← Back to Search
Improving HIV Service Delivery For People Who Inject Drugs In Kazakhstan: Study Protocol For The Bridge Stepped-wedge Trial
Tara McCrimmon, L. Gilbert, T. Hunt, A. Terlikbayeva, Elwin Wu, M. Darisheva, Sholpan Primbetova, Azamat Kuskulov, A. Davis, A. Dasgupta, B. Schackman, Lisa R. Metsch, Daniel J Feaster, B. Baiserkin, N. El-Bassel
Published 2019 · Medicine
Save to my Library
Download PDFAnalyze on Scholarcy
BackgroundPeople who inject drugs (PWID) in Kazakhstan face many barriers to HIV testing as well as to accessing HIV care, to retention in HIV care, and to initiating and adhering to anti-retroviral treatment (ART). Needle and syringe programs (NSPs) are an opportune setting for integrated interventions to link PWID to HIV care.MethodsThis Hybrid Type II study employs a stepped-wedge design to evaluate both effectiveness and implementation outcomes of Bridge, an intervention to identify, test, and link HIV-positive PWID to HIV care. The study is conducted at 24 NSPs in three different regions of Kazakhstan, to assess outcomes on the individual, organizational, and policy levels.DiscussionThis trial responds to an identified need for new models of HIV service delivery for PWID through harm reduction settings.Trial registrationNCT02796027 on June 10, 2016.
This paper references
HIV Cascade Framework
Mills SFC (2015)
HIV Treatment Outcomes Among HIV-Infected, Opioid-Dependent Patients Receiving Buprenorphine/Naloxone Treatment within HIV Clinical Care Settings: Results From a Multisite Study
F. Altice (2011)
Scaling up HIV prevention efforts targeting people who inject drugs in Central Asia: a review of key challenges and ways forward.
A. Boltaev (2013)
'It's risky to walk in the city with syringes': understanding access to HIV/AIDS services for injecting drug users in the former Soviet Union countries of Ukraine and Kyrgyzstan
N. Spicer (2011)
Adherence to Antiretroviral Therapy Among HIV-Infected Drug Users: A Meta-Analysis
M. Malta (2008)
HIV treatment outcomes among people who inject drugs in Victoria, Australia
N. Walsh (2014)
A call for differentiated approaches to delivering HIV services to key populations
V. Macdonald (2017)
Directly observed antiretroviral therapy improves adherence and viral load in drug users attending methadone maintenance clinics: a randomized controlled trial.
K. Berg (2011)
Uptake of needle and syringe program services in the Kyrgyz Republic: Key barriers and facilitators.
A. Deryabina (2017)
Highly active antiretroviral therapy and survival in HIV-infected injection drug users.
E. Wood (2008)
Longitudinal community plasma HIV-1 RNA concentrations and incidence of HIV-1 among injecting drug users: prospective cohort study
E. Wood (2009)
Cost-effectiveness in health and medicine
M. Gold (1996)
Efficacy of a brief case management intervention to link recently diagnosed HIV-infected persons to care
L. Gardner (2005)
Fostering implementation of health services research findings into practice: a consolidated framework for advancing implementation science
L. Damschroder (2009)
Effects of a Couple-Based Intervention to Reduce Risks for HIV, HCV, and STIs Among Drug-Involved Heterosexual Couples in Kazakhstan: A Randomized Controlled Trial
Nabila El-Bassel (2014)
Interactions, Relationships and Social Structure. Man
RA Hinde (1976)
Accessing social networks with high rates of undiagnosed HIV infection: The social networks demonstration project.
Lisa W. Kimbrough (2009)
HIV Cascade Framework. Linkages
Sfc Mills (2015)
Enhanced HIV testing, treatment, and support for HIV-infected substance users.
N. Volkow (2010)
Interactions, Relationships and Social Structure
R. Hinde (1976)
Effectiveness-implementation Hybrid Designs: Combining Elements of Clinical Effectiveness and Implementation Research to Enhance Public Health Impact
G. Curran (2012)
HIV Treatment as Prevention: Systematic Comparison of Mathematical Models of the Potential Impact of Antiretroviral Therapy on HIV Incidence in South Africa
J. W. Eaton (2012)
Population size estimate of people who inject drugs (PWID) in the Republic of Kazakhstan. In: Almaty: Ministry of Health and Social Development of the Republic of Kazakhstan
L Y Ganina (2016)
A. Gibson (2000)
Provider barriers to prescribing HAART to medically-eligible HIV-infected drug users
A. Loughlin (2004)
Motivational interviewing. 3rd ed
W Miller (2012)
HIV Among Injection Drug Users and Their Intimate Partners in Almaty, Kazakhstan
N. El-Bassel (2013)
Reimagining HIV service delivery: the role of differentiated care from prevention to suppression
A. Grimsrud (2016)
H. V. D. Togt (2003)
Utilization of on-site primary care services by HIV-seropositive and seronegative drug users in a methadone maintenance program.
P. Selwyn (1993)
HIV Infection Care and Viral Suppression Among People Who Inject Drugs, 28 U.S. Jurisdictions, 2012-2013
D. Karch (2016)
HIV treatment cascade in MSM, people who inject drugs, and sex workers
K. Risher (2015)
An assessment of needle and syringe program (NSP) delivery models for people who inject drugs in the Kyrgyz Republic
AP Deryabina (2016)
HIV prevention, treatment, and care services for people who inject drugs: a systematic review of global, regional, and national coverage
Bradley M. Mathers (2010)
HIV transmission risk behaviors among HIV-infected persons who are successfully linked to care.
L. Metsch (2008)
Effectivenessimplementation hybrid designs: combining elements of clinical effectiveness and implementation research to enhance public health impact
GM Curran (2012)
Some heteroskedasticity-consistent covariance matrix estimators with improved finite sample properties☆
J. MacKinnon (1985)
Progress Towards the 90-90-90 Targets for Controlling HIV — China, 2018
Y. Zhao (2019)
A comparison of statistical approaches for physician-randomized trials with survival outcomes.
M. Stedman (2012)
Microcosting Quantity Data Collection Methods
K. Frick (2009)
HIV yesterday, today and tomorrow: implementation of national HIV response measures in the Republic of Kazakhstan
BC Baiserkin (2017)
Highly active antiretroviral therapy and survival in HIV-infected injection drug
E Wood (2008)
The urgency of providing comprehensive and integrated treatment for substance abusers with HIV.
N. Volkow (2011)
Design and analysis of stepped wedge cluster randomized trials.
M. Hussey (2007)
Are needle and syringe programmes associated with a reduction in HIV transmission among people who inject drugs: a systematic review and meta-analysis.
E. Aspinall (2014)
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations
Global epidemiology of injecting drug use and HIV among people who inject drugs: a systematic review
Bradley M. Mathers (2008)
An Assessment of Needle-Syringe Program for People Who Inject Drugs in the Kyrgyz Republic
A. Deryabina (2016)
This paper is referenced by
Anxiety and depression among women living with HIV in Kazakhstan.
K. Mishkin (2020)