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Dsc Screening For Drug-Drug Interactions In Poly Pharmaceuticals Intended For The Alleviation Of The Symptoms Of Colds And Flu. II.

S. Botha, A. P. Lötter, J. L. D. Preez
Published 1987 · Chemistry

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AbstractDSC screening for drug-drug interactions of a polypharmaceutical capsule dosage form containing salicylaminde, ascorbic acid, pyrilamine maleate and phenylephrine hydrochloride was performed. The results show the following:1. Ascorbic acid is incompatible with salicylamide, pyrilamine maleate and pheynylephrine hydrochloride.2. Salicylamide is incompatible with ascorbic acid, pyrilamine maleate and phenylephrine hydrochloride.3. Pyrilamine maleate is incompatible with ascorbic acid, salicylamide and phenylephrine hydrochloride.4. Phenylephrine hydrochloride is incompatible with salicylamide, pyrilamine maleate and ascorbic acid.
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