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Nanomaterials For Cancer Therapies

Qing Zhou, L. Zhang, H. Wu
Published 2017 · Materials Science

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Abstract Cancer is one of the most deadly diseases in the world. In recent years, nanotechnology, as a unique technology, has been comprehensively applied in the therapy of cancer through diagnosis, imaging and theranostics. Additionally, with the emergence of advanced biomaterials which are capable of being applied in biomedical, research in cancer nanotechnology has made significant progress. Particularly, nanomaterials with dimensions below several hundred nanometers are intensively studied among these advanced biomaterials. In past decades, a number of organic and inorganic nanomaterials have emerged as novel tools for cancer diagnostics and therapeutics due to their unique characteristics, like their solubilization effect, drug protection, passive/active tumor targeting, controlled release of drugs which result in enhanced anticancer efficacy while reducing the side effects. In this review, we first provide a brief description of the key properties of nanomaterials, such as nanoparticle (NP) size, surface properties and tumor targeting. The major goal of this review is to summarize the achievements that have been made in the development of the application of nanomaterials for cancer therapies, along with a short description of their general characteristics and preparation of various kinds of nanoparticles.
This paper references
10.4103/0973-1482.95168
Nano cancer therapy strategies.
M. Tiwari (2012)
10.1002/smll.201002009
Graphene-based materials: synthesis, characterization, properties, and applications.
X. Huang (2011)
10.1016/j.jconrel.2008.09.086
Paclitaxel-loaded PEGylated PLGA-based nanoparticles: in vitro and in vivo evaluation.
F. Danhier (2009)
10.1007/s11095-006-9132-0
Micellar Nanocarriers: Pharmaceutical Perspectives
V. Torchilin (2006)
10.1586/14737140.7.4.415
Paclitaxel poliglumex (PPX, CT-2103): macromolecular medicine for advanced non-small-cell lung cancer
P. Bonomi (2007)
10.3109/03639045.2016.1173052
Novel gold nanoparticles coated with somatostatin as a potential delivery system for targeting somatostatin receptors
Ahmed A H Abdellatif (2016)
10.1038/srep10322
Curcumin-Encapsulated Polymeric Micelles Suppress the Development of Colon Cancer In Vitro and In Vivo
Xi Yang (2015)
10.1021/acs.biomac.5b00944
In Vitro and In Vivo Tumor Targeted Photothermal Cancer Therapy Using Functionalized Graphene Nanoparticles.
S. Kim (2015)
10.1016/S0168-3659(99)00248-5
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review.
H. Maeda (2000)
10.1016/j.biomaterials.2015.03.024
Allogenic dendritic cell and tumor cell fused vaccine for targeted imaging and enhanced immunotherapeutic efficacy of gastric cancer.
C. Li (2015)
10.1016/J.POLYMER.2013.07.074
Synthesis of magnetite/polyamino-ester dendrimer based on PCL/PEG amphiphilic copolymers via convergent approach for targeted diagnosis and therapy
S. Khoee (2013)
10.1039/c5nr07782f
A theranostic nrGO@MSN-ION nanocarrier developed to enhance the combination effect of sonodynamic therapy and ultrasound hyperthermia for treating tumor.
Yu-Wei Chen (2016)
10.1016/S0168-3659(98)00116-3
PLGA nanoparticles prepared by nanoprecipitation: drug loading and release studies of a water soluble drug.
T. Govender (1999)
10.1021/nn504905q
Polymeric Nanoparticles for Nonviral Gene Therapy Extend Brain Tumor Survival in Vivo
A. Mangraviti (2015)
10.2147/IJN.S92449
Reduced graphene oxide–silver nanoparticle nanocomposite: a potential anticancer nanotherapy
S. Gurunathan (2015)
10.1016/j.addr.2008.03.018
Magnetic nanoparticles in MR imaging and drug delivery.
C. Sun (2008)
10.1016/j.ijpharm.2016.03.022
Hydroxyl-modified magnetite nanoparticles as novel carrier for delivery of methotrexate.
Fatemeh Farjadian (2016)
10.1038/nnano.2007.387
Nanocarriers as an emerging platform for cancer therapy.
D. Peer (2007)
10.1039/C4PY01403K
Multifunctional pH-sensitive micelles for tumor-specific uptake and cellular delivery
Tiehong Yang (2015)
10.1016/j.ctrv.2008.04.003
Multi-functional nanocarriers to overcome tumor drug resistance.
L. Jabr-Milane (2008)
10.1021/nn500152u
Neuropilin-1-targeted gold nanoparticles enhance therapeutic efficacy of platinum(IV) drug for prostate cancer treatment.
A. Kumar (2014)
10.1002/CHIN.201227263
Silica‐Based Nanoprobes for Biomedical Imaging and Theranostic Applications
Juan L Vivero-Escoto (2012)
10.1166/JNN.2015.9761
Multifunctional Drug Delivery Systems Using Inorganic Nanomaterials: A Review.
Reshma Sao (2015)
10.1016/j.msec.2015.11.067
Polymeric nanoparticles for targeted drug delivery system for cancer therapy.
F. Masood (2016)
10.1186/s13167-015-0045-z
Bioabsorbable polymers in cancer therapy: latest developments
A. C. Fonseca (2015)
10.1039/c5nr07773g
Doxorubicin loaded dual pH- and thermo-responsive magnetic nanocarrier for combined magnetic hyperthermia and targeted controlled drug delivery applications.
Aziliz Hervault (2016)
10.1016/j.biomaterials.2013.03.061
Inhalable magnetic nanoparticles for targeted hyperthermia in lung cancer therapy.
Tanmoy Sadhukha (2013)
10.1016/j.jconrel.2015.12.006
Tumor-specific pH-responsive peptide-modified pH-sensitive liposomes containing doxorubicin for enhancing glioma targeting and anti-tumor activity.
Y. Zhao (2016)
10.7150/thno.11544
Magnetic Nanoparticles in Cancer Theranostics
O. Gobbo (2015)
10.1016/j.actbio.2015.10.017
Preferential tumor accumulation and desirable interstitial penetration of poly(lactic-co-glycolic acid) nanoparticles with dual coating of chitosan oligosaccharide and polyethylene glycol-poly(D,L-lactic acid).
G. Wang (2016)
10.2174/1381612821666150531170832
Graphene Oxide-Based Nanocarriers for Cancer Imaging and Drug Delivery.
Peihong You (2015)
10.1016/0166-6622(92)80221-M
Phase and dispersion stability effects in the synthesis of silica nanoparticles in a non-ionic reverse microemulsion
F. Arriagada (1992)
10.1021/acsnano.5b07846
ZnO-Based Nanoplatforms for Labeling and Treatment of Mouse Tumors without Detectable Toxic Side Effects.
Daixin Ye (2016)
10.3322/caac.21332
Cancer statistics, 2016
R. Siegel (2016)
10.1016/j.drudis.2008.09.005
The targeted delivery of cancer drugs across the blood-brain barrier: chemical modifications of drugs or drug-nanoparticles?
L. Juillerat-Jeanneret (2008)
10.1166/JNN.2008.301
Nanoparticle fluorescence based technology for biological applications.
W. Chen (2008)
10.1021/acsnano.5b07706
Intracellularly Acid-Switchable Multifunctional Micelles for Combinational Photo/Chemotherapy of the Drug-Resistant Tumor.
Tingting Wang (2016)
10.1002/ADFM.201404629
Cationic Polymer Modified Mesoporous Silica Nanoparticles for Targeted SiRNA Delivery to HER2+ Breast Cancer.
Worapol Ngamcherdtrakul (2015)
10.1016/J.SNB.2013.12.008
Laser synthesis and tailor-design of nanosized gold onto carbon nanotubes for non-enzymatic electrochemical glucose sensor
M. Gougis (2014)
10.1002/ANIE.200602866
Magnetic nanoparticles: synthesis, protection, functionalization, and application.
A. Lu (2007)
10.1158/0008-5472.CAN-08-1468
Drug delivery with carbon nanotubes for in vivo cancer treatment.
Zhuang Liu (2008)
10.1186/1556-276X-9-264
RGD-conjugated silica-coated gold nanorods on the surface of carbon nanotubes for targeted photoacoustic imaging of gastric cancer
C. Wang (2014)
10.1016/j.biomaterials.2013.08.058
Cholesteryl hyaluronic acid-coated, reduced graphene oxide nanosheets for anti-cancer drug delivery.
W. Miao (2013)
10.18632/oncotarget.7230
Association of rituximab with graphene oxide confers direct cytotoxicity for CD20-positive lymphoma cells
Chengke Luo (2016)
10.2147/IJN.S95440
Improving cytotoxicity against cancer cells by chemo-photodynamic combined modalities using silver-graphene quantum dots nanocomposites
K. Habiba (2016)
10.1002/PI.4822
Preparation of polymeric nanoparticles by novel electrospray nanoprecipitation
C. J. Luo (2015)
10.1021/JP9917648
Spectral Properties and Relaxation Dynamics of Surface Plasmon Electronic Oscillations in Gold and Silver Nanodots and Nanorods
Stephan Link‡ and (1999)
10.1016/j.nano.2015.11.012
Targeted nanosystems: Advances in targeted dendrimers for cancer therapy.
H. Yang (2016)
10.1016/j.biomaterials.2011.12.035
Multifunctional QD-based co-delivery of siRNA and doxorubicin to HeLa cells for reversal of multidrug resistance and real-time tracking.
Jinming Li (2012)
10.1016/j.jconrel.2016.01.053
Combination of drug-conjugated SWCNT nanocarriers for efficient therapy of cancer stem cells in a breast cancer animal model.
A. Al Faraj (2016)
10.1002/smll.201503121
Hollow Mesoporous Silica Nanocarriers with Multifunctional Capping Agents for In Vivo Cancer Imaging and Therapy.
S. Yang (2016)
10.2147/IJN.S4241
Nanoparticles and cancer therapy: A concise review with emphasis on dendrimers
D. Bharali (2009)
10.1038/354056a0
Helical microtubules of graphitic carbon
S. Iijima (1991)
10.1002/chem.201502177
Near-Infrared Light and pH-Responsive Polypyrrole@Polyacrylic acid/Fluorescent Mesoporous Silica Nanoparticles for Imaging and Chemo-Photothermal Cancer Therapy.
Manjie Zhang (2015)
10.7150/thno.14556
Cisplatin Prodrug-Conjugated Gold Nanocluster for Fluorescence Imaging and Targeted Therapy of the Breast Cancer
Fangyuan Zhou (2016)
10.2147/IJN.S46177
Multifunctional dendrimer-based nanoparticles for in vivo MR/CT dual-modal molecular imaging of breast cancer
Kangan Li (2013)
10.1016/j.jconrel.2016.03.008
Sequential co-delivery of miR-21 inhibitor followed by burst release doxorubicin using NIR-responsive hollow gold nanoparticle to enhance anticancer efficacy.
Y. Ren (2016)
10.1021/nn3044066
Codelivery of an optimal drug/siRNA combination using mesoporous silica nanoparticles to overcome drug resistance in breast cancer in vitro and in vivo.
Huan Meng (2013)
10.1002/adma.200801478
Polymeric Materials for Gene Delivery and DNA Vaccination.
David N. Nguyen (2009)
10.2174/0929867311320170006
Potential use of polymeric nanoparticles for drug delivery across the blood-brain barrier.
G. Tosi (2013)
10.1016/S0169-409X(00)00124-1
Block copolymer micelles for drug delivery: design, characterization and biological significance.
K. Kataoka (2001)
10.1016/0169-409X(95)00023-Z
Chemistry of polyethylene glycol conjugates with biologically active molecules
S. Zalipsky (1995)
10.1038/sj.clpt.6100400
Nanoparticles in Medicine: Therapeutic Applications and Developments
L. Zhang (2008)
10.1021/nn507485j
Hybrid Mesoporous Silica-Based Drug Carrier Nanostructures with Improved Degradability by Hydroxyapatite.
Xiaohong Hao (2015)
10.1021/acsnano.5b07473
Size-Tuning Ionization To Optimize Gold Nanoparticles for Simultaneous Enhanced CT Imaging and Radiotherapy.
Yan Dou (2016)
10.1016/j.drudis.2015.11.011
Interactions between carbon nanotubes and bioactives: a drug delivery perspective.
N. Mehra (2016)
10.1016/j.bios.2016.02.018
Pegylated folate and peptide-decorated graphene oxide nanovehicle for in vivo targeted delivery of anticancer drugs and therapeutic self-monitoring.
Jiangwei Tian (2016)
10.1038/nnano.2009.193
Plasmonic fluorescent quantum dots.
Yongdong Jin (2009)
10.1517/13543776.2013.761207
Dendrimer and cancer: a patent review (2006 – present)
X. Cai (2013)
10.1016/j.biomaterials.2013.11.088
Hydrophobic penetrating peptide PFVYLI-modified stealth liposomes for doxorubicin delivery in breast cancer therapy.
Defu Cai (2014)
10.1002/CHIN.200952249
Graphene: The New Two‐Dimensional Nanomaterial
C. Rao (2009)
10.1016/j.jconrel.2012.06.019
Size-controlled, dual-ligand modified liposomes that target the tumor vasculature show promise for use in drug-resistant cancer therapy.
K. Takara (2012)
10.2147/IJN.S91864
Fluorescent graphene quantum dots as traceable, pH-sensitive drug delivery systems
Jichuan Qiu (2015)
10.1088/0957-4484/24/37/375104
Targeting single-walled carbon nanotubes for the treatment of breast cancer using photothermal therapy.
L. F. Neves (2013)
10.1021/nn800669n
Shedding light on tumors using nanoparticles.
J. Rao (2008)
10.1016/J.JMMM.2015.02.078
Doxorubicin loaded PEG-b-poly(4-vinylbenzylphosphonate) coated magnetic iron oxide nanoparticles for targeted drug delivery
Magdalena Hałupka-Bryl (2015)
10.1016/J.DRUP.2005.07.002
Anticancer therapeutics: "Addictive" targets, multi-targeted drugs, new drug combinations.
H. Broxterman (2005)
10.1021/nl803798y
Colloidal suspensions of highly reduced graphene oxide in a wide variety of organic solvents.
S. Park (2009)
10.1016/j.jconrel.2015.11.017
pH-responsive hybrid quantum dots for targeting hypoxic tumor siRNA delivery.
H. Zhu (2015)
10.1016/j.ejps.2015.12.031
Recent advances in polymeric micelles for anti-cancer drug delivery.
Swati Biswas (2016)
Multifunctional all-in-one drug delivery systems for tumor targeting and sequential release of three different anti-tumor drugsOriginal
张永生 (2016)
10.1166/JNN.2008.274
New aspects of nanopharmaceutical delivery systems.
P. D. Marcato (2008)
10.2174/1568026615666150414145323
Metal based frameworks for drug delivery systems.
R. Popescu (2015)
10.1166/JNN.2014.9526
Recent advances in gold and silver nanoparticles: synthesis and applications.
Amin F. Majdalawieh (2014)
10.1016/j.bbrc.2015.08.022
Magnetic nanoparticle-based drug delivery for cancer therapy.
R. Tietze (2015)
10.1002/wnan.1242
Polymer nanoparticles for drug and small silencing RNA delivery to treat cancers of different phenotypes.
Rammohan Devulapally (2014)
10.1016/j.biomaterials.2014.03.046
pH-responsive polymer-liposomes for intracellular drug delivery and tumor extracellular matrix switched-on targeted cancer therapy.
Yi-Ting Chiang (2014)
10.1016/S0939-6411(99)00039-9
Polymeric micelles - a new generation of colloidal drug carriers.
M. Jones (1999)
10.1016/J.POLYMER.2007.10.021
Poly(amidoamine), polypropylenimine, and related dendrimers and dendrons possessing different 1 → 2 branching motifs : An overview of the divergent procedures
G. Newkome (2008)
10.1517/14712598.7.5.587
Programmed drug delivery: nanosystems for tumor targeting
E. Wagner (2007)
10.7150/thno.18607
Dual-pH Sensitive Charge-reversal Nanocomplex for Tumor-targeted Drug Delivery with Enhanced Anticancer Activity
Qing Zhou (2017)
10.1016/j.drudis.2011.09.015
Liposomal drug formulations in cancer therapy: 15 years along the road.
M. Slingerland (2012)
10.1021/nn901877h
A drug-loaded aptamer-gold nanoparticle bioconjugate for combined CT imaging and therapy of prostate cancer.
Dong-kyu Kim (2010)
10.1562/2005-05-11-IR-525
Quantum Dot-based Energy Transfer: Perspectives and Potential for Applications in Photodynamic Therapy
A. C. Samia (2006)
10.1038/nm1467
Artificially engineered magnetic nanoparticles for ultra-sensitive molecular imaging
Jaehyun Lee (2007)
10.1016/j.jconrel.2015.06.024
Enhancing cancer targeting and anticancer activity by a stimulus-sensitive multifunctional polymer-drug conjugate.
Y. Tu (2015)
10.1016/j.colsurfb.2015.12.026
Fabrication of doxorubicin nanoparticles by controlled antisolvent precipitation for enhanced intracellular delivery.
Y. T. Tam (2016)
10.1016/j.biomaterials.2013.11.022
Hypoxia-responsive polymeric nanoparticles for tumor-targeted drug delivery.
T. Thambi (2014)
10.1021/nn900947a
Simultaneous enhancement of photothermal stability and gene delivery efficacy of gold nanorods using polyelectrolytes.
Huang-Chiao Huang (2009)
Cancer therapies vivo MR / CT dual - modal molecular imaging of breast cancer
X Shi
10.1126/SCIENCE.1102896
Electric Field Effect in Atomically Thin Carbon Films
K. Novoselov (2004)
10.1002/ADMA.201290077
Multimodal Imaging Guided Photothermal Therapy using Functionalized Graphene Nanosheets Anchored with Magnetic Nanoparticles (Adv. Mater. 14/2012)
K. Yang (2012)
10.1016/j.biomaterials.2015.10.053
Rational design of multifunctional magnetic mesoporous silica nanoparticle for tumor-targeted magnetic resonance imaging and precise therapy.
W. Chen (2016)
10.1002/smll.201100669
Mitochondria-targeting single-walled carbon nanotubes for cancer photothermal therapy.
Feifan Zhou (2011)
10.1016/j.biomaterials.2015.08.032
Terminal modification of polymeric micelles with π-conjugated moieties for efficient anticancer drug delivery.
Yan Liang (2015)
10.1016/j.colsurfb.2015.04.003
Construction and evaluation of PAMAM-DOX conjugates with superior tumor recognition and intracellular acid-triggered drug release properties.
Lifang Cheng (2015)
10.1021/ac7018365
Flow cytometric analysis to detect pathogens in bacterial cell mixtures using semiconductor quantum dots.
Megan A. Hahn (2008)
10.1021/NN1001112
Erratum: Simultaneous enhancement of photothermal stability and gene delivery efficacy of gold nanorods using polyelectrolytes (ACS Nano (2009) 3 (2941-2952))
Huang-Chiao Huang (2010)
10.18632/oncotarget.8553
Engineered nanoparticles induce cell apoptosis: potential for cancer therapy
Dandan Ma (2016)
10.1016/j.actbio.2016.02.002
Peptide-functionalized ZCIS QDs as fluorescent nanoprobe for targeted HER2-positive breast cancer cells imaging.
M. Michalska (2016)
10.1016/S0513-5117(09)79159-8
Specific Targeting of Brain Tumors with an Optical/Magnetic Resonance Imaging Nanoprobe across the Blood-Brain Barrier
G. Rao (2010)
10.1002/smll.201503352
Synthesis and Characterization of Mn:ZnSe/ZnS/ZnMnS Sandwiched QDs for Multimodal Imaging and Theranostic Applications.
Yucheng Wang (2016)
10.1016/j.jconrel.2011.10.028
Photothermal-chemotherapy with doxorubicin-loaded hollow gold nanospheres: A platform for near-infrared light-trigged drug release.
Jian You (2012)
10.1088/0957-4484/20/37/375101
Gold nanoparticle sensitize radiotherapy of prostate cancer cells by regulation of the cell cycle.
W. Roa (2009)
10.1016/j.biomaterials.2014.03.038
Prostate stem cell antigen antibody-conjugated multiwalled carbon nanotubes for targeted ultrasound imaging and drug delivery.
H. Wu (2014)
10.2147/IJN.S78547
Preparation of poly(β-L-malic acid)-based charge-conversional nanoconjugates for tumor-specific uptake and cellular delivery
Qing Zhou (2015)
Multifunctional dendrimer-based nanoparticles for in 492 Q. Zhou et al.: Cancer therapies vivo MR/CT dual-modal molecular imaging of breast cancer
KA Li (2013)
10.1002/mabi.201300402
Co-delivery of oxaliplatin and demethylcantharidin via a polymer-drug conjugate.
Enhui Wang (2014)
10.2217/nnm.12.9
Tapping the potential of quantum dots for personalized oncology: current status and future perspectives.
C. Chen (2012)
10.3322/caac.21332
Cancer statistics, 2016
Rebecca L. Siegel Mph (2016)
10.1016/j.addr.2013.08.005
Carbon nanotubes for delivery of small molecule drugs.
B. Wong (2013)
10.1016/j.jconrel.2015.07.017
Targeted diagnostic magnetic nanoparticles for medical imaging of pancreatic cancer.
I. Rosenberger (2015)
Acid production in glycolysis-impaired tumors provides new insights into tumor metabolism.
G. Helmlinger (2002)
10.1016/j.biomaterials.2011.03.077
Gadolinium-loaded polymeric nanoparticles modified with Anti-VEGF as multifunctional MRI contrast agents for the diagnosis of liver cancer.
Y. Liu (2011)
10.1677/ERC.1.01045
Polymer-drug conjugates: towards a novel approach for the treatment of endrocine-related cancer.
R. Duncan (2005)
10.3109/08982104.2010.517537
A new method for liposome preparation using a membrane contactor
C. Jaafar-Maalej (2011)
10.1039/c3nr04448c
Multifunctional gold coated thermo-sensitive liposomes for multimodal imaging and photo-thermal therapy of breast cancer cells.
A. K. Rengan (2014)
10.2147/IJN.S26766
Clinical development of liposome-based drugs: formulation, characterization, and therapeutic efficacy
Hsin-I Chang (2012)
10.1021/acsnano.5b07249
Duality of Iron Oxide Nanoparticles in Cancer Therapy: Amplification of Heating Efficiency by Magnetic Hyperthermia and Photothermal Bimodal Treatment.
A. Espinosa (2016)
10.1016/J.MICROMESO.2015.06.012
Mesoporous silica nanoparticles capped with fluorescence-conjugated cyclodextrin for pH-activated controlled drug delivery and imaging
X. Chen (2015)
10.1039/c5nr05620a
In vivo cancer targeting and fluorescence-CT dual-mode imaging with nanoprobes based on silver sulfide quantum dots and iodinated oil.
Meng-Yao Qin (2015)
10.1016/j.addr.2015.09.009
Development of mesoporous silica-based nanoparticles with controlled release capability for cancer therapy.
Harutaka Mekaru (2015)
10.1126/SCIENCE.281.5385.2016
Quantum dot bioconjugates for ultrasensitive nonisotopic detection.
W. C. Chan (1998)
10.1016/j.addr.2008.03.003
Liposomes in ultrasonic drug and gene delivery.
Shao-ling Huang (2008)
10.1016/j.biotechadv.2016.02.001
The use of magnetic nanoparticles in cancer theranostics: Toward handheld diagnostic devices.
L. Hajba (2016)
10.1016/j.nano.2014.05.008
Targeted delivery of Dicer-substrate siRNAs using a dual targeting peptide decorated dendrimer delivery system.
Xiaoxuan Liu (2014)
10.3109/21691401.2016.1161641
GO-PEG as a drug nanocarrier and its antiproliferative effect on human cervical cancer cell line
Maryam Bikhof Torbati (2017)
10.1039/c5nr05585g
Radionuclide (131)I-labeled multifunctional dendrimers for targeted SPECT imaging and radiotherapy of tumors.
Jingyi Zhu (2015)
10.1016/j.drudis.2010.08.006
Cancer nanotechnology: application of nanotechnology in cancer therapy.
R. Misra (2010)
10.1016/j.colsurfb.2015.07.042
Liposomes loaded with hydrophilic magnetite nanoparticles: Preparation and application as contrast agents for magnetic resonance imaging.
S. German (2015)
10.2217/17435889.2.6.789
Characterization of nanoparticles for therapeutics.
J. B. Hall (2007)
10.1016/j.jconrel.2015.11.004
Lipid-dendrimer hybrid nanosystem as a novel delivery system for paclitaxel to treat ovarian cancer.
Yuanjie Liu (2015)
10.1007/S12274-008-8018-3
Bioconjugated silica nanoparticles: Development and applications
L. Wang (2008)
10.1038/nrc1566
Cancer nanotechnology: opportunities and challenges
M. Ferrari (2005)
10.1016/j.nano.2016.10.005
A drug-delivery strategy for overcoming drug resistance in breast cancer through targeting of oncofetal fibronectin.
Phei Er Saw (2017)
10.2217/nnm.14.130
Applications of dendrimers for brain delivery and cancer therapy.
Sukrut Somani (2014)
10.2174/092986710789957742
A review on biomedical applications of single-walled carbon nanotubes.
F. Liang (2010)
10.1016/j.biomaterials.2008.09.056
Single-step surface functionalization of polymeric nanoparticles for targeted drug delivery.
Y. Patil (2009)
10.1038/NMAT1849
The rise of graphene.
Andre K. Geim (2007)
10.1088/0957-4484/26/5/055102
Chlorin e6-ZnSe/ZnS quantum dots based system as reagent for photodynamic therapy.
I. V. Martynenko (2015)
10.1039/c5nr06756a
Bioresponsive carbon nano-gated multifunctional mesoporous silica for cancer theranostics.
Rajendra Prasad (2016)
Synthesis and characterization of monodispersed CdSe nanocrystals at lower temperature. Colloids Surf
R He (2006)
10.1016/j.jcis.2008.09.080
Synthesis and pH-dependent micellization of diblock copolymer mixtures.
K. Van Butsele (2009)
10.1002/anie.201101783
Multifunctional nanoparticles for targeted chemophotothermal treatment of cancer cells.
S. Lee (2011)
10.2217/nnm.15.182
Specific targeting and noninvasive imaging of breast cancer stem cells using single-walled carbon nanotubes as novel multimodality nanoprobes.
A. Al Faraj (2016)
10.1126/science.1160809
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
M. V. Vander Heiden (2009)
10.1016/j.jconrel.2015.10.017
cRGD-installed polymeric micelles loading platinum anticancer drugs enable cooperative treatment against lymph node metastasis.
J. Makino (2015)
10.1039/c5nr05067g
The synergistic effect of folate and RGD dual ligand of nanographene oxide on tumor targeting and photothermal therapy in vivo.
C. Jang (2015)
10.1002/mabi.201300288
HPMA copolymer conjugates of DOX and mitomycin C for combination therapy: physicochemical characterization, cytotoxic effects, combination index analysis, and anti-tumor efficacy.
Hana Kostková (2013)
10.1002/anie.200804135
Polymeric core-shell assemblies mediated by host-guest interactions: versatile nanocarriers for drug delivery.
J. Zhang (2009)
10.1021/acs.chemmater.6b00208
Highly Fluorescent Ribonuclease-A-Encapsulated Lead Sulfide Quantum Dots for Ultrasensitive Fluorescence in Vivo Imaging in the Second Near-Infrared Window
Yifei Kong (2016)
10.1002/CHIN.201103264
Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives.
K. Knop (2011)
10.1016/j.actbio.2015.11.036
Mesoporous manganese silicate coated silica nanoparticles as multi-stimuli-responsive T1-MRI contrast agents and drug delivery carriers.
X. Li (2016)
10.1039/c5nr07785k
A graphene oxide based smart drug delivery system for tumor mitochondria-targeting photodynamic therapy.
Yanchun Wei (2016)
10.7150/thno.10657
Off to the Organelles - Killing Cancer Cells with Targeted Gold Nanoparticles
M. Kodiha (2015)
10.1002/adma.200702051
Graphene Physics in Graphite
Y. Kopelevich (2007)
10.1002/adma.201001068
Graphene and graphene oxide: synthesis, properties, and applications.
Yanwu Zhu (2010)
10.1016/j.ijpharm.2015.04.028
Folate-decorated anticancer drug and magnetic nanoparticles encapsulated polymeric carrier for liver cancer therapeutics.
Y. Li (2015)
10.1039/c0nr00096e
Silica-based nanoparticles for photodynamic therapy applications.
P. Couleaud (2010)
10.1016/j.biomaterials.2011.01.001
Computed tomography imaging of cancer cells using acetylated dendrimer-entrapped gold nanoparticles.
Huaiwen Wang (2011)
10.1016/J.NANTOD.2010.03.003
Targeted Nanodelivery of Drugs and Diagnostics.
M. Phillips (2010)
10.2147/IJN.S90198
Folic acid targeted Mn:ZnS quantum dots for theranostic applications of cancer cell imaging and therapy
I. Bwatanglang (2016)
10.7150/thno.11918
Triple-Modal Imaging of Magnetically-Targeted Nanocapsules in Solid Tumours In Vivo
J. Bai (2016)
10.1039/c2cp40225d
The electrochemistry of CVD graphene: progress and prospects.
D. Brownson (2012)
10.1021/acsami.5b02803
Multifunctional Poly(L-lactide)-Polyethylene Glycol-Grafted Graphene Quantum Dots for Intracellular MicroRNA Imaging and Combined Specific-Gene-Targeting Agents Delivery for Improved Therapeutics.
H. Dong (2015)
10.1208/aapsj0902015
Targeted pharmaceutical nanocarriers for cancer therapy and imaging
V. Torchilin (2008)
10.1016/j.jconrel.2014.05.037
Non-viral nanocarriers for siRNA delivery in breast cancer.
J. Zhang (2014)
10.1039/c0pp00380h
Quantum dot-folic acid conjugates as potential photosensitizers in photodynamic therapy of cancer.
Vincent Morosini (2011)
10.1039/c3dt51368h
Seed-mediated growth of jack-shaped gold nanoparticles from cyclodextrin-coated gold nanospheres.
A. Sanchez (2013)
10.1016/j.nano.2015.05.010
Application of gold nanoparticles for gastrointestinal cancer theranostics: A systematic review.
Mohan Singh (2015)
10.1016/0021-9797(68)90272-5
Controlled growth of monodisperse silica spheres in the micron size range
W. Stoeber (1968)
10.1016/j.actbio.2016.02.011
MRI-guided liposomes for targeted tandem chemotherapy and therapeutic response prediction.
Lili Ren (2016)
10.1016/j.jconrel.2013.07.011
Targeting HER2+ breast cancer cells: lysosomal accumulation of anti-HER2 antibodies is influenced by antibody binding site and conjugation to polymeric nanoparticles.
S. Owen (2013)
10.1016/j.jcis.2015.12.052
Highly efficient nuclear delivery of anti-cancer drugs using a bio-functionalized reduced graphene oxide.
X. Zheng (2016)
10.1002/CHIN.200215252
Convergent Dendrons and Dendrimers: From Synthesis to Applications
S. Grayson (2002)
10.1016/j.jconrel.2016.03.009
Doxorubicin/gold-loaded core/shell nanoparticles for combination therapy to treat cancer through the enhanced tumor targeting.
K. Kim (2016)
10.1021/nn500212h
Highly sensitive single domain antibody-quantum dot conjugates for detection of HER2 biomarker in lung and breast cancer cells.
Tatsiana Rakovich (2014)
10.1021/ja900025f
Photoinduced intracellular controlled release drug delivery in human cells by gold-capped mesoporous silica nanosphere.
Juan L Vivero-Escoto (2009)
10.1002/lsm.20968
Single‐wall carbon nanotubes assisted photothermal cancer therapy: Animal study with a murine model of squamous cell carcinoma
Naiyan Huang (2010)
10.1016/j.actbio.2016.01.039
Self-assembled gemcitabine-gadolinium nanoparticles for magnetic resonance imaging and cancer therapy.
L. Li (2016)
10.1016/j.addr.2007.11.009
Polymer-drug conjugates: recent development in clinical oncology.
Chun Xing Li (2008)
10.1016/j.biomaterials.2015.11.041
Hybrid graphene/Au activatable theranostic agent for multimodalities imaging guided enhanced photothermal therapy.
S. Gao (2016)
10.1016/j.addr.2009.05.006
Combination therapy: opportunities and challenges for polymer-drug conjugates as anticancer nanomedicines.
F. Greco (2009)
10.1021/ar200044b
Surface-engineered magnetic nanoparticle platforms for cancer imaging and therapy.
Jin Xie (2011)
10.1016/J.COLSURFA.2005.07.017
Synthesis and characterization of mondispersed CdSe nanocrystals at lower temperature
R. He (2006)
10.1021/JA051833Y
Surface modulation of magnetic nanocrystals in the development of highly efficient magnetic resonance probes for intracellular labeling.
Ho-Taek Song (2005)
10.1016/j.drudis.2013.10.005
Magnetic nanoparticles: a novel platform for cancer theranostics.
A. Singh (2014)
10.1021/acs.molpharmaceut.5b00866
Predictable Heating and Positive MRI Contrast from a Mesoporous Silica-Coated Iron Oxide Nanoparticle.
Katie R. Hurley (2016)
10.1021/acsami.5b08087
Manganese Oxide-Coated Carbon Nanotubes As Dual-Modality Lymph Mapping Agents for Photothermal Therapy of Tumor Metastasis.
S. Wang (2016)
10.1117/1.3078803
Cancer photothermal therapy in the near-infrared region by using single-walled carbon nanotubes.
Feifan Zhou (2009)
10.1021/cr068445e
Magnetic iron oxide nanoparticles: synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications.
S. Laurent (2008)
10.1038/nrc1958
Polymer conjugates as anticancer nanomedicines
R. Duncan (2006)
10.1016/j.biomaterials.2011.07.071
Synergistic effect of chemo-photothermal therapy using PEGylated graphene oxide.
W. Zhang (2011)
10.1016/S0169-409X(96)00401-2
Polymeric micelles as new drug carriers
G. Kwon (1996)
10.1016/j.biomaterials.2012.08.072
pH-sensitive poly(histidine)-PEG/DSPE-PEG co-polymer micelles for cytosolic drug delivery.
H. Wu (2013)
10.1021/acsnano.5b07781
Irinotecan Delivery by Lipid-Coated Mesoporous Silica Nanoparticles Shows Improved Efficacy and Safety over Liposomes for Pancreatic Cancer.
X. Liu (2016)
10.1166/JNN.2015.10614
Carbon Nanomaterials for Drug Delivery and Cancer Therapy.
Mrinmay Chakrabarti (2015)
10.1021/acsami.5b07510
Noncovalent Ruthenium(II) Complexes-Single-Walled Carbon Nanotube Composites for Bimodal Photothermal and Photodynamic Therapy with Near-Infrared Irradiation.
Pingyu Zhang (2015)
10.1021/nl8016253
Iodide ions control seed-mediated growth of anisotropic gold nanoparticles.
Jill E Millstone (2008)
10.1038/nrd2614
Nanoparticle therapeutics: an emerging treatment modality for cancer
M. Davis (2008)
10.1016/j.nano.2008.06.002
Emerging nanopharmaceuticals.
Willie E. Bawarski (2008)
10.7150/thno.5860
Superparamagnetic Nanoparticle Clusters for Cancer Theranostics Combining Magnetic Resonance Imaging and Hyperthermia Treatment
K. Hayashi (2013)
10.1021/bc5005137
Functionalized graphene oxide nanoparticles for cancer cell-specific delivery of antitumor drug.
Xubo Zhao (2015)
10.1039/c5nr08753h
Cellulose conjugated FITC-labelled mesoporous silica nanoparticles: intracellular accumulation and stimuli responsive doxorubicin release.
Abdul Hakeem (2016)
10.1021/acsnano.5b04378
Polymer-Grafted Mesoporous Silica Nanoparticles as Ultrasound-Responsive Drug Carriers.
J. Paris (2015)
10.1039/c3nr33560g
A review of fabrication and applications of carbon nanotube film-based flexible electronics.
S. Park (2013)
10.1166/JNN.2014.8900
Biological applications of gold nanoparticles.
Monic Shah (2014)
10.1016/j.biomaterials.2010.08.096
Optimization of surface chemistry on single-walled carbon nanotubes for in vivo photothermal ablation of tumors.
X. Liu (2011)
10.1016/J.JCONREL.2006.06.010
In vitro and in vivo intracellular liposomal delivery of antisense oligonucleotides and anticancer drug.
R. I. Pakunlu (2006)
10.1016/j.biomaterials.2009.07.025
Targeted delivery and controlled release of doxorubicin to cancer cells using modified single wall carbon nanotubes.
X. Zhang (2009)
10.1016/j.biomaterials.2016.01.008
Hollow mesoporous silica nanoparticles facilitated drug delivery via cascade pH stimuli in tumor microenvironment for tumor therapy.
J. Liu (2016)
10.1021/acsami.5b10426
Development of a Graphene Oxide Nanocarrier for Dual-Drug Chemo-phototherapy to Overcome Drug Resistance in Cancer.
T. H. Tran (2015)



This paper is referenced by
10.1002/9781119468455.ch67
Supramolecular Graphene‐Based Systems for Drug Delivery
S. M. Cruz (2019)
Engineering and Study of Biocompatible Nanoceramics
K. Bogusz (2018)
10.3390/nano10091696
Nanotreatment and Nanodiagnosis of Prostate Cancer: Recent Updates
Mahmood Barani (2020)
Nanotechnology in medicine: innovation to market
Bajwa Sz (2017)
10.2147/IJN.S158696
Stimuli-responsive polymeric micelles for drug delivery and cancer therapy
Qing Zhou (2018)
10.1016/j.heliyon.2019.e03124
Effects of PEGylated Fe–Fe3O4 core-shell nanoparticles on NIH3T3 and A549 cell lines
B.H. Domac (2020)
10.1515/ntrev-2018-0013
Nanoimmunotherapy – cloaked defenders to breach the cancer fortress
Gayathri Kandasamy (2018)
10.2174/1573413714666180426112851
Nanotechnology Derived Nanotools in Biomedical Perspectives: An Update
Akshay Patil (2018)
10.3390/ijms21145174
Synthesis, Properties, and Biological Applications of Metallic Alloy Nanoparticles
Kim-Hung Huynh (2020)
A Review on Stimuli-Responsive Polymers and Recent Strategies for Treating Cancer Based on Stimuli Responsive Nanocarriers
(2020)
10.1080/21691401.2018.1523182
Biofunctionalized MnFe2O4@Au core–shell nanoparticles for pH-responsive drug delivery and hyperthermal agent for cancer therapy
R. M. (2018)
10.1002/adtp.201900136
Organic Nanocarriers for Delivery and Targeting of Therapeutic Agents for Cancer Treatment
Y. Peng (2020)
10.3390/molecules24193547
Nanobiomaterials Used in Cancer Therapy: An Up-To-Date Overview
I. Lungu (2019)
10.1515/ntrev-2019-0050
The effect of nano-SiO2 on concrete properties: a review
Chenglong Zhuang (2019)
10.1039/d0tb01682a
MMP-2 sensitive poly(malic acid) micelles stabilized by π-π stacking enable high drug loading capacity.
Youbei Qiao (2020)
10.1515/ntrev-2020-0079
Polymer nanocomposite sunlight spectrum down-converters made by open-air PLD
A. Darwish (2020)
10.1002/mabi.201800481
HPMA-Based Nanocarriers for Effective Immune System Stimulation.
S. Kramer (2019)
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