Online citations, reference lists, and bibliographies.

Starch-mediated Synthesis Of Mono- And Bimetallic Silver/gold Nanoparticles As Antimicrobial And Anticancer Agents

Diana Lomelí-Marroquín, David Medina Cruz, Alfonso Nieto-Argüello, Ada Vernet Crua, Junjiang Chen, Alejandro Torres-Castro, Thomas J. Webster, Jorge Luis Cholula-Diaz
Published 2019 · Materials Science, Medicine
Cite This
Download PDF
Analyze on Scholarcy
Share
Background and aim Bimetallic silver/gold nanosystems are expected to significantly improve therapeutic efficacy compared to their monometallic counterparts by maintaining the general biocompatibility of gold nanoparticles (AuNPs) while, at the same time, decreasing the relatively high toxicity of silver nanoparticles (AgNPs) toward healthy human cells. Thus, the aim of this research was to establish a highly reproducible one-pot green synthesis of colloidal AuNPs and bimetallic Ag/Au alloy nanoparticles (NPs; Ag/AuNPs) using starch as reducing and capping agent. Methods The optical properties, high reproducibility, stability and particle size distribution of the colloidal NPs were analyzed by ultraviolet (UV)–visible spectroscopy, dynamic light scattering (DLS) and ζ-potential. The presence of starch as capping agent was determined by Fourier transform infrared (FT-IR) spectroscopy. The structural properties were studied by X-ray diffraction (XRD). Transmission electron microscopy (TEM) imaging was done to determine the morphology and size of the nanostructures. The chemical composition of the nanomaterials was determined by energy-dispersive X-ray spectroscopy (EDS) and inductively coupled plasma mass spectrometry (ICP-MS) analysis. To further study the biomedical applications of the synthesized nanostructures, antibacterial studies against multidrug-resistant (MDR) Escherichia coli and methicillin-resistant Staphylococcus aureus (MRSA) were conducted. In addition, the NPs were added to the growth media of human dermal fibroblast (HDF) and human melanoma cells to show their cytocompatibility and cytotoxicity, respectively, over a 3-day experiment. Results UV–visible spectroscopy confirmed the highly reproducible green synthesis of colloidal AuNPs and Ag/AuNPs. The NPs showed a face-centered cubic crystal structure and an icosahedral shape with mean particle sizes of 28.5 and 9.7 nm for AuNPs and Ag/AuNPs, respectively. The antibacterial studies of the NPs against antibiotic-resistant bacterial strains presented a dose-dependent antimicrobial behavior. Furthermore, the NPs showed cytocompat-ibility towards HDF, but a dose-dependent anticancer effect was found when human melanoma cells were grown in presence of different NP concentrations for 72 hours. Conclusion In this study, mono- and bimetallic NPs were synthesized for the first time using a highly reproducible, environmentally friendly, cost-effective and quick method and were successfully characterized and tested for several anti-infection and anticancer biomedical applications.
This paper references
10.1021/JP8082425
Size Evaluation of Gold Nanoparticles by UV−vis Spectroscopy
Vincenzo Amendola (2009)
Antimicrobial effects of silver nanoparticles. Nanomedicine
JS Kim (2007)
10.1002/SMLL.200701295
Shape Control of Colloidal Metal Nanocrystals
A. Tao (2008)
10.1016/j.jsps.2014.11.013
Biosynthesis of metallic nanoparticles using plant derivatives and their new avenues in pharmacological applications – An updated report
Palaniselvam Kuppusamy (2016)
10.1021/cg9007685
Green Synthesis of Au Nanostructures at Room Temperature Using Biodegradable Plant Surfactants
Mallikarjuna N. Nadagouda (2009)
10.1002/smll.200400053
Extracellular biosynthesis of bimetallic Au-Ag alloy nanoparticles.
Satyajyoti Senapati (2005)
10.1007/978-4-431-56556-7
Noble Metal Nanoparticles: Preparation, Composite Nanostructures, Biodecoration and Collective Properties
Ignác Capek (2017)
CRC Handbook of Chemistry and Physics
D. Lide (1996)
10.1016/j.colsurfb.2017.12.051
Synthesis of colloidal silver nanoparticle clusters and their application in ascorbic acid detection by SERS.
J. L. Cholula-Diaz (2018)
10.1016/S0144-8617(01)00187-4
The preparation and characterisation of a series of chemically modified potato starches
J. M. Fang (2002)
10.1021/ac0702084
Determination of size and concentration of gold nanoparticles from UV-vis spectra.
Wolfgang Haiss (2007)
10.1186/1556-276X-7-576
Synthesis and characterization of polysaccharide-maghemite composite nanoparticles and their antibacterial properties
Simona Liliana Iconaru (2012)
10.1007/s11051-010-9911-8
Toxicity and cellular uptake of gold nanoparticles: what we have learned so far?
Alaaldin AlKilany (2010)
10.1002/STAR.201200252
Synthesis and characterization of silver nanoparticles using water-soluble starch and its antibacterial activity on Staphylococcus aureus
G. Valencia (2013)
10.1021/la400355u
Preparation of bimetallic nanoparticles using a facile green synthesis method and their application.
B. Xia (2013)
10.1039/B512540E
A simple and “green” method for the synthesis of Au, Ag, and Au–Ag alloy nanoparticles
P. Raveendran (2006)
10.1007/s11356-017-9329-2
Green synthesis and characterization of gold and silver nanoparticles using Mussaenda glabrata leaf extract and their environmental applications to dye degradation
Sijo Francis (2017)
10.1016/j.carres.2006.04.042
A novel one-pot 'green' synthesis of stable silver nanoparticles using soluble starch.
N. Vigneshwaran (2006)
10.1039/B911111E
Green synthesis of gold nanoparticles with starch–glucose and application in bioelectrochemistry
C. Engelbrekt (2009)
10.1093/clinids/2.1.129
On the antibacterial action of cultures of a penicillium, with special reference to their use in the isolation of B. influenzae. 1929.
A. Fleming (2001)
10.1039/c4cp02208d
Highly monodisperse multiple twinned AuCu-Pt trimetallic nanoparticles with high index surfaces.
Subarna Khanal (2014)
10.1002/jor.23656
Bacteria antibiotic resistance: New challenges and opportunities for implant-associated orthopedic infections.
Bingyun Li (2018)
10.3390/nano6110209
Green Synthesis of Iron Nanoparticles and Their Environmental Applications and Implications
Sadia Saif (2016)
10.1039/C5TB00644A
Nanostructure of wet-chemically prepared, polymer-stabilized silver-gold nanoalloys (6 nm) over the entire composition range.
Simon Ristig (2015)
10.3390/ijms14034817
Active Silver Nanoparticles for Wound Healing
Chiara Rigo (2013)
10.1016/j.nano.2006.12.001
Antimicrobial effects of silver nanoparticles.
J. Kim (2007)
Synthesis of silver nanoparticles: chemical, physical and biological methods
S. Iravani (2014)
10.1039/C1GC15386B
Green synthesis of metal nanoparticles using plants
Siavash Iravani (2011)
Starch-templated biosynthesis of gold nanoflowers for in vitro antimicrobial and anticancer activities
D Borah (2018)
10.1177/2042098614554919
Antimicrobial resistance: risk associated with antibiotic overuse and initiatives to reduce the problem
Carl Llor (2014)
10.1021/nn800596w
Cytotoxicity and genotoxicity of silver nanoparticles in human cells.
P. V. AshaRani (2009)
10.2147/IJN.S121956
The antimicrobial activity of nanoparticles: present situation and prospects for the future
L. Wang (2017)
10.1021/ja029267j
Completely "green" synthesis and stabilization of metal nanoparticles.
P. Raveendran (2003)
10.18632/oncotarget.23859
Anticancer activity of biogenerated silver nanoparticles: an integrated proteomic investigation
Miriam Buttacavoli (2018)
10.7759/cureus.1403
A Review on Antibiotic Resistance: Alarm Bells are Ringing
Sojib Bin Zaman (2017)
10.31399/asm.hb.v13b.a0006542
ELECTROCHEMICAL SERIES
P. Vanýsek (2010)
10.3390/nano6040071
Gold Nanoparticles: An Efficient Antimicrobial Agent against Enteric Bacterial Human Pathogen
Shahzadi Shamaila (2016)
10.22037/IJPR.2016.1926
Rapid Extracellular Biosynthesis of Silver Nanoparticles by Cunninghamella phaeospora Culture Supernatant
Mohamed Ghareib (2016)
10.1166/JNN.2014.8900
Biological applications of gold nanoparticles.
Monic Shah (2014)
10.1038/091477b0
The Reflection of X-Rays by Crystals
W. Bragg (1913)
10.3892/mco.2017.1399
Magnetic nanoparticles in cancer diagnosis, drug delivery and treatment.
Meijia Wu (2017)
10.1016/J.COLSURFA.2012.09.005
Synthesis and characterization of Ag/Au alloy and core(Ag)–shell(Au) nanoparticles
Edit Csapó (2012)
10.3390/ijms18010120
The Role of Reactive Oxygen Species (ROS) in the Biological Activities of Metallic Nanoparticles
Ahmed Abdal Dayem (2017)
Toxicity and Environmental Risks of Nanomaterials : Challenges and Future Needs
Patnam Padma Latha (2016)
Bestimmung der Größe und der inneren Struktur von Kolloidteilchen mittels Röntgenstrahlen
Philipp Scherrer (2017)
10.1371/journal.pone.0178691
The use of Gompertz models in growth analyses, and new Gompertz-model approach: An addition to the Unified-Richards family
Kathleen M C Tjørve (2017)
10.1007/BF01174717
High-temperature thermal expansion of six metallic elements measured by dilatation method and X-ray diffraction
In-Kook Suh (1988)
10.2147/NSA.S99986
Synthesis, characterization, applications, and challenges of iron oxide nanoparticles
Attarad Ali (2016)
10.2147/IJN.S137703
Extracellular biosynthesis of silver nanoparticles using the cell-free filtrate of nematophagous fungus Duddingtonia flagrans
Laryssa Pinheiro Costa Silva (2017)
10.1021/nl025774n
Solution-Phase Synthesis of Sub-10 nm Au−Ag Alloy Nanoparticles
M. Mallin (2002)
10.1186/s12941-016-0164-y
A combination of silver nanoparticles and visible blue light enhances the antibacterial efficacy of ineffective antibiotics against methicillin-resistant Staphylococcus aureus (MRSA)
Fatma Elzahraa Akram (2016)
10.1016/j.carbpol.2014.04.105
One pot green synthesis of Ag, Au and Au-Ag alloy nanoparticles using isonicotinic acid hydrazide and starch.
Sampath Malathi (2014)
10.12688/f1000research.9690.1
Nanoparticle-based drug delivery systems: What can they really do in vivo?
Yi-Feng Wang (2017)
The antibiotic resistance crisis: part 1: causes and threats.
C. Ventola (2015)
10.1002/bit.260130504
Electrochemical measurements with glucose oxidase immobilized in polyacrylamide gel: Constant current voltametry
L. Wingard (1971)
10.1002/wnan.1322
Therapeutic gold, silver, and platinum nanoparticles.
Miko Yamada (2015)
Anomalous growth-behavior of Pd-Au and Ag-Au alloy particles during vapor-deposition on carbon substrates at elevatedtemperatures
AA Schmidt (1995)
10.1039/C5RA16473G
Controlled modification of starch in the synthesis of gold nanoparticles with tunable optical properties and their application in heavy metal sensing
Deependra Kumar Ban (2015)
10.1080/23312009.2016.1192522
Synthesis and antimicrobial effects of colloidal gold nanoparticles against prevalent waterborne bacterial pathogens
Rajesh Kumar (2016)
10.1039/b607128g
The role of twinning in shape evolution of anisotropic noble metal nanostructures
J. L. Elechiguerra (2006)
10.1128/MMBR.00016-10
Origins and Evolution of Antibiotic Resistance
J. Davies (2010)
thesis and characterization of polysaccharide - maghemite composite nanoparticles and their antibacterial properties
SL Iconaru (2012)
10.1007/s11051-018-4354-8
Synthesis and characterization of PVP-coated tellurium nanorods and their antibacterial and anticancer properties
Christopher D. Brown (2018)
10.2147/IJN.S76104
Magnetic nanoparticles enhance the anticancer activity of cathelicidin LL-37 peptide against colon cancer cells
Katarzyna Niemirowicz (2015)
10.1038/srep39466
Selective in vitro photothermal nano-therapy of MRSA infections mediated by IgG conjugated gold nanoparticles
Lucian Mocan (2016)
10.1038/srep32631
Understanding the Solvent Molecules Induced Spontaneous Growth of Uncapped Tellurium Nanoparticles
Jun Liu (2016)
10.1002/jbm.a.36347
Synthesis and characterization of biogenic selenium nanoparticles with antimicrobial properties made by Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), Escherichia coli, and Pseudomonas aeruginosa.
David Medina Cruz (2018)
10.1002/STAR.201200255
Green synthesis method of silver nanoparticles using starch as capping agent applied the methodology of surface response
Lesli Ortega-Arroyo (2013)



This paper is referenced by
Semantic Scholar Logo Some data provided by SemanticScholar