Online citations, reference lists, and bibliographies.

Prediction Of Proximal Femur Strength By A Quantitative Computed Tomography-based Finite Element Method—Creation Of Predicted Strength Data Of The Proximal Femur According To Age Range In A Normal Population

Masako Kaneko, Isao Ohnishi, Takuya Matsumoto, Satoru Ohashi, Masahiko Bessho, Naoto Hayashi, Sakae Tanaka
Published 2016 · Medicine
Cite This
Download PDF
Analyze on Scholarcy
Objective. The objective of this study was to investigate the factors that affect the predicted bone strength of proximal femur in Japanese population. Methods. Participants (552 men and 273 women) in a health checkup program with computed tomography (CT) at the University of Tokyo Hospital were enrolled in this study. Three-dimensional finite element models of the proximal femur were constructed from CT data of the participants with simultaneous scans of a calibration phantom containing hydroxyapatite rods. Multiple regression analysis was performed to analyze the relationship between the predicted bone strength and clinical factors. Results. Average predicted strength of proximal femur was lower in women than in men in all age ranges. Predicted bone strength in women under both stance and fall configurations significantly decreased with age, and that in men had the tendency to decrease with age. Body weight positively affected the predicted bone strength in both men and women. Conclusions. This is the first cross-sectional analysis of the predicted bone strength of the proximal femur in Japanese population of wide age range. Age and body weight critically affected bone strength of proximal femur determined by quantitative CT-based finite element method, in particular in women, under both stance and fall configurations.
This paper references
Femoral bone strength and its relation to cortical and trabecular changes after treatment with PTH, alendronate, and their combination as assessed by finite element analysis of quantitative CT scans.
Tony M. Keaveny (2008)
[Experimental study on the mechanism of femoral neck fractures].
Masato Fujii (1987)
Finite element analysis of the proximal femur and hip fracture risk in older men.
Eric S. Orwoll (2009)
Osteoporosis prevention, diagnosis, and therapy.
Anne Klibanski (2000)
Bone mineral content and mechanical strength
A Alho (1988)
Femoral strength is better predicted by finite element models than QCT and DXA.
Dianna D. Cody (1999)
Nonlinear finite element model predicts vertebral bone strength and fracture site. Spine (Phila Pa
K Imai (1976)
Prediction of the strength of the elderly proximal femur by bone mineral density and quantitative ultrasound measurements of the heel and tibia.
M.L. Bouxsein (1999)
Assessment of vertebral fracture risk and therapeutic effects of alendronate in postmenopausal women using a quantitative computed tomography-based nonlinear finite element method
Koshiro Imai (2008)
Predicting the compressive mechanical behavior of bone.
Tony S. Keller (1994)
QCT-based finite element models predict human vertebral strength in vitro significantly better than simulated DEXA
Enrico Dall’Ara (2011)
Impact direction from a fall influences the failure load of the proximal femur as much as age-related bone loss
Tupac Pinilla (2006)
Fracture of the human femoral neck: effect of density of the cancellous core.
J. Mizrahi (1984)
Osteoporosis prevention, diagnosis, and therapy.
Leo Lutwak (2001)
Prediction of femoral fracture load using automated finite element modeling.
Joyce H. Keyak (1997)
Fracture incidence and association with bone mineral density in elderly men and women: the Rotterdam Study.
Stephanie C E Schuit (2004)
Bone mineral content and mechanical strength. An ex vivo study on human femora at autopsy.
A. Alho (1988)
Biomechanical properties of the proximal femur determined in vitro by single-energy quantitative computed tomography.
Stephen I. Esses (1989)
Prediction of the strength and fracture location of the femoral neck by CT-based finite-element method: a preliminary study on patients with hip fracture
Masahiko Bessho (2004)
Nonlinear Finite Element Model Predicts Vertebral Bone Strength and Fracture Site
Kazuhiro Imai (2006)
Dual-energy projection radiography in the evaluation of femoral neck strength, density, and mineralization.
David J. Sartoris (1985)
Ultrasound and densitometry of the calcaneus correlate with the failure loads of cadaveric femurs
Mary L. Bouxsein (2004)
Prediction of strength and strain of the proximal femur by a CT-based finite element method.
Masahiko Bessho (2007)
Recent trends in the incidence and lifetime risk of hip fracture in Tottori, Japan
Hiroshi Hagino (2008)
Mechanical properties of trabecular bone from the proximal femur: a quantitative CT study.
Jeffrey C. Lotz (1990)
Correlations between orthogonal mechanical properties and density of trabecular bone: use of different densitometric measures.
Joyce H. Keyak (1994)
Diagnostic criteria for primary osteoporosis: year 2000 revision
Hajime Orimo (2001)
Diagnostic criteria for primary osteoporosis: year 2012 revision
Satoshi Soen (2013)

This paper is referenced by
High- and low-viscosity cement for osteoporotic femoral augmentation: A computational subject-specific approach
Samuel Jesús Ramos-Infante (2019)
Advanced Techniques of Bone Mass Measurements and Strength in Adults
Kyle K. Nishiyama (2018)
Development of Experimental and Finite Element Modelling Techniques for Investigation of Human Femurs
Caroline Elizabeth Meakin (2017)
Osteoarthritis Changes Hip Geometry and Biomechanics Regardless of Bone Mineral Density—A Quantitative Computed Tomography Study
Jerzy Narloch (2019)
Application of a model based on dual-energy X-ray absorptiometry and finite element simulation for predicting the probability of osteoporotic hip fractures to a sample of people over 60 years
Enrique Gil López (2015)
Prediction of the pathological fracture risk during stance and fall-loading configurations for metastases in the proximal femur, using a computed tomography-based finite element method.
Yusuke Shinoda (2019)
A predictive mechanical model for evaluating vertebral fracture probability in lumbar spine under different osteoporotic drug therapies
Enrique López (2016)
Bone strength of the proximal femur in healthy subjects with ossification of the posterior longitudinal ligament
Tomohumi Doi (2019)
Probability of osteoporotic vertebral fractures assessment based on DXA measurements and finite element simulation
Enrique Gil López (2014)
Potential bone fragility of mid-shaft atypical femoral fracture: Biomechanical analysis by a CT-based nonlinear finite element method.
Atsuhiro Tano (2019)
Quantitative Computed Tomography (QCT) derived Bone Mineral Density (BMD) in finite element studies: a review of the literature
Nikolas K. Knowles (2016)
Semantic Scholar Logo Some data provided by SemanticScholar