Online citations, reference lists, and bibliographies.
← Back to Search

Cortical And Trabecular Bone Mineral Loss From The Spine And Hip In Long‐Duration Spaceflight

T. Lang, A. Leblanc, H. Evans, Y. Lu, H. Genant, A. Yu
Published 2004 · Biology, Medicine

Cite This
Download PDF
Analyze on Scholarcy
Share
We measured cortical and trabecular bone loss using QCT of the spine and hip in 14 crewmembers making 4‐ to 6‐month flights on the International Space Station. There was no compartment‐specific loss of bone in the spine. Cortical bone mineral loss in the hip occurred primarily by endocortical thinning.
This paper references
10.1017/cbo9780511815553.010
Strength
S. Beer (2002)
10.1016/S8756-3282(97)00072-0
Volumetric quantitative computed tomography of the proximal femur: precision and relation to bone strength.
T. Lang (1997)
Bone mineral and lean tissue loss after long duration space flight.
A. Leblanc (2000)
10.1097/00004424-200005000-00007
A physical model for dual-energy X-ray absorptiometry--derived bone mineral density.
H. Sievänen (2000)
10.1007/s002230050005
Quantitative Ultrasound Imaging of the Calcaneus: Precision and Variations During a 120-Day Bed Rest
P. Laugier (2000)
Quantitative ultrasound in bone status assessment.
D. Hans (1998)
Bone mineral density in upper and lower extremities during 12 months after spinal cord injury measured by peripheral quantitative computed tomography. Spinal Cord 38:26–32
P Frey-Rindova (2000)
10.1002/JBM.820281111
Correlations between orthogonal mechanical properties and density of trabecular bone: use of different densitometric measures.
J. Keyak (1994)
injury measured by peripheral quantitative computed tomography
TJ Beck (2001)
10.1016/S8756-3282(02)00785-8
Site- and compartment-specific changes in bone with hindlimb unloading in mature adult rats.
S. Bloomfield (2002)
10.1359/jbmr.2001.16.6.1108
Structural Adaptation to Changing Skeletal Load in the Progression Toward Hip Fragility: The Study of Osteoporotic Fractures
T. J. Beck (2001)
10.1097/00004728-199901000-00027
Assessment of vertebral bone mineral density using volumetric quantitative CT.
T. Lang (1999)
10.1152/JAPPL.2000.89.6.2158
Muscle volume, MRI relaxation times (T2), and body composition after spaceflight.
A. Leblanc (2000)
10.1088/0031-9155/44/3/017
Accuracy limits for the determination of cortical width and density: the influence of object size and CT imaging parameters.
S. Prevrhal (1999)
10.1097/00004728-199407000-00021
Calculation of Cross‐Sectional Geometry of Bone from CT Images with Application in Postmenopausal Women
T. A. Corcoran (1994)
10.1002/JBMR.5650050807
Bone mineral loss and recovery after 17 weeks of bed rest
A. Leblanc (1990)
10.1016/S0140-6736(00)02217-0
Effects of long-term microgravity exposure on cancellous and cortical weight-bearing bones of cosmonauts
L. Vico (2000)
10.1038/sj.sc.3100905
Bone mineral density in upper and lower extremities during 12 months after spinal cord injury measured by peripheral quantitative computed tomography
P. Frey-Rindova (2000)
10.1016/S8756-3282(97)00121-X
Morphological and structural characteristics of the proximal femur in human and rat.
C. Bagi (1997)
A computed tomographic investigation of the musculoskeletal system of the spine in humans after long-term spaceflight
V Oganov (1990)
puted tomographic investigation of the musculoskeletal system of the spine in humans after long - term spaceflight
TF Lang (1997)
10.1088/0031-9155/43/10/015
Accuracy of cortical and trabecular bone measurements with peripheral quantitative computed tomography (pQCT).
P. Augat (1998)
10.1046/j.1365-2362.2000.00719.x
Investigation of bone changes in microgravity during long and short duration space flight: comparison of techniques
I. McCarthy (2000)



This paper is referenced by
10.1117/12.810048
Raman spectroscopy of murine bone in response to simulated spaceflight conditions
Gurjit S. Mandair (2009)
10.1016/j.bone.2009.04.250
Bone fracture risk estimation based on image similarity.
W. Li (2009)
10.1007/s00774-015-0684-0
Assessment of osteoporosis using pelvic diagnostic computed tomography
Yee-Suk Kim (2015)
10.3389/fbioe.2014.00004
Investigation of the THOR Anthropomorphic Test Device for Predicting Occupant Injuries during Spacecraft Launch Aborts and Landing
J. Somers (2014)
10.1142/S0192415X14500104
Du-zhong (Eucommia ulmoides) prevents disuse-induced osteoporosis in hind limb suspension rats.
Y. Pan (2014)
10.1007/s00774-010-0201-4
Modeled microgravity and hindlimb unloading sensitize osteoclast precursors to RANKL-mediated osteoclastogenesis
R. Saxena (2010)
10.1016/j.gaitpost.2010.12.019
Postural instability caused by extended bed rest is alleviated by brief daily exposure to low magnitude mechanical signals.
J. Muir (2011)
10.1093/jrr/rru014
The combined effects of X-ray radiation and hindlimb suspension on bone loss
D. Xu (2014)
Risk of Hypoxia from the Exploration Atmosphere 1 Evidence Report : Risk of Hypobaric Hypoxia from the Exploration Atmosphere
J. Norcross (2015)
10.1007/s00198-010-1296-0
Genetic analysis of vertebral trabecular bone density and cross-sectional area in older men
J. Zmuda (2010)
Human Research Program Human Health and Countermeasures Element
Harlan J. Evans (2017)
The influence of the microstructure of bone on the sensation and signaling of osteocytes
(2007)
10.1016/J.AMJCARD.2006.09.103
Changes in bone mineral and body composition following coronary artery bypass grafting in men.
L. Miller (2007)
10.1002/jbmr.3414
Higher Dairy Food Intake Is Associated With Higher Spine Quantitative Computed Tomography (QCT) Bone Measures in the Framingham Study for Men But Not Women
Laura H van Dongen (2018)
10.1002/9780470942390.mo140071
Inducible Models of Bone Loss
Casey R. Doucette (2014)
10.1007/978-0-387-68164-1_2
Human Response to Space Flight
E. Baker (2008)
10.3389/fendo.2019.00060
Physical Activity and Bone Health: What Is the Role of Immune System? A Narrative Review of the Third Way
G. Lombardi (2019)
10.1115/1.4041164
Forecasting post-flight hip fracture probability using probabilistic modeling.
B. Lewandowski (2018)
10.1167/iovs.61.13.15
So-Called Lamina Cribrosa Defects May Mitigate IOP-Induced Neural Tissue Insult
A. Voorhees (2020)
10.1146/annurev-pathol-011110-130203
Disorders of bone remodeling.
Xu Feng (2011)
Artificial Gravity: Will it Preserve Bone Health on Long-Duration Missions?
J. Davis-Street (2005)
10.2514/6.IAC-05-B4.3.02
Five Years of NASA Research on ISS: A Continuing Saga
J. Uri (2005)
10.1016/J.JBIOMECH.2005.03.030
Hibernating bears as a model for preventing disuse osteoporosis.
S. Donahue (2006)
10.2514/6.IAC-06-A1.7.09
Exploration Health Risks: Probabilistic Risk Assessment
J. Rhatigan (2006)
Skeletal Recovery Following Long-Duration Spaceflight Missions as Determined by Preflight and Postflight DXA Scans of 45 Crew Members
J. Sibonga (2006)
10.1080/13547500601070842
Biochemical markers in preclinical models of osteoporosis
M. G. Sørensen (2007)
Reliability of Strength Testing using the Advanced Resistive Exercise Device and Free Weights
Kirk L. English (2008)
10.1249/MSS.0b013e3181a8c717
Muscle forces or gravity: what predominates mechanical loading on bone?
W. Kohrt (2009)
10.1201/B15626-20
Nanomedical Device and Systems Design in Space Applications
Frank Boehm (2013)
Spaceflight and hind limb unloading induce similar changes in electrical impedance characteristics of mouse gastrocnemius muscle.
M. Sung (2013)
10.1007/s00198-011-1578-1
An in vivo comparison of hip structure analysis (HSA) with measurements obtained by QCT
K. Ramamurthi (2011)
10.1016/B978-0-12-374602-3.00006-7
Chapter 6 – Essentials of Bone Biology: Assessment of Bone Architecture
Thomas Lang (2010)
See more
Semantic Scholar Logo Some data provided by SemanticScholar