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Effect Of Hyperthermic Intrathoracic Chemotherapy On The Malignant Pleural Mesothelioma: A Systematic Review And Meta-analysis

Z. Zhao, S. Zhao, M. Ren, Z. Liu, Z. Li, L. Yang
Published 2017 · Medicine

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Surgery-based multimodality therapies have been used to control the malignant effusion and its recurrence in malignant pleural mesothelioma (MPM). Hyperthermic intrathoracic chemotherapy (HITHOC) has been used in the treatment of malignant pleural mesothelioma, but the results were controversial. The aim of the current study was, therefore, to conduct a systematic review and meta-analysis on the effect of HITHOC on MPM therapy. After thorough searching of online databases, total 21 articles were included into qualitative systematic review and 5 of them were used to conduct qualitative meta-analysis. It was found that most of HITHOC was used in combination of surgical resection including extrapleural pneumonectomy or pleurectomy/decortication. Patients who received HITHOC had significantly longer median survival length compared to the patients without HITHOC (Hedges’s g = 0.384 ± 0.105, 95% CI: 0.178∼0.591, P < 0.001). In addition, HITHOC as palliative therapy was favored (Hedges’s g = 0.591 ± 0.201, 95% CI: 0.196∼0.967, P < 0.001) in terms of recurrence free interval. The findings of the current study suggested that HITHOC is one of the safe and effective therapies in prolonging patients’ median survival time and extending recurrence free interval.
This paper references
10.1016/j.ejca.2013.09.024
Role of hyperthermic intraoperative peritoneal chemotherapy in the management of peritoneal metastases.
D. Elias (2014)
10.1016/J.LUNGCAN.2004.11.003
Surgical management of malignant pleural mesothelioma: a systematic review and evidence summary.
D. Maziak (2005)
10.1002/1097-0142(20011015)92:8<2197::AID-CNCR1563>3.0.CO;2-F
Hyperthermic pleural perfusion with cisplatin
A. Yellin (2001)
10.1007/s11748-015-0535-x
Interim results of pleurectomy/decortication and intraoperative intrapleural hyperthermic cisplatin perfusion for patients with malignant pleural mesothelioma intolerable to extrapleural pneumonectomy
H. Ishibashi (2015)
10.1038/sj.bjc.6601000
Long-term results of intrathoracic chemohyperthermia (ITCH) for the treatment of pleural malignancies
O. Monneuse (2003)
10.1080/02656730601012508
Hyperthermia combined with intra-thoracic chemotherapy and radiotherapy for malignant pleural mesothelioma
Hongqiang Xia (2006)
10.1016/j.jtcvs.2009.02.046
Extrapleural pneumonectomy followed by intracavitary intraoperative hyperthermic cisplatin with pharmacologic cytoprotection for treatment of malignant pleural mesothelioma: a phase II prospective study.
T. R. Tilleman (2009)
10.1016/j.ejso.2010.01.006
Pseudomyxoma peritonei: a French multicentric study of 301 patients treated with cytoreductive surgery and intraperitoneal chemotherapy.
D. Elias (2010)
10.1016/j.jtcvs.2012.12.037
Hyperthermic intraoperative pleural cisplatin chemotherapy extends interval to recurrence and survival among low-risk patients with malignant pleural mesothelioma undergoing surgical macroscopic complete resection.
D. Sugarbaker (2013)
10.1200/JCO.1994.12.6.1156
A phase II trial of pleurectomy/decortication followed by intrapleural and systemic chemotherapy for malignant pleural mesothelioma.
V. Rusch (1994)
10.1016/J.ATHORACSUR.2004.05.025
Intrapleural hyperthermic perfusion with chemotherapy increases apoptosis in malignant pleuritis.
Y. Matsuzaki (2004)
10.1186/1749-8090-9-125
Anaesthetic management of cytoreductive surgery followed by hyperthermic intrathoracic chemotherapy perfusion
C. Kerscher (2014)
10.1016/j.lungcan.2013.11.026
A systematic review and meta-analysis of surgical treatments for malignant pleural mesothelioma.
C. Cao (2014)
10.1016/J.THORSURG.2004.06.006
Patterns of failure following surgical resection for malignant pleural mesothelioma.
P. Jänne (2004)
10.18632/oncotarget.7622
Retrospective analysis on the safety of 5,759 times of bedside hyperthermic intra-peritoneal or intra-pleural chemotherapy (HIPEC)
L. Liu (2016)
10.1155/2012/471205
Pharmacokinetics of Hyperthermic Intrathoracic Chemotherapy following Pleurectomy and Decortication
P. Sugarbaker (2012)
10.1016/S0960-7404(99)00007-9
The treatment of malignancy by hyperthermia.
C. Christophi (1998)
10.1016/j.rmed.2013.01.010
Intrapleural hyperthermic perfusion chemotherapy in subjects with metastatic pleural malignancies.
A. Işık (2013)
10.1016/S0360-3016(01)02481-6
Radical pleurectomy/decortication and intraoperative radiotherapy followed by conformal radiation with or without chemotherapy for malignant pleural mesothelioma.
T. T. Lee (2002)
10.1245/s10434-008-9899-9
Surgical Treatment in the Management of Malignant Pleural Mesothelioma: A Single Institution’s Experience
J. Sandick (2008)
10.1378/CHEST.121.2.480
Cytoreductive surgery and intraoperative hyperthermic intrathoracic chemotherapy in patients with malignant pleural mesothelioma or pleural metastases of thymoma.
E. de Bree (2002)
Cytoreductive surgery and intraoperative hyperthermic intrathoracic chemotherapy in patients with malignant pleural mesothelioma or pleural metastases of thymoma. Chest
E de Bree (2002)
10.2217/fon.15.286
Pleurectomy/decortication and hyperthermic intrapleural chemotherapy for malignant pleural mesothelioma: initial experience.
M. Migliore (2015)
10.4251/wjgo.v2.i2.68
Hyperthermic intraperitoneal chemotherapy: Rationale and technique.
S. González-Moreno (2010)
10.1378/CHEST.99.1.54
Safety and efficacy of thrombolytic therapy for superior vena cava syndrome.
B. Gray (1991)
10.1245/ASO.2003.03.022
Cytoreductive Surgery Combined With Intraoperative Hyperthermic Intrathoracic Chemotherapy for Stage I Malignant Pleural Mesothelioma
S. van Ruth (2003)
10.1200/JCO.2005.04.6813
Phase I to II study of pleurectomy/decortication and intraoperative intracavitary hyperthermic cisplatin lavage for mesothelioma.
W. Richards (2006)
10.1097/JTO.0b013e3182288af9
Pleurectomy/Decortication, Hyperthermic Pleural Lavage with Povidone-Iodine Followed by Adjuvant Chemotherapy in Patients with Malignant Pleural Mesothelioma
L. Lang-Lazdunski (2011)
10.1002/SIM.1186
Quantifying heterogeneity in a meta-analysis.
J. Higgins (2002)
10.1093/ejcts/ezs418
Cytoreductive surgery and hyperthermic intrathoracic chemotherapy perfusion for malignant pleural tumours: perioperative management and clinical experience.
M. Ried (2013)
10.1002/jso.23321
Local and systemic exposure of cisplatin during hyperthermic intrathoracic chemotherapy perfusion after pleurectomy and decortication for treatment of pleural malignancies
M. Ried (2013)
10.1097/00001813-200301000-00008
Pharmacokinetics of doxorubicin and cisplatin used in intraoperative hyperthermic intrathoracic chemotherapy after cytoreductive surgery for malignant pleural mesothelioma and pleural thymoma
S. van Ruth (2003)
10.1097/JTO.0b013e31824ab6c5
Pleurectomy/Decortication is Superior to Extrapleural Pneumonectomy in the Multimodality Management of Patients with Malignant Pleural Mesothelioma
L. Lang-Lazdunski (2012)
10.1016/j.jtcvs.2014.10.041
Pleurectomy/decortication, hyperthermic pleural lavage with povidone-iodine, prophylactic radiotherapy, and systemic chemotherapy in patients with malignant pleural mesothelioma: a 10-year experience.
L. Lang-Lazdunski (2015)
10.2217/fon.14.256
Cytoreductive surgery and hyperthermic intrapleural chemotherapy for malignant pleural diseases: preliminary experience.
M. Migliore (2015)
10.1080/02656730701455318
Laboratory and clinical basis for hyperthermia as a component of intracavitary chemotherapy
P. Sugarbaker (2007)
10.1016/S1470-2045(11)70149-8
Extra-pleural pneumonectomy versus no extra-pleural pneumonectomy for patients with malignant pleural mesothelioma: clinical outcomes of the Mesothelioma and Radical Surgery (MARS) randomised feasibility study
T. Treasure (2011)
10.1093/ejcts/ezv039
Pleural recurrence of thymoma: surgical resection followed by hyperthermic intrathoracic perfusion chemotherapy†.
M. Ambrogi (2016)
10.1007/s00432-013-1526-x
Intrapleural hyperthermic perfusion using distilled water at 48 °C for malignant pleural effusion
Mingchen Ba (2013)



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