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Effect Of Pre- And Postganglionic Lesioning Of The Trigeminal Nerve On Cerebral Blood Flow And Glucose Metabolism Following A Subarachnoid Haemorrhage In The Squirrel Monkey.

Y. Shiokawa, T. Delgado-Zygmunt, M. Arbab, N. A. Svendgaard
Published 1992 · Medicine

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Simultaneous cerebral blood flow (CBF) and glucose metabolism (CMRglu) studies with a double isotope autoradiographic technique were applied to squirrel monkeys submitted to a unilateral pre- or postganglionic trigeminal lesion. The CBF values were not affected following a pre- or postganglionic lesion per se. In contrast, there was a global increase in the cerebral glucose uptake of about 50% as compared to controls following both kinds of lesions. Following a subarachnoid haemorrhage (SAH) 2-4 weeks after pre- or postganglionic trigeminal lesioning, there was a decrease in CBF similar to that seen in the control group. In the animals with a preganglionic lesion, the 50% increase in glucose uptake was not further augmented by a SAH and the increase in CMRglu was comparable to that found in control SAH animals. In the postganglionically lesioned monkeys, a SAH induced an additional increase in glucose uptake of about 50%. The findings suggest that the trigeminal system is involved in the regulation of cerebral metabolism via a brainstem centre.
This paper references
10.1111/J.1748-1716.1990.TB08851.X
Effect on cortical blood flow of electrical stimulation of trigeminal cerebrovascular nerve fibres in the rat.
N. Suzuki (1990)
10.1016/0306-4522(86)90293-9
Origin and distribution of cerebral vascular innervation from superior cervical, trigeminal and spinal ganglia investigated with retrograde and anterograde WGA-HRP tracing in the rat
M. A. Arbab (1986)
10.1002/ANA.410250212
Subarachnoid blood and headache: Altered trigeminal tachykinin gene expression
M. D. Linnik (1989)
10.1227/00006123-198204000-00019
Timing of aneurysm surgery.
N. F. Kassell (1982)
10.1002/ANA.410040402
Local cerebral glucose utilization in the normal conscious macaque monkey
C. Kennedy (1978)
10.1152/AJPCELL.1978.234.3.C59
Insulin effects on monovalent cation transport and Na-K-ATPase activity.
T. Hougen (1978)
10.1113/jphysiol.1981.sp013862
Substance P: immunohistochemical localization and effect upon cat pial arteries in vitro and in situ.
L. Edvinsson (1981)
10.3171/JNS.1972.37.1.0036
Regional cerebral blood flow studies in subarachnoid hemorrhage.
M. Heilbrun (1972)
10.3171/JNS.1972.37.3.0316
Cerebral blood flow following induced subarachnoid hemorrhage in the monkey.
K. Petruk (1972)
10.1038/jcbfm.1986.106
Subarachnoid Hemorrhage in the Rat: Cerebral Blood Flow and Glucose Metabolism during the Late Phase of Cerebral Vasospasm
T. Delgado (1986)
10.1002/ANA.410140509
Herpes zoster ophthalmicus and delayed contralateral hemiparesis caused by cerebral angiitis: Diagnosis and management approaches
D. Hilt (1983)
10.1038/jcbfm.1986.107
Subarachnoid Hemorrhage in the Rat: Cerebral Blood Flow and Glucose Metabolism after Selective Lesions of the Catecholamine Systems in the Brainstem
T. Delgado (1986)
10.1002/CNE.902230105
Trigeminal projections to supratentorial pial and dural blood vessels in cats demonstrated by horseradish peroxidase histochemistry
M. Mayberg (1984)
10.1016/0361-9230(87)90084-0
Local brainstem glucose utilization in the squirrel monkey
K. Brizzee (1987)
10.1001/ARCHNEUR.1960.03840090124020
Handbook of Physiology.
F. Plum (1960)
10.1016/0006-8993(86)90508-1
Immunoelectron microscopic study of substance P-containing fibers in feline cerebral arteries
L. Liu-Chen (1986)
10.1038/jcbfm.1990.70
Origins and Pathways of Choline Acetyltransferase—Positive Parasympathetic Nerve Fibers to Cerebral Vessels in Rat
N. Suzuki (1990)
Neural regulation of brain circulation
C. Owman (1986)
10.1111/J.1748-1716.1980.TB06540.X
Rapid simultaneous determination of regional blood flow and blood-brain glucose transfer in brain of rat.
A. Gjedde (1980)
10.1152/AJPCELL.1988.255.1.C1
In search of a second messenger for insulin.
A. Saltiel (1988)
10.1002/AJA.1001440208
Capillary innervation in the mammalian central nervous system: an electron microscopic demonstration.
M. Rennels (1975)
10.1002/CNE.902710310
Cerebral arterial innervation by nerve fibers containing calcitonin gene‐related peptide (CGRP): I. Distribution and origin of CGRP perivascular innervation in rat
S. Tsai (1988)
10.1038/jcbfm.1990.68
Selective Electrical Stimulation of Postganglionic Cerebrovascular Parasympathetic Nerve Fibers Originating from the Sphenopalatine Ganglion Enhances Cortical Blood Flow in the Rat
N. Suzuki (1990)
10.1038/jcbfm.1985.42
Evidence for the Presence of Cholinergic Nerves in Cerebral Arteries: An Immunohistochemical Demonstration of Choline Acetyltransferase
A. Saito (1985)
10.1038/jcbfm.1985.36
Double-Tracer Study of the Fine Regional Blood—Brain Glucose Transfer in the Rat by Computer-Assisted Autoradiography
A. Gjedde (1985)
10.1515/9783110858853-053
Serial biochemical changes in the cerebrospinal fluid during the early stage of subarachnoid haemorrhage: relationship with cerebral vasospasm
A. Pasqualin (1985)
Trigeminal nerve pathways to the cerebral arteries in monkeys.
G. Ruskell (1987)
10.1212/WNL.20.8.802
Regional cerebral blood flow during acute ischemia Correlation of autoradiographic measurements with observations of cortical microcirculation
R. Blair (1970)
10.1016/0006-8993(86)90690-6
Stimulation of the Trigeminal ganglion increases flow in the extracerebral but not the cerebral circulation of the monkey
P. Goadsby (1986)
10.1038/jcbfm.1990.111
Involvement of Perivascular Sensory Fibers in the Pathophysiology of Cerebral Vasospasm following Subarachnoid Hemorrhage
L. Edvinsson (1990)
10.1016/0006-8993(83)90402-X
Immunohistochemical evidence for a substance P-containing trigeminovascular pathway to pial arteries in cats
L. Liu-Chen (1983)
10.1523/JNEUROSCI.02-11-01608.1982
"Increased" sensory stimulation leads to changes in energy-related enzymes in the brain
W. Dietrich (1982)
10.1038/jcbfm.1982.19
Nomogram for 2-Deoxyglucose Lumped Constant for Rat Brain Cortex
W. Pardridge (1982)
10.3171/jns.1977.46.4.0446
Effects of subarachnoid hemorrhage on cerebral blood volume, blood flow, and oxygen utilization in humans.
R. Grubb (1977)
10.1111/j.1471-4159.1977.tb10649.x
THE [14C]DEOXYGLUCOSE METHOD FOR THE MEASUREMENT OF LOCAL CEREBRAL GLUCOSE UTILIZATION: THEORY, PROCEDURE, AND NORMAL VALUES IN THE CONSCIOUS AND ANESTHETIZED ALBINO RAT 1
L. Sokoloff (1977)
10.1016/0006-8993(88)90152-7
Comparative effects of stimulation of the trigeminal ganglion and the superior sagittal sinus on cerebral blood flow and evoked potentials in the cat
G. Lambert (1988)
10.1002/ANA.410070305
Effects of manipulation of the sensorimotor system on focal motor seizures in the monkey
S. Hosokawa (1980)
10.1016/0090-3019(90)90004-9
Experimental isobaric subarachnoid hemorrhage: regional mitochondrial function during the acute and late phase.
F. Marzatico (1990)
10.1073/PNAS.86.4.1401
Trigeminovascular fibers increase blood flow in cortical gray matter by axon reflex-like mechanisms during acute severe hypertension or seizures.
D. Sakas (1989)
10.3171/JNS.1979.50.5.0587
Regional cerebral blood flow in patients with ruptured intracranial aneurysms.
R. Ishii (1979)
10.1523/JNEUROSCI.05-04-00874.1985
Metabolic alterations in rat somatosensory cortex following unilateral vibrissal removal
W. Dietrich (1985)
10.1016/0006-8993(87)90069-2
Cerebrovascular and metabolic changes during the delayed vasospasm following experimental subarachnoid hemorrhage in baboons, and treatment with a calcium antagonist
Christina Sahlin (1987)
10.1161/01.STR.6.6.707
Cerebrospinal Fluid and Arterial Lactate, Pyruvate and Acid‐Base Balance in Patients With Intracranial Hemorrhages
M. Fujishima (1975)
10.1523/JNEUROSCI.08-07-02468.1988
Enrichment of a vasoactive neuropeptide (calcitonin gene related peptide) in the trigeminal sensory projection to the intracranial arteries
T. O’Connor (1988)
Amine mechanisms in the cerebral circulation.
L. Edvinsson (1976)
10.1073/PNAS.72.9.3726
Central noradrenergic regulation of cerebral blood flow and vascular permeability.
M. Raichle (1975)
10.2307/2282359
Statistical analysis in psychology and education
G. A. Ferguson (1961)
10.1016/0361-9230(85)90077-2
Origin of cholinergic nerves to the rat major cerebral arteries: Coexistence with vasoactive intestinal polypeptide
H. Hara (1985)
10.1161/01.RES.28.4.426
Cerebral Ischemia and Reactive Hyperemia: Studies of Cortical Blood Flow and Microcirculation Before, During, and After Temporary occlusion of Middle Cerebral Artery of Squirrel Monkeys
T. Sundt (1971)
10.1073/PNAS.83.15.5731
Calcitonin gene-related peptide: functional role in cerebrovascular regulation.
J. McCulloch (1986)



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