← Back to Search
Oxidative Stress In Bacteria And Protein Damage By Reactive Oxygen Species.
E. Cabiscol, J. Tamarit, J. Ros
Published 2000 · Medicine, Biology
Download PDFAnalyze on Scholarcy
The advent of O2 in the atmosphere was among the first major pollution events occurred on earth. The reaction between ferrous iron, very abundant in the reductive early atmosphere, and oxygen results in the formation of harmful superoxide and hydroxyl radicals, which affect all macromolecules (DNA, lipids and proteins). Living organisms have to build up mechanisms to protect themselves against oxidative stress, with enzymes such as catalase and superoxide dismutase, small proteins like thioredoxin and glutaredoxin, and molecules such as glutathione. Bacterial genetic responses to oxidative stress are controlled by two major transcriptional regulators (OxyR and SoxRS). This paper reviews major key points in the generation of reactive oxygen species in bacteria, defense mechanisms and genetic responses to oxidative stress. Special attention is paid to the oxidative damage to proteins.
This paper references
The crystal structure of Dps, a ferritin homolog that binds and protects DNA
R. Grant (1998)
Superoxide sensitivity of the Escherichia coli aconitase.
P. R. Gardner (1991)
Nucleotide sequence of Escherichia coli katE, which encodes catalase HPII.
I. von Ossowski (1991)
Activation of the OxyR transcription factor by reversible disulfide bond formation.
M. Zheng (1998)
Protein Oxidation in Aging, Disease, and Oxidative Stress*
B. S. Berlett (1997)
Biochemistry and pathology of radical-mediated protein oxidation.
R. Dean (1997)
Oxidative modification of glutamine synthetase. I. Inactivation is due to loss of one histidine residue.
R. L. Levine (1983)
Degradation of oxidized proteins in mammalian cells
T. Grune (1997)
Oxidatively denatured proteins are degraded by an ATP-independent proteolytic pathway in Escherichia coli.
K. Davies (1988)
Intracellular proteolytic systems may function as secondary antioxidant defenses: an hypothesis.
K. Davies (1986)
Metal-catalyzed oxidation of Fe2+ dehydrogenases. Consensus target sequence between propanediol oxidoreductase of Escherichia coli and alcohol dehydrogenase II of Zymomonas mobilis.
E. Cabiscol (1994)
Repair of oxidative damage to DNA: enzymology and biology.
B. Demple (1994)
Oxidation of free amino acids and amino acid residues in proteins by radiolysis and by metal-catalyzed reactions.
E. Stadtman (1993)
Degradation of oxidatively denatured proteins in Escherichia coli.
K. Davies (1988)
Oxidation of proteins by mixed-function oxidation systems: implication in protein turnover, ageing and neutrophil function
E. Stadtman (1986)
Chaperone Activity with a Redox Switch
U. Jakob (1999)
Measurement of radiation-induced damage to DNA at the molecular level.
M. Dizdaroglu (1992)
Inducible repair of oxidative DNA damage in Escherichia coli
B. Demple (1983)
Redox Signal Transduction: Mutations Shifting [2Fe-2S] Centers of the SoxR Sensor-Regulator to the Oxidized Form
E. Hidalgo (1997)
Selective inactivation of alpha-ketoglutarate dehydrogenase and pyruvate dehydrogenase: reaction of lipoic acid with 4-hydroxy-2-nonenal.
K. Humphries (1998)
Escherichia coli expresses a copper- and zinc-containing superoxide dismutase.
L. Benov (1994)
Control of Escherichia coli superoxide dismutase (sodA and sodB) genes by the ferric uptake regulation (fur) locus.
E. C. Niederhoffer (1990)
Metabolic Sources of Hydrogen Peroxide in Aerobically Growing Escherichia coli(*)
B. González-Flecha (1995)
Positive control of a regulon for defenses against oxidative stress and some heat-shock proteins in Salmonella typhimurium
Michael F. Christman (1985)
Inactivation of glucose-6-phosphate dehydrogenase by 4-hydroxy-2-nonenal. Selective modification of an active-site lysine.
L. Szweda (1993)
Role of Escherichia coli rpoS and associated genes in defense against oxidative damage.
A. Eisenstark (1996)
Oxidative stress responses in Escherichia coli and Salmonella typhimurium.
S. Farr (1991)
Methionine residues as endogenous antioxidants in proteins.
R. L. Levine (1996)
Proteasomes: multicatalytic proteinase complexes.
A. Rivett (1993)
Inactivation of key metabolic enzymes by mixed-function oxidation reactions: possible implication in protein turnover and ageing.
L. Fucci (1983)
Turnover of bacterial glutamine synthetase: oxidative inactivation precedes proteolysis.
R. L. Levine (1981)
Oxidative modification of glutamine synthetase. II. Characterization of the ascorbate model system.
R. L. Levine (1983)
Differential susceptibility of plasma proteins to oxidative modification: examination by western blot immunoassay.
E. Shacter (1994)
Sequence of a peptide susceptible to mixed-function oxidation. Probable cation binding site in glutamine synthetase.
J. Farber (1986)
Metal ion-catalyzed oxidation of proteins: biochemical mechanism and biological consequences.
E. Stadtman (1990)
Regulation of catalase synthesis in Salmonella typhimurium.
G. Finn (1975)
Regulation of Gene Expression in Escherichia coli
E. C. Lin (1996)
Regulation of the OxyR transcription factor by hydrogen peroxide and the cellular thiol-disulfide status.
F. Åslund (1999)
Damage to plasmid DNA by singlet oxygen and its protection.
H. Sies (1993)
Adaptive responses and oxidative stress
DR Crawford (1994)
The role of O2.- in the production of HO.: in vitro and in vivo.
S. Liochev (1994)
Identification of the Major Oxidatively Damaged Proteins inEscherichia coli Cells Exposed to Oxidative Stress*
J. Tamarit (1998)
Singlet oxygen induced DNA damage.
H. Sies (1992)
Oxidatively denaturated proteins are degraded by an ATP-independent proteolytic pathway in escherichia coli
K. Davies (1988)
The oxidative stress response in Bacillus subtilis.
B. Dowds (1994)
Interaction of six global transcription regulators in expression of manganese superoxide dismutase in Escherichia coli K-12.
I. Compan (1993)
Paraquat regulation of hmp (flavohemoglobin) gene expression in Escherichia coli K-12 is SoxRS independent but modulated by sigma S.
J. Membrillo-Hernández (1997)
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes.
H. Esterbauer (1991)
Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: implications for degradation of oxidized proteins.
K. Iwai (1998)
Carbonyl assays for determination of oxidatively modified proteins.
R. L. Levine (1994)
This paper is referenced by
Genome-wide Examination of the Natural Solar Radiation Response in Shewanella oneidensis MR-1
X. Qiu (2005)
Quantitative proteomic analysis of the interaction between the endophytic plant-growth-promoting bacterium Gluconacetobacter diazotrophicus and sugarcane.
Letícia M S Lery (2011)
Characterization of the Aerobic Oxidation of cis-Dichloroethene and Vinyl Chloride in Support of Bioremediation of Chloroethene-Contaminated Sites
J. Gossett (2004)
Studies to elucidate the mechanism of reduced flavin transfer in the alkanesulfonate monooxygenase system from Escherichia coli
Kholis Abdurachim (2007)
The Monofunctional Catalase KatE of Xanthomonas axonopodis pv. citri Is Required for Full Virulence in Citrus Plants
M. Tondo (2010)
Characterization and Modification of the Zinc Sensor ZapCY2 for Improved Nickel Binding
Farah Badr (2017)
Comparative photoactivity and antibacterial properties of C60 fullerenes and titanium dioxide nanoparticles.
L. Brunet (2009)
Protein oxidation: an overview of metabolism of sulphur containing amino acid, cysteine.
Saheem Ahmad (2017)
CHLOROFORM FRACTION OF PARKIA JAVANICA BARK POSSESSES ANTIBACTERIAL ACTIVITY AGAINST MULTIDRUG RESISTANT GRAM NEGATIVE BACTERIA PREDOMINANTLY FOUND IN SKIN WOUND
Shilpi Rani Saha (2018)
RpoS and oxidative stress conditions regulate succinyl‐CoA: 3‐ketoacid‐coenzyme A transferase (SCOT) expression in Burkholderia pseudomallei
P. Chutoam (2013)
Nuevos aspectos del control del metabolismo en "Pseudomonas putida" KT2440: metabolismo del ácido fenilacético y papel del gen apaH
Loreine Josélyn Agullo Carvajal (2014)
Characterization of the Hydrogen Peroxide Stress Responses of Bifidobacterium longum and Bifidobacterium animalis subsp. lactis
T. Oberg (2013)
A Transcriptomic Analysis of Salmonella enterica Newport In Planta and after Postharvest Sanitization
L. Dunn (2017)
Mechanism of SigR inhibition by the anti-sigma factor RsrA from Streptomyces coelicolor
C. Kleanthous (2015)
Comparison of Macromolecular Oxidation by Reactive Oxygen Species in Three Bacterial Genera Exposed to Different Antibiotics
P. Páez (2011)
Production of Chitosanase by Lentzea sp. OUR-I1 Using Acid-Pretreated Shrimp Shell in an Air-Lift Bioreactor and the Feasibility of Utilizing the Residual Biomass
Wasana Suyotha (2020)
Biosynthesis of Silver Nanoparticles by Methylophilus quaylei , Characterization and Its Impact on Established Biofilms
Abir M. H. A. Mohamed (2020)
Lavender essential oil induces oxidative stress which modifies the bacterial membrane permeability of carbapenemase producing Klebsiella pneumoniae
Shun-Kai Yang (2020)
Morphologies controlled ZnO for inactivation of multidrug resistant pseudomonas aeruginosa in solar light.
S. K. Ray (2019)
Fe3O4@GO magnetic nanocomposites protect mesenchymal stem cells and promote osteogenic differentiation of rat bone marrow mesenchymal stem cells.
H. Zhang (2020)
Copper stress by nutritional immunity activates the CusS-CusR two-component system that contributes to Vibrio alginolyticus anti-host response but affects virulence-related properties
Rongchao He (2020)
In vitro antimicrobial effects and mechanism of air plasma‐activated water on Staphylococcus aureus biofilm
Zimu Xu (2020)
Inaktivierung von Bakterien auf einer photodynamisch aktiven Oberfläche mittels unterschiedlicher Photosensibilisatoren
Lisa Rahel de Jonge (2013)
Production, characterization, cloning and sequence analysis of a monofunctional catalase from Serratia marcescens SYBC08
Hua-Wei Zeng (2011)
Examination of the Genome-Wide Transcriptional Response of Escherichia coli O157:H7 to Cinnamaldehyde Exposure
J. Visvalingam (2012)
Cupriavidus pinatubonensis AEO106 deals with copper-induced oxidative stress before engaging in biodegradation of the herbicide 4-chloro-2-methylphenoxyacetic acid
N. B. Svenningsen (2017)
Rhodobacter sp. Rb3, an aerobic anoxygenic phototroph which thrives in the polyextreme ecosystem of the Salar de Huasco, in the Chilean Altiplano
V. Pérez (2018)
Transcriptional response of Enterococcus faecalis to sunlight.
L. Sassoubre (2014)
Potential drivers of microbial community structure and function in Arctic spring snow
Lorrie Maccario (2014)
Complete genome sequencing and analysis of endophytic Sphingomonas sp. LK11 and its potential in plant growth
S. Asaf (2018)
Taxonomic and metabolic shifts in the Coorong bacterial metagenome driven by salinity and external inputs
K. Newton (2018)
Interaction Between Copperoxide Nanoparticles and Plants: Uptake, Accumulation and Phytotoxicity
Abreeq Fatima (2020)See more