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Morphological Changes Of The Multifidus Muscle In Patients With Symptomatic Lumbar Disc Herniation.

Joerg Franke, Thomas Hesse, Clément Tournier, Walter Schuberth, Christian Mawrin, Jean Carles LeHuec, Henning Grasshoff
Published 2009 · Medicine
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OBJECT Lumbar disc herniations are associated with segmental muscle alterations of the ipsilateral segmental multifidus muscle. The aim of the present study was a histopathological analysis of the myopathological changes of the multifidus muscle and correlation with the duration of radicular symptoms. METHODS Multifidus muscle biopsies were performed in 20 patients during discectomy. Specimens were obtained from the area of the multifidus muscle innervated by the nerve from the level of the affected disc. Histopathological findings were classified according as neurogenic tissue syndrome and nonspecific myopathological syndrome, and these results were correlated with the duration of radicular symptoms. RESULTS Results of multifidus muscle biopsies were classified as neurogenic tissue syndrome in 12 patients and as nonspecific myopathological syndrome in 8. The mean (+/- SD) duration of radicular symptoms was 10.75 +/- 7.9 months in patients with neurogenic tissue syndrome and 4.37 +/- 3.9 months in patients with a nonspecific myopathological syndrome. There was a positive correlation between group assignment and symptom duration (correlation coefficient 0.457, p = 0.043). CONCLUSIONS A long duration of radicular symptoms is associated with a neurogenic tissue syndrome, whereas a nonspecific myopathological tissue syndrome is seen in patients with shorter duration of symptoms. This suggests that patients with long duration of radicular symptoms originating from a lumbar disc herniation have an increased risk for neurogenic muscular changes, and that consideration should be given to an earlier surgical intervention.
This paper references
10.1097/00007632-199612010-00011
Multifidus Muscle Recovery Is Not Automatic After Resolution of Acute, First‐Episode Low Back Pain
Julie A. Hides (1996)
10.1097/00007632-200103150-00012
Histochemical Changes in the Multifidus Muscle in Patients With Lumbar Intervertebral Disc Herniation
Kiyoshi Yoshihara (2001)
10.1097/00007632-198709000-00004
1987 Volvo Award in Basic Science: The Morphology of the Lumbar Erector Spinae
J E Macintosh (1987)
10.1097/00007632-199501150-00011
Stability Increase of the Lumbar Spine With Different Muscle Groups: A Biomechanical In Vitro Study
Hans Joachim Wilke (1995)
10.1007/s005860000189
Influence of age and duration of symptoms on fibre type distribution and size of the back muscles in chronic low back pain patients
A. F. Mannion (2000)
10.1097/01.bsd.0000163819.61680.4a
Influence of Facet and Posterior Muscle Degeneration on Clinical Results of Lumbar Total Disc Replacement: Two-Year Follow-Up
Jean-Charles Le Huec (2005)
10.1007/s001130050651
Bilateraler Funktionsverlust der Quadrizepsmuskulatur nach einseitiger Kreuzbandruptur mit Begleitverletzung durch zentrales Aktivierungsdefizit
Dietmar Urbach (2000)
10.1007/s00586-008-0867-7
Timing of surgery for sciatica: subgroup analysis alongside a randomized trial
Wilco C. Peul (2008)
10.1056/NEJMoa064039
Surgery versus prolonged conservative treatment for sciatica.
Wilco C. Peul (2007)
10.1097/00007632-198904000-00008
Histochemistry and Morphology of Erector Spinae Muscle in Lumbar Disc Herniation
Xiao Zhong Zhu (1989)
10.1097/00007632-199809150-00003
Importance of the Intersegmental Trunk Muscles for the Stability of the Lumbar Spine: A Biomechanical Study In Vitro
Ulrich Quint (1998)
10.1097/00007632-199304000-00008
The Lumbar Multifidus Muscle Five Years After Surgery for a Lumbar Intervertebral Disc Herniation
Jussi Rantanen (1993)
10.1097/01.brs.0000144405.11661.eb
Changes in the Cross-Sectional Area of Multifidus and Psoas in Patients With Unilateral Back Pain: The Relationship to Pain and Disability
Karen L. Barker (2004)
10.1002/ar.1092070407
A quantitative ultrastructural analysis of satellite cells in denervated fast and slow muscles of the mouse.
Mikel H. Snow (1983)
10.1097/00007632-198609000-00013
The Multifidus Muscle in Patients with Lumbar Disc Herniation: A Histochemical and Morphometric Analysis of Intraoperative Biopsies
Mikko Mattila (1986)
10.1016/J.MATH.2006.07.017
Multifidus size and symmetry among chronic LBP and healthy asymptomatic subjects.
Julie A. Hides (2008)
10.3233/BMR-2006-19101
Changes of muscular fibre types in erector spinae and multifidus muscles in the unstable lumbar spine
Jiří Matějka (2006)
10.1006/dbio.1996.0097
Satellite cell proliferative compartments in growing skeletal muscles.
Edward K. Schultz (1996)
10.1097/01.brs.0000248453.51165.0b
Rapid Atrophy of the Lumbar Multifidus Follows Experimental Disc or Nerve Root Injury
Paul William Hodges (2006)
10.1097/00007632-199401001-00009
Evidence of lumbar multifidus muscle wasting ipsilateral to symptoms in patients with acute/subacute low back pain.
Julie A. Hides (1994)
10.1097/00007632-200009010-00009
Histochemistry and Morphology of the Multifidus Muscle in Lumbar Disc Herniation: Comparative Study Between Diseased and Normal Sides
Wei-guo Zhao (2000)



This paper is referenced by
10.1016/j.msksp.2019.01.016
Neuromuscular morphometric characteristics in low back pain with unilateral radiculopathy caused by disc herniation: An ultrasound imaging evaluation.
Hadi Sarafraz (2019)
10.1016/j.clineuro.2019.105629
Lumbar lordosis reduction and disc bulge may correlate with multifidus muscle fatty infiltration in patients with single-segment degenerative lumbar spinal stenosis
Youwen Liu (2020)
10.1016/j.spinee.2012.08.020
Is level- and side-specific multifidus asymmetry a marker for lumbar disc pathology?
Michele Battie (2012)
10.1016/B978-0-12-805186-3.00024-2
Vitamin D and Disc Herniation Associated Pain
Mansour Sedighi (2017)
10.3389/fvets.2018.00016
Magnetic Resonance Imaging Signal Alterations in Paraspinal Muscles in Dogs with Acute Thoracolumbar Intervertebral Disk Extrusion
Péter Trampus (2018)
10.1177/0300060519853430
Evaluation of lumbar multifidus muscle in patients with lumbar disc herniation: are complex quantitative MRI measurements needed?
Bulent Colakoglu (2019)
10.1007/s00256-015-2252-z
Lumbar multifidus muscle changes in unilateral lumbar disc herniation using magnetic resonance imaging
Naime Altınkaya (2015)
10.1007/s00590-012-1167-9
Iatrogenic injury to the erector spinae during posterior lumbar spine surgery: underlying anatomical considerations, preventable root causes, and surgical tips and tricks
Zhi-Jun Hu (2012)
10.1016/j.wneu.2018.05.019
Volumetric Muscle Measurements Indicate Significant Muscle Degeneration in Single-Level Disc Herniation Patients.
Kaan Yaltırık (2018)
ASSESSMENT OF THE CORRELATION BETWEEN LUMBAR DISC HERNIATION WITH THE VOLUME OF THE PARASPINAL MUSCLES AND THE DEGREE OF ADIPOSITY
Ümmühan Özelçi (2016)
10.1186/1745-6215-15-373
Role of vitamin D3 in Treatment of Lumbar Disc Herniation—Pain and Sensory Aspects: Study Protocol for a Randomized Controlled Trial
Mahsa Sedighi (2014)
10.1097/BSD.0000000000000029
Two-Level Circumferential Lumbar Fusion Comparing Midline and Paraspinal Posterior Approach: 5-Year Interim Outcomes of a Randomized, Blinded, Prospective Study
Glenn Buttermann (2015)
10.1136/bmjopen-2016-012426
Motor control exercise for symptomatic lumbar disc herniation: protocol for a systematic review and meta-analysis
Mohammad Reza Pourahmadi (2016)
10.3340/jkns.2011.50.3.201
Changes in the cross-sectional area of multifidus and psoas in unilateral sciatica caused by lumbar disc herniation.
Wook Kim (2011)
10.1002/jum.14854
Shear Wave Elastography of the Lumbar Multifidus Muscle in Patients With Unilateral Lumbar Disk Herniation.
Deniz Alis (2019)
10.1016/j.spinee.2013.08.003
An evidence-based clinical guideline for the diagnosis and treatment of lumbar disc herniation with radiculopathy.
David S. Kreiner (2014)
10.3233/BMR-181304
Relationship between straight leg-raising test measurements and area of fat infiltration in multifidus muscles in patients with lumbar disc hernation.
Yuxian Zhong (2019)
10.1007/s00590-011-0781-2
Minimally invasive posterior surgery for thoracolumbar fractures. New trends to decrease muscle damage
Yann Philippe Charles (2011)
10.1002/jum.14661
Reliability of Real‐time Ultrasound Imaging for the Assessment of Trunk Stabilizer Muscles: A Systematic Review of the Literature
Morteza Taghipour (2019)
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