Online citations, reference lists, and bibliographies.
Please confirm you are human
(Sign Up for free to never see this)
← Back to Search

LC-Mass As A Complementary Method In Detecting Drug-Excipient Incompatibility Of Pharmaceutical Products

F. Monajjemzadeh
Published 2014 · Chemistry

Save to my Library
Download PDF
Analyze on Scholarcy
Share
Copyright: © 2014 Monajjemzadeh F. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited Stability of a drug in a pharmaceutical formulation is a critical issue and should be guaranteed by the manufacturer prior to commercialization of a product. Regulatory authorities in each country are responsible for carefully monitoring the compliance with the accepted guidelines for example the ICH ones [1]. Formulator pharmacists of pharmaceutical industries always make sure about the drug stability in “preformulation” process [2].
This paper references
10.1023/A:1025478129417
Drug-excipient compatibility studies by physico-chemical techniques; The case of Atenolol
A. Marini (2003)
10.1016/S0731-7085(97)00103-9
Characterisation of impurities in bulk drug batches of fluticasone propionate using directly coupled HPLC-NMR spectroscopy and HPLC-MS.
N. Mistry (1997)
10.1021/JS980434G
Selection of solid dosage form composition through drug-excipient compatibility testing.
A. T. Serajuddin (1999)
10.1081/PDT-120027414
Amlodipine Besylate–Excipients Interaction in Solid Dosage Form
A. Abdoh (2004)
10.1016/J.SAA.2005.07.020
Background defining during the imine formation reaction in FT-IR liquid cell.
H. Namli (2006)
10.1016/J.JPBA.2006.10.013
LC and LC-MS study of stress decomposition behaviour of isoniazid and establishment of validated stability-indicating assay method.
H. Bhutani (2007)
404-413
F Monajjemzadeh (2014)
10.1016/J.JPBA.2004.10.008
Thermal analysis study of the interactions between acetaminophen and excipients in solid dosage forms and in some binary mixtures.
M. Tomassetti (2005)
Amlodipine besylateexcipients interaction in solid dosage
A Abdoh (2004)
10.1055/s-0033-1354364
Spray drying as a fast and simple technique for the preparation of extended release dipyridamole (DYP) microparticles in a fixed dose combination (FDC) product with aspirin.
H. Hamishehkar (2014)
10.1016/0378-5173(94)00374-E
Utilization of differential scanning calorimetry as a screening technique to determine the compatibility of ketoprofen with excipients
P. Mura (1995)
10.1007/S10943-005-7257-9
Application of DSC and NIRS to study the compatibility of metronidazole with different pharmaceutical excipients
D. Kiss (2006)
Electrospray ionization mass spectrometry : fundamentals, instrumentation, and applications
R. Cole (1997)
10.1021/JS9702067
Maillard reaction of lactose and fluoxetine hydrochloride, a secondary amine.
D. D. Wirth (1998)
10.1016/j.jpba.2013.06.016
Drug-excipient compatibility screening--role of thermoanalytical and spectroscopic techniques.
R. Chadha (2014)
Incompatibilities of Pharmaceutical Excipients with Active Pharmaceutical Ingredients: A Comprehensive Review
Sonali S Bharate (2010)
10.1016/J.JPBA.2005.02.026
Selection of excipients for extended release formulations of glipizide through drug-excipient compatibility testing.
R. Verma (2005)
10.1002/1520-6017(200007)89:7<920::AID-JPS9>3.0.CO;2-W
Liquid chromatography-mass spectrometry and proton nuclear magnetic resonance characterization of trace level condensation products formed between lactose and the amine-containing diuretic hydrochlorothiazide.
P. Harmon (2000)
10.1016/j.ejpb.2009.06.012
Compatibility studies of acyclovir and lactose in physical mixtures and commercial tablets.
F. Monajjemzadeh (2009)
10.1002/JPS.2600800127
Drug Stability: Principles and Practices
J. Mcginity (1991)
Aulton's pharmaceutics: the design and manufacture of medicines
Me Aulton (2007)
10.1016/J.JPBA.2007.09.014
Study of forced degradation behavior of enalapril maleate by LC and LC-MS and development of a validated stability-indicating assay method.
S. Bhardwaj (2008)
10.3109/03639049109044268
A Comparison of diffuse Reflectance Ft-Ir Spectroscopy and Dsc in the Characterization of a Drug-Excipient Interaction
K. J. Hartauer (1991)
Detection of gabapentin-lactose Maillard reaction product (Schiff's Base): Application to solid dosage form preformulation. Part 1
F. Monajjemzadeh (2011)
10.1208/s12249-009-9248-8
Assessment of Feasibility of Maillard Reaction between Baclofen and Lactose by Liquid Chromatography and Tandem Mass Spectrometry, Application to Pre Formulation Studies
F. Monajjemzadeh (2009)
10.1016/S0731-7085(01)00475-7
The ICH guidance in practice: stress degradation studies on ornidazole and development of a validated stability-indicating assay.
M. Bakshi (2001)
10.1248/BPB.25.547
Current developments in LC-MS for pharmaceutical analysis.
C. Lim (2002)



This paper is referenced by
Semantic Scholar Logo Some data provided by SemanticScholar