← Back to Search
Mesothelioma Mortality Surveillance And Asbestos Exposure Tracking In Italy.
L. Fazzo, G. Minelli, M. De Santis, C. Bruno, A. Zona, A. Marinaccio, S. Conti, R. Pirastu, P. Comba
Published 2012 · Geography, Medicine
Download PDFAnalyze on Scholarcy
INTRODUCTION Spatial distribution of mortality from pleural mesothelioma (which in the ICD-10 Revision has a specific code: C45.0) in Italy for the period 2003-2009 is described. Previous mortality studies at national level employed the topographic code "Malignant neoplasms of pleura", because of unavailability of a specific code in ICD-9 Revision for pleural mesothelioma. METHODS Standardized mortality ratios were computed for all municipalities, using each regional population as reference; for municipalities in Regions with rate higher than the national rate, the latter has been used as reference. SMRs were computed specifically also for each Italian Polluted Sites "of national concern for environmental remediation" (IPS) with asbestos exposure sources, composed by one or more municipalities, using regional rate as reference. Spatial Scan Statistics procedure, using SatScan software, was applied in cluster analysis: the country was divided into geographic macro-areas and the relative risks (RR) express the ratio of risk within the cluster to the risk of the macro-area outside the cluster. Clusters with p-value < 0.10 were selected. RESULTS The national standardized annual mortality rate was 1.7 cases per 100 000. Several areas with evident burden of asbestos-related disease were detected. Significant clusters were found in correspondence to asbestos-cement industries (e.g. Casale Monferrato, women: RR = 28.7), shipyards (e.g. Trieste, men: RR = 4.8), petrochemical industries (e.g. Priolo, men: RR = 6.9) and a stone quarry contaminated by fluoro-edenite fibres (Biancavilla, women: RR = 25.9). Some of the increased clusters correspond to IPS. CONCLUSIONS The results may contribute to detect asbestos exposure and to set priorites for environmental remediation.
This paper references
Asbestos-related mesothelioma in Monfalcone, Italy.
C. Bianchi (1993)
Accuracy of death certification of pleural mesothelioma in Italy
C. Bruno (2004)
Analysis of latency time and its determinants in asbestos related malignant mesothelioma cases of the Italian register.
A. Marinaccio (2007)
Mortality from malignant pleural neoplasms in Italy in the years 1988-1992. Roma: Istituto Superiore di Sanità
Di Paola (1996)
Malignant mesothelioma of the pleura in Trieste, Italy.
L. Giarelli (1992)
Asbestos related diseases in Italy: an integrated approach to identify unexpected professional or environmental exposure risks at municipal level
A. Marinaccio (2008)
ItAly orIgInAl ArtIcles And reVIews
A historical cohort mortality study among shipyard workers in Genoa, Italy.
R. Puntoni (2001)
Environmental household exposures to asbestos and occurrence of pleural mesothelioma.
D. Dodoli (1992)
Cancer mortality in a cohort of asbestos textile workers
E. Pira (2005)
SENTIERI Project. Mortality study of residents in Italian polluted sites: evaluation of the epidemiological evidence.
R. Pirastu (2010)
The relationship between malignant mesothelioma and an asbestos cement plant environmental risk: a spatial case–control study in the city of Bari (Italy)
M. Musti (2009)
cancer in Syracuse (Italy), from 2002 to 2005. Registro Territoriale di Patologia aUSL 8
A Madeddu (2009)
[Asbestos import in Italy: the transit through Livorno harbour from 1957 to 1995].
A. Nemo (2009)
A spatial scan statistic
M. Kulldorff (1997)
Survival of pleural malignant mesothelioma in Italy: A population‐based study
F. Montanaro (2009)
[Statistical analysis of the incidence of some cancers in the province of Taranto 1999-2001].
G. Graziano (2009)
Cancer Mortality and Incidence of Mesothelioma in a Cohort of Wives of Asbestos Workers in Casale Monferrato, Italy
D. Ferrante (2007)
[Mortality in a cohort of asbestos cement workers in Carrara, Italy].
Ilaria Raffaelli (2007)
Pleural Mesothelioma Cases in Biancavilla are Related to a New Fluoro-Edenite Fibrous Amphibole
P. Comba (2003)
Pleural mesothelioma mortality and asbestos exposure mapping in Italy.
L. Fazzo (2012)
[Mortality from tumors and other diseases of the respiratory system in cement-asbestos workers in Casale Monferrato. A historical cohort study].
C. Magnani (1987)
[Mesothelioma of the pleura in the Province of Trieste].
C. Bianchi (2007)
Survival of peritoneal malignant mesothelioma in Italy: A population‐based study
D. Mirabelli (2009)
SENTIERI project: mortality study of residents in Italian polluted sites – IPS
R. Pirastu (2011)
International Agency for Research on Cancer.
E. Somers (1985)
Modeling Mesothelioma Risk Associated with Environmental Asbestos Exposure
M. Maule (2007)
[Malignant mesothelioma in Emilia-Romagna: incidence and asbestos exposure].
L. Mangone (2002)
[Pleural mesotheliomas in the Po River valley near Pavia; mortality, incidence and the correlations with an asbestos cement plant].
C. Magnani (1994)
[Cause-specific mortality of asbestos-cement workers compensated for asbestosis in the city of Bari].
S. Belli (1998)
Italian asbestos mapping. World Asbestos conference
F Paglietti (2009)
Spatial Scan Statistic
Pemetaan Jumlah Balita (2014)
The mesotheliomas related to asbestos used in Italian railway : report of 199 cases
S Belli (2002)
[Mortality in a cohort of asbestos cement workers in Bari].
V. Coviello (2002)
[Mortality from malignant pleural neoplasms in Broni (Pavia), 1980-1997].
P. Amendola (2003)
Mortality study of residents in Italian polluted sites. Results
R Pirastu (2011)
Italian asbestos mapping
R Pirastu (2009)
Mesothelioma and lung tumors attributable to asbestos among petroleum workers.
V. Gennaro (2000)
Predictions of mortality from pleural mesothelioma in Italy: A model based on asbestos consumption figures supports results from age‐period‐cohort models
A. Marinaccio (2005)
A historical cohort mortality study among workers in Genoa, Italy
R Puntoni (2001)
cancer in Syracuse ( Italy ) , from 2002 to 2005
The mesotheliomas related to asbestos used in Italian railway: report of 199 cases
C Maltoni (2002)
Is the ratio of pleural mesothelioma mortality to pleural cancer mortality approximately unity for Italy? Considerations from the oldest regional mesothelioma register in Italy
G. Gorini (2002)
The mesotheliomas related to asbestos used in Italian railway : report of 199 cases
Maltoni c (2002)
Asbestos fibre burden in the lungs of patients with mesothelioma who lived near asbestos-cement factories.
P. Barbieri (2012)
[Incidence of malignant mesothelioma in Piedmont, 1990-2001].
D. Mirabelli (2007)
A historical cohort mortality study among workers in Genoa , Italy
D Dodoli (2001)
[Territorial distribution of mortality from malignant tumors of the pleura in Italy].
M. Di Paola (1992)
Diffuse Pleural Mesothelioma in Trieste. A Survey Based on Autopsy Cases
C. Bianchi (1978)
Pleural malignant mesothelioma epidemic: Incidence, modalities of asbestos exposure and occupations involved from the Italian National Register
A. Marinaccio (2012)
Industrial pollution and pleural cancer mortality in Spain.
G. López-Abente (2012)
Asbestos exposure in malignant mesothelioma of the pleura: a survey of 557 cases.
C. Bianchi (2001)
* - Bari -Fibronit 49 199 (155-253) 26 189 (133-262) 17 192 (122-287) 17 279 (178-419) Biancavilla 6 439 (191-867)
Mortality from malignant pleural neoplams in Italy
M Mastrantonio (1988)
This paper is referenced by
ASBESTOS IN CONTAMINATED SITES : OCCUPATIONAL AND ENVIRONMENTAL EXPOSURES , PRIORITIES FOR REMEDIATION
Rapporti ISTISAN (2015)
Sarcomatoid Mesothelioma: Future Advances in Diagnosis, Biomolecular Assessment, and Therapeutic Options in a Poor-Outcome Disease
D. Galetta (2016)
Epidemiological surveillance of mesothelioma mortality in Italy.
L. Fazzo (2018)
Silicosis mortality in Italy: temporal trends 1990-2012 and spatial patterns 2000-2012.
G. Minelli (2017)
The next mesothelioma wave: mortality trends and forecast to 2030 in Brazil.
E. Algranti (2015)
The Drive For Self-Assertion And The Reality Principle In A Patient With Malignant Pleural Mesothelioma: The History of Giulia*
A. Granieri (2017)
Prevalence of anti-nuclear autoantibodies in subjects exposed to natural asbestiform fibers: a cross-sectional study
C. Ledda (2018)
Geographical patterns of mesothelioma incidence and asbestos exposure in Lombardy, Italy.
C. Mensi (2016)
Update of in vitro, in vivo and ex vivo fluoro-edenite effects on malignant mesothelioma: A systematic review (Review)
V. Filetti (2020)
YKL-40 and mesothelin in the blood of patients with malignant mesothelioma, lung cancer and asbestosis.
M. Corradi (2013)
Peritoneal mesothelioma in Italy: Trends and geography of mortality and incidence.
S. Conti (2015)
Massive Trauma in A Community Exposed to Asbestos: Thinking and Dissociation among the Inhabitants of Casale Monferrato
F. Borgogno (2015)
Community exposure to asbestos in Casale Monferrato: from research on psychological impact to a community needs-centered healthcare organization.
A. Granieri (2015)
Extreme trauma in a polluted area: Bonds and relational transformations in an Italian community
A. Granieri (2016)
Environmental and health data needed to develop national surveillance systems in industrially contaminated sites.
P. Martín-Olmedo (2018)
The fibres with fluoro-edenitic composition in Biancavilla (Sicily, Italy): health impact and clues for environmental remediation.
P. Comba (2014)
Detection of pleural plaques in workers exposed to inhalation of natural fluoro-edenite fibres.
V. Rapisarda (2015)
Helping traumatized people survive: a psychoanalytic intervention in a contaminated site
Fanny Guglielmucci (2014)
Mesothelioma in Italy: the Casale Monferrato model to a national epidemiological surveillance system.
P. Comba (2018)
Asbestos in Belgium: an underestimated health risk. The evolution of mesothelioma mortality rates (1969–2009)
Laura Van den Borre (2014)
Impact of an asbestos cement factory on mesothelioma incidence in a community in Italy.
D. Consonni (2019)
Mesothelin is more useful in pleural effusion than in serum in the diagnosis of pleural mesothelioma.
P. Ferro (2013)
Health impact of the exposure to fibres with fluoro-edenitic composition on the residents in Biancavilla (Sicily, Italy): mortality and hospitalization from current data.
S. Conti (2014)
Pleural mesothelioma: Case-report of uncommon occupational asbestos exposure in a small furniture industry.
E. Oddone (2016)
Use of GIS in visualization of work-related health problems
M. Delaunay (2015)
Asbestos case and its current implications for global health.
D. Marsili (2013)
Advancing Global Health through Environmental and Public Health Tracking
P. Lauriola (2020)
Approche géographique appliquée au Réseau National de Vigilance et de Prévention des Pathologies Professionnelles (RNV3P). (Geographic approach applied to the French national occupational disease surveillance and prevention network (RNV3P))
M. Delaunay (2015)
Communication and health education in communities experiencing asbestos risk and health impacts in Italy.
D. Marsili (2019)
Non-occupational exposure to asbestos and risk of pleural mesothelioma: review and meta-analysis
G. Marsh (2017)
Living in Contaminated Sites: Which Cost for Psychic Health?
F. Guglielmucci (2015)
Impact of an asbestos cement factory on mesothelioma incidence: global assessment of effects of occupational, familial, and environmental exposure.
C. Mensi (2015)See more