Online citations, reference lists, and bibliographies.
Please confirm you are human
(Sign Up for free to never see this)
← Back to Search

Comparison Of Activation Patterns In Mirror Neurons And The Swallowing Network During Action Observation And Execution: A Task-Based FMRI Study

Y. Jing, Tuo Lin, Wanqi Li, C. Wu, X.-P. Li, Qian Ding, Man-feng Wu, G. Xu, Yue Lan
Published 2020 · Medicine

Save to my Library
Download PDF
Analyze on Scholarcy
Share
Background Observation of a goal-directed motor action can excite the respective mirror neurons, and this is the theoretical basis for action observation (AO) as a novel tool for functional recovery during stroke rehabilitation. To explore the therapeutic potential of AO for dysphagia, we conducted a task-based functional magnetic resonance imaging (fMRI) study to identify the brain areas activated during observation and execution of swallowing in healthy participants. Methods Twenty-nine healthy volunteers viewed the following stimuli during fMRI scanning: an action-video of swallowing (condition 1, defined as AO), a neutral image with a Chinese word for “watching” (condition 2), and a neutral image with a Chinese word for “swallowing” (condition 3). Action execution (AE) was defined as condition 3 minus condition 2. One-sample t-tests were performed to define the brain regions activated during AO and AE. Results Many brain regions were activated during AO, including the middle temporal gyrus, inferior frontal gyrus, pre- and postcentral gyrus, supplementary motor area, hippocampus, brainstem, and pons. AE resulted in activation of motor areas as well as other brain areas, including the inferior parietal lobule, vermis, middle frontal gyrus, and middle temporal gyrus. Two brain areas, BA6 and BA21, were activated with both AO and AE. Conclusion The left supplementary motor area (BA6) and left middle temporal gyrus (BA21), which contains mirror neurons, were activated in both AO and AE of swallowing. In this study, AO activated mirror neurons and the swallowing network in healthy participants, supporting its potential value in the treatment of dysphagia.
This paper references
10.1155/2018/2321045
The Activation of the Mirror Neuron System during Action Observation and Action Execution with Mirror Visual Feedback in Stroke: A Systematic Review
Jack J Q Zhang (2018)
10.1038/nrgastro.2015.199
Oropharyngeal dysphagia: manifestations and diagnosis
N. Rommel (2016)
10.1007/s00455-016-9769-8
25 Years of Dysphagia Rehabilitation: What Have We Done, What are We Doing, and Where are We Going?
C. Easterling (2016)
10.1152/JN.1999.81.4.1917
Identification of the cerebral loci processing human swallowing with H2(15)O PET activation.
S. Hamdy (1999)
Contextualizing action
L. Amoruso (2018)
10.1177/1545968312471905
Reduction of Bradykinesia of Finger Movements by a Single Session of Action Observation in Parkinson Disease
E. Pelosin (2013)
Therapeutic intervention in oropharyngeal
R. Martino (2016)
Learning from goal and action
G Jegatheeswaran (2019)
10.1038/nrn.2016.135
The mirror mechanism: a basic principle of brain function
G. Rizzolatti (2016)
10.1073/PNAS.89.13.5951
Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging.
S. Ogawa (1992)
Effect of parent-delivered
E. Kirkpatrick
10.1016/j.cub.2013.10.051
What We Know Currently about Mirror Neurons
J. M. Kilner (2013)
10.1016/j.neuroscience.2010.07.015
Variability in the effector-specific pattern of motor facilitation during the observation of everyday actions: implications for the clinical use of action observation
S. Hétu (2010)
Functional brain imaging of swallowing: an activation likelihood estimation meta-analysis. Hum. Brain Mapp
P Soros (2009)
10.1007/s00455-009-9211-6
Brain Stem Control of the Phases of Swallowing
I. M. Lang (2009)
10.1016/j.pmr.2008.07.001
Dysphagia in stroke and neurologic disease.
M. González-Fernández (2008)
10.1152/JN.2001.85.2.938
Cerebral cortical representation of automatic and volitional swallowing in humans.
R. Martin (2001)
10.1007/s00455-016-9779-6
History of the Use and Impact of Compensatory Strategies in Management of Swallowing Disorders
C. Lazarus (2016)
10.1016/j.neuroimage.2005.08.063
Strategies for block-design fMRI experiments during task-related motion of structures of the oral cavity
D. Soltysik (2006)
10.1523/JNEUROSCI.3481-17.2018
Mirror Neuron Populations Represent Sequences of Behavioral Epochs During Both Execution and Observation
Kevin A Mazurek (2018)
10.1016/j.neuroimage.2013.02.009
Selective enhancement of motor cortical plasticity by observed mirror-matched actions
M. V. Sale (2013)
10.1007/978-1-62703-380-0_15
Dysphagia in Stroke
Brian J. Hedman (2013)
10.1073/pnas.1404652111
Mirror neurons
J. Marshall (2014)
10.1017/S0140525X13000903
Mirror neurons: from origin to function.
R. Cook (2014)
10.1038/nrgastro.2016.127
Therapeutic intervention in oropharyngeal dysphagia
R. Martino (2016)
10.1111/j.1467-8624.2011.01717.x
Observation and initiation of joint action in infants.
C. Fawcett (2012)
10.2209/TDCPUBLICATION.50.169
Visual and auditory stimuli associated with swallowing: an FMRI study.
Takeshi Kawai (2009)
Dysphagia: current reality and scope
R. Shaker (2015)
10.1007/s00455-017-9794-2
Swallowing Preparation and Execution: Insights from a Delayed-Response Functional Magnetic Resonance Imaging (fMRI) Study
J. A. Toogood (2017)
10.1152/ajpgi.1999.277.1.G219
Cortical activation during human volitional swallowing: an event-related fMRI study.
S. Hamdy (1999)
10.1098/rstb.2015.0361
What is feasible with imaging human brain function and connectivity using functional magnetic resonance imaging
K. Ugurbil (2016)
10.1002/hbm.20680
Functional brain imaging of swallowing: An activation likelihood estimation meta‐analysis
Peter Sörös (2009)
10.1093/cercor/bht190
Training the Motor Cortex by Observing the Actions of Others During Immobilization
M. Bassolino (2014)
10.1007/s00455-019-09985-w
Effects of Motor Imagery and Visual Neurofeedback on Activation in the Swallowing Network: A Real-Time fMRI Study
S. Kober (2019)
10.1016/j.neuroscience.2017.06.052
Two different mirror neuron networks: The sensorimotor (hand) and limbic (face) pathways
P. Ferrari (2017)
10.1002/dev.20504
The mirror neuron system and treatment of stroke.
S. Small (2012)
10.1038/nrgastro.2015.49
Dysphagia: current reality and scope of the problem
P. Clavé (2015)
10.1007/s11682-016-9635-1
Right sensory-motor functional networks subserve action observation therapy in aphasia
T. Gili (2016)
10.1523/JNEUROSCI.2705-14.2014
Mirror Neuron Activation Prior to Action Observation in a Predictable Context
M. Maranesi (2014)
The mirror neuron system : a fresh view
A. Casile (2011)
10.1155/2018/4897276
Effect of Group-Based Rehabilitation Combining Action Observation with Physiotherapy on Freezing of Gait in Parkinson's Disease
E. Pelosin (2018)
10.1007/BF02407219
The physiology of swallowing
W. Dodds (2006)
10.1007/s00455-012-9399-8
Visual and Auditory Stimuli Associated with Swallowing Activate Mirror Neurons: A Magnetoencephalography Study
Takashi Ushioda (2012)
10.1097/NRL.0B013E318272F811
Brain Repair After Stroke
G. Wittenberg (2012)
10.1016/s0304-3975(00)00359-5
25 Years
M. Nivat (2001)
rehabilitation : what have we done , what are we doing , and where are we going ?
C. Ertekin (2011)
10.1111/dmcn.13109
Effect of parent‐delivered action observation therapy on upper limb function in unilateral cerebral palsy: a randomized controlled trial
E. Kirkpatrick (2016)
10.1016/J.SCIB.2019.05.008
RESTplus: an improved toolkit for resting-state functional magnetic resonance imaging data processing
Xi-Ze Jia (2019)
10.1146/annurev.neuro.27.070203.144230
The mirror-neuron system.
G. Rizzolatti (2004)
Action observation and mirror neuron
M. Franceschini (2012)
10.1016/j.neuroimage.2013.01.037
Functional connectivity of the cortical swallowing network in humans
A. Babaei (2013)
10.3156/jsoft.22.1_109_1
ミラーニューロン(Mirror neuron)
敦命 鈴木 (2010)
10.1002/14651858.CD011887.pub2
Action observation for upper limb rehabilitation after stroke.
Lorenna Rdm Borges (2018)
Effects of motor imagery
S. E. 1111dmcn.13109 Kober (2019)
Conflict of Interest: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest
Jing (2018)
10.1016/j.bjorl.2015.08.006
Functional magnetic resonance and swallowing: critical literature review.
M. Lima (2015)
10.1136/jnnp.59.4.454
Functional brain imaging.
J. Meyer (1995)
10.1016/S1388-2457(03)00237-2
Neurophysiology of swallowing
C. Ertekin (2003)
10.1007/springerreference_137519
Swallowing disorders.
J. Logemann (2007)
10.1111/brv.12310
Mirror neurons in the tree of life: mosaic evolution, plasticity and exaptation of sensorimotor matching responses
Antonella Tramacere (2017)
10.1038/72991
A multimodal cortical network for the detection of changes in the sensory environment
J. Downar (2000)
10.1016/j.cognition.2017.10.024
Sensorimotor training alters action understanding
C. Catmur (2018)
10.1016/j.neuroimage.2018.05.020
Contextualizing action observation in the predictive brain: Causal contributions of prefrontal and middle temporal areas
L. Amoruso (2018)
Strategies for block-design fMRI
D. A. 222 Soltysik (2006)
10.1016/j.neuroscience.2019.02.019
Learning from Goal and Action Based Observations Differentially Modulates Functional Motor Cortical Plasticity
M. Vesia (2019)
10.1007/s00455-010-9319-8
Voluntary Versus Spontaneous Swallowing in Man
C. Ertekin (2010)
Action observation and mirror neuron network: a tool for motor stroke rehabilitation.
P. Sale (2012)
10.1038/nrneurol.2013.222
Brain repair after stroke—a novel neurological model
S. Small (2013)
10.1016/j.cub.2009.08.026
Mirror neurons
C. Keysers (2009)



Semantic Scholar Logo Some data provided by SemanticScholar