← Back to Search
True Incidence Of Vestibular Schwannoma?
Sven-Eric Stangerup, M. Tos, Jens Thomsen, P. Cayé‐Thomasen
Published 2010 · Medicine
Download PDFAnalyze on Scholarcy
BACKGROUND:The incidence of diagnosed sporadic unilateral vestibular schwannomas (VS) has increased, due primarily to more widespread access to magnetic resonance imaging. OBJECTIVE:To present updated epidemiological data on VS incidence, as well as patient age, hearing acuity, tumor size, and localization at diagnosis for the last 4 decades in an unselected population, with emphasis on developments in recent years. METHODS:From 1976 to 2008, 2283 new cases of VS were diagnosed and registered in a national database covering 5.0 to 5.5 million inhabitants. Incidence during the period, patient sex and age, data on hearing (pure tone average and speech discrimination), and tumor size at diagnosis were retrieved from the database. RESULTS:The incidence increased from 3.1 diagnosed VS per million per year in 1976 to a peak of 22.8 VS per million per year in 2004, which was followed by a decrease to 19.4 VS per million per year in 2008. Mean tumor size at diagnosis decreased from 30 mm in 1979 to 10 mm in 2008, whereas hearing acuity at diagnosis has improved over the years. CONCLUSION:After a steady increase over the last 4 decades, the incidence of vestibular schwannomas appears to have peaked and decreased in recent years, stabilizing at about 19 tumors per million per year. Whereas the sex ratio and age at diagnosis have remained grossly unchanged over the years, hearing has improved, and tumor size has decreased considerably.
This paper references
Epidemiology and clinical features of vestibular schwannoma in Manitoba
A M Frohlich (1993)
Incidence and growth pattern of vestibular schwannomas in a Danish county, 1977-98.
F. Mirz (2000)
Change in hearing during 'wait and scan' management of patients with vestibular schwannoma.
S-E Stangerup (2008)
Incidence of vestibular schwannomas
M. Tos (1999)
Asymptomatic acoustic neurilemoma.
J. R. Leonard (1970)
What is the real incidence of vestibular schwannoma?
M. Tos (2004)
J.What is the real incidence of vestibular schwannoma? Arch Otolaryngol Head Neck Surg
New and modified reporting systems from the consensus meeting on systems for reporting results in vestibular schwannoma.
J. Kanzaki (2003)
Epidemiology of primary intracranial neoplasms in Manitoba, Canada.
G. Sutherland (1987)
Epidemiology of primary tumours of the brain and spinal cord: a regional survey in southern England.
D. J. Barker (1976)
Incidence of vestibular schwannomas. Laryngoscope
M Tos (1999)
Incidence of acoustic neuromas.
M. Tos (1992)
Incidence of Vestibular Schwannoma and Neurofibromatosis 2 in the North West of England over a 10-year Period: Higher Incidence than Previously Thought
D. Evans (2005)
Undiagnosed acoustic neurinomas: a presentation of four cases
J Thomsen (1973)
Case-Control Study on Cellular and Cordless Telephones and the Risk for Acoustic Neuroma or Meningioma in Patients Diagnosed 2000–2003
L. Hardell (2005)
Increasing annual incidence of vestibular schwannoma and age at diagnosis.
Sven-Eric Stangerup (2004)
Epidemiology and clinical features of vestibular schwannoma in Manitoba, Canada.
A. Frohlich (1993)
Tumours of eighth cranial nerve
TT King (1976)
Early asymptomatic acoustic tumour
M Hardy (1936)
Epidemiology of acoustic neuromas.
M. Tos (1984)
EARLY ASYMPTOMATIC ACOUSTIC TUMOR: REPORT OF SIX CASES
Mary Hardy (1936)
Case-control study on cellular and cordless telephones and the risk for acoustic neuroma or meningioma in patients diagnosed
L Hardell (2000)
Occult schwannomas of the vestibular nerve.
T. Stewart (1975)
Cellular and cordless telephones and the risk for brain tumours
L. Hardell (2002)
SURGERY OF ACOUSTIC NEUROMAS
J. Thomsen (1977)
[Acoustic neurinoma. Neurosurgical treatment by suboccipital approach].
J. Overgaard (1981)
Increase of diagnosed vestibular schwannoma in Denmark.
M. Tos (1997)
Descriptive epidemiology of vestibular schwannomas.
J. Propp (2006)
The descriptive epidemiology of primary intracranial neoplasms: the Connecticut experience.
B. Schoenberg (1976)
Histopathology of 30 non-operated acoustic schwannomas
L. Eckermeier (2004)
This paper is referenced by
Incidence of vestibular schwannoma and incidental findings on the magnetic resonance imaging and computed tomography scans of patients from a direct referral audiology clinic.
B. Wong (2012)
When Should We Stop Scanning Older Patients with Vestibular Schwannomas?
Daniele Borsetto (2019)
Trends in acoustic neuroma management: a 20-year review of the oxford skull base clinic.
S. MacKeith (2013)
Long-term quality of life in patients with vestibular schwannoma: an international multicenter cross-sectional study comparing microsurgery, stereotactic radiosurgery, observation, and nontumor controls.
M. Carlson (2015)
Risk Factors of Acoustic Neuroma: Systematic Review and Meta-Analysis
Mantao Chen (2016)
Vertigo in Vestibular Schwannoma Patients Due to Other Pathologies.
Ronald Sahyouni (2017)
Radio Surgical Ablation of Acoustic Neuromas: A Unique Treatment Modality for an Elderly Woman
Jasmine A. Brathwaite (2016)
Assessment of costs in open surgery and stereotactic radiosurgery for vestibular schwannomas.
Hussam Abou-Al-Shaar (2018)
Seeing the forest for the trees.
Michael J. Link (2013)
Efficacy and Biomarker Study of Bevacizumab for Hearing Loss Resulting From Neurofibromatosis Type 2-Associated Vestibular Schwannomas.
J. Blakeley (2016)
Predictors of hearing outcomes following low-dose stereotactic radiosurgery in patients with vestibular schwannomas: A retrospective cohort review
Ryh-Hsin Lin (2017)
The prediction of the tumor size of a vestibular schwannoma by clinical performance and vestibular function tests
Y. Zhou (2018)
Fatigue in patients with vestibular schwannoma
Dhanushan Dhayalan (2019)
Paradoxical trends in the management of vestibular schwannoma in the United States.
Tsz Lau (2012)
Appendix : Exemplar Lateral and Central Skull Base Tumours Pathway
Risk factors for postoperative pneumonia after microsurgery for vestibular schwannoma
Chenghong Wang (2017)
Functional Regulation of the Neurofibromatosis 2 Tumor Suppressor Merlin
M. Pehrsson (2011)
Cystic Vestibular Schwannomas Respond Best to Radiosurgery
Greg Bowden (2017)
Machine learning approach for prediction of hearing preservation in vestibular schwannoma surgery
Dongchul Cha (2020)
Neurinome de l’acoustique et téléphonie mobile. Enseignements, limites et perspectives des études cliniques
Elisabeth Mornet (2013)
Mutation spectrum and differential gene expression in cystic and solid vestibular schwannoma
Z. Zhang (2014)
Historical perspective on evolution in management of lateral skull base tumors.
Theodore R. McRackan (2015)
Incidence trends of vestibular schwannomas in Denmark, Finland, Norway and Sweden in 1987–2007
S. Larjavaara (2011)
High Resolution Three-Dimensional Delayed Contrast MRI Detects Endolymphatic Hydrops in Patients With Vertigo and Vestibular Schwannoma.
Roxana Moayer (2018)
Growth of Primary and Remnant Vestibular Schwannomas: A Three-Year Follow-Up Study.
Y. Tomita (2015)
Outcome and toxicity analysis of single dose stereotactic radiosurgery in vestibular schwannoma based on the Koos grading system
D. Ruess (2020)
Diagnostic accuracy of high‐resolution T2‐weighted MRI vs contrast‐enhanced T1‐weighted MRI to screen for cerebellopontine angle lesions in symptomatic patients
M. Hentschel (2018)
MRI surveillance of vestibular schwannomas without contrast enhancement: Clinical and economic evaluation
D. Coelho (2018)
Temporomandibular disorder or not? A case report
Angel Álvarez-Arenal (2016)
Screening for vestibular schwannoma in the context of an ageing population.
Supriyo Basu (2019)
What factors influence treatment decision making in acoustic neuroma? Our experience on 103 cases
HClaudia Cassandro (2020)
Hearing aids in patients with vestibular schwannoma: Interest of the auditory brainstem responses
K. Reffet (2018)See more