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Antioxidant Activity Of β-Glucan

K. Kofuji, A. Aoki, K. Tsubaki, M. Konishi, T. Isobe, Y. Murata
Published 2012 · Medicine, Biology

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β-Glucans extracted from barley, which mainly contains β-(1,3-1,4)-D-glucan, are used extensively as supplements and food additives due to their wide biologic activities, including a reduction in blood lipid level. In this study, the antioxidant activity of β-glucan was examined to assess potential new benefits associated with β-glucan, because oxidative stress is considered one of the primary causal factors for various diseases and aging. β-Glucan extracted from barley was found to possess significant antioxidant activity. The amount of antioxidant activity was influenced by different physiologic properties (e.g., structure and molecular size) of β-glucan, which varied depending on the source and extraction method used. The antioxidant activity of β-glucan was significantly higher than that of various polymers that are used as food additives. These results indicate that β-glucan has promise as a polymeric excipient for supplement and food additive with antioxidant and other benefits, which may contribute to enhancing health and beauty.
This paper references
[Oxidative stress profile: OSP].
H. Ochi (2003)
10.1093/JN/129.5.942
Short-chain fatty acids suppress cholesterol synthesis in rat liver and intestine.
H. Hara (1999)
10.1016/0144-8617(83)90019-X
Water-soluble (1→3), (1→4)-β-D-glucans from barley (Hordeum vulgare) endosperm. II. Fine structure
J. Woodward (1983)
10.1093/JN/130.2.243
Low levels of viscous hydrocolloids lower plasma cholesterol in rats primarily by impairing cholesterol absorption.
M. Levrat-Verny (2000)
10.1370/afm.917
The Effects of Barley-Derived Soluble Fiber on Serum Lipids
R. Talati (2009)
FDA allows barley products to claim reduction in risk of coronary heart disease
FDA News Release (2005)
10.1080/07315724.2008.10719722
Physiological Effects of Concentrated Barley β-Glucan in Mildly Hypercholesterolemic Adults
Kristen N Smith (2008)
Barley β-glucan and its physiological function
K. Tsubaki (2003)
[Oxidative stress and atherosclerosis].
T. Osawa (1997)
10.1007/s10719-008-9147-3
Structural characterisation and biological activities of a unique type β-d-glucan obtained from Aureobasidium pullulans
R. Tada (2008)
10.1016/J.JCS.2005.11.001
Glucose and insulin responses in healthy men to barley bread with different levels of (1 -> 3;1 -> 4)-beta-glucans; predictions using fluidity measurements of in vitro enzyme digests
Elin Östman (2006)
10.1017/S0007114507682968
The effects of concentrated barley beta-glucan on blood lipids in a population of hypercholesterolaemic men and women.
J. Keenan (2007)
An Evaluation of the Immunological Activities of Commercially Available β1, 3-Glucans
V. Vetvicka (2007)
FDA News Release , “ FDA allows barley products to claim reduction in risk of coronary heart disease
E. Rossi Östman (2005)
10.1002/HEP.1840200612
Mechanism of serum cholesterol reduction by oat bran
J. Marlett (1994)
FDA allows barley products to claim reduction in risk of coronary heart disease
Fda News (2005)
10.1016/J.FOODCHEM.2005.04.039
Antioxidant activity and nutrient composition of selected cereals for food use
S. Ragaee (2006)
10.4327/JSNFS.40.61
Protective effects of barley flour on water-immersion-induced stress ulcer in rats.
H. Nakamura (1987)



This paper is referenced by
10.21475/AJCS.2017.11.01.296
Accumulation of antioxidants in rice callus (Oryza sativa L.) induced by β-glucan and salt stress
A. N. Alhasnawi (2017)
NUTRACEUTICAL FUNCTIONS OF BETA-GLUCANS
M. Drywień (2019)
10.1016/j.ijbiomac.2017.12.055
Physicochemical properties, production, and biological functionality of poly-γ-d-glutamic acid with constant molecular weight from halotolerant Bacillus sp. SJ-10.
J. Lee (2018)
10.4239/wjd.v5.i3.267
Functional foods-based diet as a novel dietary approach for management of type 2 diabetes and its complications: A review.
P. Mirmiran (2014)
10.1080/13880209.2017.1299767
Intracerebroventricular administration of the (1→6)-β-d-glucan (lasiodiplodan) in male rats prevents d-penicillamine-induced behavioral alterations and lipoperoxidation in the cortex
Carlos Ricardo Maneck Malfatti (2017)
10.1016/j.lwt.2020.109955
Changes in protein profile, bioactive potential and enzymatic activities of gluten-free flours obtained from hulled and dehulled oat varieties as affected by germination conditions
Natalia Aparicio-García (2020)
UNIVERSIDADE FEDERAL DO AMAZONAS - UFAM PROGRAMA MULTI-INSTITUCIONAL DE PÓS-GRADUAÇÃO EM BIOTECNOLOGIA
Karen Kelly Carvalho de Oliveira (2013)
10.21608/EAJBSZ.2018.13428
Effects of Mannan-oligosaccharide and β-Glucan Prebiotic on the Brain Oxidant/Antioxidant Balance in Broilers under Natural Egyptian Summer Conditions
Sohair M. M. Rageb (2018)
10.1186/s12979-016-0068-x
β-glucans: ex vivo inflammatory and oxidative stress results after pasta intake
A. Barera (2016)
10.1016/J.BCDF.2017.03.001
Structural, rheological and nutraceutical potential of β-glucan from barley and oat
A. Shah (2017)
10.11118/actaun202068010119
The Utilization of Vegetable and Fruit Wastes for Saccharomyces cerevisieae Cell Wall Based β-Glucan Production with Antioxidant Activity
G. L. Utama (2020)
10.12911/22998993/110790
β-Glucan-Mediated Alleviation of NaCl Stress in Ocimum basilicum L. in Relation to the Response of Antioxidant Enzymes and Assessment DNA Marker
A. N. Alhasnawi (2019)
10.1016/J.BCAB.2017.04.016
Relationship observed between salinity-tolerant callus cell lines and anatomical structure of Line 2 (Oryza sativa L.) indica under salinity stress
A. N. Alhasnawi (2017)
Effect of Omega-3 on Ovarian Tissue and Blastocyst Formation on Diabetic Rats In Vitro
M. Shahi (2017)
10.3389/fphys.2018.00246
Chamazulene Attenuates ROS Levels in Bovine Aortic Endothelial Cells Exposed to High Glucose Concentrations and Hydrogen Peroxide
Giulia Querio (2018)
10.1111/and.13088
The effects of dietary restriction and administration of β‐glucan from Euglena gracilis on the sperm characteristics and reproductive organs of rats
Fusun Ak Sonat (2018)
10.5138/09750185.2229
Antioxidant, anti-cholinesterase, anti-α-glucosidase and prebiotic properties of beta-glucan extracted from Algerian barley
Saâd Mebrek (2018)
10.1093/jrr/rrs119
Arabinoxylan rice bran (MGN-3/Biobran) provides protection against whole-body γ-irradiation in mice via restoration of hematopoietic tissues
M. Ghoneum (2013)
10.3390/antiox9050375
Time-Dependent Indirect Antioxidative Effects of Oat Beta-Glucans on Peripheral Blood Parameters in the Animal Model of Colon Inflammation
Łukasz Kopiasz (2020)
Resistance elements of small grain cereals against Fusarium head blight and contribution of Health Promoting Compounds
Charlotte Martin (2017)
10.1016/j.scitotenv.2015.07.041
An environmental management industrial solution for the treatment and reuse of mussel wastewaters.
M. Prieto (2015)
10.1038/s41598-017-03053-9
Aureobasidium pullulans produced β-glucan is effective to enhance Kurosengoku soybean extract induced Thrombospondin-1 expression
Daisuke Muramatsu (2017)
Synergistic Effects of Humic Acid and Glucan in Hepatoprotection against Experimental Liver Injury
Vetvicka (2014)
IMMUNOMODULATORY EFFECT OF BETA GLUCAN ON NEUTROPHIL FUNCTIONS IN DIABETES MELLITUS- AN IN VITRO STUDY
(2018)
10.5455/jice.20150519103113
Prophylactic effects of humic acid-glucan combination against experimental liver injury
V. Vetvicka (2015)
10.1016/j.carbpol.2015.07.099
A water soluble β-glucan of an edible mushroom Termitomyces heimii: Structural and biological investigation.
Dilip K. Manna (2015)
10.1007/978-3-030-42319-3_4
Bioactive Carbohydrates, Biological Activities, and Sources
T. Oyedepo (2020)
Study on Estimation, Extraction and Analysis of Barley Beta-glucan
V. Kayal (2014)
10.1016/j.ijbiomac.2020.03.046
Effect of beta- and alpha-glucans on immune modulating factors expression in enterocyte-like Caco-2 and goblet-like LS 174T cells.
B. De Felice (2020)
10.1016/j.bcab.2019.101425
Bioactive polysaccharides from natural sources: A review on the antitumor and immunomodulating activities
Indranil Chakraborty (2019)
Influence of Immunobeta® Dietary Supplementation on Egg Production and Some Parameters of Oxidative Stress in Laying Hens
V. Gerzilov (2019)
10.4172/2155-9546.1000240
The Efficacy of Prebiotic (β-Glucan) as a Feed Additive against Toxicity of Aflatoxin B1 in Common Carp, Cyprinus Carpio L.
J. K. Al-Faragi (2014)
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