Online citations, reference lists, and bibliographies.
← Back to Search

Magnetic Hydroxyapatite: A Promising Multifunctional Platform For Nanomedicine Application

S. Mondal, P. Manivasagan, S. Bharathiraja, Madhappan Santha Moorthy, H. Kim, H. Seo, K. D. Lee, J. Oh
Published 2017 · Materials Science, Medicine

Cite This
Download PDF
Analyze on Scholarcy
Share
In this review, specific attention is paid to the development of nanostructured magnetic hydroxyapatite (MHAp) and its potential application in controlled drug/gene delivery, tissue engineering, magnetic hyperthermia treatment, and the development of contrast agents for magnetic resonance imaging. Both magnetite and hydroxyapatite materials have excellent prospects in nanomedicine with multifunctional therapeutic approaches. To date, many research articles have focused on biomedical applications of nanomaterials because of which it is very difficult to focus on any particular type of nanomaterial. This study is possibly the first effort to emphasize on the comprehensive assessment of MHAp nanostructures for biomedical applications supported with very recent experimental studies. From basic concepts to the real-life applications, the relevant characteristics of magnetic biomaterials are patented which are briefly discussed. The potential therapeutic and diagnostic ability of MHAp-nanostructured materials make them an ideal platform for future nanomedicine. We hope that this advanced review will provide a better understanding of MHAp and its important features to utilize it as a promising material for multifunctional biomedical applications.
This paper references
10.1007/s00604-015-1504-x
Multifunctional hydroxyapatite nanoparticles for drug delivery and multimodal molecular imaging
S. S. Syamchand (2015)
10.1007/s10856-008-3565-4
Bioactivity of gelatin coated magnetic iron oxide nanoparticles: in vitro evaluation
B. Gaihre (2009)
10.1016/j.actbio.2010.10.004
Increased osteoblast functions in the presence of hydroxyapatite-coated iron oxide nanoparticles.
N. Tran (2011)
10.1016/j.ab.2012.03.013
Application of magnetic hydroxyapatite nanoparticles for solid phase extraction of plasmid DNA.
Zhi Shan (2012)
10.1080/10667857.2016.1224609
Biomimetic nanostructured hydroxyapatite coatings on metallic implant materials
Sachin A. Mali (2016)
10.1002/smll.200700784
In vivo MRI detection of gliomas by chlorotoxin-conjugated superparamagnetic nanoprobes.
C. Sun (2008)
10.1039/c5nr07023f
Magnetic hydroxyapatite nanoworms for magnetic resonance diagnosis of acute hepatic injury.
Yun-Jun Xu (2016)
10.2147/IJN.S30320
Superparamagnetic iron oxide nanoparticles: magnetic nanoplatforms as drug carriers
Wahajuddin (2012)
Effect of Fe 3 O 4 , Fe and Cu doping on magnetic properties and behaviour in physiological solution of biological hydroxyapatite/glass composite
O Kuda (2009)
10.1016/j.aca.2015.04.044
Colorimetric detection of pathogenic bacteria using platinum-coated magnetic nanoparticle clusters and magnetophoretic chromatography.
Donghoon Kwon (2015)
10.1016/j.actbio.2009.09.017
A novel route in bone tissue engineering: magnetic biomimetic scaffolds.
N. Bock (2010)
10.1021/JP992088C
Novel Photocatalyst: Titania-Coated Magnetite. Activity and Photodissolution
Donia Beydoun and (2000)
10.1016/J.CAP.2015.04.032
Self-assembled magnetic lamellar hydroxyapatite as an efficient nano-vector for gene delivery
G. Xiong (2015)
10.1016/j.biomaterials.2009.04.020
The in vivo performance of biomagnetic hydroxyapatite nanoparticles in cancer hyperthermia therapy.
C. Hou (2009)
10.1179/174367613X13789812714425
Processing of natural resourced hydroxyapatite ceramics from fish scale
Sudip Mondal (2010)
10.1016/J.JMMM.2008.12.027
Magnetic properties of Co-ferrite-doped hydroxyapatite nanoparticles having a core/shell structure
N. Petchsang (2009)
10.1016/j.msec.2016.12.012
A biological method for in-situ synthesis of hydroxyapatite-coated magnetite nanoparticles using Enterobacter aerogenes: Characterization and acute toxicity assessments.
Elham Ahmadzadeh (2017)
10.1016/j.colsurfb.2012.10.067
Magnetic nanohydroxyapatite/PVA composite hydrogels for promoted osteoblast adhesion and proliferation.
R. Hou (2013)
10.1177/0885328216631670
Mechanistic contribution of electroconductive hydroxyapatite–titanium disilicide composite on the alignment and proliferation of cells
A. Kumar (2016)
10.1016/j.ijpharm.2008.08.020
Gelatin-coated magnetic iron oxide nanoparticles as carrier system: drug loading and in vitro drug release study.
B. Gaihre (2009)
10.1039/c6cp00474a
Hydroxyapatite substituted by transition metals: experiment and theory.
M. Zilm (2016)
10.1016/J.JMMM.2006.10.776
One-pot polyol synthesis of monosize PVP-coated sub-5 nm Fe3O4 nanoparticles for biomedical applications
H. Liu (2007)
10.1002/ADEM.201080094
Structure–Process–Property Relationship of Biomimetic Chitosan‐Based Nanocomposite Scaffolds for Tissue Engineering: Biological, Physico‐Chemical, and Mechanical Functions
N. Maganti (2011)
10.1590/S0001-37652009000200004
Preparation and characterization of hydroxyapatite-coated iron oxide particles by spray-drying technique.
K. Donadel (2009)
10.1002/jbm.a.35426
Effect of nano-hydroxyapatite-coated magnetic nanoparticles on axonal guidance growth of rat dorsal root ganglion neurons.
Meili Liu (2015)
10.1088/0957-4484/18/3/035603
Size-controlled synthesis of dextran sulfate coated iron oxide nanoparticles for magnetic resonance imaging.
B. R. Jarrett (2007)
Plasmon induced enhanced photocatalytic activity of gold loaded hydroxyapatite nanoparticles under visible light
S Mondal (2017)
10.1088/0957-4484/23/45/455104
Mechanisms of enhanced osteoblast gene expression in the presence of hydroxyapatite coated iron oxide magnetic nanoparticles.
N. Tran (2012)
10.1088/0957-4484/24/18/185102
Understanding magnetic nanoparticle osteoblast receptor-mediated endocytosis using experiments and modeling.
N. Tran (2013)
10.1088/0022-3727/36/13/201
TOPICAL REVIEW: Applications of magnetic nanoparticles in biomedicine
Q. Pankhurst (2003)
Bovine serum albumin-conjugated ferrimagnetic iron oxide nanoparticles to enhance the biocompatibility and magnetic hyperthermia
V Kalidasan (2016)
10.1109/TNB.2003.820279
Receptor-mediated targeting of magnetic nanoparticles using insulin as a surface ligand to prevent endocytosis
A. Gupta (2003)
10.1016/j.actbio.2011.06.038
A novel drug vehicle capable of ultrasound-triggered release with MRI functions.
Tse-Ying Liu (2011)
10.1016/J.JPBA.2004.03.004
Identification and quantitation of extractables from cellulose acetate butyrate (CAB) and estimation of their in vivo exposure levels.
Decheng Ma (2004)
10.1021/nn300042m
Silver-coated engineered magnetic nanoparticles are promising for the success in the fight against antibacterial resistance threat.
M. Mahmoudi (2012)
10.1002/cmmi.1473
Uniform mesoporous silica coated iron oxide nanoparticles as a highly efficient, nontoxic MRI T(2) contrast agent with tunable proton relaxivities.
Fei Ye (2012)
10.1039/C3CE26683D
Hollow magnetic hydroxyapatite microspheres with hierarchically mesoporous microstructure for pH-responsive drug delivery
Kaili Lin (2013)
Synthesis, characterization and in vitro cytotoxicity assessment of hydroxyapatite from different bio sources for tissue engineering application
S Mondal (2012)
10.1517/17425240802662795
Magnetic targeting for site-specific drug delivery: applications and clinical potential.
B. Polyak (2009)
10.1016/J.CARBPOL.2009.03.042
Synthesis and characterization of superparamagnetic nanoparticles coated with carboxymethyl starch (CMS) for magnetic resonance imaging technique
M. Saboktakin (2009)
10.1007/s13726-015-0370-z
Carboxymethyl starch-coated iron oxide magnetic nanoparticles: a potential drug delivery system for isoniazid
Chinmayee Saikia (2015)
10.4015/S1016237210001748
Evaluation of magnetic-hydroxyapatite nanoparticles for gene delivery carrier
H. Wu (2010)
10.1007/s10856-016-5704-7
Spherical porous hydroxyapatite granules containing composites of magnetic and hydroxyapatite nanoparticles for the hyperthermia treatment of bone tumor
M. Kamitakahara (2016)
Effect of nano-hydroxyapatitecoated magnetic nanoparticles on axonal guidance growth of rat dorsal root ganglion neurons
M Liu (2015)
10.3390/ijms13055554
Dextran and Polymer Polyethylene Glycol (PEG) Coating Reduce Both 5 and 30 nm Iron Oxide Nanoparticle Cytotoxicity in 2D and 3D Cell Culture
M. Yu (2012)
10.1016/J.MATERRESBULL.2014.06.018
Mesoporous Fe3O4/hydroxyapatite composite for targeted drug delivery
L. Gu (2014)
10.1016/S0142-9612(01)00267-8
Surface modification of superparamagnetic magnetite nanoparticles and their intracellular uptake.
Y. Zhang (2002)
10.1016/j.biomaterials.2009.05.038
A magnetic, luminescent and mesoporous core-shell structured composite material as drug carrier.
P. Yang (2009)
10.1016/j.ijpharm.2016.05.046
Doxorubicin loaded large-pore mesoporous hydroxyapatite coated superparamagnetic Fe3O4 nanoparticles for cancer treatment.
Negar Abbasi Aval (2016)
10.1016/J.MATLET.2012.01.129
A novel preparation of magnetic hydroxyapatite nanotubes
R. Singh (2012)
Mesoporous Fe 3 O 4 / hydroxyapatite composite for targeted drug delivery
L Gu (2014)
10.1179/1753555714Y.0000000202
Intercalative nanohybrid of DNA in laminated magnetic hydroxyapatite
G. F. Zuo (2015)
10.1021/jp803016n
Optimal design and characterization of superparamagnetic iron oxide nanoparticles coated with polyvinyl alcohol for targeted delivery and imaging.
M. Mahmoudi (2008)
10.1021/la503808d
Polyacrylic acid-coated iron oxide nanoparticles for targeting drug resistance in mycobacteria.
P. S. Padwal (2014)
10.1016/j.bone.2013.07.015
Modifying bone scaffold architecture in vivo with permanent magnets to facilitate fixation of magnetic scaffolds.
S. Panseri (2013)
10.2147/IJN.S29442
RGDS-functionalized polyethylene glycol hydrogel-coated magnetic iron oxide nanoparticles enhance specific intracellular uptake by HeLa cells
Caner Nazli (2012)
10.3390/molecules18077533
Synthesis, Surface Modification and Characterisation of Biocompatible Magnetic Iron Oxide Nanoparticles for Biomedical Applications
Mahnaz Mahdavi (2013)
10.1016/j.biomaterials.2013.12.064
Long-term biodistribution in vivo and toxicity of radioactive/magnetic hydroxyapatite nanorods.
Y. Liu (2014)
10.1016/j.ejpb.2017.03.014
pH responsive controlled release of anti‐cancer hydrophobic drugs from sodium alginate and hydroxyapatite bi‐coated iron oxide nanoparticles
D. C. Manatunga (2017)
Microsphere mediated delivery of recombinant AAV vectors in vitro and in vivo
C Mah (2000)
10.1039/c4cc06977c
Synthesis of iron oxide coated fluoridated HAp/Ln³⁺ (Ln = Eu or Tb) nanocomposites for biological applications.
J. Pan (2014)
Three - dimensional chitosannanohydroxyapatite composite scaffolds for bone tissue engineering
WW Thein-Han (2009)
10.1088/0957-4484/22/10/105708
The role of surface charge on the uptake and biocompatibility of hydroxyapatite nanoparticles with osteoblast cells.
L. Chen (2011)
10.1371/journal.pone.0158084
Magnetic Properties of Polyvinyl Alcohol and Doxorubicine Loaded Iron Oxide Nanoparticles for Anticancer Drug Delivery Applications
M. Nadeem (2016)
10.1002/jbm.a.34245
Processing-structure-functional property relationship in organic-inorganic nanostructured scaffolds for bone-tissue engineering: the response of preosteoblasts.
D. Depan (2012)
10.1155/2014/273082
Preparation of Chitosan Coated Magnetic Hydroxyapatite Nanoparticles and Application for Adsorption of Reactive Blue 19 and Ni2+ Ions
V. C. Nguyễn (2014)
10.1080/09506608.2015.1128310
Biocompatibility and mechanical behaviour of three-dimensional scaffolds for biomedical devices: process–structure–property paradigm
A. Kumar (2016)
10.1016/j.medengphy.2011.12.019
A new approach to scaffold fixation by magnetic forces: Application to large osteochondral defects.
A. Russo (2012)
10.1039/C3BM60086F
Magnetic nanocomposite of hydroxyapatite ultrathin nanosheets/Fe3O4 nanoparticles: microwave-assisted rapid synthesis and application in pH-responsive drug release.
F. Chen (2013)
Magnetism in medicine.
C. Breathnach (1983)
10.3390/ijms14059365
Simple and Rapid Synthesis of Magnetite/Hydroxyapatite Composites for Hyperthermia Treatments via a Mechanochemical Route
T. Iwasaki (2013)
10.1088/0957-4484/19/26/265101
Increased osteoblast density in the presence of novel calcium phosphate coated magnetic nanoparticles.
R. Pareta (2008)
10.1002/JBM.A.30857
Electrophoretic deposition of hydroxyapatite coating on Fecralloy and analysis of human osteoblastic cellular response.
Xingyuan Guo (2007)
10.1088/0957-4484/18/16/165601
A novel biomagnetic nanoparticle based on hydroxyapatite
H. Wu (2007)
10.1021/acsnano.6b08193
Protein Corona of Magnetic Hydroxyapatite Scaffold Improves Cell Proliferation via Activation of Mitogen-Activated Protein Kinase Signaling Pathway.
Y. Zhu (2017)
10.1111/IJAC.12553
Structure–Property Relationship in an Electroconductive Hydroxyapatite–Titanium Disilicide Composite
A. Kumar (2016)
10.1007/s10856-010-4090-9
Aqueous ferrofluids as templates for magnetic hydroxyapatite nanocomposites
A. Mir (2010)
10.1016/j.biomaterials.2011.08.032
The photoluminescence, drug delivery and imaging properties of multifunctional Eu3+/Gd3+ dual-doped hydroxyapatite nanorods.
Feng Chen (2011)
10.1021/acs.inorgchem.6b03143
Fe-Doping-Induced Magnetism in Nano-Hydroxyapatites.
V. Iannotti (2017)
10.1007/s40820-015-0065-1
Bovine Serum Albumin-Conjugated Ferrimagnetic Iron Oxide Nanoparticles to Enhance the Biocompatibility and Magnetic Hyperthermia Performance
Viveka Kalidasan (2016)
Hollow magnetic hydroxyapatite microspheres with hierarchically mesoporous microstructure for pHresponsive drug
K Lin (2013)
Al(OH) 3 facilitated synthesis of water-soluble, magnetic, radiolabelled and fluorescent hydroxyapatite nanoparticles
X Cui (2015)
10.1038/nmat2441
Complexity in biomaterials for tissue engineering.
Elsie S. Place (2009)
10.1016/j.msec.2016.01.071
Magnetic hydroxyapatite coatings as a new tool in medicine: A scanning probe investigation.
A. Gambardella (2016)
10.1016/j.saa.2011.11.047
Synthesis and spectroscopic characterization of magnetic hydroxyapatite nanocomposite using ultrasonic irradiation.
D. Gopi (2012)
10.1016/J.MATERRESBULL.2007.09.004
Substitution of manganese and iron into hydroxyapatite: Core/shell nanoparticles
W. Pon-On (2008)
10.1039/C4RA07318E
Facile in situ growth of Fe3O4 nanoparticles on hydroxyapatite nanorods for pH dependent adsorption and controlled release of proteins
G. Bharath (2014)
10.1016/j.ab.2008.12.032
Application of gelatin-coated magnetic particles for isolation of genomic DNA from bacterial cells.
S. Intorasoot (2009)
10.1016/j.msec.2017.04.030
Colloidal properties and in vitro evaluation of Hydroxy ethyl cellulose coated iron oxide particles for targeted drug delivery.
Maide Gökçe Bekaroğlu (2017)
10.1016/j.foodchem.2017.01.082
Covalent immobilization of lipase onto aminopropyl-functionalized hydroxyapatite-encapsulated-γ-Fe2O3 nanoparticles: A magnetic biocatalyst for interesterification of soybean oil.
W. Xie (2017)
10.1002/jbm.a.35664
Biological functionality of extracellular matrix-ornamented three-dimensional printed hydroxyapatite scaffolds.
A. Kumar (2016)
10.1021/JP5114027
Structural and Magnetic Phase Transformations of Hydroxyapatite-Magnetite Composites under Inert and Ambient Sintering Atmospheres
Sunil Kumar Boda (2015)
10.1021/LA010703+
Alkyl Phosphonate/Phosphate Coating on Magnetite Nanoparticles: A Comparison with Fatty Acids
Y. Sahoo (2001)
10.1016/J.CERAMINT.2014.03.124
Structural characterization of nanostructured hydroxyapatite–iron oxide composites
D. Trandafir (2014)
10.1007/S11837-009-0131-6
Three-dimensional chitosan-nanohydroxyapatite composite scaffolds for bone tissue engineering
W. W. Thein-Han (2009)
10.1039/C4BM00168K
The development, characterization, and cellular response of a novel electroactive nanostructured composite for electrical stimulation of neural cells.
D. Depan (2014)
10.1111/J.1551-2916.2011.05033.X
Synthesis and Characterization of Iron Oxide Embedded Hydroxyapatite Bioceramics
E. B. Ansar (2012)
Preparation and characterization of hydroxyapatite-coated iron oxide particles by spray-drying technique. An Acad Bras Ciênc
K Donadel (2009)
10.1088/0957-4484/22/1/015104
A conceptually new type of bio-hybrid scaffold for bone regeneration.
A. Tampieri (2011)
OH) 3 facilitated synthesis of water-soluble, magnetic, radiolabelled and fluorescent hydroxyapatite nanoparticles
X Cui (2015)
10.1002/CHIN.201630249
Gold Coated Magnetic Nanoparticles: From Preparation to Surface Modification for Analytical and Biomedical Applications
S. M. Silva (2016)
10.1016/j.colsurfb.2016.06.042
Different hydroxyapatite magnetic nanoparticles for medical imaging: Its effects on hemostatic, hemolytic activity and cellular cytotoxicity.
M. Laranjeira (2016)
10.1002/jbm.b.33836
Bone regeneration in a rabbit critical femoral defect by means of magnetic hydroxyapatite macroporous scaffolds.
A. Russo (2018)
10.4236/JMMCE.2012.111005
Studies on Processing and Characterization of Hydroxyapatite Biomaterials from Different Bio Wastes
S. Mondal (2012)
10.1016/J.CERAMINT.2016.08.165
Natural origin hydroxyapatite scaffold as potential bone tissue engineering substitute
Sudip Mondal (2016)
10.1016/j.nano.2013.05.014
Magnetic nanoparticle mediated transfection of neural stem cell suspension cultures is enhanced by applied oscillating magnetic fields.
C. F. Adams (2013)
10.1021/la2004134
Free-standing poly(L-lactic acid) nanofilms loaded with superparamagnetic nanoparticles.
S. Taccola (2011)
10.1016/j.biomaterials.2009.02.034
Magnetically targeted thrombolysis with recombinant tissue plasminogen activator bound to polyacrylic acid-coated nanoparticles.
Yunn-Hwa Ma (2009)
10.1021/ja1022267
Noninvasive remote-controlled release of drug molecules in vitro using magnetic actuation of mechanized nanoparticles.
Courtney R. Thomas (2010)
10.1016/j.actbio.2011.09.032
Intrinsic magnetism and hyperthermia in bioactive Fe-doped hydroxyapatite.
A. Tampieri (2012)
10.2147/IJN.S23952
Laser and radiofrequency-induced hyperthermia treatment via gold-coated magnetic nanocomposites
A. A. Elsherbini (2011)
10.1006/JCIS.1998.5850
Phosphorylcholine Coating of Iron Oxide Nanoparticles.
Denizot (1999)
10.1021/CM4007298
Magnetic bioactive and biodegradable hollow fe-doped hydroxyapatite coated poly(l -lactic) acid micro-nanospheres
M. Iafisco (2013)
10.1016/J.CERAMINT.2013.09.137
Development of a dual-functional Pt-Fe-HAP magnetic nanoparticles application for chemo-hyperthermia treatment of cancer
Ching Li Tseng (2014)



This paper is referenced by
10.1016/J.CERAMINT.2018.08.045
Biomimetic synthesis of metal–hydroxyapatite (Au-HAp, Ag-HAp, Au-Ag-HAp): Structural analysis, spectroscopic characterization and biomedical application
Hyehyun Kim (2018)
10.3390/biology9110357
Evidence of Modular Responsiveness of Osteoblast-Like Cells Exposed to Hydroxyapatite-Containing Magnetic Nanostructures
Stefania Scialla (2020)
10.1016/J.JNUCMAT.2018.11.026
Adsorption and immobilization of radioactive ionic-corrosion-products using magnetic hydroxyapatite and cold-sintering for nuclear waste management applications
Suriya Venkatesan (2019)
10.1007/s10565-020-09527-3
Pulsed laser deposition temperature effects on strontium-substituted hydroxyapatite thin films for biomedical implants
A. Bonis (2020)
10.1016/J.MATCHEMPHYS.2019.121884
Corrosion behavior and characterization of HA/Fe3O4/CS composite coatings on AZ91 Mg alloy by electrophoretic deposition
S. Singh (2019)
10.3390/ma11112081
Cationic Substitutions in Hydroxyapatite: Current Status of the Derived Biofunctional Effects and Their In Vitro Interrogation Methods
T. Tite (2018)
10.1039/C9NJ02510C
Fabrication of core–shell CoFe2O4@HAp nanoparticles: a novel magnetic platform for biomedical applications
D. Karthickraja (2019)
10.1016/J.CERAMINT.2019.05.260
Nanostructured hollow hydroxyapatite fabrication by carbon templating for enhanced drug delivery and biomedical applications
Sudip Mondal (2019)
10.1016/J.APMT.2019.01.002
Enhanced angiogenesis of biodegradable iron-doped octacalcium phosphate/poly(lactic-co-glycolic acid) scaffold for potential cancerous bone regeneration
Haishan Shi (2019)
10.21517/1992-7223-2019-11-12-88-94
Синтез и свойства композитов на основе гидроксиапатита, магнитита и 2-ариламинопиримидина
Ж. В. Игнатович (2020)
10.22038/NMJ.2020.07.0004
Fabrication of chitosan-hyaluronic acid nanoparticles and encapsulation into nanoparticles of dinitrosyl iron complexes as potential cardiological drugs
N. Akentieva (2020)
10.1016/J.JECE.2019.103338
Enhanced adsorption of dyes on microwave-assisted synthesized magnetic zeolite-hydroxyapatite nanocomposite
Farhad Piri (2019)
10.1016/j.ceramint.2020.01.062
Manganese behavior in hydroxyapatite crystals revealed by X-ray difference Fourier maps
P. H. Oliveira (2020)
10.1016/j.aca.2020.09.006
Mono-dispersed nano-hydroxyapatite based MRI probe with tetrahedral DNA nanostructures modification for in vitro tumor cell imaging.
Yaqin He (2020)
10.1016/J.MSEC.2019.03.066
Mesoporous superparamagnetic hydroxyapatite nanocomposite: A multifunctional platform for synergistic targeted chemo-magnetotherapy.
Azadeh Izadi (2019)
10.17537/ICMBB18.83
Density functional study of magnetic substitutions in hydroxyapatite
E. Paramonova (2018)
10.1016/j.jallcom.2019.152786
The structural and magnetic properties of the nano-CoFe2O4 ferrite prepared by sol-gel auto-combustion technique
Mohammed S. Al Maashani (2020)
10.1016/J.JDDST.2019.101131
3D hydroxyapatite scaffold for bone regeneration and local drug delivery applications
Sudip Mondal (2019)
10.3389/fchem.2020.00124
Recent Advances on Magnetic Sensitive Hydrogels in Tissue Engineering
Zhongyang Liu (2020)
10.1016/j.tsf.2020.137801
Electrophoretic deposition of hydroxyapatite-iron oxide-chitosan composite coatings on Ti–13Nb–13Zr alloy for biomedical applications
Sandeep Singh (2020)
10.1016/J.CERAMINT.2018.05.248
Nano-hydroxyapatite bioactive glass composite scaffold with enhanced mechanical and biological performance for tissue engineering application
Sudip Mondal (2018)
10.1016/J.MATCHEMPHYS.2019.121868
Fabrication of microporous bacterial cellulose embedded with magnetite and hydroxyapatite nanocomposite scaffold for bone tissue engineering
Selorm Torgbo (2019)
10.1016/j.heliyon.2020.e04928
One-pot hydrothermal synthesis of a magnetic hydroxyapatite nanocomposite for MR imaging and pH-Sensitive drug delivery applications
Mehraneh Kermanian (2020)
Semantic Scholar Logo Some data provided by SemanticScholar