Online citations, reference lists, and bibliographies.
← Back to Search

Patient-centered Weight Tracking As An Early Cancer Detection Strategy

Jonathan J. Hue, S. Markt, Goutham Rao, J. Winter
Published 2020 · Medicine

Save to my Library
Download PDF
Analyze on Scholarcy Visualize in Litmaps
Share
Reduce the time it takes to create your bibliography by a factor of 10 by using the world’s favourite reference manager
Time to take this seriously.
Get Citationsy
Early detection is a valued strategy to decrease cancer mortality rates; however, new strategies are needed. Unintentional weight loss (UWL) is experienced by patients across the cancer spectrum, but often goes unnoticed. Patient-centered weight tracking may be a useful early detection marker. Fifty patients were enrolled in a prospective patient-centered weight tracking trial. Patients received a scale and monetary compensation to participate. A reminder to measure and record weight was texted to participants for 26 consecutive weeks. Most patients were black (86.0%) and female (68.0%). The median age was 47 years (range: 22-84 years). Many participants had Medicaid (42.0%) and the median household income by home zip code was $31,046. After 26 weeks, 90% of patients had recorded at least one weight. Among all patients, 73.7% of all possible weights were recorded and the median response rate per patient was 92.3% (24 of 26 weights). There was no difference in the response rates during the first and second halves of the study (77.7% vs. 69.7%, P = 0.53). The range of weight change over the study period was 16.1% loss to 25.0% gain, with 56% of patients maintaining stable weight. Seven patients (14.0%) lost more than 5% weight and 11 patients (22.0%) gained over 5%. Of the seven patients with weight loss, two (4.0% of the cohort) were determined to have UWL. Patient-centered weight tracking is feasible and inexpensive, and has potential as an early detector of UWL. Further studies are needed to apply this strategy to detect underlying malignancies.
This paper references
10.1016/S0149-2918(05)80001-3
Prognostic effect of weight loss prior tochemotherapy in cancer patients
W. Dewys (1980)
10.7326/0003-4819-95-5-568
Involuntary weight loss: diagnostic and prognostic significance.
K. Marton (1981)
10.1001/ARCHSURG.1985.01390320023003
Pancreatic cancer. Adjuvant combined radiation and chemotherapy following curative resection.
M. Kalser (1985)
10.1001/ARCHINTE.1986.00360130224029
Unintentional weight loss. A retrospective analysis of 154 cases.
M. Rabinovitz (1986)
10.1111/j.1532-5415.1991.tb02496.x
Unexplained Weight Loss in the Ambulatory Elderly
M. P. Thompson (1991)
10.1136/bmj.306.6880.752
Randomised comparison of combination chemotherapy plus supportive care with supportive care alone in patients with metastatic colorectal cancer.
W. Scheithauer (1993)
10.1046/j.1365-2796.2001.00771.x
Unintentional weight loss: diagnosis and prognosis. The first prospective follow‐up study from a secondary referral centre
P. Lankisch (2001)
10.1016/S0953-6205(02)00032-8
Assessing clinical probability of organic disease in patients with involuntary weight loss: a simple score.
J. Bilbao-Garay (2002)
10.1016/j.ejim.2007.09.019
Involuntary weight loss. Does a negative baseline evaluation provide adequate reassurance?
C. Metalidis (2008)
10.1097/MCO.0b013e328300ecc1
Cachexia: prevalence and impact in medicine
B. Tan (2008)
10.1245/s10434-009-0881-y
Long-Term Survival Results of Surgery Alone Versus Surgery Plus 5-Fluorouracil and Leucovorin for Stage II and Stage III Colon Cancer: Pooled Analysis of NSABP C-01 Through C-05. A Baseline from Which to Compare Modern Adjuvant Trials
N. Wilkinson (2009)
10.1200/JCO.2010.28.1386
Gemcitabine plus bevacizumab compared with gemcitabine plus placebo in patients with advanced pancreatic cancer: phase III trial of the Cancer and Leukemia Group B (CALGB 80303).
H. Kindler (2010)
10.1038/nature09515
Distant Metastasis Occurs Late during the Genetic Evolution of Pancreatic Cancer
S. Yachida (2010)
10.2337/dc10-0077
Finger-Stick Glucose Monitoring
L. Olansky (2010)
10.1016/S0167-4943(10)70008-X
Evaluating probability of cancer among older people with unexplained, unintentional weight loss.
Shih-Ping Chen (2010)
10.1056/NEJMoa1011923
FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer.
T. Conroy (2011)
10.1016/j.archger.2010.10.016
Evaluating diagnostic strategy of older patients with unexplained unintentional body weight loss: a hospital-based study.
Jiamei Wu (2011)
10.1136/bmj.d3621
Relative effectiveness of clinic and home blood pressure monitoring compared with ambulatory blood pressure monitoring in diagnosis of hypertension: systematic review
J. Hodgkinson (2011)
10.1016/j.mcna.2014.01.012
Involuntary weight loss.
Christopher J. Wong (2014)
10.1001/jamainternmed.2014.981
Consequences of false-positive screening mammograms.
A. Tosteson (2014)
10.1373/clinchem.2015.239863
Validation of new cancer biomarkers: a position statement from the European group on tumor markers.
M. Duffy (2015)
10.15420/ecr.2015.10.2.95
Home Blood Pressure Monitoring.
J. George (2015)
10.1200/JCO.2015.33.15_SUPPL.E20644
The incidence and impact of weight loss with cachexia in gastric cancer patients.
Hongli Li (2015)
10.14236/jhi.v22i3.137
Losing weights: failure to recognise and act on weight loss documented in an electronic health record
R. El-Kareh (2015)
10.7326/M15-2886
Screening for Breast Cancer: U.S. Preventive Services Task Force Recommendation Statement
A. Siu (2016)
10.1001/jama.2016.5989
Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement.
K. Bibbins-Domingo (2016)
10.1097/MPA.0000000000000590
Weight Loss, Diabetes, Fatigue, and Depression Preceding Pancreatic Cancer
S. Olson (2016)
10.1155/2017/6951495
The Effect of Adherence to Dietary Tracking on Weight Loss: Using HLM to Model Weight Loss over Time
John Spencer Ingels (2017)
10.1016/j.lungcan.2018.07.005
Prediagnosis weight loss, a stronger factor than BMI, to predict survival in patients with lung cancer.
H. Morel (2018)
10.1001/jama.2018.10897
Screening for Cervical Cancer: US Preventive Services Task Force Recommendation Statement
S. Curry (2018)
10.1007/s00520-018-4560-z
Pre-to-post diagnosis weight trajectories in colorectal cancer patients with non-metastatic disease
M. van Zutphen (2018)
10.1056/NEJMoa1809775
FOLFIRINOX or Gemcitabine as Adjuvant Therapy for Pancreatic Cancer
T. Conroy (2018)
10.1097/MD.0000000000017451
Factors associated with false negative and false positive results of prostate-specific antigen (PSA) and the impact on patient health
M. C. Bernal-Soriano (2019)
10.1056/NEJMp2003539
Virtually Perfect? Telemedicine for Covid-19.
J. Hollander (2020)
10.3322/caac.21590
Cancer statistics, 2020
R. Siegel (2020)



This paper is referenced by
Semantic Scholar Logo Some data provided by SemanticScholar