Online citations, reference lists, and bibliographies.
← Back to Search

Synthesis, Surface Architecture And Biological Response Of Superparamagnetic Iron Oxide Nanoparticles For Application In Drug Delivery: A Review

M. Mahmoudi, A. Milani, P. Stroeve
Published 2010 · Materials Science

Save to my Library
Download PDF
Analyze on Scholarcy
Share
The biological and medical applications of superparamagnetic iron oxide nanoparticles (SPION) are increasing fast. Therefore, the reduction of toxicity of SPION, by using various surface coatings, has become a main research area. This review article presents a summary of recent research and data on well-characterised SPION with different surface coatings (dextran, polyvinyl alcohol (PVA), polyethylene glycol (PEG), polyethylene glycol fumarate (PEGF), alginate, chitosan, albumin) along with cytotoxicity evaluation methods for drug delivery. The effect of the surface architecture of SPION in different delivery conditions is also reviewed. Cytotoxicity data are found to vary depending on the size, size distribution and surface derivatisation of SPION. In turn, these parameters depend on the methods of particle synthesis. The use of coprecipitation, microemulsions, thermal decomposition and hydrothermal synthesis are among the reviewed synthesis methods. Statistical techniques used for the optimisation of synthesis parameters have also been addressed.
This paper references
10.1016/S0169-409X(97)00124-5
Protein release from alginate matrices.
W. Gombotz (1998)
Investigations in serum copper.
Holmberg Cg (1948)
10.1016/J.MSEC.2006.12.016
In situ synthesis and magnetic studies of iron oxide nanoparticles in calcium-alginate matrix for biomedical applications
M. A. Morales (2008)
10.1148/RADIOLOGY.197.2.7480707
MR imaging of phagocytosis in experimental gliomas.
C. Zimmer (1995)
10.1148/RADIOLOGY.169.2.3174987
Superparamagnetic iron oxide: enhanced detection of focal splenic tumors with MR imaging.
R. Weissleder (1988)
10.1006/JCIS.1998.5614
Size Tailoring of Magnetite Particles Formed by Aqueous Precipitation: An Example of Thermodynamic Stability of Nanometric Oxide Particles.
Vayssières (1998)
10.1016/S1359-0294(03)00019-0
Synthesis of nanomaterials in microemulsions: formation mechanisms and growth control ☆
M. A. López-Quintela (2003)
10.1016/J.JMMM.2004.08.007
Magnetic properties of α-Fe2O3 nanoparticle synthesized by a new hydrothermal method
S. Giri (2005)
10.1016/J.JCIS.2005.02.014
Preparation and properties of colloidal iron dispersions.
K. Butter (2005)
10.1002/PAT.987
A study of starch addition on burst effect and diameter of polyurethane microspheres containing theophylline
S. H. Emami (2008)
10.1046/j.1365-2222.2000.00879.x
The chromones: history, chemistry and clinical development. A tribute to the work of Dr R. E. C. Altounyan
Edwards (2000)
10.1006/JSRE.2000.6030
Clinical applications of magnetic drug targeting.
A. Lübbe (2001)
10.1016/J.REACTFUNCTPOLYM.2006.05.006
In situ preparation of magnetic chitosan/Fe3O4 composite nanoparticles in tiny pools of water-in-oil microemulsion
J. Zhi (2006)
10.1615/CRITREVTHERDRUGCARRIERSYST.V18.I1.20
Improved drug delivery using microemulsions: rationale, recent progress, and new horizons.
R. Bagwe (2001)
10.1346/CCMN.1991.0390104
Influence of Citrate on the Kinetics of Fe(II) Oxidation and the Formation of Iron Oxyhydroxides
G. Krishnamurti (1991)
10.1016/S0162-0134(99)00246-9
Nanoscale iron(III) oxyhydroxy aggregates formed in the presence of functional water-soluble polymers: models for iron(III) biomineralisation processes.
M. V. Nesterova (2000)
10.1016/J.INOCHE.2004.02.023
Shape controlled synthesis of PbS nanocrystals by a solvothermal-microemulsion approach
Jun-hua Xiang (2004)
10.1021/JA0380594
Synthesis of monodisperse superparamagnetic Fe/silica nanospherical composites.
P. Tartaj (2003)
10.1002/APP.1539
Characterization and application of high magnetic property chitosan particles
Xiaoning An (2001)
10.1016/S1357-2725(98)00098-3
Elastin: molecular description and function.
L. Debelle (1999)
10.1615/CRITREVTHERDRUGCARRIERSYST.V15.I4.20
Bioerodible polymers for ocular drug delivery.
A. Deshpande (1998)
10.1006/JCIS.1998.6053
Synthesis of Iron Oxide Nanoparticles Used as MRI Contrast Agents: A Parametric Study.
Babes (1999)
10.1021/IE0203835
Arsenic Removal Using Iron Oxide Loaded Alginate Beads
A. Zouboulis (2002)
Nanophase materials : synthesis, properties, applications
G. Hadjipanayis (1993)
10.1016/J.JMMM.2004.05.022
Preparation and properties of superparamagnetic nanoparticles with narrow size distribution and biocompatible
W. Jiang (2004)
10.1002/ANIE.200602866
Magnetic nanoparticles: synthesis, protection, functionalization, and application.
A. Lu (2007)
10.1016/S0022-1759(01)00433-1
Normal T-cell response and in vivo magnetic resonance imaging of T cells loaded with HIV transactivator-peptide-derived superparamagnetic nanoparticles.
C. H. Dodd (2001)
10.1007/BF00256663
Use of magnetic particles isolated from magnetotactic bacteria for enzyme immobilization
T. Matsunaga (2004)
10.1002/(SICI)1521-4095(199808)10:11<827::AID-ADMA827>3.0.CO;2-L
Soft and Wet Materials: Polymer Gels
Y. Osada (1998)
10.1039/B517351E
The synthesis of amine-capped magnetic (Fe, Mn, Co, Ni) oxide nanocrystals and their surface modification for aqueous dispersibility
Y. Li (2006)
10.1016/J.BBAGEN.2003.11.001
Studies on the nature of interaction of iron(III) with alginates.
K. Sreeram (2004)
10.1021/JA044419R
Ligand effect on the growth and the digestion of Co nanocrystals.
A. C. Samia (2005)
10.1002/(SICI)1097-4636(199901)44:1<116::AID-JBM13>3.0.CO;2-9
Studies on small (<350 microm) alginate-poly-L-lysine microcapsules. III. Biocompatibility Of smaller versus standard microcapsules.
R. Robitaille (1999)
10.5860/choice.29-2718
Iron Oxides in the Laboratory: Preparation and Characterization
U. Schwertmann (1991)
10.1021/CM061793C
Linking Hydrophilic Macromolecules to Monodisperse Magnetite (Fe(3)O(4)) Nanoparticles via Trichloro-s-triazine.
J. Xie (2006)
10.1016/S0025-5408(03)00129-6
One-step hydrothermal process to prepare highly crystalline Fe3O4 nanoparticles with improved magnetic properties
J. Wang (2003)
10.1002/AIC.10277
Combined experimental/numerical study on the precipitation of nanoparticles
H. Schwarzer (2004)
10.1016/J.JCIS.2007.01.081
Synthesis of bilayer oleic acid-coated Fe3O4 nanoparticles and their application in pH-responsive Pickering emulsions.
Q. Lan (2007)
10.1557/JMR.2002.0352
Continuous hydrothermal synthesis and crystallization of magnetic oxide nanoparticles
Linda J. Cote (2002)
10.1016/J.MATERRESBULL.2006.03.017
Template synthesis of highly crystalline and monodisperse iron oxide pigments of nanosize
K. Sreeram (2006)
10.1021/cr068445e
Magnetic iron oxide nanoparticles: synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications.
S. Laurent (2008)
10.1016/S1535-6108(02)00238-6
Integrin-mediated targeting of drug delivery to irradiated tumor blood vessels.
D. Hallahan (2003)
10.1021/JP904884Y
Multiphysics Flow Modeling and in Vitro Toxicity of Iron Oxide Nanoparticles Coated with Poly(vinyl alcohol)
M. Mahmoudi (2009)
10.1021/BC0155521
Magnetic resonance imaging of inducible E-selectin expression in human endothelial cell culture.
H. W. Kang (2002)
10.1524/zpch.2006.220.1.133
A Successful Strategy for the Production of Cationic Magnetoliposomes
M. de Cuyper (2006)
10.1021/JP993552G
Reverse Micelle Synthesis and Characterization of Superparamagnetic MnFe2O4 Spinel Ferrite Nanocrystallites
C. Liu (2000)
10.1021/JA016812S
Synthesis of highly crystalline and monodisperse maghemite nanocrystallites without a size-selection process.
T. Hyeon (2001)
10.1021/NL049562X
Controlled Assembly of Magnetic Nanoparticles from Magnetotactic Bacteria Using Microelectromagnets Arrays
Hakho Lee (2004)
10.1016/S0304-8853(00)01236-1
Preparation and characterization of affinity magnetoliposomes useful for the detection of antiphospholipid antibodies
F. M. Rocha (2001)
10.1002/ADMA.200305561
Sol–Gel Mediated Synthesis of Fe2O3 Nanorods†
K. Woo (2003)
10.5860/choice.37-0940
Advanced Inorganic Chemistry
F. Cotton (1999)
10.1021/LA010421+
Sonochemical synthesis of functionalized amorphous iron oxide nanoparticles
K. V. Shafi (2001)
10.1021/CM980742F
Electrochemical Synthesis for the Control of γ-Fe2O3 Nanoparticle Size. Morphology, Microstructure, and Magnetic Behavior
Cécile Pascal (1999)
10.3891/ACTA.CHEM.SCAND.02-0550
Investigations in Serum Copper. II. Isolation of the Copper Containing Protein, and a Description of some of its Properties.
C. Holmberg (1948)
10.1021/BC034160M
Physicochemical and biological characterization of polyethylenimine-graft-poly(ethylene glycol) block copolymers as a delivery system for oligonucleotides and ribozymes.
C. Brus (2004)
10.1016/J.POLYMER.2004.08.047
Preparation and magnetometric characterization of iron oxide-containing alginate/poly(vinyl alcohol) networks
Y. Nishio (2004)
10.1530/EJE.0.1450451
Successful treatment of resistant acromegaly with a growth hormone receptor antagonist.
W. M. Drake (2001)
10.1039/A802588F
Immobilization of Semiconductor Nanoparticles Formed in Reverse Micelles into Polyurea via In Situ Polymerization of Diisocyanates
S. Shiojiri (1998)
10.1021/ja806519m
pH controlled release of chromone from chromone-Fe3O4 nanoparticles.
Baodui Wang (2008)
Fibres, Films, Plastics and Rubbers: A Handbook of Common Polymers
W. J. Roff (1971)
10.1016/S0304-8853(00)01264-6
Glial brain tumor targeting of magnetite nanoparticles in rats
O. Mykhaylyk (2001)
10.1002/JMRI.1880070629
Uptake of dextran‐coated monocrystalline iron oxides in tumor cells and macrophages
A. Moore (1997)
10.1002/ADEM.200990035
Cytotoxicity and Cell Cycle Effects of Bare and Poly(vinyl alcohol)‐Coated Iron Oxide Nanoparticles in Mouse Fibroblasts
M. Mahmoudi (2009)
10.1021/JA026501X
Size-controlled synthesis of magnetite nanoparticles.
S. Sun (2002)
10.1016/J.CES.2006.11.029
Electrospray of ionic precursor solutions to synthesize iron oxide nanoparticles: Modified scaling law
S. Basak (2007)
10.1016/S0142-9612(03)00026-7
Implantable applications of chitin and chitosan.
E. Khor (2003)
10.1021/LA0009137
Resolving the Puzzle of Ferrofluid Dispersants
R. Tadmor (2000)
10.1006/JCIS.1996.0619
Colloidal Stability of Polymer Colloids with Different Interfacial Properties: Mechanisms
Ortega-Vinuesa (1996)
10.1016/J.SUPFLU.2007.09.033
Continuous hydrothermal synthesis of iron oxide and PVA-protected iron oxide nanoparticles
C. Xu (2008)
10.2174/157341308783591861
Magnetic Nanoparticles for Cancer Therapy
G. F. Goya (2008)
10.1021/JP972046T
Advances in the Preparation of Magnetic Nanoparticles by the Microemulsion Method
J. L. Pérez (1997)
10.1016/S0304-8853(00)01226-9
Structural and magnetic properties of nanoscale iron oxide particles synthesized in the presence of dextran or polyvinyl alcohol
H. Pardoe (2001)
10.1007/BFB0115170
Shape fluctuations of microemulsions droplets: Role of surfactant film bending elasticity
D. Langevin (1994)
10.2138/AM-1998-11-1228
Magnetite from magnetotactic bacteria; size distributions and twinning
B. Devouard (1998)
10.1021/MA9819438
Miniemulsion Polymerization with Cationic and Nonionic Surfactants: A Very Efficient Use of Surfactants for Heterophase Polymerization
K. Landfester (1999)
10.1016/J.BIOMATERIALS.2007.08.050
Iron oxide nanoparticles as a drug delivery vehicle for MRI monitored magnetic targeting of brain tumors.
B. Chertok (2008)
10.1002/anie.200800857
Drug-loaded superparamagnetic iron oxide nanoparticles for combined cancer imaging and therapy in vivo.
M. Yu (2008)
10.1146/ANNUREV.BIOENG.4.100101.132311
Bioengineering of therapeutic aerosols.
D. A. Edwards (2002)
10.1016/J.BIOMATERIALS.2005.03.039
The effect of RGD peptide-conjugated magnetite cationic liposomes on cell growth and cell sheet harvesting.
A. Ito (2005)
10.1073/pnas.152463399
Nanocrystal targeting in vivo
M. Akerman (2002)
10.1007/978-0-387-85600-1_20
APPLICATIONS OF MAGNETIC NANOPARTICLES IN BIOMEDICINE
C. Bárcena (2003)
10.1080/10408430701776680
Functionalized Magnetite Nanoparticles—Synthesis, Properties, and Bio-Applications
P. Majewski (2007)
10.1016/S0142-9612(01)00267-8
Surface modification of superparamagnetic magnetite nanoparticles and their intracellular uptake.
Y. Zhang (2002)
10.1016/J.IJPHARM.2006.10.006
Preparation and characterization of superparamagnetic iron oxide nanoparticles stabilized by alginate.
H. Ma (2007)
Polyvinyl alcohol; properties and applications
C. Finch (1973)
O'Brien's
Frank E. Miss Collector Buttolph (1959)
10.1016/J.JMMM.2005.01.064
Superparamagnetic nanoparticles for biomedical applications: Possibilities and limitations of a new drug delivery system
T. Neuberger (2005)
10.1016/J.COLSURFA.2004.12.019
Magnetic enhancement of iron oxide nanoparticles encapsulated with poly(d,l-latide-co-glycolide)
S. Lee (2005)
10.1021/ES0702768
Preparation of biotic and abiotic iron oxide nanoparticles (IOnPs) and their properties and applications in heterogeneous catalytic oxidation.
H. Jung (2007)
10.2174/0929867013372094
Advances in cancer therapy with plant based natural products.
A. Mukherjee (2001)
10.1007/S10971-007-1645-4
Design of oxide nanoparticles by aqueous chemistry
J. Jolivet (2008)
10.1016/J.PCRYSGROW.2008.08.003
Synthesis, properties, and applications of magnetic iron oxide nanoparticles
A. Teja (2009)
10.1016/j.jcis.2008.03.008
One-step synthesis and functionalization of hydroxyl-decorated magnetite nanoparticles.
S. Mondini (2008)
10.1080/10587259908028885
Nanophase Magnetic Materials: Synthesis and Properties
C. O'connor (1999)
10.1148/RADIOLOGY.214.2.R00FE19568
Tumoral distribution of long-circulating dextran-coated iron oxide nanoparticles in a rodent model.
A. Moore (2000)
[Magnetic resonance tomography of focal liver and spleen lesions. Experiences using ferrite, a new RES-specific MR contrast medium].
E. Rummeny (1988)
10.1186/1743-8977-6-1
Iron oxide nanoparticles induce human microvascular endothelial cell permeability through reactive oxygen species production and microtubule remodeling
P. L. Apopa (2008)
10.1016/J.JMMM.2003.12.252
In situ synthesis of magnetic MnZn-ferrite nanoparticles using reverse microemulsions
A. Košak (2004)
10.1016/J.SURFCOAT.2006.10.037
Hydrothermal growth and characterization of magnetite (Fe3O4) thin films
H. Zhu (2007)
10.1016/S0304-8853(03)00461-X
Contrast agents for MRI based on iron oxide nanoparticles prepared by laser pyrolysis
M. P. Morales (2003)
10.1016/J.BIOMATERIALS.2004.10.012
Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications.
A. Gupta (2005)
10.1016/J.MATERRESBULL.2006.04.037
Synthesis of magnetite octahedrons from iron powders through a mild hydrothermal method
Baodong Mao (2006)
10.1007/s11095-007-9513-z
Cytotoxicity of Paclitaxel in Biodegradable Self-Assembled Core-Shell Poly(Lactide-Co-Glycolide Ethylene Oxide Fumarate) Nanoparticles
Xuezhong He (2007)
10.1063/1.1419049
Microelectromagnets for the control of magnetic nanoparticles
C. Lee (2001)
10.1016/S0168-3659(00)00368-0
Evidence for receptor-mediated hepatic uptake of pullulan in rats.
Y. Kaneo (2001)
10.1021/LA9701642
Formation of TiO2 Nanoparticles in Reverse Micelles and Their Deposition as Thin Films on Glass Substrates
E. S. and (1997)
10.1016/S0142-9612(03)00237-0
Dextran and albumin derivatised iron oxide nanoparticles: influence on fibroblasts in vitro.
C. Berry (2003)
10.1002/SMLL.200600009
Methotrexate-immobilized poly(ethylene glycol) magnetic nanoparticles for MR imaging and drug delivery.
N. Kohler (2006)
10.1002/JBM.A.10117
Effect of composition of interpenetrating polymer network hydrogels based on poly(acrylic acid) and gelatin on tissue response: a quantitative in vivo study.
K. Burugapalli (2004)
10.2478/s11696-007-0014-7
A review of methods for synthesis of nanostructured metals with emphasis on iron compounds
A. Tavakoli (2007)
10.1021/CM049221K
Size- and Shape-Controlled Magnetic (Cr, Mn, Fe, Co, Ni) Oxide Nanocrystals via a Simple and General Approach
N. R. Jana (2004)
10.1016/J.JCIS.2006.02.022
Size control for two-dimensional iron oxide nanodots derived from biological molecules.
M. Tominaga (2006)
10.1006/JCIS.2001.7579
Synthesis and Characterization of Spherical Magnetite/Biodegradable Polymer Composite Particles.
S. A. Gómez-Lopera (2001)
10.1021/MA020028Q
Characterization of the Cross-Linked Structure of Fumarate-Based Degradable Polymer Networks
M. Timmer (2002)
10.1023/A:1016051316815
Formulation and Antitumor Activity Evaluation of Nanocrystalline Suspensions of Poorly Soluble Anticancer Drugs
E. Merisko-Liversidge (2004)
10.1021/JA074633Q
Kinetics of monodisperse iron oxide nanocrystal formation by "heating-up" process.
S. Kwon (2007)
10.1016/J.BIOMATERIALS.2003.08.014
In situ crosslinkable hyaluronan hydrogels for tissue engineering.
Xiao Zheng Shu (2004)
10.1002/1521-3773(20010504)40:9<1707::AID-ANIE17070>3.0.CO;2-F
pH-Responsive Polymer Microspheres: Rapid Release of Encapsulated Material within the Range of Intracellular pH**
D. Lynn (2001)
10.1002/ADMA.200701975
Controlled PEGylation of Monodisperse Fe3O4 Nanoparticles for Reduced Non‐Specific Uptake by Macrophage Cells
J. Xie (2007)
10.3109/10611869808997890
Superparamagnetic agents in magnetic resonance imaging: physicochemical characteristics and clinical applications. A review.
B. Bonnemain (1998)
10.1007/S12034-008-0016-2
Synthesis of iron oxide nanoparticles of narrow size distribution on polysaccharide templates
M. Nidhin (2008)
10.1021/MA001563Y
Synthesis and Characterization of Oligo(poly(ethylene glycol) fumarate) Macromer
Seongbong Jo (2001)
10.1021/MP0500014
Iron oxide nanoparticles for sustained delivery of anticancer agents.
Tapan Jain (2005)
10.1016/J.APSUSC.2006.05.023
Oleic acid coating on the monodisperse magnetite nanoparticles
L. Zhang (2006)
10.1021/LA950352X
Investigations into the Phase Behavior of Nonionic Ethoxylated Surfactants Using 2H NMR Spectroscopy
G. Dimitrova (1996)
10.1021/BC025625W
Low-pH-sensitive PEG-stabilized plasmid-lipid nanoparticles: preparation and characterization.
J. S. Choi (2003)
10.1007/S10853-005-3924-1
Synthesis of superparamagnetic Fe3O4/SiO2 composite particles via sol-gel process based on inverse miniemulsion
Zhihong Xu (2005)
10.2217/17435889.2.1.23
Recent advances on surface engineering of magnetic iron oxide nanoparticles and their biomedical applications.
A. Gupta (2007)
10.1021/bp010070p
Degradation of Partially Oxidized Alginate and Its Potential Application for Tissue Engineering
K. Bouhadir (2001)
10.1088/0957-4484/17/11/010
Structural and magnetic properties of uniform magnetite nanoparticles prepared by high temperature decomposition of organic precursors
A. G. Roca (2006)
10.1097/01.rli.0000255832.44443.e7
Fluorescent Bacterial Magnetic Nanoparticles as Bimodal Contrast Agents
M. Lisy (2007)
10.1016/S0142-9612(00)00151-4
Surface-immobilized dextran limits cell adhesion and spreading.
S. Massia (2000)
10.1021/BC034194U
Synthesis of ultrasmall superparamagnetic iron oxides using reduced polysaccharides.
K. G. Paul (2004)
10.1002/CHIN.200837219
Synthesis, Properties and Biomedical Applications of Magnetic Nanoparticles.
P. Tartaj (2008)
Uses and applications of microemulsions
B. K. Paul (2001)
10.1016/S0142-9612(02)00002-9
In situ crosslinking of a biomimetic peptide-PEG hydrogel via thermally triggered activation of factor XIII.
T. J. Sanborn (2002)
10.1021/JM051068Y
Synthesis, molecular characterization, and biological activity of novel synthetic derivatives of chromen-4-one in human cancer cells.
Vivek Barve (2006)
10.1021/CM991018F
Surface and Internal Spin Canting in γ-Fe2O3 Nanoparticles
M. Morales (1999)
10.1155/2007/94740
Superparamagnetic Iron Oxide Nanoparticles Coated with Galactose-Carrying Polymer for Hepatocyte Targeting
M. Yoo (2007)
10.1016/J.MSEC.2004.08.005
Magnetic studies of iron(III) nanoparticles in alginate polymer for drug delivery applications
P. V. Finotelli (2004)
10.1063/1.1507832
Detection of a micron-sized magnetic sphere using a ring-shaped anisotropic magnetoresistance-based sensor: A model for a magnetoresistance-based biosensor
M. M. Miller (2002)
10.1016/J.MATLET.2004.03.045
Properties of magnetite nanoparticles synthesized through a novel chemical route
D. Thapa (2004)
10.1088/0957-4484/20/5/055607
On the synthesis and magnetic properties of multiwall carbon nanotube-superparamagnetic iron oxide nanoparticle nanocomposites.
T. N. Narayanan (2009)
10.1021/JA0296935
Multifunctional gold nanoparticle-peptide complexes for nuclear targeting.
A. Tkachenko (2003)
10.1021/CR030063A
Chemistry and properties of nanocrystals of different shapes.
C. Burda (2005)
10.1021/LA0008636
Synthesis and Characterization of Silica-Coated Iron Oxide Nanoparticles in Microemulsion: The Effect of Nonionic Surfactants
S. Santra (2001)
10.1016/J.IJPHARM.2007.05.055
Potentialities of silica/alginate nanoparticles as hybrid magnetic carriers.
M. Boissière (2007)
10.1002/MARC.200500397
Binding and Sulfonation of Poly(acrylic acid) on Iron Oxide Nanoparticles: a Novel, Magnetic, Strong Acid Cation Nano‐Adsorbent
Sou-Yee Mak (2005)
10.1038/nbt876
Small-scale systems for in vivo drug delivery
David A. LaVan (2003)
10.1016/0169-409X(95)00025-3
Long circulating microparticulate drug carriers
S. Stolnik (1995)
10.1016/j.jcis.2009.04.046
Cell toxicity of superparamagnetic iron oxide nanoparticles.
M. Mahmoudi (2009)
10.1016/J.JMMM.2005.11.021
Preparation of a biocompatible magnetic film from an aqueous ferrofluid
C. Albornoz (2006)
10.1002/ADFM.200701317
Uniform Rattle-type Hollow Magnetic Mesoporous Spheres as Drug Delivery Carriers and their Sustained-Release Property†
Wenru Zhao (2008)
10.1016/S0927-7757(00)00633-6
Preparation of ultrafine silica- and PEG-coated magnetite particles
M. Butterworth (2001)
10.1016/J.JMMM.2005.02.020
Synthesis of magnetoliposomes with monodisperse iron oxide nanocrystal cores for hyperthermia
Marcela Gonzales (2005)
10.1016/S0092-8674(04)00130-8
Structure of the Human Transferrin Receptor-Transferrin Complex
Y. Cheng (2004)
10.1007/BF00357351
Preparation of colloidal Fe3O4 ultrafine particles in microemulsions
L. Liz (1994)
10.1039/A910201I
Sub-micrometer CoAl2O4 pigment particles : synthesis and preparation of coatings
J. Merikhi (2000)
10.1142/S0217984907013833
ORGANOMETALLIC SYNTHESIS OF NANOPARTICLES
C. Amiens (2007)
10.1080/00401706.2000.10486045
Uniform Design: Theory and Application
K. Fang (2000)
10.1016/j.biomaterials.2009.03.056
Differential proteomics analysis of the surface heterogeneity of dextran iron oxide nanoparticles and the implications for their in vivo clearance.
D. Simberg (2009)
10.1016/0167-577X(94)90077-9
Formation of γ-Fe2O3 by thermal decomposition of a mixture of Fe(II)- and FE(III)-oxalate salts
S. Music (1994)
10.1038/nrd1033
Effect of pegylation on pharmaceuticals
J. Harris (2003)
10.1073/PNAS.81.9.2752
Human transferrin: cDNA characterization and chromosomal localization.
F. Yang (1984)
10.1016/S0304-8853(00)01224-5
Synthesis and characterization of surfactant-coated superparamagnetic monodispersed iron oxide nanoparticles
D. Kim (2001)
10.1021/BM030056W
In vitro cytotoxicity of redox radical initiators for cross-linking of oligo(poly(ethylene glycol) fumarate) macromers.
J. Temenoff (2003)
10.1021/JP0351831
Preparation and Characterization of Monodisperse Fe Nanoparticles
D. Farrell (2003)
10.1016/S0304-8853(00)01255-5
Characterization and MRI study of surfactant-coated superparamagnetic nanoparticles administered into the rat brain
D. Kim (2001)
10.1109/INTMAG.2006.376279
Synthesis of Monodispersed Magnetite Particles From Different Organometallic Precursors
A. Roca (2006)
10.1126/SCIENCE.276.5320.1868
Large porous particles for pulmonary drug delivery.
D. Edwards (1997)
10.1148/RADIOL.2293021215
Characterization of biophysical and metabolic properties of cells labeled with superparamagnetic iron oxide nanoparticles and transfection agent for cellular MR imaging.
A. Arbab (2003)
10.1124/jpet.106.101915
Interaction of Functionalized Superparamagnetic Iron Oxide Nanoparticles with Brain Structures
F. Cengelli (2006)
10.1016/J.JMMM.2004.11.093
Synthesis of ferrofluid with magnetic nanoparticles by sonochemical method for MRI contrast agent
E. Kim (2005)
10.1016/J.JMMM.2005.01.038
Surface characterisation of dextran-coated iron oxide nanoparticles prepared by laser pyrolysis and coprecipitation
M. C. Bautista (2005)
10.1021/jp803016n
Optimal design and characterization of superparamagnetic iron oxide nanoparticles coated with polyvinyl alcohol for targeted delivery and imaging.
M. Mahmoudi (2008)
10.1080/02656730110108785
Magnetically mediated hyperthermia: current status and future directions
P. Moroz (2002)
10.1002/MRM.1910310305
Magnetic characterization of iron oxides for magnetic resonance imaging
Carl E. Sjøgren (1994)
10.1016/S0969-806X(98)00134-0
Crosslinking of recycled polyethylene by gamma and electron beam irradiation
E. Adem (1998)
10.1016/j.colsurfb.2009.02.015
Synthesis of aligned hematite nanoparticles on chitosan-alginate films.
K. Sreeram (2009)
10.1016/j.ijpharm.2007.11.036
Superparamagnetic iron oxide nanoparticles stabilized by alginate: pharmacokinetics, tissue distribution, and applications in detecting liver cancers.
H. L. Ma (2008)
10.1088/0957-4484/20/22/225104
An in vitro study of bare and poly(ethylene glycol)-co-fumarate-coated superparamagnetic iron oxide nanoparticles: a new toxicity identification procedure.
M. Mahmoudi (2009)
10.1007/BF00353047
Effects of surfactants on the precipitation and properties of colloidal particles from forced hydrolysis of FeCl3-HCl solution
K. Kandori (1995)
10.1021/LA970801O
Preparation of Ag/SiO2 nanosize composites by a reverse micelle and sol-gel technique
T. Li (1999)
10.1016/S0169-409X(00)00103-4
Microemulsion-based media as novel drug delivery systems
M. J. Lawrence (2000)
10.1016/J.CES.2006.02.032
Novel flow injection synthesis of iron oxide nanoparticles with narrow size distribution
G. Salazar-Alvarez (2006)
10.1002/cbic.200400174
Transport Of Surface‐Modified Nanoparticles Through Cell Monolayers
A. M. Koch (2005)
10.1021/JP900798R
Superparamagnetic Iron Oxide Nanoparticles with Rigid Cross-linked Polyethylene Glycol Fumarate Coating for Application in Imaging and Drug Delivery
M. Mahmoudi (2009)
10.1038/NMAT1251
Ultra-large-scale syntheses of monodisperse nanocrystals
J. Park (2004)
Long-circulating and target-specific nanoparticles: theory to practice.
S. Moghimi (2001)
10.1021/CM062948J
Influence of Iron Oleate Complex Structure on Iron Oxide Nanoparticle Formation
L. Bronstein (2007)
10.1021/JP9001516
Cytotoxicity of Uncoated and Polyvinyl Alcohol Coated Superparamagnetic Iron Oxide Nanoparticles
M. Mahmoudi (2009)
10.1039/B702538F
Antibody conjugated magnetic PLGA nanoparticles for diagnosis and treatment of breast cancer
Jaemoon Yang (2007)
Preparation of Poly(vinylpyrrolidone) Coated Iron Oxide Nanoparticles for Contrast Agent
L. Young (2005)



This paper is referenced by
10.2147/IJN.S190354
Effect of superparamagnetic nanoparticles coated with various electric charges on α-synuclein and β-amyloid proteins fibrillation process
N. Javdani (2019)
10.1201/B19543-25
Magnetic nanoparticles with multifunctional water-soluble polymers for bioapplications
Muhammad Irfan Majeed (2016)
10.1080/21691401.2019.1709855
Toxicity assessment of superparamagnetic iron oxide nanoparticles in different tissues.
R. Vakili-Ghartavol (2020)
10.1007/s10311-019-00893-x
Engineered nanostructured materials: benefits and risks
V. K. Yata (2019)
10.1071/CH14722
Synthesis, Characterization, and Nanocatalysis Application of Core–Shell Superparamagnetic Nanoparticles of Fe3O4@Pd
A. Cappelletti (2015)
10.1021/cr2002596
Assessing the in vitro and in vivo toxicity of superparamagnetic iron oxide nanoparticles.
M. Mahmoudi (2012)
10.1016/j.msec.2015.10.026
Effect of PEGylated superparamagnetic iron oxide nanoparticles (SPIONs) under magnetic field on amyloid beta fibrillation process.
Somayeh Mirsadeghi (2016)
10.1186/2193-8865-3-25
Separation of the defect-free Fe3O4-Au core/shell fraction from magnetite-gold composite nanoparticles by an acid wash treatment
H. Montazeri (2013)
10.1088/0953-8984/25/48/484003
Thermoseeds for interstitial magnetic hyperthermia: from bioceramics to nanoparticles.
A. Baeza (2013)
10.1016/j.cis.2011.04.003
Magnetic fluid hyperthermia: focus on superparamagnetic iron oxide nanoparticles.
S. Laurent (2011)
10.1021/cr1003166
Effect of nanoparticles on the cell life cycle.
M. Mahmoudi (2011)
10.1016/J.TRAC.2014.09.010
Proteomics analysis of the mode of antibacterial action of nanoparticles and their interactions with proteins
Hani Nasser Abdelhamid (2015)
10.1021/nn2021088
Toxicity evaluations of superparamagnetic iron oxide nanoparticles: cell "vision" versus physicochemical properties of nanoparticles.
M. Mahmoudi (2011)
10.1016/j.actbio.2017.07.007
Tumor targeting by lentiviral vectors combined with magnetic nanoparticles in mice.
E. Borroni (2017)
10.1007/978-3-319-30737-4_43
Iron Oxides and Their Silica Nanocomposites as Biocompatible Systems for Biomedical Applications
K. Gdula (2016)
10.1002/JCCS.201700110
Enhanced Visible Light Irradiation Photocatalytic Performance of MgFe2O4 After Growing with ZnO Nanoshell and Silver Nanoparticles
Y. Wang (2017)
10.1021/cn300196n
Influence of the physiochemical properties of superparamagnetic iron oxide nanoparticles on amyloid β protein fibrillation in solution.
M. Mahmoudi (2013)
10.1016/j.ijpharm.2018.12.024
Macrophage functionality and homeostasis in response to oligoethyleneglycol-coated IONPs: Impact of a dendritic architecture.
A. Casset (2019)
10.1039/c5nr06509g
Morphology evolution of single-crystalline hematite nanocrystals: magnetically recoverable nanocatalysts for enhanced facet-driven photoredox activity.
A. K. Patra (2016)
10.7567/JJAP.53.06JB03
Effect of ion-beam bombardment on microstructural and magnetic properties of Ni80Fe20/α-Fe2O3 thin films
C. Zheng (2014)
10.1016/j.actbio.2012.03.002
Magnetic targeting of surface-modified superparamagnetic iron oxide nanoparticles yields antibacterial efficacy against biofilms of gentamicin-resistant staphylococci.
G. Subbiahdoss (2012)
10.1016/j.biocel.2016.02.008
Understanding the nanoparticle-protein corona complexes using computational and experimental methods.
B. Kharazian (2016)
10.1039/c1nr10326a
Engineered nanoparticles for biomolecular imaging.
M. Mahmoudi (2011)
10.1016/j.eurpolymj.2019.109371
Bio-inspired encapsulation and functionalization of iron oxide nanoparticles for biomedical applications
Samson O. Aisida (2020)
Magnetic fl uid hyperthermia : Focus on superparamagnetic iron oxide nanoparticles
S. Laurent (2011)
10.1016/J.JMMM.2013.07.023
Structural and magnetic properties of γ-Fe2O3 nanostructured compacts processed by spark plasma sintering
P. Saravanan (2013)
10.36648/2471-9838.5.1.41
Superparamagnetic Nanoparticles Coated with Various Electric Charges and Structural Changes in α-Synuclein and β-Amyloid Proteins
Ahmadianpour (2019)
10.1080/1040841X.2019.1593101
Iron/iron oxide nanoparticles: advances in microbial fabrication, mechanism study, biomedical, and environmental applications
N. Ashraf (2019)
10.1016/j.ijpharm.2019.01.020
Preparation of multifunctional Janus nanoparticles on the basis of SPIONs as targeted drug delivery system
B. Shaghaghi (2019)
10.1016/J.COMPSCITECH.2015.08.010
High performance luminescent thermosetting waterborne hyperbranched polyurethane/carbon quantum dot nanocomposite with in vitro cytocompatibility
Satyabrat Gogoi (2015)
10.1007/s11051-015-3065-7
Synthesis and surface modification of magnetic nanoparticles for potential applications in sarcomas
S. Shahbazi (2015)
10.1016/J.COLSURFA.2012.05.039
Influence of morphology and surface exchange reaction on magnetic properties of monodisperse magnetite nanoparticles
Mengjie Song (2012)
See more
Semantic Scholar Logo Some data provided by SemanticScholar