Online citations, reference lists, and bibliographies.
← Back to Search

Volumetry: An Alternative To Assess Therapy Response For Malignant Pleural Mesothelioma?

T. Frauenfelder, M. Tutic, W. Weder, R. Götti, R. Stahel, B. Seifert, I. Opitz
Published 2011 · Medicine

Cite This
Download PDF
Analyze on Scholarcy
The purpose of our study was to assess robustness of volumetric measurement of malignant pleural mesothelioma (MPM) before and after chemotherapy to modified RECIST (response evaluation criteria in solid tumours) criteria. 30 patients with digitally available chest computed tomography (CT) scans before and after three cycles of chemotherapy were included. Three readers independently assessed tumour response using two different methods: 1) the modified RECIST criteria; and 2) the tumour volumetric approach using dedicated software (Myrian®; Intrasense, Paris, France). Inter-rater reliability of unidimensional and volumetric measurements was assessed using intraclass correlation. Tumour response classification for modified RECIST was compared to the volumetric approach applying unidimensional RECIST volumetric equivalent criteria. The determination of unidimensional tumour measurement (RECIST) revealed a low inter-rater reliability (0.55) and a low interobserver agreement for tumour response classification (general &kgr; 0.33). Only 14 patients were classified equally. A high inter-rater reliability (0.99) and interobserver agreement (general &kgr; 0.9) were found for absolute tumour volumes (volumetric measurements). 27 cases were classified equally. The number of cases classified as “stable disease” was higher for the volumetric approach using tumour-equivalent criteria compared to modified RECIST. Volumetric measurement of MPM on CT using Myrian® software is a reliable, reproducible and sensitive method to measure tumour volume and, thus, therapy response after induction chemotherapy.
This paper references
Measurement of mesothelioma on thoracic CT scans: a comparison of manual and computer-assisted techniques.
S. Armato (2004)
Effect of varying CT section width on volumetric measurement of lung tumors and application of compensatory equations.
H. Winer-Muram (2003)
The measurement of observer agreement for categorical data.
J. Landis (1977)
Reporting results of cancer treatment
A. Miller (1981)
Multicenter trial of neo-adjuvant chemotherapy followed by extrapleural pneumonectomy in malignant pleural mesothelioma.
W. Weder (2007)
Threedimensional evaluation of chemotherapy response in malignant pleural mesothelioma
G Ak (2009)
Living donor right liver lobes: preoperative CT volumetric measurement for calculation of intraoperative weight and volume.
A. Lemke (2006)
Computed tomography-based lung nodule volumetry--do optimized reconstructions of routine protocols achieve similar accuracy, reproducibility and interobserver variability to that of special volumetry protocols?
H. Bolte (2007)
Reporting results of cancer
AB Miller (1981)
Volumetrie von Metastasen beim Nierenzellkarzinom
A. Graser (2008)
Preoperative tumor volume is associated with outcome in malignant pleural mesothelioma.
H. Pass (1998)
Assessing intrarater, interrater and test-retest reliability of continuous measurements.
V. Rousson (2002)
Volume-Based Parameter of 18F-FDG PET/CT in Malignant Pleural Mesothelioma: Prediction of Therapeutic Response and Prognostic Implications
H. Lee (2010)
Computed tomography features in malignant pleural mesothelioma and other commonly seen pleural diseases.
M. Metintas (2002)
New Guidelines to Evaluate the Response to Treatment in Solid Tumors.
P. Therasse (2000)
Preoperative Liver Volumetry: How Does the Slice Thickness Influence the Multidetector Computed Tomography- and Magnetic Resonance-Liver Volume Measurements?
C. Reiner (2009)
New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada.
P. Therasse (2000)
intraoperative weight and volume
CS Reiner (2006)
Modeling of mesothelioma growth demonstrates weaknesses of current response criteria.
G. Oxnard (2006)
Modified RECIST criteria for assessment of response in malignant pleural mesothelioma.
M. Byrne (2004)
Therapy response in malignant pleural mesothelioma-role of MRI using RECIST, modified RECIST and volumetric approaches in comparison with CT
C. Plathow (2008)
Multicenter trial of neoadjuvant chemotherapy followed by extrapleural pneumonectomy in malignant pleural mesothelioma
W Weder (2007)
Three-dimensional evaluation of chemotherapy response in malignant pleural mesothelioma.
G. Ak (2010)
[Volumetry of metastases from renal cell carcinoma: comparison with the RECIST criteria].
A. Graser (2008)

This paper is referenced by
Volumetric assessment in malignant pleural mesothelioma.
David J Murphy (2017)
Influence of Sinogram-Affirmed Iterative Reconstruction on Computed Tomography–Based Lung Volumetry and Quantification of Pulmonary Emphysema
Stephan Baumueller (2016)
Pleural thickness after neoadjuvant chemotherapy is a prognostic factor in malignant pleural mesothelioma
M. Hashimoto (2019)
Detection, modeling and matching of pleural thickenings from CT data towards an early diagnosis of malignant pleural mesothelioma
Kraisorn Chaisaowong (2014)
Disease volumes as a marker for patient response in malignant pleural mesothelioma.
Z. Labby (2013)
Value of contrast CT in combination with PET/CT in mesothelioma staging: Optimal protocol for initial assessment
Mohamed Houseni (2017)
Therapeutic response assessment using 3D ultrasound for hepatic metastasis from colorectal cancer: Application of a personalized, 3D-printed tumor model using CT images
Ye Ra Choi (2017)
Flattening of the Lung Surface with Temporal Consistency for the Follow-Up Assessment of Pleural Mesothelioma
Peter Faltin (2016)
Specimen weight and volume: important predictors of survival in malignant pleural mesothelioma.
Diana Y. Kircheva (2016)
The Prognostic Role of TNM Staging Compared With Tumor Volume and Number of Pleural Sites in Malignant Pleural Mesothelioma.
C. Proto (2019)
A New Prognostic Score Supporting Treatment Allocation for Multimodality Therapy for Malignant Pleural Mesothelioma: A Review of 12 Years’ Experience
I. Opitz (2015)
Deep convolutional neural networks for the automated segmentation of malignant pleural mesothelioma on computed tomography scans
E. Gudmundsson (2018)
Malignant pleural mesothelioma: new treatments, new hopes?
A. Scherpereel (2017)
Imaging in pleural mesothelioma: A review of the 14th International Conference of the International Mesothelioma Interest Group.
S. Armato (2019)
Malignant pleural mesothelioma segmentation from thoracic CT scans
Wael Brahim (2017)
BIBLIOGRAPHIC REVIEW July 2016 Third Consensus Conference on Malignant Pleural Mesothelioma: State-of-the-art and recommendations
Elevated Circulating Activin A Levels in Patients With Malignant Pleural Mesothelioma Are Related to Cancer Cachexia and Reduced Response to Platinum-based Chemotherapy.
Juuso Paajanen (2019)
Variability of tumor area measurements for response assessment in malignant pleural mesothelioma.
Z. Labby (2013)
Initial Analysis of the International Association For the Study of Lung Cancer Mesothelioma Database
V. Rusch (2012)
A Multimodality Imaging Review of Malignant Pleural Mesothelioma Response Assessment.
Anna K. Nowak (2011)
Dynamic contrast-enhanced CT for the assessment of tumour response in malignant pleural mesothelioma: a pilot study
Eyjolfur Gudmundsson (2018)
Manual contouring based volumetric evaluation for colorectal cancer with liver limited metastases: a comparison with RECIST.
W. Fang (2013)
A comparison between MRI and CT in the assessment of primary tumour volume in mesothelioma.
S. Tsim (2020)
Medical imaging in personalised medicine: a white paper of the research committee of the European Society of Radiology (ESR)
European Society of Radiology (2015)
Imaging in pleural mesothelioma: A review of the 12th International Conference of the International Mesothelioma Interest Group.
S. Armato (2015)
British Thoracic Society Guideline for the investigation and management of malignant pleural mesothelioma
I. Woolhouse (2018)
The IASLC Mesothelioma Staging Project: Proposals for Revisions of the T Descriptors in the Forthcoming Eighth Edition of the TNM Classification for Pleural Mesothelioma
A. Nowak (2016)
Evaluation of inter-observer variability according to RECIST 1.1 and its influence on response classification in CT measurement of liver metastases.
M. Bellomi (2017)
Computed Tomography Advances in Oncoimaging.
Ashita Rastogi (2018)
Deep learning-based segmentation of malignant pleural mesothelioma tumor on computed tomography scans: application to scans demonstrating pleural effusion
E. Gudmundsson (2020)
Response evaluation in mesothelioma: Beyond RECIST.
Lin Cheng (2015)
Lung Volume Measurements as a Surrogate Marker for Patient Response in Malignant Pleural Mesothelioma
Zacariah E Labby (2013)
See more
Semantic Scholar Logo Some data provided by SemanticScholar