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Constituents Of Psoralea Corylifolia Fruits And Their Effects On Methicillin-Resistant Staphylococcus Aureus

Yanmei Cui, S. Taniguchi, T. Kuroda, T. Hatano
Published 2015 · Chemistry, Medicine

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Two new flavonoids, bakuisoflavone (1) and bakuflavanone (2), together with 15 known compounds, were isolated from the fruits of Psoralea corylifolia, and their structures were characterized by spectroscopic data. The effects of the isolated compounds on methicillin-resistant Staphylococcus aureus were also examined. We found that two compounds, isobavachalcone (10) and bakuchiol (12), showed noticeable antibacterial effects on the MRSA strains examined. Quantitation of the major constituents, including anti-MRSA constituents, was then performed. The results showed individual contents of 1.26%–16.49% (w/w) among the examined compounds in the ethyl acetate extract from P. corylifolia fruits.
This paper references
Some new flavonoids from psoralea corylifolia
V. K. Bhalla (1968)
Meroterpenoids—I : Psoralea corylifolia Linn.—1. Bakuchiol, a novel monoterpene phenol
G. Mehta (1973)
Induced isoflavonoids from copper chloride-treated stems of Pueraria lobata
T. Hakamatsuka (1991)
Antiplatelet flavonoids from seeds of Psoralea corylifolia.
W. Tsai (1996)
Bakuchiol derivatives from the leaves of Psoralea glandulosa
C. Labbé (1996)
Psoralen and other linear furanocoumarins as phytoalexins in Glehnia littoralis
T. Masuda (1998)
Phenolic constituents of Cassia seeds and antibacterial effect of some naphthalenes and anthraquinones on methicillin-resistant Staphylococcus aureus.
T. Hatano (1999)
Phenolic constituents of licorice. VIII. Structures of glicophenone and glicoisoflavanone, and effects of licorice phenolics on methicillin-resistant Staphylococcus aureus.
T. Hatano (2000)
Immunomodulatory and antitumour properties of Psoralea corylifolia seeds.
P. Latha (2000)
In Vitro Antimicrobial Activities of Bakuchiol against Oral Microorganisms
Harumi Katsura (2001)
Antibacterial prenylflavone derivatives from Psoralea corylifolia, and their structure-activity relationship study.
Sheng Yin (2004)
An efficient new method for extraction, separation and purification of psoralen and isopsoralen from Fructus Psoraleae by supercritical fluid extraction and high-speed counter-current chromatography.
X. Wang (2004)
Flavonoids in Leguminosae: Analysis of extracts of T. pratense L., T. dubium L., T. repens L., and L. corniculatus L. leaves using liquid chromatography with UV, mass spectrometric and fluorescence detection
E. Rijke (2004)
corniculatus L. leaves using liquid chromatography with UV, mass spectrometric and fluorescence detection
E De Rijke (2004)
Antioxidants from a Chinese medicinal herb--Psoralea corylifolia L
Guo Jiangning (2005)
Fingerprint analysis of Psoralea corylifolia L. by HPLC and LC-MS.
L. Zhao (2005)
In vitro antimalarial activity of prenylated flavonoids from Erythrina fusca
Pranorm Khaomek (2007)
Bisbakuchiols A and B, novel dimeric meroterpenoids from Psoralea corylifolia
Cheng Zhu Wu (2007)
Synthesis and structure-immunosuppressive activity relationships of bakuchiol and its derivatives.
H. Chen (2008)
Inhibition of Human 20S Proteasome by Compounds from Seeds of Psoralea corylifolia
Y. Kim (2009)
Glycosidase inhibitory phenolic compounds from the seed of Psoralea corylifolia
K. Y. Oh (2010)
Isolation of antioxidants from Psoralea corylifolia fruits using high-speed counter-current chromatography guided by thin layer chromatography-antioxidant autographic assay.
G. Xiao (2010)
Estrogenic activities of Psoralea corylifolia L. seed extracts and main constituents.
S. Lim (2011)
A New Prenylated Flavanone from Derris trifoliata Lour
C. Jiang (2012)
Antibacterial activity of chalcones, hydrazones and oxadiazoles against methicillin-resistant Staphylococcus aureus.
Thaís Moreira Osório (2012)
Antimicrobial Activity of Psoralea corylifolia Linn . ( Baguchi ) Seeds Extracts by Organic Solvents and Supercritical Fluids
Chopra Bhawna (2013)
Structures of Two New Flavonoids and Effects of Licorice Phenolics on Vancomycin-Resistant Enterococcus Species
Eerdunbayaer (2014)
Structures of New Phenolics Isolated from Licorice, and the Effectiveness of Licorice Phenolics on Vancomycin-Resistant Enterococci
Eerdunbayaer (2014)
First reporting of methicillin-resistant Staphylococcus aureus (MRSA) ST398 in an industrial rabbit holding and in farm-related people.
F. Agnoletti (2014)
Bakuchiol, a novel monoterpene phenol
G. Mehta
Sample Availability: Samples of compounds 6, 12, 16 and 17 are available from the authors
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons

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Naturally occurring prenylated chalcones from plants: structural diversity, distribution, activities and biosynthesis.
K. Zhou (2021)
Diacylglycerol acyltransferase inhibitory new meroterpenes from the seeds of Psoralea corylifolia, and their structure-activity relationship study.
Meng-Xue Xiu (2021)
Potential determinants for metabolic fates and inhibitory effects of isobavachalcone involving in human cytochrome P450, UDP-glucuronosyltransferase enzymes, and efflux transporters.
Zifei Qin (2021)
Isobavachalcone ameliorates cognitive deficits, and Aβ and tau pathologies in triple-transgenic mice with Alzheimer's disease.
Mohan Zhang (2021)
Corylifol A from Psoralea corylifolia L. Enhances Myogenesis and Alleviates Muscle Atrophy
Y. Han (2020)
Metabolism and disposition of corylifol A from Psoralea corylifolia: metabolite mapping, isozyme contribution, species differences and identification of efflux transporters for corylifol A-O-glucuronide in HeLa1A1 cells
Yang Li (2020)
Cullen corylifolium (L.) Medicus (Fabaceae/Leguminosae)
Shahid Akbar (2020)
Quality Control of Psoralea corylifolia L. Based on High-Speed Countercurrent Chromatographic Fingerprinting
Xiaoxue Wu (2020)
Two new meroterpenes with activity against diacylglycerol acyltransferase from seeds of Psoralea corylifolia
D. Wang (2020)
Chemical constituents from the fruits of Psoralea corylifolia and their protective effects on ionising radiation injury
J. Du (2019)
Antibacterial activity of flavonoids and their structure–activity relationship: An update review
F. Farhadi (2019)
Genus Psoralea: A review of the traditional and modern uses, phytochemistry and pharmacology
B. Koul (2019)
Recent developments of chalcones as potential antibacterial agents in medicinal chemistry.
Wenjia Dan (2019)
Bakuchiol: A newly discovered warrior against organ damage
Zhenlong Xin (2019)
Evaluación del halo de inhibición de la planta Otholobium mexicanum frente a Staphylococcuss aureaus ATCC 25923
Vanessa Romero (2019)
A new bioactive coumestan from the seeds of Psoralea corylifolia
M. Chai (2019)
A review on medicinal plant extracts and their active ingredients against methicillin-resistant and methicillin-sensitive Staphylococcus aureus
Marzieh Askarinia (2019)
Chemical constituents from the fruits of Cullen corylifolium (L.) Medik. by the targeted separation mode
Xiangyue Liu (2019)
Progress of Bakuchiol in the Field of Cosmetics
Huibin Zhu (2019)
Exploration of Unani concept of blood purifying drugs and likely models for its screening
Ansari Mushir (2019)
Psoralea corylifolia L: Ethnobotanical, biological, and chemical aspects: A review
Fiaz Alam (2018)
Non-microbial Natural Products That Inhibit Drug-Resistant Staphylococcus aureus
Jactty Chew (2018)
Multi-Target Anti-Alzheimer Activities of Four Prenylated Compounds from Psoralea Fructus
Qingxia Xu (2018)
New Application of Psoralen and Angelicin on Periodontitis With Anti-bacterial, Anti-inflammatory, and Osteogenesis Effects
X. Li (2018)
Four new compounds isolated from Psoralea corylifolia and their diacylglycerol acyltransferase (DGAT) inhibitory activity.
X. Lin (2018)
General survey of Fructus Psoraleae from the different origins and chemical identification of the roasted from raw Fructus Psoraleae.
Jun-jun Yang (2018)
Licorice as a Resource for Pharmacologically Active Phenolic Substances: Antioxidant and Antimicrobial Effects
T. Hatano (2017)
Phytochemical study of Bituminaria basaltica aerial parts, an Italian endemism
R. V. Bandeira Reidel (2017)
Rapid separation and simultaneous quantitative determination of 13 constituents in Psoraleae Fructus by a single marker using high-performance liquid chromatography with diode array detection.
Y. Zhang (2017)
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