Online citations, reference lists, and bibliographies.
← Back to Search

Bacteriophages As Antimicrobial Agents Against Major Pathogens In Swine: A Review

Jiancheng Zhang, Zhen Li, Zhenhui Cao, Lili Wang, Xiaoyu Li, Shuying Li, Y. Xu
Published 2015 · Biology, Medicine

Save to my Library
Download PDF
Analyze on Scholarcy Visualize in Litmaps
Share
Reduce the time it takes to create your bibliography by a factor of 10 by using the world’s favourite reference manager
Time to take this seriously.
Get Citationsy
In recent years, the development of antibiotic resistant bacteria has become a global concern which has prompted research into the development of alternative disease control strategies for the swine industry. Bacteriophages (viruses that infect bacteria) offer the prospect of a sustainable alternative approach against bacterial pathogens with the flexibility of being applied therapeutically or for biological control purposes. This paper reviews the use of phages as an antimicrobial strategy for controlling critical pathogens including Salmonella and Escherichia coli with an emphasis on the application of phages for improving performance and nutrient digestibility in swine operations as well as in controlling zoonotic human diseases by reducing the bacterial load spread from pork products to humans through the meat.
This paper references
10.1002/path.1700860214
OBSERVATIONS ON THE ALIMENTARY TRACT AND ITS BACTERIAL FLORA IN HEALTHY AND DISEASED PIGS.
H. W. Smith (1963)
An outbreak of Salmonella typhimurium infection in Delhi.
Bhatia Sl (1968)
10.1099/00221287-129-8-2659
Effectiveness of phages in treating experimental Escherichia coli diarrhoea in calves, piglets and lambs.
H. W. Smith (1983)
10.1097/00006454-198307000-00031
Hemorrhagic colitis associated with a rare Escherichia coli serotype.
L. Riley (1983)
10.4315/0362-028X-49.2.104
Homologous Bacteriophage Control of Pseudomonas Growth and Beef Spoilage 1, 2.
G. Greer (1986)
10.1099/00221287-133-5-1111
The control of experimental Escherichia coli diarrhoea in calves by means of bacteriophages.
H. Smith (1987)
10.1099/00221287-133-5-1127
Factors influencing the survival and multiplication of bacteriophages in calves and in their environment.
H. W. Smith (1987)
10.1093/CLINIDS/20.1.1
Escherichia coli O157:H7: clinical, diagnostic, and epidemiological aspects of human infection.
P. Tarr (1995)
10.1201/9781420042177
Poultry Meat Processing
C. Owens (2000)
10.1201/9781420042177-11
Microbiological pathogens: live poultry considerations
B. Hargis (2000)
10.1073/pnas.060024897
Correlation of enterohemorrhagic Escherichia coli O157 prevalence in feces, hides, and carcasses of beef cattle during processing.
R. Elder (2000)
H7 infection of calves by bacteriophages
T Waddell (2000)
Control of Escherichia coli O157: H7 infection of calves by bacteriophages
T Waddell (2000)
10.15232/S1080-7446(15)31633-8
REVIEW: Alternatives to Conventional Antimicrobials in Swine Diets1
J. Turner (2001)
10.1002/JCTB.438
Phages and their application against drug‐resistant bacteria
N. Chanishvili (2001)
10.1111/J.1745-4565.2001.TB00305.X
ATTEMPTS TO UTILIZE BACTERIOPHAGE TO COMBAT SALMONELLA ENTERICA SEROVAR ENTEMTIDIS INFECTION IN CHICKENS
Ian B. Sklar (2001)
The effect of bacteriophage treatment as a pre-harvest intervention strategy to reduce the rapid dissemination of Salmonella typhimurium in pigs
N Lee (2001)
10.1111/J.1574-6968.2002.TB11206.X
Characterization of a virulent bacteriophage specific for Escherichia coli O157:H7 and analysis of its cellular receptor and two tail fiber genes.
M. Morita (2002)
10.1016/S0168-1605(01)00710-3
Combined antimicrobial effect of nisin and a listeriophage against Listeria monocytogenes in broth but not in buffer or on raw beef.
G. Dykes (2002)
10.1128/AEM.69.1.170-176.2003
Coevolution of Bacteriophage PP01 and Escherichia coli O157:H7 in Continuous Culture
K. Mizoguchi (2003)
10.1046/j.1365-2672.94.s1.11.x
Verocytoxigenic Escherichia coli in animal faeces, manures and slurries
G. Duffy (2003)
10.1128/AEM.70.6.3417-3424.2004
Evaluation of a Cocktail of Three Bacteriophages for Biocontrol of Escherichia coli O157:H7
G. O'Flynn (2004)
10.1093/JAC/DKG483
Does the use of antibiotics in food animals pose a risk to human health? A critical review of published data.
I. Phillips (2004)
10.1637/7286-100404R
Use of Bacteriophages in Combination with Competitive Exclusion to Reduce Salmonella from Infected Chickens
H. Toro (2005)
10.1093/PS/84.4.655
Alternatives to antibiotics: utilization of bacteriophage to treat colibacillosis and prevent foodborne pathogens.
W. Huff (2005)
10.1093/PS/84.7.1141
Use of a specific bacteriophage treatment to reduce Salmonella in poultry products.
J. Higgins (2005)
10.1099/MIC.0.27849-0
Phage therapy: the Escherichia coli experience.
H. Brüssow (2005)
10.1080/01445340500112157
Oral treatment with bacteriophages reduces the concentration of Salmonella Enteritidis PT4 in caecal contents of broilers
L. Fiorentin (2005)
10.1016/J.VETMIC.2007.03.028
Isolation and characterization of nine bacteriophages that lyse O149 enterotoxigenic Escherichia coli.
N. Jamalludeen (2007)
Use of bacteriophage as an antimicrobial in food products
Kelly D. Bassett (2007)
Bacteriophages: Biology and Applications
E. Kutter (2007)
10.1016/j.resmic.2008.04.005
Diversity among the tailed-bacteriophages that infect the Enterobacteriaceae.
S. Casjens (2008)
10.1017/S1466252308001576
Bacteriophages for prophylaxis and therapy in cattle, poultry and pigs
R. Johnson (2008)
10.1128/AEM.00246-08
Microencapsulation of Bacteriophage Felix O1 into Chitosan-Alginate Microspheres for Oral Delivery
Yongsheng Ma (2008)
10.1128/AEM.02100-08
Prevalence and Impact of Bacteriophages on the Presence of Escherichia coli O157:H7 in Feedlot Cattle and Their Environment
Y. D. Niu (2009)
10.1111/j.1751-7915.2009.00089.x
Bacteriophage biocontrol in animals and meat products
R. Atterbury (2009)
10.1128/AEM.00785-09
Phage Therapy To Reduce Preprocessing Salmonella Infections in Market-Weight Swine
Samantha K Wall (2009)
10.1136/bmj.b4076
Escherichia coli O157
M. Locking (2009)
10.2807/ESE.14.10.19147-EN
An outbreak of Salmonella Typhimurium infections in Denmark, Norway and Sweden, 2008.
T. Bruun (2009)
10.1038/nrmicro2315
Bacteriophage resistance mechanisms
Simon J. Labrie (2010)
10.1016/S0140-6736(10)60963-4
Escherichia coli O157
H. Pennington (2010)
10.2527/jas.2010-2939
Effect of probiotic-, bacteriophage-, or organic acid-supplemented feeds or fermented soybean meal on the growth performance, acute-phase response, and bacterial shedding of grower pigs challenged with Salmonella enterica serotype Typhimurium.
E. Gebru (2010)
10.1201/B15805-9
Chapter Poultry meat inspection and grading
S. F. Bilgili (2010)
10.1111/j.1365-2672.2009.04549.x
Salmonella Enteritidis bacteriophage candidates for phage therapy of poultry
S. Sillankorva (2010)
A review of current knowledge on Salmonella control on-farm and within the processing plant relevant to the Northern Ireland pig industry
E. Magowan (2011)
10.1089/fpd.2010.0671
Evaluation of phage treatment as a strategy to reduce Salmonella populations in growing swine.
T. Callaway (2011)
10.1016/j.ijfoodmicro.2011.08.015
Application of a bacteriophage cocktail to reduce Salmonella Typhimurium U288 contamination on pig skin.
Steven P T Hooton (2011)
10.5713/ajas.2012.12253
Effect of Bacteriophage Supplementation on the Growth Performance, Nutrient Digestibility, Blood Characteristics, and Fecal Microbial Shedding in Growing Pigs
L. Yan (2012)
10.1186/2049-1891-4-35
Alternatives to antibiotics as growth promoters for use in swine production: a review
P. Thacker (2013)
10.1016/j.fm.2013.06.014
Salmonella bacteriophage diversity reflects host diversity on dairy farms.
A. M. Switt (2013)
10.1089/FPD.2013.1600
Isolation, characterization, and application of bacteriophages for Salmonella spp. biocontrol in pigs.
A. A. AlbinoLuiz (2014)
10.3855/jidc.3573
Bacteriophage therapy: a potential solution for the antibiotic resistance crisis.
Zhabiz Golkar (2014)
10.1089/fpd.2013.1600
Isolation, characterization, and application of bacteriophages for Salmonella spp. biocontrol in pigs.
L. F. T. Albino (2014)
10.1016/J.ANIFEEDSCI.2014.06.012
Bacteriophage and probiotics both enhance the performance of growing pigs but bacteriophage are more effective
Kyung-Nam Kim (2014)
10.1146/annurev-food-030713-092415
Phage therapy in the food industry.
Lorraine Endersen (2014)
Control of Escherichia coli O 157 : H 7 infection of calves by bacteriophages
T Waddell
Bacteriophages-Biology and applications. Boca Raton, FL: CRC; 2005
E Kutter



This paper is referenced by
10.3390/ani11030642
Towards Zero Zinc Oxide: Feeding Strategies to Manage Post-Weaning Diarrhea in Piglets
A. Bonetti (2021)
10.20535/IBB.2021.5.2.228970
Nosocomial Infections: Pathogenicity, Resistance and Novel Antimicrobials
Lin Wu (2021)
10.1128/MRA.00858-20
Complete Genome Sequences of Eight Phages Infecting Enterotoxigenic Escherichia coli in Swine
Alice Ferreira (2020)
10.22175/mmb.11180
Emerging Meat Processing Technologies for Microbiological Safety of Meat and Meat Products
M. Singh (2020)
10.1002/vms3.388
Influence of Salmonella specific bacteriophages (O1; S16) on the shedding of naturally occurring Salmonella and an orally applied Salmonella Eastbourne strain in bearded dragons (Pogona vitticeps)
Kevin Renfert (2020)
10.1111/tbed.13646
Application of phage therapy: Synergistic effect of phage EcSw (ΦEcSw) and antibiotic combination towards antibiotic-resistant Escherichia coli.
M. Easwaran (2020)
10.3390/microorganisms8050737
An Endolysin LysSE24 by Bacteriophage LPSE1 Confers Specific Bactericidal Activity against Multidrug-Resistant Salmonella Strains
Yifeng Ding (2020)
10.3389/fmicb.2020.609955
An Optimized Bacteriophage Cocktail Can Effectively Control Salmonella in vitro and in Galleria mellonella
J. Y. Nale (2020)
A Review of Enterotoxigenic Escherichia coli Infection in Piglets: Public Health Importance
Erwan Budi Hartadi (2020)
10.3390/pathogens8010019
Non-typhoidal Salmonella in the Pig Production Chain: A Comprehensive Analysis of Its Impact on Human Health
J. Campos (2019)
10.1007/978-3-030-26736-0_9
The Use of Bacteriophages in Animal Health and Food Protection
Katarzyna Kosznik-Kwaśnicka (2019)
Bioactivity and genome guided isolation of a novel antimicrobial protein from Thalassomonas viridans
S. Adams (2019)
10.3389/fmicb.2019.01035
Antimicrobial Effects on Swine Gastrointestinal Microbiota and Their Accompanying Antibiotic Resistome
Mohamed Zeineldin (2019)
10.3389/fmicb.2019.01491
Genomic Characterization of Jumbo Salmonella Phages That Effectively Target United Kingdom Pig-Associated Salmonella Serotypes
Anisha M. Thanki (2019)
10.1186/s40104-019-0352-7
Methodology and application of Escherichia coli F4 and F18 encoding infection models in post-weaning pigs
D. Luise (2019)
10.1055/a-0959-5528
The use of a salmonella bacteriophage in bearded dragons: application, passage time and reisolation.
Kevin Renfert (2019)
10.1007/978-3-319-71950-4_1
Probiotics and Prebiotics: An Overview on Recent Trends
G. Zoumpopoulou (2018)
10.1007/978-3-319-71950-4
Probiotics and Prebiotics in Animal Health and Food Safety
D. Gioia (2018)
10.1093/af/vfy001
Antimicrobial resistance in livestock: advances and alternatives to antibiotics
R. R. Marquardt (2018)
10.1016/j.aninu.2017.10.001
Intestinal challenge with enterotoxigenic Escherichia coli in pigs, and nutritional intervention to prevent postweaning diarrhea
Yawang Sun (2017)
10.1007/s00253-017-8591-z
A guard-killer phage cocktail effectively lyses the host and inhibits the development of phage-resistant strains of Escherichia coli
L. Yu (2017)
10.1016/B978-0-08-100593-4.00010-2
Current Challenges in Enhancing the Microbiological Safety of Raw Meat
K. Warriner (2017)
10.4014/jmb.1710.10049
Recent Trends in Salmonella Outbreaks and Emerging Technology for Biocontrol of Salmonella Using Phages in Foods: A Review.
Jun-Hyun Oh (2017)
10.1007/978-3-319-54051-1_2
Bacteriophage and Antimicrobial Resistance
S. A. Jassim (2017)
Évaluation in vivo de l’efficacité thérapeutique, de la résistance et la pharmacocinétique de la colistine sulfate lors du traitement de la diarrhée colibacillaire post sevrage chez le porc
Mohamed Rhouma (2017)
Escherichia coli O 157 : H 7 , Genetics Assessments , Prevalence and Importance for Health and Food Chain Supply
G. Riva (2017)
10.2903/j.efsa.2017.4666
EMA and EFSA Joint Scientific Opinion on measures to reduce the need to use antimicrobial agents in animal husbandry in the European Union, and the resulting impacts on food safety (RONAFA)
David Murphy (2017)
10.1007/s00203-017-1393-y
Current pathogenic Escherichia coli foodborne outbreak cases and therapy development
Shih-Chun Yang (2017)
10.3389/fmicb.2017.00957
Efficacy of Phage Therapy in Controlling Rabbit Colibacillosis and Changes in Cecal Microbiota
J. Zhao (2017)
10.4995/WRS.2017.6395
Effect of a lytic bacteriophage on rabbits experimentally infected with pathogenic Escherichia coli
J. Zhao (2017)
10.1186/s13028-017-0299-7
Post weaning diarrhea in pigs: risk factors and non-colistin-based control strategies
Mohamed Rhouma (2017)
10.5897/AJB2015.15023
An improved plating assay for determination of phage titer
L. Yang (2016)
See more
Semantic Scholar Logo Some data provided by SemanticScholar