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Parkinson's Disease And Somatosensory Evoked Potentials

P. Rossini, R. Traversa, P. Boccasena, G. Martino, F. Passarelli, L. Pacifici, G. Bernardi, P. Stanzione
Published 1993 · Psychology, Medicine

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We recorded somatosensory evoked potentials (SEPs) to median nerve stimulation from parietal and frontal districts in 32 patients with Parkinson's disease by evaluating latency/amplitude characteristics of the parietal P14-N20-P25 and of the frontal P20-N30-P40 wave complexes before and 10, 20, 30, and 60 minutes after subcutaneous administration of apomorphine chloride. The frontal complex N30-P40 was smaller than normal in 17 patients in baseline recordings. Following apomorphine, the parietal responses did not significantly vary in amplitude, but the frontal complex showed a remarkable amplitude potentiation in 22 of 32 patients (68.7%, p < 0.001), 19 of whom were also improving clinically. Amplitude potentiation was evident 10 minutes after apomorphine and faded away nearly in parallel with the end of its clinical efficacy. There were no SEP changes in three healthy controls after apomorphine.

This paper is referenced by
Somatosensory processing during movement observation in humans
S. Rossi (2002)
Vision of the body modulates processing in primary somatosensory cortex
M. Longo (2011)
Frontal phasic and oscillatory generators of the N30 somatosensory evoked potential
Ana-Maria Cebolla (2011)
Biochemical Markers of DBS-Induced Transition from “Off” to “On” State in Parkinsonian Patients
S. Galati (2005)
Increased cortical inhibition induced by apomorphine in patients with Parkinson's disease
L. Manfredi (1998)
Somatosensory evoked potentials during the ideation and execution of individual finger movements
P. Rossini (1996)
Deep brain stimulation of both subthalamic nucleus and internal globus pallidus restores intracortical inhibition in Parkinson's disease paralleling apomorphine effects: a paired magnetic stimulation study
M. Pierantozzi (2002)
Chapter 5 Somatosensory evoked responses
F. Mauguière (2003)
Median nerve somatosensory evoked potentials. Apomorphine-induced transient potentiation of frontal components in Parkinson's disease and in parkinsonism.
P. Rossini (1995)
The abnormality of N30 somatosensory evoked potential in idiopathic Parkinson's disease is unrelated to disease stage or clinical scores and insensitive to dopamine manipulations
M. Onofrj (1995)
Human subthalamic oscillatory dynamics following somatosensory stimulation
S. Elben (2018)
Reduction in amplitude of the subcortical low- and high-frequency somatosensory evoked potentials during voluntary movement: an intracerebral recording study
A. Insola (2004)
Amphetamine Effects on Striatal Neurons: Implications for Models of Dopamine Function
J. L. Haracz (1998)
Disappearance of frontal N30 component of median nerve stimulated SSEPs in two young children with abnormal striatal lesions
Yosuke Kato (2007)
Change in lateralization of the P22/N30 cortical component of median nerve somatosensory evoked potentials in patients with cervical dystonia after successful treatment with botulinum toxin A
P. Kaňovský (1998)
The effect of deep brain stimulation on the frontal N30 component of somatosensory evoked potentials in advanced Parkinson's disease patients
M. Pierantozzi (1999)
Effect of chronic pallidal deep brain stimulation on off period dystonia and sensory symptoms in advanced Parkinson’s disease
T. J. Loher (2002)
Pure phase-locking of beta/gamma oscillation contributes to the N30 frontal component of somatosensory evoked potentials
G. Cheron (2006)
The selective gating of the N30 cortical component of the somatosensory evoked potentials of median nerve is different in the mesial and dorsolateral frontal cortex: evidence from intracerebral recordings
P. Kaňovský (2003)
Potentiels évoqués en neurologie : réponses pathologiques et indications
F. Mauguière (2007)
Effects of enhanced somatosensory information on postural stability in older people and people with Parkinson’s disease
F. Qiu (2012)
ision of the body modulates processing in primary somatosensory cortex
atthew R. Longoa (2010)
SEPs N30 amplitude in Parkinson's disease and in pharmacologically induced rigidity: relationship with the clinical status
P. Stanzione (1997)
Short and long latency afferent inhibition in Parkinson's disease.
A. Sailer (2003)
Parkinson’s disease and lower limb somatosensory evoked potentials: Apomorphine-induced relief of the akinetic-rigid syndrome and vertex P37-N50 potentials
M. Tinazzi (1999)
Percutaneous tibial nerve stimulation produces effects on brain activity: Study on the modifications of the long latency somatosensory evoked potentials
E. Finazzi-Agrò (2009)
Statistical analysis of topographic maps of short-latency somatosensory evoked potentials in normal and parkinsonian subjects
F. Babiloni (1994)
Long-term practice effects on a new skilled motor learning: an electrophysiological study.
F. Fattapposta (1996)
Sensorimotor Integration during Rubber Hand Illusion in Normal Subjects and Subjects with Parkinson’s Disease
Reina Isayama (2018)
Preprogramming and control activity of bimanual self-paced motor task in Parkinson's disease
F. Fattapposta (2000)
Sensorimotor and cognitive involvement of the beta–gamma oscillation in the frontal N30 component of somatosensory evoked potentials
A. M. Cebolla (2015)
High-frequency oscillations in human posterior tibial somatosensory evoked potentials are enhanced in patients with Parkinson's disease and multiple system atrophy
K. Inoue (2001)
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