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Personalized Approach In Nanomedicine

Maria Vlasova, Boris V. Smirin

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This chapter characterizes need for new patient-specific approaches in medicine. The authors here illustrate role of nanomedicine and particularly nanotheranostics, combining diagnostic and therapeutic functions, in the paradigm of personalized disease treatment. This chapter discusses current insights regarding the mechanisms of nano-bio interactions and the origin of adverse effects of nanoformulations. Furthermore, this chapter illustrates possible reasons behind an individual physiological response to a given nanomedicine, such as type and stage of disease, physiological conditions and lifestyle of a patient. Finally, a review of possible approaches for the initial choice of nanoformulation, suitable for a given patient is provided at the end of the chapter.