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Nanosuspensions In Nanobiomedicine

Muthukrishnan Lakshmipathy, Anima Nanda

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The tremendous success in developing new nanomaterials and fostering technological innovation arises from the focus on interdisciplinary research and collaboration between physical and medical scientists. The concept of nano-medicine is one of the most important and exciting ideas ever generated by the applications of nanoscience. One of the most challenging tasks in the pharmaceutical industry is the formulation of poorly soluble drugs. The implication of conventional techniques for improving the solubility has gained limited success. Nanoparticles facilitate formulation with improved solubility and efficacy mainly through nanosuspension approach. Techniques such as media milling, high-pressure homogenization, and use of microemulsion have been used for production of nanosuspensions for a novel delivery system. Moreover, they are manoeuvred to patient-acceptable dosage forms like tablets, capsules, and lyophilized powder products. Nanosuspension technology has also been studied for active and passive targeted drug delivery systems, which the chapter highlights on various formulational perspectives and applications as a biomedicine delivery system.