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Novel Drug Delivery Systems For Ocular Therapy: With Special Reference To Liposomal Ocular Delivery

Arpita Bhattacharjee, P. J. Das, Piya Adhikari, D. Marbaniang, Paulami Pal, S. Ray, B. Mazumder
Published 2019 · Medicine

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Delivery of drugs to eyes is a great challenge to researchers because of a number of barriers in the eye preventing the actual dose from reaching the site. A number of ophthalmic delivery systems have been developed in the past couple of years that are not only new but also safe and reliable and help to overcome all those barriers in the eye which are responsible for the very less bioavailability of drugs. In this review, we tried to focus on current research in ocular delivery of drug substances giving special emphasis to liposomal delivery system. A brief analysis of other novel ocular delivery systems, ocular physiology, and microbial sources of disease are also highlighted herein. We analyzed the various research findings for churning a general idea for novel ocular delivery system and its future use. The novel formulations may overcome the addressed problems of ophthalmic medication and comply with the quality assurance issues. The liposomal delivery is advantageous as they have the ability to entrap both hydrophobic and hydrophilic drugs and are suitable for delivery to both the anterior and posterior segment of the eye. Therefore, the use of this alternative approach is quite a necessity.
This paper references
10.1080/14786419.2014.983921
Isolation of a new triterpene derivative and in vitro and in vivo anticancer activity of ethanolic extract from root bark of Zizyphus nummularia Aubrev
Sarbani Dey Ray (2015)
10.1016/J.IJPHARM.2006.01.029
Study of an alginate/HPMC-based in situ gelling ophthalmic delivery system for gatifloxacin.
Zhidong Liu (2006)
10.3109/10717544.2010.483257
Solid lipid nanoparticles for ocular drug delivery
A. Seyfoddin (2010)
10.1016/j.xphs.2016.04.021
Thiolated α-Cyclodextrin: The Invisible Choice to Prolong Ocular Drug Residence Time.
M. Ijaz (2016)
10.1080/15583724.2014.971371
Recent Trends of Polymer-Protein Conjugate Application in Biocatalysis: A Review
Souvik Basak (2015)
10.1016/j.biomaterials.2011.10.076
Temperature sensitive contact lenses for triggered ophthalmic drug delivery.
H. J. Jung (2012)
ESTIMATION AND VALIDATION OF STABILITY INDICATING UV SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF GUAIFENESIN IN PRESENCE OF ITS DEGRADANT PRODUCTS
I. Bhattacharyya (2013)
10.1002/JPS.2600800113
Limits on optimizing ocular drug delivery.
J. Keister (1991)
10.22377/AJP.V4I1.118
Standarization and optimization of micromeretic properties of nimesulide for processing into a tablet dosage form by crystalo-co-agglomeration technology
S. Bhattacharyya (2010)
10.22036/ABCR.2015.10758
Simultaneous RP-HPLC and UV Spectroscopic Method Development and Validation for Estimation of Ibandronate Sodium in Bulk and Pharmaceutical Dosage Form
P. Bose (2015)
10.1016/S0169-409X(01)00105-3
Solid lipid nanoparticles: production, characterization and applications.
W. Mehnert (2001)
10.1016/J.JCONREL.2004.09.015
Poly(amidoamine) dendrimers as ophthalmic vehicles for ocular delivery of pilocarpine nitrate and tropicamide.
Th F Vandamme (2005)
10.1016/j.ejmech.2009.10.017
Designing dendrimers for ocular drug delivery.
G. Spataro (2010)
10.3109/03639041003610799
Preparation and characterization of puerarin–dendrimer complexes as an ocular drug delivery system
Wenjun Yao (2010)
10.5497/WJP.V2.I2.47
Ocular drug delivery systems: An overview.
Ashaben Patel (2013)
Exploring Protective Role of Ascorbic Acid on Busulfan-Induced Lipid Peroxidation
S. Ray (2011)
Cyclophosphamide-Induced Lipid Peroxidation and Changes in Cholesterol Content: Protective Role of Reduced Glutathione
Ray Supratim (2011)
10.1016/j.drudis.2007.10.021
Nanotechnology in ocular drug delivery.
S. Sahoo (2008)
10.1089/jop.2012.0069
Indomethacin-loaded solid lipid nanoparticles for ocular delivery: development, characterization, and in vitro evaluation.
Ketan Hippalgaonkar (2013)
10.2174/1874364101206010110
Diversity of Microbial Species Implicated in Keratitis: A Review
Elisabeth Karsten (2012)
10.1016/J.IJPHARM.2005.09.023
Preparation and evaluation of reverse-phase evaporation and multilamellar niosomes as ophthalmic carriers of acetazolamide.
Ahmed S. Guinedi (2005)
10.2174/1872211308666140926112000
Recent patents on ophthalmic nanoformulations and therapeutic implications.
Ann-Marie Ako-Adounvo (2014)
QSAR Modeling of Antimycobacterial Activities of N-Benzylsalicylamides and N-Benzylsalicylthioamides Derivatives against Mycobacterium kansasii CNCTC My (235/80) Using Topological Parameter
S. Ray (2011)
10.1016/J.EURPOLYMJ.2014.08.006
Poly(ester amides) (PEAs) – Scaffold for tissue engineering applications
Kajal Ghosal (2014)
10.1201/9781420008449.CH14
Lipid Nanoparticles (Solid Lipid Nanoparticles and Nanostructured Lipid Carriers) for Cosmetic, Dermal, and Transdermal Applications
E. Souto (2007)
10.3390/POLYM3010193
Recent Advances in Ocular Drug Delivery Systems
N. Kuno (2011)
10.2174/156720112801323125
Controlled and continuous release ocular drug delivery systems: pros and cons.
H. Abdelkader (2012)
10.1016/j.biomaterials.2010.01.113
Extended delivery of hydrophilic drugs from silicone-hydrogel contact lenses containing vitamin E diffusion barriers.
Cheng-Chun Peng (2010)
10.1016/S0378-5173(02)00080-7
Solid lipid nanoparticles (SLN) as ocular delivery system for tobramycin.
R. Cavalli (2002)
10.1128/AAC.00393-06
Calcineurin Promotes Infection of the Cornea by Candida albicans and Can Be Targeted To Enhance Fluconazole Therapy
C. Onyewu (2006)
10.1016/S0928-0987(02)00057-X
Eudragit RS100 nanosuspensions for the ophthalmic controlled delivery of ibuprofen.
R. Pignatello (2002)
Traditional herbal remedies for various ailments within the rural communities in the district of Bankura and Purulia
S K Ghosh (2013)
Simultaneous spectrophotometric assay for estimation of norfloxacin and metronidazole in tablets
S Basak (2010)
ANTIMYCOBACTERIAL ACTIVITIES OF N-BENZYLSALICYLAMIDES AND N- BENZYLSALICYLTHIOAMIDES DERIVATIVES AGAINST MYCOBACTERIUM TUBERCULOSIS CNCTC MY (331/ 88) AND MYCOBACTERIUM KANSASII CNCTC MY (6509/ 96): QSAR MODELING USING ELECTROTOPOLOGICAL STATE ATOM (E-STATE) PARAMETERS
S. Ray (2012)
10.2174/157340612801216210
A QSAR study of biphenyl analogues of 2-nitroimidazo-[2, 1-b] [1, 3]-oxazines as antitubercular agents using genetic function approximation.
S. Ray (2012)
ETORICOXIB-LOADED SOLID LIPID NANOPARTICLE DOSAGE FORM: FORMULATION, OPTIMIZATION, CHARACTERIZATION, STABILITY STUDYAND IN-VITRO IN-VIVO EVALUATION
S. Bhattacharyya (2015)
10.1016/j.xphs.2016.03.006
α-Lipoic Acid in Soluplus(®) Polymeric Nanomicelles for Ocular Treatment of Diabetes-Associated Corneal Diseases.
Fernando Alvarez-Rivera (2016)
Mathematical modeling of drug release profiles for modified hydrophobic HPMC based gels.
K. Ghosal (2012)
193–201
Nagarwal RC Oliveira L et al. Recent patents on ophthalmic Ako-Adounvo A-M (2016)
All rights reserved. Scopus® is a registered trademark of
B V Copyright © Elsevier (2013)
10.1016/j.drudis.2012.01.014
Contact lenses in ocular therapeutics.
Himanshu Gupta (2012)
Niosomes as carriers for ophthalmic drugs: in vitro/in vivo evaluation.
G. Perini (1996)
10.1016/j.ijpharm.2009.06.020
Liposome coated with low molecular weight chitosan and its potential use in ocular drug delivery.
N. Li (2009)
10.3109/08982104.2016.1167737
Design and evaluation of proniosomes as a carrier for ocular delivery of lomefloxacin HCl
R. Khalil (2017)
10.1128/AAC.03305-14
Cationic Liposomal Sodium Stibogluconate (SSG), a Potent Therapeutic Tool for Treatment of Infection by SSG-Sensitive and -Resistant Leishmania donovani
Roma Sinha (2014)
QSAR MODELING OF ALDOSE REDUCTASE INHIBITORY ACTIVITY OF FLAVONOID COMPOUNDS USING ELECTROTOPOLOGICAL STATE ATOM PARAMETER (E-STATE)
S. Ray (2013)
10.1016/j.ijpharm.2014.11.032
Cationic solid lipid nanoparticles enhance ocular hypotensive effect of melatonin in rabbit.
A. Leonardi (2015)
Nanostructured lipid carriers and their current application in current application in targeted drug delivery
P Jaiswal (2016)
10.1016/J.IJPHARM.2003.09.016
Vesicular systems in ocular drug delivery: an overview.
I. P. Kaur (2004)
10.1016/S0378-5173(01)00760-8
Chitosan nanoparticles: a new vehicle for the improvement of the delivery of drugs to the ocular surface. Application to cyclosporin A.
A. M. de Campos (2001)
10.3109/10717544.2014.898110
Nanostructured lipid (NLCs) carriers as a bioavailability enhancement tool for oral administration
Bharti Gaba (2015)
10.1155/2011/863734
Recent Applications of Liposomes in Ophthalmic Drug Delivery
G. P. Mishra (2011)
A Theoretical Study On Antimycobacterial Activities Of Nbenzylsalicylamides And N-Benzylsalicylthioamides Derivatives Against Mycobacterium Avium
S. Ray (2012)
10.3109/1061186X.2012.716845
Nanostructured lipid carriers system: Recent advances in drug delivery
M. A. Iqbal (2012)
All rights reserved. Scopus® is a registered trademark of Elsevier B.V. In vivo evaluation of anti-diarrheal activity of the rhizome of Nymphaea alba (Nymphaeaceae) (2012)
B V Copyright © Elsevier (2019)
Elsevier B.V. All rights reserved. Scopus® is a registered trademark of
© Copyright (2019)
Charusmriti A qsar study at AM1 semi empirical level of 1, 3-diaryl pyrazole derivatives as antitumor agents against human DU145 prostrate cancer cell line
S Ray (2012)
Synthesis and biological activity of succinimidobenzenesulfonyl oxopyrrolidine analogs as possible antineoplastic Agents
S Ray (2009)
10.1021/BC010102U
Polyester dendritic systems for drug delivery applications: design, synthesis, and characterization.
H. Ihre (2002)
10.2478/v10007-009-0030-y
Sterodin®, a novel immunostimulating drug: Some toxicological and pharmacological evaluations in vivo, and drug-lipid interaction studies in vitro
S. Ray (2009)
Document Type: Article Publication Stage: Final Source: Scopus
All rights reserved. Scopus® is a registered trademark of Elsevier B.V. Document Type: Article Publication Stage: Final Source
B V Copyright © Elsevier (2019)
10.1016/S1734-1140(10)70262-0
COX-2 as a target for cancer chemotherapy.
Nilanjan Ghosh (2010)
Evaluation of Protective role of Morin on Busulfan-induced Lipid Peroxidation
S. Ray (2011)
10.1590/S1984-82502011000400021
Alginate/hydrophobic HPMC (60M) particulate systems: new matrix for site-specific and controlled drug delivery
K. Ghosal (2011)
10.1016/j.ejpb.2015.02.013
Intracellular delivery of dendrimer triamcinolone acetonide conjugates into microglial and human retinal pigment epithelial cells.
S. Kambhampati (2015)
10.1128/CMR.13.4.662-685.2000
Fungal and parasitic infections of the eye.
S. Klotz (2000)
10.1016/j.colsurfb.2011.06.025
Nanostructured lipid carriers for triamcinolone acetonide delivery to the posterior segment of the eye.
J. Araújo (2011)
Design and development of insulin emulgel formulation for transdermal drug delivery and its evaluation.
M. Akram (2013)
QSAR modeling of antitmycobacterial activities of N-Benzylsalicylamides and N-Benzylsalicylthioamides derivatives against mycobacterium kansasii CNCTC my (6509/96) using stepwise and PLS method
S Ray (2012)
10.1002/wnan.1328
Nanogels for delivery, imaging and therapy.
Amal J Sivaram (2015)
10.2174/157018010792062786
Exploring QSAR of Flavonoids as Scavengers of Peroxynitrite Using Electrotopological State (E-State) Atom Parameter
S. Ray (2010)
Development and evaluation of nefopam transdermal matrix patch system in human volunteers.
P. De (2009)
10.1016/j.sjopt.2015.06.003
Candida parapsilosis corneal graft infection from a single eye center: Histopathologic report of 2 cases
H. Alkatan (2015)
10.1089/jop.2008.0031
Development of effective ocular preparations of antifungal agents.
I. P. Kaur (2008)
10.22037/IJPR.2010.793
Polymeric ocular nanosuspension for controlled release of acyclovir: in vitro release and ocular distribution
P. Dandagi (2009)
10.4137/OED.S4866
A European Perspective on Topical Ophthalmic Antibiotics: Current and Evolving Options
D. Brémond-Gignac (2011)
10.1177/1934578X1400900739
Advances in Herbal Medicine for Treatment of Ischemic Brain Injury
N. Ghosh (2014)
Potential aspects of chitosan as pharmaceutical excipient.
S. Ray (2011)
10.3109/13880209.2011.558515
Recent advances in herbal medicine for treatment of liver diseases
Nilanjan Ghosh (2011)
10.1211/0022357023691
Nanosuspensions: a promising drug delivery strategy
V. Patravale (2004)
10.1002/JPS.10227
Ocular tolerability of Eudragit RS100 and RL100 nanosuspensions as carriers for ophthalmic controlled drug delivery.
R. Pignatello (2002)
10.1016/j.ijpharm.2010.10.013
Nanostructured lipid carrier (NLC) coated with Chitosan Oligosaccharides and its potential use in ocular drug delivery system.
Q. Luo (2011)
Document Type: Review Publication Stage: Final Source: Scopus
10.3797/SCIPHARM.0807-10
Development and evaluation of a mucoadhesive nasal gel of midazolam prepared with Linum usitatissimum L. seed mucilage.
S. Basu (2009)
10.3109/10717544.2013.861883
Formulation and evaluation of Cyclosporin A emulgel for ocular delivery
Y. Shen (2015)
10.1016/j.ijpharm.2010.06.015
Self-assembled liquid crystalline nanoparticles as a novel ophthalmic delivery system for dexamethasone: Improving preocular retention and ocular bioavailability.
L. Gan (2010)
10.1016/j.ijpharm.2012.12.049
Promising ion-sensitive in situ ocular nanoemulsion gels of terbinafine hydrochloride: design, in vitro characterization and in vivo estimation of the ocular irritation and drug pharmacokinetics in the aqueous humor of rabbits.
S. Tayel (2013)
A Theoretical Study of Phenolic Antioxidants at AM1 Semi Empirical Levels
S. Ray (2012)
10.1002/(SICI)1521-3773(19990401)38:7<884::AID-ANIE884>3.0.CO;2-K
Dendrimers: From Design to Application-A Progress Report.
M. Fischer (1999)
10.3109/03639045.2012.665460
Development of solid lipid nanoparticles and nanostructured lipid carriers for improving ocular delivery of acyclovir
A. Seyfoddin (2013)
10.1016/j.xphs.2016.02.014
Self-Assembled Thermoresponsive Nanogels Prepared by Reverse Micelle → Positive Micelle Method for Ophthalmic Delivery of Muscone, a Poorly Water-Soluble Drug.
G. Wang (2016)
Document Type: Article Publication Stage: Final Access Type: Open Access Source: Scopus
10.1016/S0168-3659(00)00358-8
In vitro uptake of polystyrene microspheres: effect of particle size, cell line and cell density.
W. Zauner (2001)
Ocular Drug Delivery
B. Gilger (2016)
Terms and conditions Privacy policy
A Bose
10.3109/10715762.2011.574290
Antioxidant protection: A promising therapeutic intervention in neurodegenerative disease
Nilanjan Ghosh (2011)
Evaluation of Protective Effect of Reduced Glutathione on Flutamide-Induced Lipid Peroxidation and Changes in Cholesterol Content Using Common Laboratory Markers
S. Dey (2011)
Flutamide-induced Lipid Peroxidation: Protective Role of Water extract of Spirulina platensis
S. Ray (2012)
10.2174/138920007779815977
Ocular disposition, pharmacokinetics, efficacy and safety of nanoparticle-formulated ophthalmic drugs.
Hai-zhi Bu (2007)
10.1016/J.IJPHARM.2006.02.050
Cationic liposomes as potential carriers for ocular administration of peptides with anti-herpetic activity.
R. Cortesi (2006)
Development of difference spectroscopic method for the estimation of Aspirin in formulation using hydrotropy
I Bhattacharyya (2011)
10.1002/JPS.1023
Trends and developments in liposome drug delivery systems.
T. Lian (2001)
10.3109/03639045.2012.736515
Recent advances in ocular drug delivery
Djamila Achouri (2013)
10.1023/A:1020398624602
Design and Function of a Dendrimer-Based Therapeutic Nanodevice Targeted to Tumor Cells Through the Folate Receptor
A. Quintana (2004)
A QSAR Study of Antimycobacterial activities of N-Benzylsalicylamides and N- Benzylsalicylthioamides derivatives against Mycobacterium avium CNCTC My (330/88) using Electrotopological state atom (e-state) Parameters
Supratim Ray (2012)
10.1016/j.ejpb.2010.02.011
A poloxamer/chitosan in situ forming gel with prolonged retention time for ocular delivery.
T. Gratieri (2010)
NANOEMULSION AS A NOVEL OPHTHALMIC DELIVERY SYSTEM FOR ACETAZOLAMIDE
N. Morsi (2014)
Formulation and characterization of both hydrophilic and hydrophobic HPMC based hydrogels containing diclofenac potassium
Kajal Ghosal (2010)
QSAR Modeling of inhibitory activity of Flavonoids against Aldose reductase enzyme using Electrotopological state atom (e-state) Parameter
Supratim Ray (2012)
10.1007/s13596-013-0108-4
Central depressant activity of ethanol extract of Nymphaea alba rhizome in mice
A. Bose (2013)
All rights reserved. Scopus® is a registered trademark of Elsevier B
B V Copyright © Elsevier (2011)
In-Situ Gelling System : A Novel Approach for Ocular Drug Delivery
Gourav Rajoria (2012)
10.1007/s11095-008-9694-0
Recent Perspectives in Ocular Drug Delivery
Ripal Gaudana (2008)
10.1208/aapsj060326
Optimization of chlorphenesin emulgel formulation
M. I. Mohamed (2008)
10.1016/j.nano.2012.03.004
Nanoliposomal minocycline for ocular drug delivery.
James M. Kaiser (2013)
10.2174/157016311796799062
20 Years of Lipid Nanoparticles (SLN & NLC): Present State of Development & Industrial Applications
R. Mueller (2011)
All rights reserved. Scopus® is a registered trademark of Elsevier B.V. Document Type: Article Publication Stage: Final Access Type: Open Access Source
B V Copyright © Elsevier (2019)
Exploring the antiperoxidative potential of morin on cyclophosphamide and flutamide-induced lipid peroxidation and changes in cholesterol profile in rabbit model.
S. Ray (2010)
10.1038/nrd1632
Recent advances with liposomes as pharmaceutical carriers
V. Torchilin (2005)
Document Type: Review Publication Stage: Final Access Type: Open Access Source: Scopus
10.1016/S0378-5173(97)00362-1
Properties of acyclovir-containing liposomes for potential ocular delivery
S. Law (1998)
10.2174/156720108785915087
Solid lipid nanoparticles and nanostructured lipid carriers--innovative generations of solid lipid carriers.
S. Shidhaye (2008)
All rights reserved. Scopus® is a registered trademark of
© Copyright (2019)
10.3109/21691401.2014.909822
Nanostructured lipid carriers and their current application in targeted drug delivery
Piyush Jaiswal (2016)
A Theoretical Study Of 1, 1-Diphenyl-2-Picrylhydrazyl (Dpph) Radical Scavenging Activities Of Flavonoids Using Electrotopological State Atom (E-State) Parameters
S. Ray (2012)
10.1081/DDC-120003445
Ocular Preparations: The Formulation Approach
Indu Pal Kaur (2002)
10.1016/j.jsps.2013.07.003
Design of liposomal colloidal systems for ocular delivery of ciprofloxacin.
E. Taha (2014)
10.1016/j.drudis.2007.11.002
Current and future ophthalmic drug delivery systems. A shift to the posterior segment.
Eva M. del Amo (2008)
10.3109/08830180903437212
Mechanisms and Efficacy of Immunobiologic Therapies for Inflammatory Bowel Diseases
Nilanjan Ghosh (2010)
10.1021/BC010103M
Polyester dendritic systems for drug delivery applications: in vitro and in vivo evaluation.
O. L. Padilla De Jesús (2002)
10.1590/S1984-82502013000400028
Effect of cross-linked biodegradable polymers on sustained release of sodium diclofenac-loaded microspheres
A. Saha (2013)
10.1186/s12906-015-0942-7
Pharmacological basis of the use of the root bark of Zizyphus nummularia Aubrev. (Rhamnaceae) as anti-inflammatory agent
S. Ray (2015)
FLURBIPROFEN LOADED SOLID LIPID NANOPARTICLES, FORMULATION AND OPTIMIZATION BY USING RESPONSE SURFACE METHODOLOGY SUBHRA
S. Bhattacharyya (2012)
20 years of lipid nanoparticles (SLN and NLC): present state of development and industrial applications.
R. Mueller (2011)
Exploring the Protective Role of Water Extract of Spirulina platensis on Flutamide-Induced Lipid Peroxidation Using 4-Hydroxy Nonenal and Nitric Oxide as Model Markers
S. Ray (2011)
10.1016/j.jep.2014.09.008
Reconstituted mother tinctures of Gelsemium sempervirens L. improve memory and cognitive impairment in mice scopolamine-induced dementia model.
P. Palit (2015)



This paper is referenced by
10.1080/15569527.2020.1823406
APRPG modified nanoliposome loaded with miR-146a-5p inhibitor suppressed choroidal neovascularization by targeting endothelial cells.
L. Li (2020)
10.1007/s40123-020-00257-7
Therapies Based on Nanoparticles for Eye Drug Delivery
Alejandra Meza-Ríos (2020)
Novel approaches for ocular drug delivery: A review
A. Singh (2019)
10.1016/j.ijpharm.2020.119895
Formulation of nanoliposome-encapsulated bevacizumab (Avastin): Statistical optimization for enhanced drug encapsulation and properties evaluation.
Maryam Malakouti-Nejad (2020)
10.3389/fbioe.2020.00764
An in situ Gelling System Based on Methylcellulose and Tranilast Solid Nanoparticles Enhances Ocular Residence Time and Drug Absorption Into the Cornea and Conjunctiva
Noriaki Nagai (2020)
10.1016/j.ijpharm.2020.119184
Comparison of thermosensitive in situ gels and drug-resin complex for ocular drug delivery: in vitro drug release and in vivo tissue distribution.
Yidan Wei (2020)
10.3390/polym12071519
Chitosan and its Derivatives for Ocular Delivery Formulations: Recent Advances and Developments
Alexandra Zamboulis (2020)
10.2174/1872211314666200127101149
Nanoformulations for ocular delivery of drugs - A Patent perspective.
Anmol Dogra (2020)
10.2174/1872211314666191224115211
Nano-Based Drug Delivery System: Recent Strategies for the Treatment of Ocular Disease and Future Perspective
Zufika Qamar (2019)
10.1016/j.foodchem.2020.127195
Biodegradable chitosan-sodium alginate-oleic acid nanocarrier promotes bioavailability and target delivery of lutein in rat model with no toxicity.
Veeresh Toragall (2020)
10.1016/j.cis.2020.102121
Potential application of liposomal nanodevices for non-cancer diseases: an update on design, characterization and biopharmaceutical evaluation.
F. Bayat (2020)
10.1080/10837450.2019.1616755
Thermosensitive hydrogel containing sertaconazole loaded nanostructured lipid carriers for potential treatment of fungal keratitis
N. Tavakoli (2019)
10.1016/j.colsurfa.2019.124071
Development and optimization of besifloxacin hydrochloride loaded liposomal gel prepared by thin film hydration method using 32 full factorial design
Arpita Bhattacharjee (2020)
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