Online citations, reference lists, and bibliographies.
← Back to Search

Dissociative Symptomatology In Cancer Patients

C. Civilotti, L. Castelli, L. Binaschi, M. Cussino, V. Tesio, Giulia Di Fini, F. Veglia, R. Torta
Published 2015 · Psychology, Medicine

Cite This
Download PDF
Analyze on Scholarcy
Share
Introduction: The utilization of the post-traumatic stress disorder (PTSD) diagnostic spectrum is currently being debated to categorize psychological adjustment in cancer patients. The aims of this study were to: (1) evaluate the presence of cancer-related traumatic dissociative symptomatology in a sample of cancer patients; (2) examine the correlation of cancer-related dissociation and sociodemographic and medical variables, anxiety, depression, and post-traumatic stress symptomatology; (3) investigate the predictors of cancer-related dissociation. Methods: Ninety-two mixed cancer patients (mean age: 58.94, ds = 10.13) recruited from two hospitals in northern Italy were administered a questionnaire on sociodemographic and medical characteristics, the Karnofsky Scale to measure the level of patient activity and medical care requirements, the Hospital Anxiety and Depression Scale (HADS) to evaluate the presence of anxiety and depression, the Impact of Event Scale Revised (IES-R) to assess the severity of intrusion, avoidance, and hypervigilance, and the Peritraumatic Dissociative Experiences Questionnaire (PDEQ) to quantify the traumatic dissociative symptomatology. Results: 31.5% of participants report a PDEQ score above the cutoff. The results indicated that dissociative symptomatology was positively correlated with HADS scores (HADS-Anxiety: r = 0.476, p < 0.001; HADS-Depression: r = 0.364, p < 0.001) and with IES-R scores (IES-R-Intrusion: r = 0.698, p < 0.001; IES-R-Avoidance: r = 0.619, p < 0.001; IES-R- Hypervigilance: r = 0.681, p < 0.001). A stepwise regression analysis was performed in order to find the predictors of cancer-related traumatic dissociative symptomatology. The results converged on a three predictor model revealing that IES-R-Intrusion, IES-R-Avoidance, and IES-R-Hyperarousal accounted for 53.9% of the explained variance. Conclusion: These findings allow us to hypothesize a specific psychological reaction which may be ascribed to the traumatic spectrum within the context of cancer, emphasizing the close relationship between the origin of dissociative constituents which, according to the scientific literature, compose the traumatic experience. Our results have implications for understanding dissociative symptomatology in a cancer population and can help develop clinical programs of prevention and support for patients.
This paper references
10.1002/pon.1771
Perceived threat and PTSD symptoms in women undergoing surgery for gynecologic cancer or benign conditions
D. Posluszny (2011)
10.3109/00048679509064964
Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV)
G. Mendelson (2009)
10.1300/J229v08n01_04
Is Peritraumatic Dissociation a Risk Factor for PTSD?
Doris C Breh (2007)
The existential plight
J. W. Worden (1976)
Relations among psychological trauma
J. F. Thayer (1999)
10.1002/pon.2053
Relationship of sense of coherence to stressful events, coping strategies, health status, and quality of life in women with breast cancer
Elisabeth Kenne Sarenmalm (2013)
10.1016/j.socscimed.2008.10.037
Pathways to distress: the multiple determinants of depression, hopelessness, and the desire for hastened death in metastatic cancer patients.
G. Rodin (2009)
La Sofferenza Psichica in Oncologia. Modalità di intervento
G Morasso (2005)
Diagnostic and Statistical Manual of Mental Disorders, 5th Edn
(2013)
10.1002/pon.3208
A pilot randomized controlled trial of a brief early intervention for reducing posttraumatic stress disorder, anxiety and depressive symptoms in newly diagnosed head and neck cancer patients
M. Kangas (2013)
10.1093/ACREFORE/9780199975839.013.104
Diagnostic and Statistical Manual of Mental Disorders
J. Williams (2013)
10.1016/S0272-7358(98)00103-2
Relations among psychological trauma, dissociative phenomena, and trauma-related distress: a review and integration.
B. Gershuny (1999)
10.1159/000348610
Posttraumatic Stress Disorder in Female Cancer Patients: An Inappropriate Diagnosis in Oncology?
E. Greimel (2013)
10.1200/JCO.2014.32.15_SUPPL.E20557
A meta-analysis of prevalence rates and moderating factors for cancer-related post-traumatic stress disorder.
Gareth Abbey (2014)
Traumatic distress
J. A. Søreide (1996)
10.1111/j.1440-1614.2004.01480.x
Trauma-related dissociation: conceptual clarity lost and found.
O. van der Hart (2004)
10.1007/978-1-4615-2820-3_4
Stress Response Syndromes
M. Horowitz (1976)
10.1054/bjoc.2001.1724
Psychiatric morbidity and its recognition by doctors in patients with cancer
L. Fallowfield (2001)
10.4081/REUMATISMO.2007.304
[Hospital anxiety and depression].
A. R. Carone (2007)
An fMRI investigation of emotional
J. D. Cohen (2001)
10.2214/AJR.183.2.1830267
Fear of cancer.
L. Berlin (2004)
10.1017/S095026880700831X
Ethnic difference in the relationship between acute inflammation and serum ferritin in US adult males.
Y. Pan (2008)
Posttraumatic stress disorder in women breast cancer survivors treated with high-dose chemotherapy and autologous hematopoietic progenitor stem cell transplant
K Roper (2000)
10.1176/AJP.154.8.1114
Full and partial posttraumatic stress disorder: findings from a community survey.
M. Stein (1997)
10.1200/JCO.2013.49.8212
Posttraumatic stress and psychological growth in children with cancer: has the traumatic impact of cancer been overestimated?
S. Phipps (2014)
Dissociation and the fragmentary nature
B. A. van der Kolk (1995)
Dissociation in trauma: a new
E. R. NCCN. Nijenhuis (2011)
Posttraumatic stress disorder in women breast cancer survivors
K. Roper (2000)
Quality of life and personality traits in patients with malignant
(2013)
Posttraumatic stress disorder in female cancer
(2013)
10.3389/fpsyg.2012.00344
Toward a Neurobiology of Unrealistic Optimism
P. Shah (2012)
Psicotraumatologiae Psicologia dell'emergenza. Salerno: Ecomind
M Giannantonio (2003)
A pilot randomized
M. Kangas (2013)
Posttraumatic stress disorder in female cancer
(2013)
10.3389/fpsyg.2014.01419
Helping traumatized people survive: a psychoanalytic intervention in a contaminated site
Fanny Guglielmucci (2014)
Quality of life and personality traits in patients with malignant
(2013)
10.2147/NDT.S48965
Quality of life and personality traits in patients with malignant pleural mesothelioma and their first-degree caregivers
A. Granieri (2013)
Psycho-oncology, 2nd ed.
J. C. Holland (2010)
10.1016/J.YGYNO.2006.08.036
Long-term survival from gynecologic cancer: psychosocial outcomes, supportive care needs and positive outcomes.
K. Hodgkinson (2007)
10.2190/UQ2G-UGV1-3PPC-6387
The Existential Plight in Cancer: Significance of the First 100 Days
A. Weisman (1976)
Psicotraumatologiae Psicologia dell'emergenza
M Giannantonio (2003)
10.1007/BF02102887
Dissociation and the fragmentary nature of traumatic memories: Overview and exploratory study
B. Kolk (1995)
10.1002/pon.1481
Fear of cancer progression and cancer‐related intrusive cognitions in breast cancer survivors
A. Mehnert (2009)
10.1002/(SICI)1099-1611(199603)5:1<1::AID-PON197>3.0.CO;2-V
Traumatic distress symptoms in early breast cancer I: Acute response to diagnosis
L. Tjemsland (1996)
Adjustment to cancercoping or personal transition ?
A. D. Brown (2001)
10.4135/9781849209953
Statistical methods for geography
P. Rogerson (2001)
10.1007/s10865-013-9497-6
Resilience in the year after cancer diagnosis: a cross-lagged panel analysis of the reciprocity between psychological distress and well-being
W. K. Hou (2013)
10.1080/09658211.2013.807842
Episodic and semantic components of autobiographical memories and imagined future events in post-traumatic stress disorder
A. Brown (2014)
Diagnostic and Statistical Manual of Mental Disorders, 4th Edn
(2000)
La Sofferenza Psichica in Oncologia. Modalità di intervento. Roma, IT: Carocci Editore. National Comprehensive Cancer Network
G Morasso (2005)
The Hospital Anxiety and Depression Scale.
G. Huston (1987)
10.1126/SCIENCE.1062872
An fMRI Investigation of Emotional Engagement in Moral Judgment
J. Greene (2001)
Fear of cancer.
D. F. Harrison (1980)
The peritraumatic dissociative
T. Metzler (2004)
10.1016/S0022-3999(01)00296-3
The validity of the Hospital Anxiety and Depression Scale. An updated literature review.
I. Bjelland (2002)
Dissociative symptomatology in cancer patients
C Citation Civilotti (2015)
10.1038/136239a0
The Frontiers of Psychology
J. Mann (1935)
10.1080/15299732.2011.570592
Dissociation in Trauma: A New Definition and Comparison with Previous Formulations
E. Nijenhuis (2011)
The clinical evaluation of chemotherapeutic agents in cancer
Da Karnofsky (1949)
10.1016/S1836-9553(10)70029-1
Impact of Event Scale-revised.
H. Motlagh (2010)
10.1002/pon.3654
A meta-analysis of prevalence rates and moderating factors for cancer-related post-traumatic stress disorder
Gareth Abbey (2015)
Diagnostic and Statistical Manual of Mental Disorders, 5th ed.
M. J. Carter (2014)
10.1016/0005-7967(95)00058-6
Who develops PTSD from motor vehicle accidents?
E. Blanchard (1996)
10.1002/PON.1057
Prevalence of acute and post‐traumatic stress disorder and comorbid mental disorders in breast cancer patients during primary cancer care: a prospective study
A. Mehnert (2007)
10.1200/JCO.1993.11.11.2279
General information tapes inhibit recall of the cancer consultation.
S. Dunn (1993)
10.1111/j.1365-2354.2012.01344.x
A comparison of the clinical determinants of health-related quality of life and subjective well-being in long-term breast cancer survivors.
P. Tessier (2012)
10.1002/1099-1611(200101/02)10:1<1::AID-PON484>3.0.CO;2-T
Adjustment to cancer—coping or personal transition?
J. Brennan (2001)
10.1080/j.1440-1614.2004.01480.x
Trauma-Related Dissociation: Conceptual Clarity Lost and Found
O. van der Hart (2004)
10.1016/S0005-7967(99)00181-3
The causal link between self-reported trauma and dissociation: a critical review.
H. Merckelbach (2001)
10.1097/00000421-198806000-00019
Quality‐of‐Life Assessment in Cancer Patients
J. Ochs (1988)
A meta-analysis of prevalence rates and moderating factors for cancer-related posttraumatic stress disorder. Psychooncology doi: 10.1002/pon.3654 [Epub ahead of print
G. Abbey (2014)
10.1176/APPI.AJP.158.12.1982
Efficacy and safety of paroxetine treatment for chronic PTSD: a fixed-dose, placebo-controlled study.
R. Marshall (2001)
10.1155/2006/136945
The Validity of the Hospital Anxiety and Depression Scale and the Geriatric Depression Scale in Parkinson’s Disease
F. Mondolo (2006)
Emotional distress in patients
B. Bultz (2006)
10.1037/T07470-000
The Peritraumatic Dissociative Experiences Questionnaire.
C. Marmar (2011)
10.1002/jts.21901
Posttraumatic stress symptoms in breast cancer patients: temporal evolution, predictors, and mediation.
Sandra Pérez (2014)
10.1287/MKSC.1070.0286
The Value of Quality
G. Tellis (2007)
10.1176/APPI.PSY.43.4.259
Stress response syndromes and cancer: conceptual and assessment issues.
M. Gurevich (2002)
Efficacy and safety of paroxetine treatment for chronic PTSD : a fixeddose , placebo - controlled study
J. Wilson (2001)
10.1093/med/9780195367430.003.0047
Posttraumatic stress disorder associated with cancer diagnosis and treatment
M. Andrykowski (2010)
10.1007/978-0-387-70990-1_10
The Impact of Event Scale: Revised
D. Weiss (2007)
10.1016/S0272-7358(01)00118-0
Posttraumatic stress disorder following cancer. A conceptual and empirical review.
M. Kangas (2002)
Assessing psychological trauma and PTSD, 2nd ed.
J. Wilson (2004)
10.1016/S1548-5315(11)70702-1
Emotional distress in patients with cancer: the sixth vital sign
B. Bultz (2006)
10.1016/j.jpainsymman.2012.04.003
Emotional numbness modifies the effect of end-of-life discussions on end-of-life care.
P. Maciejewski (2013)
10.1054/bjoc.2000.1545
How successful are oncologists in identifying patient distress, perceived social support, and need for psychosocial counselling?
W. Söllner (2001)
10.1007/S10332-005-0056-4
Réponses post-traumatiques et dissociation en oncologie
A. Ronson (2005)
Posttraumatic stress disorder in women breast cancer survivors treated with high - dose chemotherapy and autologous hematopoietic progenitor stem cell transplant
K. E. Sarenmalm (2000)
10.1007/BF02868440
Psychiatric morbidity
P. Singhal (1988)



This paper is referenced by
10.1891/1933-3196.10.3.215
EMDR and CBT: A Comparative Clinical Study With Oncological Patients
E. Faretta (2016)
10.1177/0886260517693000
Gender Differences in the Prediction of Acute Stress Disorder From Peritraumatic Dissociation and Distress Among Victims of Violent Crimes
Julie Boisclair Demarble (2017)
10.3389/fpsyt.2020.00201
Posttraumatic Stress Disorder Symptoms in Lymphoma Patients: A Prospective Study
Claire Camille (2020)
10.1016/J.EJTD.2018.04.004
PTSD post-diagnostic du cancer : « déni » ou amnésie dissociative ?
I. Saillot (2018)
10.1891/1933-3196.11.4.102
Thérapie EMDR et psycho-oncologie : un pont entre le corps et l'esprit
E. Faretta (2017)
10.1891/1933-3196.10.3.153
Neurobiological Impact of EMDR in Cancer
S. Carletto (2016)
10.1037/hea0000524
Evaluation of Coping as a Mediator of the Relationship Between Stressful Life Events and Cancer-Related Distress
Dale J. Langford (2017)
10.3390/ijerph17114151
COVID-19 Pandemic in the Italian Population: Validation of a Post-Traumatic Stress Disorder Questionnaire and Prevalence of PTSD Symptomatology
G. Forte (2020)
10.1002/cncr.32477
Perceived stress is associated with a higher symptom burden in cancer survivors
M. Mazor (2019)
10.1002/pon.5010
Investigating the impact of self‐management behaviours on quality of life and fear of recurrence in head and neck cancer survivors: A population‐based survey
Simon Dunne (2019)
10.1016/j.jpainsymman.2018.08.017
Phenotypic Characterization of Paclitaxel-Induced Peripheral Neuropathy in Cancer Survivors.
K. Kober (2018)
10.1891/1933-3196.10.3.138
EMDR Therapy in Psycho-Oncology: A Bridge Between Mind and Body
E. Faretta (2016)
10.1891/1933-3196.11.3.92
El impacto neurobiológico de EMDR en el cáncer
S. Carletto (2017)
10.1080/07347332.2018.1440276
The association of metacognitive beliefs with emotional distress and trauma symptoms in adolescent and young adult survivors of cancer
P. Fisher (2018)
10.3389/fpsyg.2015.00947
Editorial: PsychOncology: clinical psychology for cancer patients—Cancer: the key role of clinical psychology
L. Castelli (2015)
10.1891/1933-3196.10.3.162
EMDR Therapy Protocol for Oncological Patients
E. Faretta (2016)
10.1016/j.jpainsymman.2018.02.021
Associations Between Perceived Stress and Chemotherapy-Induced Peripheral Neuropathy and Otoxicity in Adult Cancer Survivors.
C. Miaskowski (2018)
10.1007/s11764-017-0662-8
Impact of chemotherapy-induced neurotoxicities on adult cancer survivors’ symptom burden and quality of life
C. Miaskowski (2017)
10.37336/2707-0700-2019-4-2
Problems of depression and auto-aggressive manifestations in cancer patients
N. Otroshchenko (2019)
10.1097/NCC.0000000000000713
Psychological Symptoms and Stress Are Associated With Decrements in Attentional Function in Cancer Patients Undergoing Chemotherapy
M. Atallah (2019)
10.1111/BJP.12170
Massive Trauma in A Community Exposed to Asbestos: Thinking and Dissociation among the Inhabitants of Casale Monferrato
F. Borgogno (2015)
10.1007/s00520-015-2960-x
Acute stress trajectories 1 year after a breast cancer diagnosis
S. Pérez (2015)
10.1016/j.jpsychores.2020.109939
Prevalence of post-traumatic stress disorder among Lithuanian breast cancer patients and its risk factors.
Jurgita Kazlauskiene (2020)
Neurobiological Correlates of Posttraumatic Stress Disorder in Oncological Diseases
Sara Carletto (2016)
10.1891/1933-3196.12.2.E21
Impact neurobiologique de l’EMDR dans le cancer
S. Carletto (2018)
10.1080/14779757.2020.1717988
Emotion-focused perspective on breast cancer patients’ experiences of comorbid anxiety and depression: a qualitative case analysis of three clients’ in-session presentations
Joana Hissa (2020)
10.1080/10926771.2017.1331942
Prediction of Posttraumatic Stress Disorder From Peritraumatic Dissociation and Distress Among Men and Women Victims of Violent Crimes
Julie Boisclair Demarble (2018)
10.1002/npr2.12025
Frequency of mental disorders among chronic pain patients with or without fibromyalgia in Japan
K. Miki (2018)
Semantic Scholar Logo Some data provided by SemanticScholar