitor cystatin into tumor cells.
Mateja Cegnar (2004)
10.1002/0470856424
Surfactants and Polymers in Aqueous Solution
B. Jönsson (2002)
10.1163/156855200750172187
Evaluation of Poly(DL-lactide-co-glycolide)Nanoparticles as Matrix Material for Direct Compression.
Murakami (2000)
10.1080/02652040400000520
Hydrophilized poly(lactide-co-glycolide) nanospheres with poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) triblock copolymer
B. Kim (2004)
10.1016/S0927-7757(00)00825-6
Preparation of PLGA nanoparticles containing estrogen by emulsification–diffusion method
Hye young Kwon (2001)
10.1016/J.BIOMATERIALS.2003.08.069
Preparation and characterization of cationic PLGA nanospheres as DNA carriers.
M. Ravi Kumar (2004)
10.1016/S0169-409X(02)00228-4
Biodegradable nanoparticles for drug and gene delivery to cells and tissue.
J. Panyam (2003)
10.1163/1568562041753098
Design and characterisation of new nanoparticulate polymer blends for drug delivery
N. Csaba (2004)
10.1016/S0378-5173(01)00944-9
Preparation and characterization of sterile and freeze-dried sub-200 nm nanoparticles.
Y. Konan (2002)
10.1166/JNN.2004.130
Cationic poly(lactide-co-glycolide) nanoparticles as efficient in vivo gene transfection agents.
M. Kumar (2004)
10.1248/CPB.52.1273
Influence of the homogenisation procedure on the physicochemical properties of PLGA nanoparticles.
J. Vandervoort (2004)
10.1021/LA971271Z
Some Stability Criteria for Double Emulsions
M.-F. Ficheux (1998)
10.1016/S0168-3659(02)00127-X
Residual polyvinyl alcohol associated with poly (D,L-lactide-co-glycolide) nanoparticles affects their physical properties and cellular uptake.
S. Sahoo (2002)
10.1016/J.COLSURFA.2004.12.019
Magnetic enhancement of iron oxide nanoparticles encapsulated with poly(d,l-latide-co-glycolide)
S. Lee (2005)
Long-circulating and target-specific nanoparticles: theory to practice.
S. Moghimi (2001)
10.1103/PHYSREVLETT.77.3481
Emulsification in Viscoelastic Media.
Mason (1996)
10.1007/S003960050130
A mechanistic study of the formation of polymer nanoparticles by the emulsification-diffusion technique
D. Quintanar-Guerrero (1997)
10.1002/JPS.2600830527
In vitro drug release behavior of D,L-lactide/glycolide copolymer (PLGA) nanospheres with nafarelin acetate prepared by a novel spontaneous emulsification solvent diffusion method.
T. Niwa (1994)
10.1163/15685620360511155
Molecular weight distribution changes during degradation and release of PLGA nanoparticles containing epirubicin HCl
D. Birnbaum (2003)
10.1007/978-94-011-4641-8_33
Micro and Nanoparticles as Drug Carriers
S. Leucuţa (1999)
10.1016/S0378-5173(00)00574-3
Effects of the rate of solvent evaporation on the characteristics of drug loaded PLLA and PDLLA microspheres.
T. Chung (2001)
10.1016/S0378-5173(01)00676-7
Effect of dose on the biodistribution and pharmacokinetics of PLGA and PLGA-mPEG nanoparticles.
Z. Panagi (2001)
10.1016/S0928-0987(03)00017-4
Enhanced photodynamic activity of meso-tetra(4-hydroxyphenyl)porphyrin by incorporation into sub-200 nm nanoparticles.
Y. Konan (2003)
10.1021/LA010735X
Coalescence in Surfactant-Stabilized Double Emulsions
K. Pays (2001)
10.1007/3-540-36412-9_4
Miniemulsions for nanoparticle synthesis
K. Landfester (2003)
10.5012/BKCS.2002.23.11.1579
Testosterone-encapsulated Surfactant-free Nanoparticles of Poly(DL-lactide-co-glycolide): Preparation and Release Behavior
Y. Jeong (2002)
10.1016/S0168-3659(02)00131-1
Poly(L-lysine)-g-poly(D,L-lactic-co-glycolic acid) micelles for low cytotoxic biodegradable gene delivery carriers.
J. Jeong (2002)
10.1002/APP.12297
Surfactant‐free nanoparticles of poly(DL‐lactide‐co‐glycolide) prepared with poly(L‐lactide)/ poly(ethylene glycol)
Y. Jeong (2003)
10.1080/02652040210140706
Effects of solvent evaporation rate on the properties of protein-loaded PLLA and PDLLA microspheres fabricated by emulsion-solvent evaporation process
T. Chung (2002)
10.1007/3-540-36412-9_8
Preparation of Monodisperse Particles and Emulsions by Controlled Shear
V. Schmitt (2003)
10.3109/02652049009021845
Encapsulation of water-soluble drugs by a modified solvent evaporation method. I. Effect of process and formulation variables on drug entrapment.
R. Alex (1990)
10.1016/S1359-0286(02)00117-1
Biodegradable nanoparticles for drug delivery and targeting
M. Hans (2002)
10.1016/S1359-0294(03)00019-0
Synthesis of nanomaterials in microemulsions: formation mechanisms and growth control ☆
M. A. López-Quintela (2003)



This paper is referenced by
10.1117/1.JBO.17.11.116025
Indocyanine-green-loaded microballoons for biliary imaging in cholecystectomy
K. Mitra (2012)
10.1007/s00266-010-9610-y
Microencapsulated Myoblasts Transduced by the Vascular Endothelial Growth Factor (VEGF) Gene for the Ischemic Skin Flap
W. Chen (2010)
10.1021/acs.molpharmaceut.7b00862
Characteristics of Artemether-Loaded Poly(lactic-co-glycolic) Acid Microparticles Fabricated by Coaxial Electrospray: Validation of Enhanced Encapsulation Efficiency and Bioavailability.
F. Mangrio (2017)
10.22677/thesis.2321563
Fabrication and characterization of 2 dimensional biodegradable microrobot with 5 Fluorouracil for targeted drug delivery
S. H. Jeon (2017)
10.1007/978-3-319-95990-0
Functional Biopolymers
M. A. J. Mazumder (2019)
10.1111/1750-3841.12874
Physical Stability of Octenyl Succinate-Modified Polysaccharides and Whey Proteins for Potential Use as Bioactive Carriers in Food Systems.
A. F. Puerta-Gomez (2015)
10.1021/acsami.6b01277
Core-Shell Chitosan Microcapsules for Programmed Sequential Drug Release.
Xiu-lan Yang (2016)
10.1007/5584_2018_302
Synthesis and Characterization of PLGA-PEG Thymoquinone Nanoparticles and Its Cytotoxicity Effects in Tamoxifen-Resistant Breast Cancer Cells.
Rozaina Ahmad (2018)
10.1039/C1SM05079F
Examination and optimization of the self-assembly of biocompatible, polymeric nanoparticles by high-throughput nanoprecipitation
Igor Perevyazko (2011)
10.1124/jpet.118.254953
Poly(d,l-lactide-co-glycolide) Nanoparticles as Delivery Platforms for TLR7/8 Agonist-Based Cancer Vaccine
Hyunjoon Kim (2019)
10.1134/S1061933X15050105
Tuning the size of gelatin nanoparticles produced by nanoprecipitation
S. A. Khan (2015)
10.22317/jcms.12201704
Effect of formulation parameters on the size of PLGA nanoparticles encapsulating bovine serum albumin: a response surface methodology
Tajudeen Adebileje (2017)
Curcumin containing chitosan-pectinate nanoparticulate drug delivery system for colon cancer treatment
Enas Alkhader (2018)
Tools for decoding the structure-function relationships of biopolymers in nanotechnology and glycobiology
Venkataramanan Soundararajan (2010)
Thursday, November 8, 2007
Tobias Josef Brunner (2007)
10.1002/adhm.201200268
Micro and nanoparticle-based delivery systems for vaccine immunotherapy: an immunological and materials perspective.
Jardin A Leleux (2013)
10.1016/J.JFOODENG.2017.02.020
Sustainable extraction and encapsulation of pink pepper oil
K. Andrade (2017)
Dual Drug-Loaded Electrospun Nanofibres for the Treatment of Corneal Diseases
E. Tawfik (2019)
10.3109/10717544.2015.1136713
Improved oral efficacy of epirubicin through polymeric nanoparticles: pharmacodynamic and toxicological investigations
M. Tariq (2016)
10.1111/jre.12695
Titanium coated with poly(lactic-co-glycolic) acid incorporating simvastatin: Biofunctionalization of dental prosthetic abutments.
G. J. S. Littuma (2019)
10.1016/j.supflu.2020.104822
Encapsulation of pink pepper extract by SEDS technique: Phase behavior data and process parameters
K. Andrade (2020)
10.37358/mp.19.4.5277
Studying the Effect of PMG on the Hydrodynamic Characteristics and Stability of PLGA-Vegetable Oil Hybrid Nanoparticles Obtained by Emulsion Solvent Evaporation Method
Jana Ghitman (2019)
10.1016/J.NHTM.2014.11.058
Revolutionary impact of nanovaccines on immunotherapy
M. Shahbazi (2014)
10.1016/j.jconrel.2015.05.004
Engineering of a novel adjuvant based on lipid-polymer hybrid nanoparticles: A quality-by-design approach.
Fabrice Rose (2015)
10.1021/nn102845t
Antioxidant poly(lactic-co-glycolic) acid nanoparticles made with α-tocopherol-ascorbic acid surfactant.
C. Astete (2011)
10.1007/s11095-008-9786-x
Poly(Lactic-co-Glycolic) Acid as a Carrier for Imaging Contrast Agents
Amber L Doiron (2008)
10.2217/17435889.4.2.161
A novel biomaterial for osteotropic drug nanocarriers: synthesis and biocompatibility evaluation of a PLGA-ALE conjugate.
R. Pignatello (2009)
10.1007/s00441-012-1352-5
Biodegradable biomatrices and bridging the injured spinal cord: the corticospinal tract as a proof of principle
E. Joosten (2012)
10.1002/PI.5122
Amine‐modified poly(vinyl alcohol) as a novel surfactant to modulate size and surface charge of poly(lactide‐co‐glycolide) nanoparticles
C. Cella (2016)
10.1007/s11051-016-3449-3
Stimuli-sensitive nanoparticles for multiple anti-HIV microbicides
N. Giri (2016)
10.1002/ADV.21887
The influence of hydrophilic mPEG segment on formation, morphology, and properties of PCL‐mPEG microspheres
Y. He (2018)
10.4155/tde.14.91
PLGA: a unique polymer for drug delivery.
D. Kapoor (2015)
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